Leonard Shultz to T-Lymphocytes
This is a "connection" page, showing publications Leonard Shultz has written about T-Lymphocytes.
Connection Strength
2.791
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Brehm MA, Kenney LL, Wiles MV, Low BE, Tisch RM, Burzenski L, Mueller C, Greiner DL, Shultz LD. Lack of acute xenogeneic graft- versus-host disease, but retention of T-cell function following engraftment of human peripheral blood mononuclear cells in NSG mice deficient in MHC class I and II expression. FASEB J. 2019 03; 33(3):3137-3151.
Score: 0.443
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Darguzyte M, Antczak P, Bachurski D, Hoelker P, Abedpour N, Gholamipoorfard R, Schl??er HA, Wennhold K, Thelen M, Garcia-Marquez MA, Koenig J, Schneider A, Braun T, Klawonn F, Damrat M, Rahman M, Kleid JM, Theobald SJ, Bauer E, von Kaisenberg C, Talbot SR, Shultz LD, Soper B, Stripecke R. Long-Term Human Immune Reconstitution, T-Cell Development, and Immune Reactivity in Mice Lacking the Murine Major Histocompatibility Complex: Validation with Cellular and Gene Expression Profiles. Cells. 2024 10 12; 13(20).
Score: 0.167
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Yang J, Jiao J, Draheim KM, Yang G, Yang H, Yao LC, Shultz LD, Greiner DL, Rajagopal D, Vessillier S, Maier CC, Mohanan S, Cai D, Cheng M, Brehm MA, Keck JG. Simultaneous evaluation of treatment efficacy and toxicity for bispecific T-cell engager therapeutics in a humanized mouse model. FASEB J. 2023 06; 37(6):e22995.
Score: 0.152
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Christianson SW, Greiner DL, Deluca D, Leif J, Phillips NE, Hayes SM, Hayashi S, Joliat MJ, Lyons BL, Shultz LD. T cell developmental defects in 'viable motheaten' mice deficient in SHP-1 protein-tyrosine phosphatase. Developmental defects are corrected in vitro in the presence of normal hematopoietic-origin stromal cells and in vivo by exogenous IL-7. J Autoimmun. 2002 Mar; 18(2):119-30.
Score: 0.139
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Bhatta M, Shenoy GN, Loyall JL, Gray BD, Bapardekar M, Conway A, Minderman H, Kelleher RJ, Carreno BM, Linette G, Shultz LD, Odunsi K, Balu-Iyer SV, Pak KY, Bankert RB. Novel phosphatidylserine-binding molecule enhances antitumor T-cell responses by targeting immunosuppressive exosomes in human tumor microenvironments. J Immunother Cancer. 2021 10; 9(10).
Score: 0.136
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Shultz LD, Lang PA, Christianson SW, Gott B, Lyons B, Umeda S, Leiter E, Hesselton R, Wagar EJ, Leif JH, Kollet O, Lapidot T, Greiner DL. NOD/LtSz-Rag1null mice: an immunodeficient and radioresistant model for engraftment of human hematolymphoid cells, HIV infection, and adoptive transfer of NOD mouse diabetogenic T cells. J Immunol. 2000 Mar 01; 164(5):2496-507.
Score: 0.121
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Ono R, Watanabe T, Kawakami E, Iwasaki M, Tomizawa-Murasawa M, Matsuda M, Najima Y, Takagi S, Fujiki S, Sato R, Mochizuki Y, Yoshida H, Sato K, Yabe H, Kato S, Saito Y, Taniguchi S, Shultz LD, Ohara O, Amagai M, Koseki H, Ishikawa F. Co-activation of macrophages and T cells contribute to chronic GVHD in human IL-6 transgenic humanised mouse model. EBioMedicine. 2019 Mar; 41:584-596.
Score: 0.113
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Serreze DV, Chapman HD, Varnum DS, Gerling I, Leiter EH, Shultz LD. Initiation of autoimmune diabetes in NOD/Lt mice is MHC class I-dependent. J Immunol. 1997 Apr 15; 158(8):3978-86.
Score: 0.099
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Serreze DV, Chapman HD, Varnum DS, Hanson MS, Reifsnyder PC, Richard SD, Fleming SA, Leiter EH, Shultz LD. B lymphocytes are essential for the initiation of T cell-mediated autoimmune diabetes: analysis of a new "speed congenic" stock of NOD.Ig mu null mice. J Exp Med. 1996 Nov 01; 184(5):2049-53.
