Header Logo

Connection

Roger Davis to JNK Mitogen-Activated Protein Kinases

This is a "connection" page, showing publications Roger Davis has written about JNK Mitogen-Activated Protein Kinases.
  1. Girnius N, Edwards YJ, Garlick DS, Davis RJ. The cJUN NH2-terminal kinase (JNK) signaling pathway promotes genome stability and prevents tumor initiation. Elife. 2018 06 01; 7.
    View in: PubMed
    Score: 0.572
  2. Girnius N, Edwards YJK, Davis RJ. The cJUN NH2-terminal kinase (JNK) pathway contributes to mouse mammary gland remodeling during involution. Cell Death Differ. 2018 09; 25(9):1702-1715.
    View in: PubMed
    Score: 0.562
  3. Girnius N, Davis RJ. JNK Promotes Epithelial Cell Anoikis by Transcriptional and Post-translational Regulation of BH3-Only Proteins. Cell Rep. 2017 Nov 14; 21(7):1910-1921.
    View in: PubMed
    Score: 0.551
  4. Kant S, Standen CL, Morel C, Jung DY, Kim JK, Swat W, Flavell RA, Davis RJ. A Protein Scaffold Coordinates SRC-Mediated JNK Activation in Response to Metabolic Stress. Cell Rep. 2017 Sep 19; 20(12):2775-2783.
    View in: PubMed
    Score: 0.545
  5. Vernia S, Cavanagh-Kyros J, Barrett T, Tournier C, Davis RJ. Fibroblast Growth Factor 21 Mediates Glycemic Regulation by Hepatic JNK. Cell Rep. 2016 Mar 15; 14(10):2273-80.
    View in: PubMed
    Score: 0.489
  6. H?bner A, Mulholland DJ, Standen CL, Karasarides M, Cavanagh-Kyros J, Barrett T, Chi H, Greiner DL, Tournier C, Sawyers CL, Flavell RA, Wu H, Davis RJ. JNK and PTEN cooperatively control the development of invasive adenocarcinoma of the prostate. Proc Natl Acad Sci U S A. 2012 Jul 24; 109(30):12046-51.
    View in: PubMed
    Score: 0.379
  7. Xu P, Das M, Reilly J, Davis RJ. JNK regulates FoxO-dependent autophagy in neurons. Genes Dev. 2011 Feb 15; 25(4):310-22.
    View in: PubMed
    Score: 0.345
  8. Cellurale C, Sabio G, Kennedy NJ, Das M, Barlow M, Sandy P, Jacks T, Davis RJ. Requirement of c-Jun NH(2)-terminal kinase for Ras-initiated tumor formation. Mol Cell Biol. 2011 Apr; 31(7):1565-76.
    View in: PubMed
    Score: 0.344
  9. Morel C, Standen CL, Jung DY, Gray S, Ong H, Flavell RA, Kim JK, Davis RJ. Requirement of JIP1-mediated c-Jun N-terminal kinase activation for obesity-induced insulin resistance. Mol Cell Biol. 2010 Oct; 30(19):4616-25.
    View in: PubMed
    Score: 0.332
  10. Xu P, Davis RJ. c-Jun NH2-terminal kinase is required for lineage-specific differentiation but not stem cell self-renewal. Mol Cell Biol. 2010 Mar; 30(6):1329-40.
    View in: PubMed
    Score: 0.320
  11. Standen CL, Kennedy NJ, Flavell RA, Davis RJ. Signal transduction cross talk mediated by Jun N-terminal kinase-interacting protein and insulin receptor substrate scaffold protein complexes. Mol Cell Biol. 2009 Sep; 29(17):4831-40.
    View in: PubMed
    Score: 0.308
  12. Weston CR, Davis RJ. The JNK signal transduction pathway. Curr Opin Cell Biol. 2007 Apr; 19(2):142-9.
    View in: PubMed
    Score: 0.261
  13. Sluss HK, Davis RJ. H2AX is a target of the JNK signaling pathway that is required for apoptotic DNA fragmentation. Mol Cell. 2006 Jul 21; 23(2):152-3.
    View in: PubMed
    Score: 0.251
  14. Ventura JJ, H?bner A, Zhang C, Flavell RA, Shokat KM, Davis RJ. Chemical genetic analysis of the time course of signal transduction by JNK. Mol Cell. 2006 Mar 03; 21(5):701-10.
