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Connection

Melissa Moore to RNA Splicing

This is a "connection" page, showing publications Melissa Moore has written about RNA Splicing.
Connection Strength

6.457
  1. Braun JE, Friedman LJ, Gelles J, Moore MJ. Synergistic assembly of human pre-spliceosomes across introns and exons. Elife. 2018 06 22; 7.
    View in: PubMed
    Score: 0.546
  2. Hoskins AA, Rodgers ML, Friedman LJ, Gelles J, Moore MJ. Single molecule analysis reveals reversible and irreversible steps during spliceosome activation. Elife. 2016 05 31; 5.
    View in: PubMed
    Score: 0.474
  3. Chen W, Moore MJ. The spliceosome: disorder and dynamics defined. Curr Opin Struct Biol. 2014 Feb; 24:141-9.
    View in: PubMed
    Score: 0.404
  4. Chen W, Shulha HP, Ashar-Patel A, Yan J, Green KM, Query CC, Rhind N, Weng Z, Moore MJ. Endogenous U2?U5?U6 snRNA complexes in S. pombe are intron lariat spliceosomes. RNA. 2014 Mar; 20(3):308-20.
    View in: PubMed
    Score: 0.402
  5. Crawford DJ, Hoskins AA, Friedman LJ, Gelles J, Moore MJ. Single-molecule colocalization FRET evidence that spliceosome activation precedes stable approach of 5' splice site and branch site. Proc Natl Acad Sci U S A. 2013 Apr 23; 110(17):6783-8.
    View in: PubMed
    Score: 0.381
  6. Hoskins AA, Moore MJ. The spliceosome: a flexible, reversible macromolecular machine. Trends Biochem Sci. 2012 May; 37(5):179-88.
    View in: PubMed
    Score: 0.355
  7. Hoskins AA, Gelles J, Moore MJ. New insights into the spliceosome by single molecule fluorescence microscopy. Curr Opin Chem Biol. 2011 Dec; 15(6):864-70.
    View in: PubMed
    Score: 0.345
  8. Hoskins AA, Friedman LJ, Gallagher SS, Crawford DJ, Anderson EG, Wombacher R, Ramirez N, Cornish VW, Gelles J, Moore MJ. Ordered and dynamic assembly of single spliceosomes. Science. 2011 Mar 11; 331(6022):1289-95.
    View in: PubMed
    Score: 0.330
  9. O'Brien K, Matlin AJ, Lowell AM, Moore MJ. The biflavonoid isoginkgetin is a general inhibitor of Pre-mRNA splicing. J Biol Chem. 2008 Nov 28; 283(48):33147-54.
    View in: PubMed
    Score: 0.278
  10. Crawford DJ, Hoskins AA, Friedman LJ, Gelles J, Moore MJ. Visualizing the splicing of single pre-mRNA molecules in whole cell extract. RNA. 2008 Jan; 14(1):170-9.
    View in: PubMed
    Score: 0.262
  11. Matlin AJ, Moore MJ. Spliceosome assembly and composition. Adv Exp Med Biol. 2007; 623:14-35.
    View in: PubMed
    Score: 0.247
  12. Tange T?, Shibuya T, Jurica MS, Moore MJ. Biochemical analysis of the EJC reveals two new factors and a stable tetrameric protein core. RNA. 2005 Dec; 11(12):1869-83.
    View in: PubMed
    Score: 0.229
  13. Tange T?, Nott A, Moore MJ. The ever-increasing complexities of the exon junction complex. Curr Opin Cell Biol. 2004 Jun; 16(3):279-84.
    View in: PubMed
    Score: 0.206
  14. Shibuya T, Tange T?, Sonenberg N, Moore MJ. eIF4AIII binds spliced mRNA in the exon junction complex and is essential for nonsense-mediated decay. Nat Struct Mol Biol. 2004 Apr; 11(4):346-51.
    View in: PubMed
    Score: 0.203
  15. Nott A, Le Hir H, Moore MJ. Splicing enhances translation in mammalian cells: an additional function of the exon junction complex. Genes Dev. 2004 Jan 15; 18(2):210-22.
    View in: PubMed
    Score: 0.201