Score: 0.096
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Cheng F, Twardowski L, Reifenberg K, Winter K, Canisius A, Pross E, Fan J, Schmitt E, Shultz LD, Lackner KJ, Torzewski M. Combined B, T and NK Cell Deficiency Accelerates Atherosclerosis in BALB/c Mice. PLoS One. 2016; 11(8):e0157311.
Score: 0.095
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Christianson SW, Greiner DL, Schweitzer IB, Gott B, Beamer GL, Schweitzer PA, Hesselton RM, Shultz LD. Role of natural killer cells on engraftment of human lymphoid cells and on metastasis of human T-lymphoblastoid leukemia cells in C57BL/6J-scid mice and in C57BL/6J-scid bg mice. Cell Immunol. 1996 Aug 01; 171(2):186-99.
Score: 0.095
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Ali R, Babad J, Follenzi A, Gebe JA, Brehm MA, Nepom GT, Shultz LD, Greiner DL, DiLorenzo TP. Genetically modified human CD4(+) T cells can be evaluated in?vivo without lethal graft-versus-host disease. Immunology. 2016 08; 148(4):339-51.
Score: 0.095
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Yokota SJ, Facciponte JG, Kelleher RJ, Shultz LD, Loyall JL, Parsons RR, Odunsi K, Frelinger JG, Lord EM, Gerber SA, Balu-Iyer SV, Bankert RB. Changes in ovarian tumor cell number, tumor vasculature, and T cell function monitored in vivo using a novel xenograft model. Cancer Immun. 2013; 13:11.
Score: 0.076
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Wilson DW, Oslund KL, Lyons B, Foreman O, Burzenski L, Svenson KL, Chase TH, Shultz LD. Inflammatory dilated cardiomyopathy in Abcg5-deficient mice. Toxicol Pathol. 2013 Aug; 41(6):880-92.
Score: 0.073
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Jaiswal S, Pazoles P, Woda M, Shultz LD, Greiner DL, Brehm MA, Mathew A. Enhanced humoral and HLA-A2-restricted dengue virus-specific T-cell responses in humanized BLT NSG mice. Immunology. 2012 Jul; 136(3):334-43.
Score: 0.071
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Shultz LD, Brehm MA, Bavari S, Greiner DL. Humanized mice as a preclinical tool for infectious disease and biomedical research. Ann N Y Acad Sci. 2011 Dec; 1245:50-4.
Score: 0.069
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Kumar P, Ban HS, Kim SS, Wu H, Pearson T, Greiner DL, Laouar A, Yao J, Haridas V, Habiro K, Yang YG, Jeong JH, Lee KY, Kim YH, Kim SW, Peipp M, Fey GH, Manjunath N, Shultz LD, Lee SK, Shankar P. T cell-specific siRNA delivery suppresses HIV-1 infection in humanized mice. Cell. 2008 Aug 22; 134(4):577-86.
Score: 0.054
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Simpson-Abelson MR, Sonnenberg GF, Takita H, Yokota SJ, Conway TF, Kelleher RJ, Shultz LD, Barcos M, Bankert RB. Long-term engraftment and expansion of tumor-derived memory T cells following the implantation of non-disrupted pieces of human lung tumor into NOD-scid IL2Rgamma(null) mice. J Immunol. 2008 May 15; 180(10):7009-18.
Score: 0.054
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Zhou J, Chen J, Zhong R, Mokotoff M, Shultz LD, Ball ED. Targeting gastrin-releasing peptide receptors on small cell lung cancer cells with a bispecific molecule that activates polyclonal T lymphocytes. Clin Cancer Res. 2006 Apr 01; 12(7 Pt 1):2224-31.
Score: 0.046
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Spencer L, Shultz L, Rajan TV. T cells are required for host protection against Brugia malayi but need not produce or respond to interleukin-4. Infect Immun. 2003 Jun; 71(6):3097-106.
Score: 0.038
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Leiter EH, Beamer WG, Shultz LD. The effect of immunosuppression on streptozotocin-induced diabetes in C57BL/KsJ mice. Diabetes. 1983 Feb; 32(2):148-55.
Score: 0.037
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Hashimoto Y, Dorshkind K, Montecino-Rodriguez E, Taguchi N, Shultz L, Gershwin ME. NZB mice exhibit a primary T cell defect in fetal thymic organ culture. J Immunol. 2000 Feb 01; 164(3):1569-75.
Score: 0.030
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Babu S, Shultz LD, Rajan TV. T cells facilitate Brugia malayi development in TCRalpha(null) mice. Exp Parasitol. 1999 Sep; 93(1):55-7.
Score: 0.029
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Babu S, Shultz LD, Klei TR, Rajan TV. Immunity in experimental murine filariasis: roles of T and B cells revisited. Infect Immun. 1999 Jun; 67(6):3166-7.