    View in: PubMed
    Score: 0.245
  15. Brancho D, Ventura JJ, Jaeschke A, Doran B, Flavell RA, Davis RJ. Role of MLK3 in the regulation of mitogen-activated protein kinase signaling cascades. Mol Cell Biol. 2005 May; 25(9):3670-81.
    View in: PubMed
    Score: 0.231
  16. Ventura JJ, Cogswell P, Flavell RA, Baldwin AS, Davis RJ. JNK potentiates TNF-stimulated necrosis by increasing the production of cytotoxic reactive oxygen species. Genes Dev. 2004 Dec 01; 18(23):2905-15.
    View in: PubMed
    Score: 0.224
  17. Weston CR, Wong A, Hall JP, Goad ME, Flavell RA, Davis RJ. The c-Jun NH2-terminal kinase is essential for epidermal growth factor expression during epidermal morphogenesis. Proc Natl Acad Sci U S A. 2004 Sep 28; 101(39):14114-9.
    View in: PubMed
    Score: 0.221
  18. Jaeschke A, Czech MP, Davis RJ. An essential role of the JIP1 scaffold protein for JNK activation in adipose tissue. Genes Dev. 2004 Aug 15; 18(16):1976-80.
    View in: PubMed
    Score: 0.220
  19. Kant S, Barrett T, Vertii A, Noh YH, Jung DY, Kim JK, Davis RJ. Role of the mixed-lineage protein kinase pathway in the metabolic stress response to obesity. Cell Rep. 2013 Aug 29; 4(4):681-8.
    View in: PubMed
    Score: 0.103
  20. Mazzitelli S, Xu P, Ferrer I, Davis RJ, Tournier C. The loss of c-Jun N-terminal protein kinase activity prevents the amyloidogenic cleavage of amyloid precursor protein and the formation of amyloid plaques in vivo. J Neurosci. 2011 Nov 23; 31(47):16969-76.
    View in: PubMed
    Score: 0.091
  21. Podkowa M, Zhao X, Chow CW, Coffey ET, Davis RJ, Attisano L. Microtubule stabilization by bone morphogenetic protein receptor-mediated scaffolding of c-Jun N-terminal kinase promotes dendrite formation. Mol Cell Biol. 2010 May; 30(9):2241-50.
    View in: PubMed
    Score: 0.081
  22. H?bner A, Cavanagh-Kyros J, Rincon M, Flavell RA, Davis RJ. Functional cooperation of the proapoptotic Bcl2 family proteins Bmf and Bim in vivo. Mol Cell Biol. 2010 Jan; 30(1):98-105.
    View in: PubMed
    Score: 0.080
  23. Morel C, Carlson SM, White FM, Davis RJ. Mcl-1 integrates the opposing actions of signaling pathways that mediate survival and apoptosis. Mol Cell Biol. 2009 Jul; 29(14):3845-52.
    View in: PubMed
    Score: 0.076
  24. Ongusaha PP, Qi HH, Raj L, Kim YB, Aaronson SA, Davis RJ, Shi Y, Liao JK, Lee SW. Identification of ROCK1 as an upstream activator of the JIP-3 to JNK signaling axis in response to UVB damage. Sci Signal. 2008 Nov 25; 1(47):ra14.
    View in: PubMed
    Score: 0.074
  25. Alcorn JF, Guala AS, van der Velden J, McElhinney B, Irvin CG, Davis RJ, Janssen-Heininger YM. Jun N-terminal kinase 1 regulates epithelial-to-mesenchymal transition induced by TGF-beta1. J Cell Sci. 2008 Apr 01; 121(Pt 7):1036-45.
    View in: PubMed
    Score: 0.070
  26. Jaeschke A, Davis RJ. Metabolic stress signaling mediated by mixed-lineage kinases. Mol Cell. 2007 Aug 03; 27(3):498-508.
    View in: PubMed
    Score: 0.067
  27. Tong C, Yin Z, Song Z, Dockendorff A, Huang C, Mariadason J, Flavell RA, Davis RJ, Augenlicht LH, Yang W. c-Jun NH2-terminal kinase 1 plays a critical role in intestinal homeostasis and tumor suppression. Am J Pathol. 2007 Jul; 171(1):297-303.
