"Desipramine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors.
Descriptor ID |
D003891
|
MeSH Number(s) |
D03.633.300.240.281
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Concept/Terms |
Desipramine- Desipramine
- Desmethylimipramine
- Demethylimipramine
|
Below are MeSH descriptors whose meaning is more general than "Desipramine".
Below are MeSH descriptors whose meaning is more specific than "Desipramine".
This graph shows the total number of publications written about "Desipramine" by people in this website by year, and whether "Desipramine" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1999 | 2 | 0 | 2 |
2002 | 0 | 1 | 1 |
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Below are the most recent publications written about "Desipramine" by people in Profiles.
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King JA, Messenger T, Ferris CF. Seed finding in golden hamsters: a potential animal model for screening anxiolytic drugs. Neuropsychobiology. 2002; 45(3):150-5.
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Walsh BT, Greenhill LL, Giardina EG, Bigger JT, Waslick BD, Sloan RP, Bilich K, Wolk S, Bagiella E. Effects of desipramine on autonomic input to the heart. J Am Acad Child Adolesc Psychiatry. 1999 Sep; 38(9):1186-92.
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Waslick BD, Walsh BT, Greenhill LL, Giardina EG, Sloan RP, Bigger JT, Bilich K. Cardiovascular effects of desipramine in children and adults during exercise testing. J Am Acad Child Adolesc Psychiatry. 1999 Feb; 38(2):179-86.
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Steingard RJ, DeMaso DR, Goldman SJ, Shorrock KL, Bucci JP. Current perspectives on the pharmacotherapy of depressive disorders in children and adolescents. Harv Rev Psychiatry. 1995 Mar-Apr; 2(6):313-26.
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Semrud-Clikeman M, Filipek PA, Biederman J, Steingard R, Kennedy D, Renshaw P, Bekken K. Attention-deficit hyperactivity disorder: magnetic resonance imaging morphometric analysis of the corpus callosum. J Am Acad Child Adolesc Psychiatry. 1994 Jul-Aug; 33(6):875-81.
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Spencer T, Biederman J, Kerman K, Steingard R, Wilens T. Desipramine treatment of children with attention-deficit hyperactivity disorder and tic disorder or Tourette's syndrome. J Am Acad Child Adolesc Psychiatry. 1993 Mar; 32(2):354-60.
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Spencer T, Biederman J, Steingard R, Wilens T. Bupropion exacerbates tics in children with attention-deficit hyperactivity disorder and Tourette's syndrome. J Am Acad Child Adolesc Psychiatry. 1993 Jan; 32(1):211-4.