Score: 0.029
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Foy TM, McIlraith M, Masters SR, Dunn JJ, Rossini AA, Shultz LD, Hesselton RA, Wagar EJ, Lipsky PE, Noelle RJ, Greiner DL. Blockade of CD40-CD154 interferes with human T cell engraftment in scid mice. Cell Transplant. 1998 Jan-Feb; 7(1):25-35.
Score: 0.026
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Takeoka Y, Chen SY, Boyd RL, Tsuneyama K, Taguchi N, Morita S, Yago H, Suehiro S, Ansari AA, Shultz LD, Gershwin ME. A comparative analysis of the murine thymic microenvironment in normal, autoimmune, and immunodeficiency states. Dev Immunol. 1997; 5(2):79-89.
Score: 0.024
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Greiner DL, Shultz LD, Deluca D, Leif JH, Christianson SW, Hesselton RM. HIV-1 infectivity of human T cells in a human/murine chimeric fetal thymic organ culture system. In Vivo. 1996 Jan-Feb; 10(1):33-7.
Score: 0.023
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DeLuca D, Bluestone JA, Shultz LD, Sharrow SO, Tatsumi Y. Programmed differentiation of murine thymocytes during fetal thymus organ culture. J Immunol Methods. 1995 Jan 13; 178(1):13-29.
Score: 0.021
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Shultz LD, Schweitzer PA, Christianson SW, Gott B, Schweitzer IB, Tennent B, McKenna S, Mobraaten L, Rajan TV, Greiner DL, et al. Multiple defects in innate and adaptive immunologic function in NOD/LtSz-scid mice. J Immunol. 1995 Jan 01; 154(1):180-91.
Score: 0.021
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Gerling IC, Friedman H, Greiner DL, Shultz LD, Leiter EH. Multiple low-dose streptozocin-induced diabetes in NOD-scid/scid mice in the absence of functional lymphocytes. Diabetes. 1994 Mar; 43(3):433-40.
Score: 0.020
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Hayes SM, Shultz LD, Greiner DL. Localization of prothymocytes from wild-type and viable motheaten mice following intravenous injection into irradiated adoptive recipients. Cell Immunol. 1994 Feb; 153(2):344-55.
Score: 0.020
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Potter CS, Wang Z, Silva KA, Kennedy VE, Stearns TM, Burzenski L, Shultz LD, Hogenesch H, Sundberg JP. Chronic proliferative dermatitis in Sharpin null mice: development of an autoinflammatory disease in the absence of B and T lymphocytes and IL4/IL13 signaling. PLoS One. 2014; 9(1):e85666.
Score: 0.020
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Aryee KE, Shultz LD, Brehm MA. Immunodeficient mouse model for human hematopoietic stem cell engraftment and immune system development. Methods Mol Biol. 2014; 1185:267-78.
Score: 0.020
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Koo GC, Rosen H, Sirotina A, Ma XD, Shultz LD. Anti-CD11b antibody prevents immunopathologic changes in viable moth-eaten bone marrow chimeric mice. J Immunol. 1993 Dec 15; 151(12):6733-41.
Score: 0.020
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Matsuoka N, Martin A, Concepcion ES, Unger P, Shultz LD, Davies TF. Preservation of functioning human thyroid organoids in the scid mouse: II. Biased use of intrathyroidal T cell receptor V genes. J Clin Endocrinol Metab. 1993 Aug; 77(2):311-5.
Score: 0.019
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Sundberg JP, Boggess D, Sundberg BA, Beamer WG, Shultz LD. Epidermal dendritic cell populations in the flaky skin mutant mouse. Immunol Invest. 1993 Jul; 22(5):389-401.
Score: 0.019
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Kapasi ZF, Burton GF, Shultz LD, Tew JG, Szakal AK. Induction of functional follicular dendritic cell development in severe combined immunodeficiency mice. Influence of B and T cells. J Immunol. 1993 Apr 01; 150(7):2648-58.
Score: 0.019
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Kapasi ZF, Burton GF, Shultz LD, Tew JG, Szakal AK. Cellular requirements for functional reconstitution of follicular dendritic cells in SCID mice. Adv Exp Med Biol. 1993; 329:383-6.
Score: 0.018
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Serreze DV, Leiter EH, Shultz LD. Transplantation analysis of B cell destruction in (NOD x CBA)F1 mouse bone marrow chimeras. Diabetologia. 1990 Feb; 33(2):84-92.
