Anthelmintics

"Anthelmintics" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Agents destructive to parasitic worms. They are used therapeutically in the treatment of HELMINTHIASIS in man and animal.

Descriptor ID	D000871
MeSH Number(s)	D27.505.954.122.250.075
Concept/Terms	Anthelmintics Anthelmintics Antihelmintics Vermifuges

Below are MeSH descriptors whose meaning is more general than "Anthelmintics".

Chemicals and Drugs [D]
Chemical Actions and Uses [D27]
Pharmacologic Actions [D27.505]
Therapeutic Uses [D27.505.954]
Anti-Infective Agents [D27.505.954.122]
Antiparasitic Agents [D27.505.954.122.250]
Anthelmintics [D27.505.954.122.250.075]

Below are MeSH descriptors whose meaning is related to "Anthelmintics".

Below are MeSH descriptors whose meaning is more specific than "Anthelmintics".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Anthelmintics" by people in this website by year, and whether "Anthelmintics" was a major or minor topic of these publications.

Bar chart showing 32 publications over 16 distinct years, with a maximum of 4 publications in 2024

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	0	1	1
2007	0	1	1
2009	1	0	1
2010	2	0	2
2012	2	0	2
2013	2	0	2
2014	1	0	1
2015	1	0	1
2018	3	0	3
2019	1	2	3
2020	3	0	3
2021	2	0	2
2022	1	0	1
2023	2	0	2
2024	2	2	4
2025	3	0	3

Below are the most recent publications written about "Anthelmintics" by people in Profiles.

D'Almeida RE, Chen P, Huang Y, Goetz E, Sammeta VR, Yang B, Rao RP, Rasapalli S, Elfawal MA. Design, synthesis, and biological evaluation of a focused pyrrolo- and pyrido-quinazolinone natural products-templated library for anti-fungal and anthelmintic activities. Bioorg Med Chem. 2026 Mar; 134:118517.

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Elfawal MA, Banas V, Rosa BA, Mahoney M, Goetz E, Chen P, Aroian RV, Janetka JW, Mitreva M. Anthelmintics Derived from the Kinase Inhibitor SGI-1776 for the Treatment of Gastrointestinal Worm Infections. ACS Infect Dis. 2025 Nov 14; 11(11):3196-3211.

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Banas V, Elfawal MA, Rosa BA, Mahoney M, Kauffman J, Goetz E, Chen P, Aroian RV, Mitreva M, Janetka JW. Discovery of Human PIM Kinase Inhibitors as a Class of Anthelmintic Drugs to Treat Intestinal Nematode Infections. ACS Infect Dis. 2025 Feb 14; 11(2):506-517.

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Elfawal MA, Goetz E, Kim Y, Chen P, Savinov SN, Barasa L, Thompson PR, Aroian RV. High-Throughput Screening of More Than 30,000 Compounds for Anthelmintics against Gastrointestinal Nematode Parasites. ACS Infect Dis. 2025 Jan 10; 11(1):104-120.

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Hoang D, Flanagan K, Ding Q, Cazeault NR, Li H, D?az-Valerio S, Rus F, Darfour EA, Kass E, Petersson KH, Nielsen MK, Liesegang H, Ostroff GR, Aroian RV. Bacillus thuringiensis Cry14A family proteins as novel anthelmintics against gastrointestinal nematode parasites. PLoS Negl Trop Dis. 2024 Oct; 18(10):e0012611.

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Means AR, ?sbj?rnsd?ttir KH, Sharrock KC, Galagan SR, Aruldas K, Avokpaho E, Chabi F, Halliday KE, Houngbegnon P, Israel GJ, Kaliappan SP, Kennedy D, Legge H, Oswald WE, Palanisamy G, Rogers E, Timothy J, Pearman E, Ramesh RM, Simwanza J, Sheik-Abdullah JF, Sheikh M, Togbevi CI, Witek-McManus S, Pullan RL, Bailey R, Kalua K, Ibikounl? M, Luty AJF, Ajjampur SSR, Walson JL. Coverage of community-wide mass drug administration platforms for soil-transmitted helminths in Benin, India, and Malawi: findings from the DeWorm3 project. Infect Dis Poverty. 2024 Oct 08; 13(1):72.

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Williams PDE, Brewer MT, Aroian RV, Robertson AP, Martin RJ. The nematode (Ascaris suum) intestine is a location of synergistic anthelmintic effects of Cry5B and levamisole. PLoS Pathog. 2024 May; 20(5):e1011835.

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Aroian RV, Loukas A, Martin RJ. Anthelmintics V: Drugs, resistance, and vaccines. Int J Parasitol. 2023 07; 53(8):391-392.

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Shaver AO, Wit J, Dilks CM, Crombie TA, Li H, Aroian RV, Andersen EC. Variation in anthelmintic responses are driven by genetic differences among diverse C. elegans wild strains. PLoS Pathog. 2023 04; 19(4):e1011285.

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Chicca J, Cazeault NR, Rus F, Abraham A, Garceau C, Li H, Atwa SM, Flanagan K, Soto ER, Morrison MS, Gazzola D, Hu Y, Liu DR, Nielsen MK, Urban JF, Ostroff GR, Aroian RV. Efficient and Scalable Process to Produce Novel and Highly Bioactive Purified Cytosolic Crystals from Bacillus thuringiensis. Microbiol Spectr. 2022 08 31; 10(4):e0235622.

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