Dehydroepiandrosterone

"Dehydroepiandrosterone" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.

Descriptor ID	D003687
MeSH Number(s)	D04.210.500.054.079.429.625 D04.210.500.578.502.400 D06.472.040.502.400 D06.472.334.851.968.952
Concept/Terms	Dehydroepiandrosterone Dehydroepiandrosterone 5-Androsten-3-beta-hydroxy-17-one 5 Androsten 3 beta hydroxy 17 one DHEA Prasterone Androstenolone Dehydroisoandrosterone Prasterone, 3 alpha-Isomer Prasterone, 3 alpha-Isomer Prasterone, 3 alpha Isomer 5-Androsten-3-ol-17-one 5-Androsten-3-ol-17-one 5 Androsten 3 ol 17 one

Below are MeSH descriptors whose meaning is more general than "Dehydroepiandrosterone".

Chemicals and Drugs [D]
Polycyclic Compounds [D04]
Fused-Ring Compounds [D04.210]
Steroids [D04.210.500]
Androstanes [D04.210.500.054]
Androstenes [D04.210.500.054.079]
Androstenols [D04.210.500.054.079.429]
Dehydroepiandrosterone [D04.210.500.054.079.429.625]
Ketosteroids [D04.210.500.578]
17-Ketosteroids [D04.210.500.578.502]
Dehydroepiandrosterone [D04.210.500.578.502.400]
Hormones, Hormone Substitutes, and Hormone Antagonists [D06]
Hormones [D06.472]
Adrenal Cortex Hormones [D06.472.040]
17-Ketosteroids [D06.472.040.502]
Dehydroepiandrosterone [D06.472.040.502.400]
Gonadal Hormones [D06.472.334]
Gonadal Steroid Hormones [D06.472.334.851]
Testosterone Congeners [D06.472.334.851.968]
Dehydroepiandrosterone [D06.472.334.851.968.952]

Below are MeSH descriptors whose meaning is related to "Dehydroepiandrosterone".

Below are MeSH descriptors whose meaning is more specific than "Dehydroepiandrosterone".

Dehydroepiandrosterone
Dehydroepiandrosterone Sulfate

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Dehydroepiandrosterone" by people in this website by year, and whether "Dehydroepiandrosterone" was a major or minor topic of these publications.

Bar chart showing 12 publications over 9 distinct years, with a maximum of 2 publications in 2002 and 2003 and 2009

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1999	1	0	1
2001	1	0	1
2002	2	0	2
2003	1	1	2
2009	1	1	2
2011	0	1	1
2012	0	1	1
2013	1	0	1
2018	1	0	1

Below are the most recent publications written about "Dehydroepiandrosterone" by people in Profiles.

Doan SN, DeYoung G, Fuller-Rowell TE, Liu C, Meyer J. Investigating relations among stress, sleep and nail cortisol and DHEA. Stress. 2018 03; 21(2):188-193.

View in: PubMed
Lasley BL, Crawford SL, McConnell DS. Ovarian adrenal interactions during the menopausal transition. Minerva Ginecol. 2013 Dec; 65(6):641-51.

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Lasley BL, Chen J, Stanczyk FZ, El Khoudary SR, Gee NA, Crawford S, McConnell DS. Androstenediol complements estrogenic bioactivity during the menopausal transition. Menopause. 2012 Jun; 19(6):650-7.

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Cai C, Chen S, Ng P, Bubley GJ, Nelson PS, Mostaghel EA, Marck B, Matsumoto AM, Simon NI, Wang H, Chen S, Balk SP. Intratumoral de novo steroid synthesis activates androgen receptor in castration-resistant prostate cancer and is upregulated by treatment with CYP17A1 inhibitors. Cancer Res. 2011 Oct 15; 71(20):6503-13.

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Kushnir MM, Blamires T, Rockwood AL, Roberts WL, Yue B, Erdogan E, Bunker AM, Meikle AW. Liquid chromatography-tandem mass spectrometry assay for androstenedione, dehydroepiandrosterone, and testosterone with pediatric and adult reference intervals. Clin Chem. 2010 Jul; 56(7):1138-47.

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Koutsari C, Ali AH, Nair KS, Rizza RA, O'Brien P, Khosla S, Jensen MD. Fatty acid metabolism in the elderly: effects of dehydroepiandrosterone and testosterone replacement in hormonally deficient men and women. J Clin Endocrinol Metab. 2009 Sep; 94(9):3414-23.

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Crawford S, Santoro N, Laughlin GA, Sowers MF, McConnell D, Sutton-Tyrrell K, Weiss G, Vuga M, Randolph J, Lasley B. Circulating dehydroepiandrosterone sulfate concentrations during the menopausal transition. J Clin Endocrinol Metab. 2009 Aug; 94(8):2945-51.

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Yang R, Tibbs BM, Chang B, Nguyen C, Woodall C, Steppacher R, Helling T, Morrison DC, Van Way CW. Effect of DHEA on the hemodynamic response to resuscitation in a porcine model of hemorrhagic shock. J Trauma. 2006 Dec; 61(6):1343-9.

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Catalina F, Milewich L, Kumar V, Bennett M. Dietary dehydroepiandrosterone inhibits bone marrow and leukemia cell transplants: role of food restriction. Exp Biol Med (Maywood). 2003 Dec; 228(11):1303-20.

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Dorgan JF, Hunsberger SA, McMahon RP, Kwiterovich PO, Lauer RM, Van Horn L, Lasser NL, Stevens VJ, Friedman LA, Yanovski JA, Greenhut SF, Chandler DW, Franklin FA, Barton BA, Buckman DW, Snetselaar LG, Patterson BH, Schatzkin A, Taylor PR. Diet and sex hormones in girls: findings from a randomized controlled clinical trial. J Natl Cancer Inst. 2003 Jan 15; 95(2):132-41.

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