Azacitidine

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"Azacitidine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A pyrimidine analogue that inhibits DNA methyltransferase, impairing DNA methylation. It is also an antimetabolite of cytidine, incorporated primarily into RNA. Azacytidine has been used as an antineoplastic agent.

Descriptor ID	D001374
MeSH Number(s)	D02.145.150 D03.383.742.680.245.217 D13.570.685.245.217 D13.570.800.286.300
Concept/Terms	Azacitidine Azacitidine 5-Azacytidine 5 Azacytidine Azacytidine Vidaza Vidaza NSC-102816 NSC-102816 NSC 102816 NSC102816

Below are MeSH descriptors whose meaning is more general than "Azacitidine".

Chemicals and Drugs [D]
Organic Chemicals [D02]
Aza Compounds [D02.145]
Azacitidine [D02.145.150]
Heterocyclic Compounds [D03]
Heterocyclic Compounds, 1-Ring [D03.383]
Pyrimidines [D03.383.742]
Pyrimidine Nucleosides [D03.383.742.680]
Cytidine [D03.383.742.680.245]
Azacitidine [D03.383.742.680.245.217]
Nucleic Acids, Nucleotides, and Nucleosides [D13]
Nucleosides [D13.570]
Pyrimidine Nucleosides [D13.570.685]
Cytidine [D13.570.685.245]
Azacitidine [D13.570.685.245.217]
Ribonucleosides [D13.570.800]
Cytidine [D13.570.800.286]
Azacitidine [D13.570.800.286.300]

Below are MeSH descriptors whose meaning is related to "Azacitidine".

Below are MeSH descriptors whose meaning is more specific than "Azacitidine".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Azacitidine" by people in this website by year, and whether "Azacitidine" was a major or minor topic of these publications.

Bar chart showing 11 publications over 8 distinct years, with a maximum of 2 publications in 2005 and 2013 and 2020

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	1	0	1
2005	1	1	2
2006	0	1	1
2013	0	2	2
2015	0	1	1
2017	1	0	1
2018	1	0	1
2020	0	2	2

Below are the most recent publications written about "Azacitidine" by people in Profiles.

Ghandili S, Pfefferle S, Roedl K, Sonnemann P, Karagiannis P, Boenisch O, Kluge S, Schmiedel S, Ittrich H, Rohde H, L?tgehetmann M, Weisel K, Bokemeyer C, Wichmann D, Fiedler W, Jarczak D, Modemann F. Challenges in treatment of patients with acute leukemia and COVID-19: a series of 12 patients. Blood Adv. 2020 12 08; 4(23):5936-5941.

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Azizi A, Ediriwickrema A, Dutta R, Patel SA, Shomali W, Medeiros B, Iberri D, Gotlib J, Mannis G, Greenberg P, Majeti R, Zhang T. Venetoclax and hypomethylating agent therapy in high risk myelodysplastic syndromes: a retrospective evaluation of a real-world experience. Leuk Lymphoma. 2020 11; 61(11):2700-2707.

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Sandberg DI, Yu B, Patel R, Hagan J, Miesner E, Sabin J, Smith S, Fletcher S, Shah MN, Sirianni RW, Taylor MD. Infusion of 5-Azacytidine (5-AZA) into the fourth ventricle or resection cavity in children with recurrent posterior Fossa Ependymoma: a pilot clinical trial. J Neurooncol. 2019 Jan; 141(2):449-457.

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Varanasi SK, Reddy PBJ, Bhela S, Jaggi U, Gimenez F, Rouse BT. Azacytidine Treatment Inhibits the Progression of Herpes Stromal Keratitis by Enhancing Regulatory T Cell Function. J Virol. 2017 04 01; 91(7).

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Desai N, Sajed D, Arora KS, Solovyov A, Rajurkar M, Bledsoe JR, Sil S, Amri R, Tai E, MacKenzie OC, Mino-Kenudson M, Aryee MJ, Ferrone CR, Berger DL, Rivera MN, Greenbaum BD, Deshpande V, Ting DT. Diverse repetitive element RNA expression defines epigenetic and immunologic features of colon cancer. JCI Insight. 2017 02 09; 2(3):e91078.

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Chen X, Liu L, Mims J, Punska EC, Williams KE, Zhao W, Arcaro KF, Tsang AW, Zhou X, Furdui CM. Analysis of DNA methylation and gene expression in radiation-resistant head and neck tumors. Epigenetics. 2015; 10(6):545-61.

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Williams KE, Anderton DL, Lee MP, Pentecost BT, Arcaro KF. High-density array analysis of DNA methylation in Tamoxifen-resistant breast cancer cell lines. Epigenetics. 2014 Feb; 9(2):297-307.

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Sagransky MJ, Deng AC, Magro CM. Primary cutaneous langerhans cell sarcoma: a report of four cases and review of the literature. Am J Dermatopathol. 2013 Apr; 35(2):196-204.

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Mao W, Rubin JS, Anoruo N, Wordinger RJ, Clark AF. SFRP1 promoter methylation and expression in human trabecular meshwork cells. Exp Eye Res. 2012 Apr; 97(1):130-6.

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Cheng YY, Yu J, Wong YP, Man EP, To KF, Jin VX, Li J, Tao Q, Sung JJ, Chan FK, Leung WK. Frequent epigenetic inactivation of secreted frizzled-related protein 2 (SFRP2) by promoter methylation in human gastric cancer. Br J Cancer. 2007 Oct 08; 97(7):895-901.

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