Susan Swain to Aging
This is a "connection" page, showing publications Susan Swain has written about Aging.
Connection Strength
4.341
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Swain SL, Kugler-Umana O, Kuang Y, Zhang W. The properties of the unique age-associated B cell subset reveal a shift in strategy of immune response with age. Cell Immunol. 2017 Nov; 321:52-60.
Score: 0.382
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Brahmakshatriya V, Kuang Y, Devarajan P, Xia J, Zhang W, Vong AM, Swain SL. IL-6 Production by TLR-Activated APC Broadly Enhances Aged Cognate CD4 Helper and B Cell Antibody Responses In Vivo. J Immunol. 2017 04 01; 198(7):2819-2833.
Score: 0.373
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Zhang W, Brahmakshatriya V, Swain SL. CD4 T cell defects in the aged: causes, consequences and strategies to circumvent. Exp Gerontol. 2014 Jun; 54:67-70.
Score: 0.300
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Swain SL, Blomberg BB. Immune senescence: new insights into defects but continued mystery of root causes. Curr Opin Immunol. 2013 Aug; 25(4):495-7.
Score: 0.292
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Haynes L, Swain SL. Aged-related shifts in T cell homeostasis lead to intrinsic T cell defects. Semin Immunol. 2012 Oct; 24(5):350-5.
Score: 0.267
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Tsukamoto H, Huston GE, Dibble J, Duso DK, Swain SL. Bim dictates naive CD4 T cell lifespan and the development of age-associated functional defects. J Immunol. 2010 Oct 15; 185(8):4535-44.
Score: 0.238
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Tsukamoto H, Clise-Dwyer K, Huston GE, Duso DK, Buck AL, Johnson LL, Haynes L, Swain SL. Age-associated increase in lifespan of naive CD4 T cells contributes to T-cell homeostasis but facilitates development of functional defects. Proc Natl Acad Sci U S A. 2009 Oct 27; 106(43):18333-8.
Score: 0.223
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Dorshkind K, Swain S. Age-associated declines in immune system development and function: causes, consequences, and reversal. Curr Opin Immunol. 2009 Aug; 21(4):404-7.
Score: 0.220
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Swain SL, Nikolich-Zugich J. Key research opportunities in immune system aging. J Gerontol A Biol Sci Med Sci. 2009 Feb; 64(2):183-6.
Score: 0.214
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Clise-Dwyer K, Huston GE, Buck AL, Duso DK, Swain SL. Environmental and intrinsic factors lead to antigen unresponsiveness in CD4(+) recent thymic emigrants from aged mice. J Immunol. 2007 Feb 01; 178(3):1321-31.
Score: 0.185
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Haynes L, Swain SL. Why aging T cells fail: implications for vaccination. Immunity. 2006 Jun; 24(6):663-666.
Score: 0.177
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Swain S, Clise-Dwyer K, Haynes L. Homeostasis and the age-associated defect of CD4 T cells. Semin Immunol. 2005 Oct; 17(5):370-7.
Score: 0.169
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Haynes L, Eaton SM, Burns EM, Randall TD, Swain SL. Newly generated CD4 T cells in aged animals do not exhibit age-related defects in response to antigen. J Exp Med. 2005 Mar 21; 201(6):845-51.
Score: 0.163
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Haynes L, Eaton SM, Burns EM, Randall TD, Swain SL. CD4 T cell memory derived from young naive cells functions well into old age, but memory generated from aged naive cells functions poorly. Proc Natl Acad Sci U S A. 2003 Dec 09; 100(25):15053-8.
Score: 0.149
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Haynes L, Eaton SM, Swain SL. Effect of age on naive CD4 responses: impact on effector generation and memory development. Springer Semin Immunopathol. 2002; 24(1):53-60.
Score: 0.130
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Haynes L, Eaton SM, Swain SL. The defects in effector generation associated with aging can be reversed by addition of IL-2 but not other related gamma(c)-receptor binding cytokines. Vaccine. 2000 Feb 25; 18(16):1649-53.
Score: 0.115
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Kugler-Umana O, Devarajan P, Swain SL. Understanding the Heterogeneous Population of Age-Associated B Cells and Their Contributions to Autoimmunity and Immune Response to Pathogens. Crit Rev Immunol. 2020; 40(4):297-309.
Score: 0.113
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Haynes L, Linton PJ, Eaton SM, Tonkonogy SL, Swain SL. Interleukin 2, but not other common gamma chain-binding cytokines, can reverse the defect in generation of CD4 effector T cells from naive T cells of aged mice. J Exp Med. 1999 Oct 04; 190(7):1013-24.
Score: 0.111
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Haynes L, Linton PJ, Swain SL. Age-related changes in CD4 T cells of T cell receptor transgenic mice. Mech Ageing Dev. 1997 Feb; 93(1-3):95-105.
Score: 0.093
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Linton PJ, Haynes L, Klinman NR, Swain SL. Antigen-independent changes in naive CD4 T cells with aging. J Exp Med. 1996 Nov 01; 184(5):1891-900.
Score: 0.091
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Zhou X, Hopkins JW, Wang C, Brahmakshatriya V, Swain SL, Kuchel GA, Haynes L, McElhaney JE. IL-2 and IL-6 cooperate to enhance the generation of influenza-specific CD8 T cells responding to live influenza virus in aged mice and humans. Oncotarget. 2016 Jun 28; 7(26):39171-39183.
Score: 0.089
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Tsukamoto H, Senju S, Matsumura K, Swain SL, Nishimura Y. IL-6-mediated environmental conditioning of defective Th1 differentiation dampens antitumour immune responses in old age. Nat Commun. 2015 Apr 07; 6:6702.
Score: 0.082
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Eaton SM, Maue AC, Swain SL, Haynes L. Bone marrow precursor cells from aged mice generate CD4 T cells that function well in primary and memory responses. J Immunol. 2008 Oct 01; 181(7):4825-31.
Score: 0.052
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Haynes L, Swain SL, Cambier J, Fulder R. Aging and immune function. Summary of a workshop held at Trudeau Institute, Saranac Lake, NY. Mech Ageing Dev. 2005 Jun-Jul; 126(6-7):822-5.
Score: 0.041
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Haynes L, Eaton SM, Burns EM, Rincon M, Swain SL. Inflammatory cytokines overcome age-related defects in CD4 T cell responses in vivo. J Immunol. 2004 May 01; 172(9):5194-9.
Score: 0.038
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Rogerson BJ, Harris DP, Swain SL, Burgess DO. Germinal center B cells in Peyer's patches of aged mice exhibit a normal activation phenotype and highly mutated IgM genes. Mech Ageing Dev. 2003 Feb; 124(2):155-65.
Score: 0.035