Leucovorin

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"Leucovorin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The active metabolite of FOLIC ACID. Leucovorin is used principally as an antidote to FOLIC ACID ANTAGONISTS.

Descriptor ID	D002955
MeSH Number(s)	D03.633.100.733.631.400.800.350.450 D08.211.840.300.500
Concept/Terms	Leucovorin Leucovorin Folinic Acid-SF Folinic Acid SF Leukovorin Leukovorum Folinic Acid Acid, Folinic Leucovorin, (DL)-Isomer Leucovorin, (DL)-Isomer Citrovorum Factor Citrovorum Factor Factor, Citrovorum Calcium Leucovorin Leucovorin, Calcium Calcium Folinate Folinate, Calcium Leucovorin, (R)-Isomer Leucovorin, (R)-Isomer Leucovorin, Calcium (1:1) Salt Leucovorin, Calcium (1:1) Salt Leucovorin, Calcium (1:1) Salt, Pentahydrate Leucovorin, Calcium (1:1) Salt, Pentahydrate Leucovorin, Monosodium Salt Leucovorin, Monosodium Salt Monosodium Salt Leucovorin N(5)-Formyltetrahydrofolate N(5)-Formyltetrahydrofolate 5-Formyltetrahydropteroylglutamate 5 Formyltetrahydropteroylglutamate 5-Formyltetrahydrofolate 5 Formyltetrahydrofolate Wellcovorin Wellcovorin Leucovorin, (D)-Isomer Leucovorin, (D)-Isomer Leucovorin, Calcium (1:1) Salt, (DL)-Isomer Leucovorin, Calcium (1:1) Salt, (DL)-Isomer

Below are MeSH descriptors whose meaning is more general than "Leucovorin".

Chemicals and Drugs [D]
Heterocyclic Compounds [D03]
Heterocyclic Compounds, Fused-Ring [D03.633]
Heterocyclic Compounds, 2-Ring [D03.633.100]
Pteridines [D03.633.100.733]
Pterins [D03.633.100.733.631]
Folic Acid [D03.633.100.733.631.400]
Tetrahydrofolates [D03.633.100.733.631.400.800]
Formyltetrahydrofolates [D03.633.100.733.631.400.800.350]
Leucovorin [D03.633.100.733.631.400.800.350.450]
Enzymes and Coenzymes [D08]
Coenzymes [D08.211]
Tetrahydrofolates [D08.211.840]
Formyltetrahydrofolates [D08.211.840.300]
Leucovorin [D08.211.840.300.500]

Below are MeSH descriptors whose meaning is related to "Leucovorin".

Below are MeSH descriptors whose meaning is more specific than "Leucovorin".

Leucovorin
Levoleucovorin

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Leucovorin" by people in this website by year, and whether "Leucovorin" was a major or minor topic of these publications.

Bar chart showing 7 publications over 7 distinct years, with a maximum of 1 publications in 1996 and 1997 and 2008 and 2009 and 2011 and 2017 and 2021

To see the data from this visualization as text, click here.

Year	Minor Topic	Total
1996	1	1
1997	1	1
2008	1	1
2009	1	1
2011	1	1
2017	1	1
2021	1	1

Below are the most recent publications written about "Leucovorin" by people in Profiles.

Jones O, Cheng X, Murthy SRK, Ly L, Zhuang T, Basadonna G, Keidar M, Canady J. The synergistic effect of Canady Helios cold atmospheric plasma and a FOLFIRINOX regimen for the treatment of cholangiocarcinoma in vitro. Sci Rep. 2021 04 26; 11(1):8967.

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Fuchs CS, Niedzwiecki D, Mamon HJ, Tepper JE, Ye X, Swanson RS, Enzinger PC, Haller DG, Dragovich T, Alberts SR, Bjarnason GA, Willett CG, Gunderson LL, Goldberg RM, Venook AP, Ilson D, O'Reilly E, Ciombor K, Berg DJ, Meyerhardt J, Mayer RJ. Adjuvant Chemoradiotherapy With Epirubicin, Cisplatin, and Fluorouracil Compared With Adjuvant Chemoradiotherapy With Fluorouracil and Leucovorin After Curative Resection of Gastric Cancer: Results From CALGB 80101 (Alliance). J Clin Oncol. 2017 Nov 10; 35(32):3671-3677.

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Due?as-Garcia OF, Young C. Heterotopic cesarean scar pregnancy associated with a levonorgestrel-releasing intrauterine device. Int J Gynaecol Obstet. 2011 Aug; 114(2):153-4.

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Hesketh PJ, Sanz-Altamira P, Bushey J, Hesketh AM. Prospective evaluation of the incidence of delayed nausea and vomiting in patients with colorectal cancer receiving oxaliplatin-based chemotherapy. Support Care Cancer. 2012 May; 20(5):1043-7.

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Cerny J, Hassan A, Smith C, Piperdi B. Coronary vasospasm with myocardial stunning in a patient with colon cancer receiving adjuvant chemotherapy with FOLFOX regimen. Clin Colorectal Cancer. 2009 Jan; 8(1):55-8.

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Gammon DC, Bhatt MS, Patel B, Anderson M, Van Horn A, Glantz MJ. Managing reduced methotrexate clearance in a patient with a heterozygous methylenetetrahydrofolate reductase gene polymorphism. J Oncol Pharm Pract. 2008 Sep; 14(3):153-6.

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Crookes P, Leichman CG, Leichman L, Tan M, Laine L, Stain S, Baranda J, Casagrande Y, Groshen S, Silberman H. Systemic chemotherapy for gastric carcinoma followed by postoperative intraperitoneal therapy: a final report. Cancer. 1997 May 01; 79(9):1767-75.

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Levine AM, Tulpule A, Espina B, Boswell W, Buckley J, Rasheed S, Stain S, Parker J, Nathwani B, Gill PS. Low dose methotrexate, bleomycin, doxorubicin, cyclophosphamide, vincristine, and dexamethasone with zalcitabine in patients with acquired immunodeficiency syndrome-related lymphoma. Effect on human immunodeficiency virus and serum interleukin-6 levels over time. Cancer. 1996 Aug 01; 78(3):517-26.

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Leichman L, Silberman H, Leichman CG, Spears CP, Ray M, Muggia FM, Kiyabu M, Radin R, Laine L, Stain S, et al. Preoperative systemic chemotherapy followed by adjuvant postoperative intraperitoneal therapy for gastric cancer: a University of Southern California pilot program. J Clin Oncol. 1992 Dec; 10(12):1933-42.

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Hesketh PJ, Bulger KN. Role of adjuvant therapy in colorectal cancer. Adv Intern Med. 1991; 36:219-47.

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