Aging

"Aging" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Descriptor ID	D000375
MeSH Number(s)	G07.345.124
Concept/Terms	Aging Aging Senescence Senescence Biological Aging Biological Aging Aging, Biological

Below are MeSH descriptors whose meaning is more general than "Aging".

Biological Sciences [G]
Physiological Phenomena [G07]
Growth and Development [G07.345]
Aging [G07.345.124]

Below are MeSH descriptors whose meaning is related to "Aging".

Below are MeSH descriptors whose meaning is more specific than "Aging".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Aging" by people in this website by year, and whether "Aging" was a major or minor topic of these publications.

Bar chart showing 623 publications over 31 distinct years, with a maximum of 40 publications in 2017

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	6	2	8
1997	2	2	4
1998	4	5	9
1999	4	3	7
2000	5	5	10
2001	7	6	13
2002	10	8	18
2003	13	7	20
2004	8	8	16
2005	12	10	22
2006	9	14	23
2007	14	2	16
2008	11	9	20
2009	22	9	31
2010	13	7	20
2011	18	12	30
2012	20	7	27
2013	20	10	30
2014	20	5	25
2015	22	8	30
2016	23	12	35
2017	33	7	40
2018	17	5	22
2019	17	5	22
2020	20	11	31
2021	13	7	20
2022	1	18	19
2023	3	8	11
2024	9	11	20
2025	20	3	23
2026	1	0	1

Below are the most recent publications written about "Aging" by people in Profiles.

Guo C, Lan X, Huang C, Wang X, Zhang D, Zeng L, Wang Q, Xiang Y, Li J. Muscle-specific transcriptomic and metabolomic signatures reveal heterogeneous aging trajectories and altered intercellular communication in male murine skeletal muscle. Biogerontology. 2026 Feb 05; 27(2):48.

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Obeso A, Drouard G, Jelenkovic A, Ordo?ana JR, S?nchez-Romera JF, Colodro-Conde L, Ollikainen M, Aaltonen S, Corley RP, Huibregtse BM, Medda E, Fagnani C, Toccaceli V, Gatz M, Butler DA, Bartels M, Ligthart L, de Geus EJ, Christensen K, Skytthe A, Kyvik KO, Medland SE, Gordon SD, Rasmussen FE, Tynelius P, Franz CE, Kremen WS, Lyons MJ, Spector T, Mangino M, Lachance G, Magnusson PK, Pedersen NL, Dahl Aslan AK, Duncan GE, Buchwald D, Pyun H, Lee J, Lee SJ, Sung J, Bruins S, Pool R, Eriksson A, Martin NG, Boomsma DI, Kaprio J, Silventoinen K. Genetic and environmental effects on weight gain from young adulthood to old age and its association with body mass index in early young adulthood: an individual-based pooled analysis of 16 twin cohorts. Int J Obes (Lond). 2026 Apr; 50(4):768-776.

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Thomas JM, Smith ZH, Kent JA, Boyer KA. A distal-to-proximal shift is not a requisite mechanism for greater metabolic cost of walking in older adults. J Biomech. 2026 Jan; 195:113109.

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Zhang B, McEvoy LK, Nguyen S, Espeland MA, Rapp SR, Horvath S, Lu AT, LaCroix AZ, Nievergelt CM, Maihofer AX, Resnick SM, Mielke MM, Beckman K, Li D, Silver B, Manson JE, Ferrucci L, Shadyab AH. Epigenetic clocks and longitudinal plasma biomarkers of Alzheimer's disease. Alzheimers Dement. 2025 Dec; 21(12):e70983.

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Gordon S, Lee JS, Scott TM, Bhupathiraju S, Ordovas J, Kelly RS, Bhadelia R, Koo BB, Bigornia S, Tucker KL, Palacios N. Metabolites and MRI-derived markers of dementia risk in a Puerto Rican cohort. Metabolomics. 2025 Nov 13; 21(6):161.

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Chen F, Guan Y, Koo BB, Scott TM, Li W, Mangano KM, Garelnabi M, Bhadelia R, Tucker KL. Associations of serum magnesium and magnesium intake with brain morphology and cognitive function in Puerto Rican adults. J Gerontol A Biol Sci Med Sci. 2025 11 06; 80(12).

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Sheehan PW, Fass SB, Sapkota D, Kang S, Hollis HC, Lawrence JH, Park S, Sharma A, Schafer DP, Anafi RC, Dougherty JD, Fryer JD, Musiek ES. A glial circadian gene expression atlas reveals cell-type and disease-specific reprogramming in response to amyloid pathology or aging. Nat Neurosci. 2025 Nov; 28(11):2366-2379.

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Krunic A, Bellio TA, Cohen BZ, Labadorf A, Stein TD, Lin H, Mellott TJ, Blusztajn JK. Brain DNA Methylation Atlas of AppNL-G-F Alzheimer's Disease Model Mice Across Age and Region Reveals Choline-Induced Resilience. Aging Cell. 2025 Nov; 24(11):e70241.

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Jeffries AM, Yu T, Ziegenfuss JS, Tolles AK, Baer CE, Sotelo CB, Kim Y, Weng Z, Lodato MA. Single-cell transcriptomic and genomic changes in the ageing human brain. Nature. 2025 10; 646(8085):657-666.

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Sullivan EV, Sassoon SA, Pohl KM, Saranathan M, Zahr NM, Pfefferbaum A. Physiological and brain mechanisms contributing to postural tremor in aging with and without alcohol use disorder. Transl Psychiatry. 2025 Sep 01; 15(1):338.

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