  16. Jurica MS, Moore MJ. Pre-mRNA splicing: awash in a sea of proteins. Mol Cell. 2003 Jul; 12(1):5-14.
    View in: PubMed
    Score: 0.194
  17. Le Hir H, Nott A, Moore MJ. How introns influence and enhance eukaryotic gene expression. Trends Biochem Sci. 2003 Apr; 28(4):215-20.
    View in: PubMed
    Score: 0.190
  18. Reichert VL, Le Hir H, Jurica MS, Moore MJ. 5' exon interactions within the human spliceosome establish a framework for exon junction complex structure and assembly. Genes Dev. 2002 Nov 01; 16(21):2778-91.
    View in: PubMed
    Score: 0.185
  19. Jurica MS, Moore MJ. Capturing splicing complexes to study structure and mechanism. Methods. 2002 Nov; 28(3):336-45.
    View in: PubMed
    Score: 0.185
  20. Metkar M, Ozadam H, Lajoie BR, Imakaev M, Mirny LA, Dekker J, Moore MJ. Higher-Order Organization Principles of Pre-translational mRNPs. Mol Cell. 2018 11 15; 72(4):715-726.e3.
    View in: PubMed
    Score: 0.140
  21. Chen W, Moore J, Ozadam H, Shulha HP, Rhind N, Weng Z, Moore MJ. Transcriptome-wide Interrogation of the Functional Intronome by Spliceosome Profiling. Cell. 2018 05 03; 173(4):1031-1044.e13.
    View in: PubMed
    Score: 0.135
  22. Singh G, Pratt G, Yeo GW, Moore MJ. The Clothes Make the mRNA: Past and Present Trends in mRNP Fashion. Annu Rev Biochem. 2015; 84:325-54.
    View in: PubMed
    Score: 0.109
  23. Shcherbakova I, Hoskins AA, Friedman LJ, Serebrov V, Corr?a IR, Xu MQ, Gelles J, Moore MJ. Alternative spliceosome assembly pathways revealed by single-molecule fluorescence microscopy. Cell Rep. 2013 Oct 17; 5(1):151-65.
    View in: PubMed
    Score: 0.098
  24. Singh G, Kucukural A, Cenik C, Leszyk JD, Shaffer SA, Weng Z, Moore MJ. The cellular EJC interactome reveals higher-order mRNP structure and an EJC-SR protein nexus. Cell. 2012 Nov 09; 151(4):750-764.
    View in: PubMed
    Score: 0.092
  25. Albert BJ, McPherson PA, O'Brien K, Czaicki NL, Destefino V, Osman S, Li M, Day BW, Grabowski PJ, Moore MJ, Vogt A, Koide K. Meayamycin inhibits pre-messenger RNA splicing and exhibits picomolar activity against multidrug-resistant cells. Mol Cancer Ther. 2009 Aug; 8(8):2308-18.
    View in: PubMed
    Score: 0.074
  26. Shibuya T, Tange T?, Stroupe ME, Moore MJ. Mutational analysis of human eIF4AIII identifies regions necessary for exon junction complex formation and nonsense-mediated mRNA decay. RNA. 2006 Mar; 12(3):360-74.
    View in: PubMed
    Score: 0.058
  27. Nott A, Meislin SH, Moore MJ. A quantitative analysis of intron effects on mammalian gene expression. RNA. 2003 May; 9(5):607-17.
    View in: PubMed
    Score: 0.048
  28. Jurica MS, Licklider LJ, Gygi SR, Grigorieff N, Moore MJ. Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis. RNA. 2002 Apr; 8(4):426-39.
    View in: PubMed
    Score: 0.044
  29. Cenik C, Chua HN, Zhang H, Tarnawsky SP, Akef A, Derti A, Tasan M, Moore MJ, Palazzo AF, Roth FP. Genome analysis reveals interplay between 5'UTR introns and nuclear mRNA export for secretory and mitochondrial genes. PLoS Genet. 2011 Apr; 7(4):e1001366.
    View in: PubMed
    Score: 0.021
  30. Lemmens R, Moore MJ, Al-Chalabi A, Brown RH, Robberecht W. RNA metabolism and the pathogenesis of motor neuron diseases. Trends Neurosci. 2010 May; 33(5):249-58.
    View in: PubMed
    Score: 0.019
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.