    View in: PubMed
    Score: 0.067
  28. Henderson NC, Pollock KJ, Frew J, Mackinnon AC, Flavell RA, Davis RJ, Sethi T, Simpson KJ. Critical role of c-jun (NH2) terminal kinase in paracetamol- induced acute liver failure. Gut. 2007 Jul; 56(7):982-90.
    View in: PubMed
    Score: 0.065
  29. Liao G, Tao Q, Kofron M, Chen JS, Schloemer A, Davis RJ, Hsieh JC, Wylie C, Heasman J, Kuan CY. Jun NH2-terminal kinase (JNK) prevents nuclear beta-catenin accumulation and regulates axis formation in Xenopus embryos. Proc Natl Acad Sci U S A. 2006 Oct 31; 103(44):16313-8.
    View in: PubMed
    Score: 0.064
  30. Kelkar N, Standen CL, Davis RJ. Role of the JIP4 scaffold protein in the regulation of mitogen-activated protein kinase signaling pathways. Mol Cell Biol. 2005 Apr; 25(7):2733-43.
    View in: PubMed
    Score: 0.057
  31. Ventura JJ, Kennedy NJ, Flavell RA, Davis RJ. JNK regulates autocrine expression of TGF-beta1. Mol Cell. 2004 Jul 23; 15(2):269-78.
    View in: PubMed
    Score: 0.055
  32. Kelkar N, Delmotte MH, Weston CR, Barrett T, Sheppard BJ, Flavell RA, Davis RJ. Morphogenesis of the telencephalic commissure requires scaffold protein JNK-interacting protein 3 (JIP3). Proc Natl Acad Sci U S A. 2003 Aug 19; 100(17):9843-8.
    View in: PubMed
    Score: 0.051
  33. Weston CR, Wong A, Hall JP, Goad ME, Flavell RA, Davis RJ. JNK initiates a cytokine cascade that causes Pax2 expression and closure of the optic fissure. Genes Dev. 2003 May 15; 17(10):1271-80.
    View in: PubMed
    Score: 0.050
  34. Kennedy NJ, Davis RJ. Role of JNK in tumor development. Cell Cycle. 2003 May-Jun; 2(3):199-201.
    View in: PubMed
    Score: 0.050
  35. Kennedy NJ, Sluss HK, Jones SN, Bar-Sagi D, Flavell RA, Davis RJ. Suppression of Ras-stimulated transformation by the JNK signal transduction pathway. Genes Dev. 2003 Mar 01; 17(5):629-37.
    View in: PubMed
    Score: 0.050
  36. Hess P, Pihan G, Sawyers CL, Flavell RA, Davis RJ. Survival signaling mediated by c-Jun NH(2)-terminal kinase in transformed B lymphoblasts. Nat Genet. 2002 Sep; 32(1):201-5.
    View in: PubMed
    Score: 0.048
  37. Lei K, Nimnual A, Zong WX, Kennedy NJ, Flavell RA, Thompson CB, Bar-Sagi D, Davis RJ. The Bax subfamily of Bcl2-related proteins is essential for apoptotic signal transduction by c-Jun NH(2)-terminal kinase. Mol Cell Biol. 2002 Jul; 22(13):4929-42.
    View in: PubMed
    Score: 0.047
  38. Weston CR, Davis RJ. The JNK signal transduction pathway. Curr Opin Genet Dev. 2002 Feb; 12(1):14-21.
    View in: PubMed
    Score: 0.046
  39. Hall JP, Davis RJ. Analysis of c-Jun N-terminal kinase regulation and function. Methods Enzymol. 2002; 345:413-25.
    View in: PubMed
    Score: 0.046
  40. Hall JP, Davis RJ. Inhibition of the p38 pathway upregulates macrophage JNK and ERK activities, and the ERK, JNK, and p38 MAP kinase pathways are reprogrammed during differentiation of the murine myeloid M1 cell line. J Cell Biochem. 2002; 86(1):1-11.
    View in: PubMed
    Score: 0.046
  41. Smith AO, Jonassen JA, Preval KM, Davis RJ, Pazour GJ. c-Jun N-terminal kinase (JNK) signaling contributes to cystic burden in polycystic kidney disease. PLoS Genet. 2021 12; 17(12):e1009711.
