"Papaverine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
| Descriptor ID |
D010208
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| MeSH Number(s) |
D03.132.098.666 D03.132.577.750 D03.633.100.531.085.666
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Papaverine".
Below are MeSH descriptors whose meaning is more specific than "Papaverine".
This graph shows the total number of publications written about "Papaverine" by people in this website by year, and whether "Papaverine" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
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Below are the most recent publications written about "Papaverine" by people in Profiles.
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Farb MG, Ganley-Leal L, Mott M, Liang Y, Ercan B, Widlansky ME, Bigornia SJ, Fiscale AJ, Apovian CM, Carmine B, Hess DT, Vita JA, Gokce N. Arteriolar function in visceral adipose tissue is impaired in human obesity. Arterioscler Thromb Vasc Biol. 2012 Feb; 32(2):467-73.
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Kopechek JA, Abruzzo TM, Wang B, Chrzanowski SM, Smith DA, Kee PH, Huang S, Collier JH, McPherson DD, Holland CK. Ultrasound-mediated release of hydrophilic and lipophilic agents from echogenic liposomes. J Ultrasound Med. 2008 Nov; 27(11):1597-606.
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Pennings FA, Albrecht KW, Muizelaar JP, Schuurman PR, Bouma GJ. Abnormal responses of the human cerebral microcirculation to papaverin during aneurysm surgery. Stroke. 2009 Jan; 40(1):317-20.
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Copel L, Katz R, Blachar A, Sosna J, Sheiman RG. Clinical and duplex US assessment of effects of sildenafil on cavernosal arteries of the penis: comparison with intracavernosal injection of vasoactive agents--initial experience. Radiology. 2005 Dec; 237(3):986-91.
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Fearon WF, Aarnoudse W, Pijls NH, De Bruyne B, Balsam LB, Cooke DT, Robbins RC, Fitzgerald PJ, Yeung AC, Yock PG. Microvascular resistance is not influenced by epicardial coronary artery stenosis severity: experimental validation. Circulation. 2004 May 18; 109(19):2269-72.
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Fearon WF, Farouque HM, Balsam LB, Caffarelli AD, Cooke DT, Robbins RC, Fitzgerald PJ, Yeung AC, Yock PG. Comparison of coronary thermodilution and Doppler velocity for assessing coronary flow reserve. Circulation. 2003 Nov 04; 108(18):2198-200.
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Williams G, Mulcahy MJ, Hartnell G, Kiely E. Diagnosis and treatment of venous leakage: a curable cause of impotence. Br J Urol. 1988 Feb; 61(2):151-5.