"Nitrofurantoin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A urinary anti-infective agent effective against most gram-positive and gram-negative organisms. Although sulfonamides and antibiotics are usually the agents of choice for urinary tract infections, nitrofurantoin is widely used for prophylaxis and long-term suppression.
| Descriptor ID |
D009582
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| MeSH Number(s) |
D02.640.600.566 D03.383.312.649.566
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Nitrofurantoin".
Below are MeSH descriptors whose meaning is more specific than "Nitrofurantoin".
This graph shows the total number of publications written about "Nitrofurantoin" by people in this website by year, and whether "Nitrofurantoin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Nitrofurantoin" by people in Profiles.
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Wu E, Kuehl TJ, Danford JM, Bird ET, Yandell PM. Postoperative prophylactic antibiotics for retropubic mid-urethral slings. Int Urogynecol J. 2022 04; 33(4):897-902.
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Franciosi EB, Amano SU, Scharf MJ. Porphyria cutanea tarda associated with nitrofurantoin: A unique drug reaction. Dermatol Ther. 2020 11; 33(6):e14026.
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Hanley RS, Stoffel JT, Zagha RM, Mourtzinos A, Bresette JF. Multimodal therapy for painful bladder syndrome / interstitial cystitis: pilot study combining behavioral, pharmacologic, and endoscopic therapies. Int Braz J Urol. 2009 Jul-Aug; 35(4):467-74.
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Peedikayil MC, Dahhan TI, Al Ashgar HI. Nitrofurantoin-induced fulminant hepatitis mimicking autoimmune hepatitis. Ann Pharmacother. 2006 Oct; 40(10):1888-9.
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Liesching T, O'Brien A. Dyspnea, chest pain, and cough: the lurking culprit. Nitrofurantoin-induced pulmonary toxicity. Postgrad Med. 2002 Jul; 112(1):19-20, 24.
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Dershwitz M, Ts'ao CH, Novak RF. Metabolic and morphologic effects of the antimicrobial agent nitrofurantoin on human erythrocytes in vitro. Biochem Pharmacol. 1985 Jun 01; 34(11):1963-70.
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Dershwitz M, Novak RF. Studies on the mechanism of nitrofurantoin-mediated red cell toxicity. J Pharmacol Exp Ther. 1982 Aug; 222(2):430-4.
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Dershwitz M, Novak RF. Generation of superoxide via the interaction of nitrofurantoin with oxyhemoglobin. J Biol Chem. 1982 Jan 10; 257(1):75-9.
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Dershwitz M, Novak RF. Lack of inhibition of glutathione reductase by unnitrated derivatives of nitrofurantoin. Biochem Biophys Res Commun. 1980 Feb 27; 92(4):1313-9.