Score: 0.015
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Giassi LJ, Pearson T, Shultz LD, Laning J, Biber K, Kraus M, Woda BA, Schmidt MR, Woodland RT, Rossini AA, Greiner DL. Expanded CD34+ human umbilical cord blood cells generate multiple lymphohematopoietic lineages in NOD-scid IL2rgamma(null) mice. Exp Biol Med (Maywood). 2008 Aug; 233(8):997-1012.
Score: 0.014
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Komschlies KL, Greiner DL, Shultz L, Goldschneider I. Defective lymphopoiesis in the bone marrow of motheaten (me/me) and viable motheaten (mev/mev) mutant mice. III. Normal mouse bone marrow cells enable mev/mev prothymocytes to generate thymocytes after intravenous transfer. J Exp Med. 1987 Oct 01; 166(4):1162-7.
Score: 0.013
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Ramesh M, Paciorkowski N, Dash Y, Shultz L, Rajan TV. Acute but not chronic macrophage recruitment in filarial infections in mice is dependent on C-C chemokine ligand 2. Parasite Immunol. 2007 Aug; 29(8):395-404.
Score: 0.013
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Leiter EH, Prochazka M, Shultz LD. Effect of immunodeficiency on diabetogenesis in genetically diabetic (db/db) mice. J Immunol. 1987 May 15; 138(10):3224-9.
Score: 0.013
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Kuzin II, Ugine GD, Barth RK, Shultz LD, Nahm MH, Young FM, Bottaro A. A new murine model of humoral immuno-deficiency specifically affects class switching to T-independent antigens. Eur J Immunol. 2004 Jul; 34(7):1807-16.
Score: 0.010
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Johnson DA, Shultz LD, Bedigian HG. Immunodeficiency and reticulum cell sarcoma in mice segregating for HRS/J and SJL/J genes. Leuk Res. 1982; 6(5):711-20.
Score: 0.009
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Wagar EJ, Cromwell MA, Shultz LD, Woda BA, Sullivan JL, Hesselton RM, Greiner DL. Regulation of human cell engraftment and development of EBV-related lymphoproliferative disorders in Hu-PBL-scid mice. J Immunol. 2000 Jul 01; 165(1):518-27.
Score: 0.008
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Paciorkowski N, Porte P, Shultz LD, Rajan TV. B1 B lymphocytes play a critical role in host protection against lymphatic filarial parasites. J Exp Med. 2000 Feb 21; 191(4):731-6.
Score: 0.008
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Sidman CL, Shultz LD, Unanue ER. The mouse mutant "motheaten". I. Development of lymphocyte populations. J Immunol. 1978 Dec; 121(6):2392-8.
Score: 0.007
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Sidman CL, Shultz LD, Unanue ER. The mouse mutant "motheaten." II. Functional studies of the immune system. J Immunol. 1978 Dec; 121(6):2399-404.
Score: 0.007
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Martin A, Matsuoka N, Zhang J, Zhou A, Nakashima M, Unger P, Schwartz AE, Friedman EW, Shultz LD, Davies TF. Preservation of functioning human thyroid "organoids" in the scid mouse. IV. In vivo selection of an intrathyroidal T cell receptor repertoire. Endocrinology. 1997 Nov; 138(11):4868-75.
Score: 0.006
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Takeoka Y, Chen SY, Yago H, Boyd R, Suehiro S, Shultz LD, Ansari AA, Gershwin ME. The murine thymic microenvironment: changes with age. Int Arch Allergy Immunol. 1996 Sep; 111(1):5-12.
Score: 0.006
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Serreze DV, Leiter EH, Hanson MS, Christianson SW, Shultz LD, Hesselton RM, Greiner DL. Emv30null NOD-scid mice. An improved host for adoptive transfer of autoimmune diabetes and growth of human lymphohematopoietic cells. Diabetes. 1995 Dec; 44(12):1392-8.
Score: 0.006
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McCune JM, Namikawa R, Kaneshima H, Shultz LD, Lieberman M, Weissman IL. The SCID-hu mouse: murine model for the analysis of human hematolymphoid differentiation and function. Science. 1988 Sep 23; 241(4873):1632-9.
Score: 0.003
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Hagiya M, Davis DD, Shultz LD, Sakano H. Non-germ-line elements (NGE) are present in the T cell receptor beta-chain genes isolated from the mutant mouse, motheaten (me/me). J Immunol. 1986 Apr 01; 136(7):2697-700.
Score: 0.003
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Clark EA, Shultz LD, Pollack SB. Mutations in mice that influence natural killer (NK) cell activity. Immunogenetics. 1981 Mar 01; 12(5-6):601-13.
Score: 0.002