    View in: PubMed
    Score: 0.046
  42. Boege Y, Malehmir M, Healy ME, Bettermann K, Lorentzen A, Vucur M, Ahuja AK, B?hm F, Mertens JC, Shimizu Y, Frick L, Remouchamps C, Mutreja K, K?hne T, Sundaravinayagam D, Wolf MJ, Rehrauer H, Koppe C, Speicher T, Padrissa-Alt?s S, Maire R, Schattenberg JM, Jeong JS, Liu L, Zwirner S, Boger R, H?ser N, Davis RJ, M?llhaupt B, Moch H, Schulze-Bergkamen H, Clavien PA, Werner S, Borsig L, Luther SA, Jost PJ, Weinlich R, Unger K, Behrens A, Hillert L, Dillon C, Di Virgilio M, Wallach D, Dejardin E, Zender L, Naumann M, Walczak H, Green DR, Lopes M, Lavrik I, Luedde T, Heikenwalder M, Weber A. A Dual Role of Caspase-8 in Triggering and Sensing Proliferation-Associated DNA Damage, a Key Determinant of Liver Cancer Development. Cancer Cell. 2017 09 11; 32(3):342-359.e10.
    View in: PubMed
    Score: 0.034
  43. Liu X, Li H, Rajurkar M, Li Q, Cotton JL, Ou J, Zhu LJ, Goel HL, Mercurio AM, Park JS, Davis RJ, Mao J. Tead and AP1 Coordinate Transcription and Motility. Cell Rep. 2016 Feb 09; 14(5):1169-1180.
    View in: PubMed
    Score: 0.030
  44. Goel HL, Chang C, Pursell B, Leav I, Lyle S, Xi HS, Hsieh CC, Adisetiyo H, Roy-Burman P, Coleman IM, Nelson PS, Vessella RL, Davis RJ, Plymate SR, Mercurio AM. VEGF/neuropilin-2 regulation of Bmi-1 and consequent repression of IGF-IR define a novel mechanism of aggressive prostate cancer. Cancer Discov. 2012 Oct; 2(10):906-21.
    View in: PubMed
    Score: 0.024
  45. Norseen J, Hosooka T, Hammarstedt A, Yore MM, Kant S, Aryal P, Kiernan UA, Phillips DA, Maruyama H, Kraus BJ, Usheva A, Davis RJ, Smith U, Kahn BB. Retinol-binding protein 4 inhibits insulin signaling in adipocytes by inducing proinflammatory cytokines in macrophages through a c-Jun N-terminal kinase- and toll-like receptor 4-dependent and retinol-independent mechanism. Mol Cell Biol. 2012 May; 32(10):2010-9.
    View in: PubMed
    Score: 0.023
  46. Barnat M, Enslen H, Propst F, Davis RJ, Soares S, Nothias F. Distinct roles of c-Jun N-terminal kinase isoforms in neurite initiation and elongation during axonal regeneration. J Neurosci. 2010 Jun 09; 30(23):7804-16.
    View in: PubMed
    Score: 0.021
  47. Morse D, Otterbein LE, Watkins S, Alber S, Zhou Z, Flavell RA, Davis RJ, Choi AM. Deficiency in the c-Jun NH2-terminal kinase signaling pathway confers susceptibility to hyperoxic lung injury in mice. Am J Physiol Lung Cell Mol Physiol. 2003 Jul; 285(1):L250-7.
    View in: PubMed
    Score: 0.012
  48. Reuther-Madrid JY, Kashatus D, Chen S, Li X, Westwick J, Davis RJ, Earp HS, Wang CY, Baldwin AS. The p65/RelA subunit of NF-kappaB suppresses the sustained, antiapoptotic activity of Jun kinase induced by tumor necrosis factor. Mol Cell Biol. 2002 12; 22(23):8175-83.
    View in: PubMed
    Score: 0.012
  49. Lee YH, Giraud J, Davis RJ, White MF. c-Jun N-terminal kinase (JNK) mediates feedback inhibition of the insulin signaling cascade. J Biol Chem. 2003 Jan 31; 278(5):2896-902.
    View in: PubMed
    Score: 0.012
  50. Ghahremani MH, Keramaris E, Shree T, Xia Z, Davis RJ, Flavell R, Slack RS, Park DS. Interaction of the c-Jun/JNK pathway and cyclin-dependent kinases in death of embryonic cortical neurons evoked by DNA damage. J Biol Chem. 2002 Sep 20; 277(38):35586-96.
    View in: PubMed
    Score: 0.012
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.