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Michael Heneka to Microglia

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This is a "connection" page, showing publications Michael Heneka has written about Microglia.
Michael Heneka
Connection Strength
20.005
Microglia
  1. Villacampa N, Sarlus H, Martorell P, Bhalla K, Castro-Gomez S, Vieira-Saecker A, Slutzkin I, H?ndler K, Venegas C, McManus R, Ulas T, Beyer M, Segal E, Heneka MT. Proliferating Microglia Exhibit Unique Transcriptional and Functional Alterations in Alzheimer's Disease. ASN Neuro. 2025; 17(1):2506406.
    View in: PubMed
    Score: 0.774
  2. McManus RM, Komes MP, Griep A, Santarelli F, Schwartz S, Ram?n Perea J, Schlachetzki JCM, Bouvier DS, Khalil MA, Lauterbach MA, Heinemann L, Schl?ter T, Pour MS, Lovotti M, Stahl R, Duthie F, Rodr?guez-Alc?zar JF, Schmidt SV, Spitzer J, Noori P, Maillo A, Boettcher A, Herron B, McConville J, Gomez-Cabrero D, Tegn?r J, Glass CK, Hiller K, Latz E, Heneka MT. NLRP3-mediated glutaminolysis controls microglial phagocytosis to promote Alzheimer's disease progression. Immunity. 2025 Feb 11; 58(2):326-343.e11.
    View in: PubMed
    Score: 0.759
  3. Botella Lucena P, Heneka MT. Inflammatory aspects of Alzheimer's disease. Acta Neuropathol. 2024 Aug 28; 148(1):31.
    View in: PubMed
    Score: 0.736
  4. Scheiblich H, Eikens F, Wischhof L, Opitz S, J?ngling K, Cser?p C, Schmidt SV, Lambertz J, Bellande T, P?sfai B, Geck C, Spitzer J, Odainic A, Castro-Gomez S, Schwartz S, Boussaad I, Kr?ger R, Glaab E, Di Monte DA, Bano D, D?nes ?, Latz E, Melki R, Pape HC, Heneka MT. Microglia rescue neurons from aggregate-induced neuronal dysfunction and death through tunneling nanotubes. Neuron. 2024 Sep 25; 112(18):3106-3125.e8.
    View in: PubMed
    Score: 0.732
  5. Mary A, Mancuso R, Heneka MT. Immune Activation in Alzheimer Disease. Annu Rev Immunol. 2024 Jun; 42(1):585-613.
    View in: PubMed
    Score: 0.726
  6. Dadwal S, Heneka MT. Microglia heterogeneity in health and disease. FEBS Open Bio. 2024 02; 14(2):217-229.
    View in: PubMed
    Score: 0.698
  7. Braatz C, Komes MP, Ravichandran KA, de Fragas MG, Griep A, Schwartz S, McManus RM, Heneka MT. NLRP3-directed antisense oligonucleotides reduce microglial immunoactivities in vitro. J Neurochem. 2024 Oct; 168(10):3467-3481.
    View in: PubMed
    Score: 0.666
  8. Scheiblich H, Dansokho C, Mercan D, Schmidt SV, Bousset L, Wischhof L, Eikens F, Odainic A, Spitzer J, Griep A, Schwartz S, Bano D, Latz E, Melki R, Heneka MT. Microglia jointly degrade fibrillar alpha-synuclein cargo by distribution through tunneling nanotubes. Cell. 2021 09 30; 184(20):5089-5106.e21.
    View in: PubMed
    Score: 0.601
  9. Friker LL, Scheiblich H, Hochheiser IV, Brinkschulte R, Riedel D, Latz E, Geyer M, Heneka MT. ?-Amyloid Clustering around ASC Fibrils Boosts Its Toxicity in Microglia. Cell Rep. 2020 03 17; 30(11):3743-3754.e6.
    View in: PubMed
    Score: 0.541
  10. Luciunaite A, McManus RM, Jankunec M, R?cz I, Dansokho C, Dalgediene I, Schwartz S, Brosseron F, Heneka MT. Soluble A? oligomers and protofibrils induce NLRP3 inflammasome activation in microglia. J Neurochem. 2020 12; 155(6):650-661.
    View in: PubMed
    Score: 0.536
  11. Ising C, Venegas C, Zhang S, Scheiblich H, Schmidt SV, Vieira-Saecker A, Schwartz S, Albasset S, McManus RM, Tejera D, Griep A, Santarelli F, Brosseron F, Opitz S, Stunden J, Merten M, Kayed R, Golenbock DT, Blum D, Latz E, Bu?e L, Heneka MT. NLRP3 inflammasome activation drives tau pathology. Nature. 2019 11; 575(7784):669-673.
    View in: PubMed
    Score: 0.529
  12. Castro-Gomez S, Binder J, Heneka MT. [Neuroinflammation as motor of Alzheimer's disease]. Nervenarzt. 2019 Sep; 90(9):898-906.
    View in: PubMed
    Score: 0.521
  13. Heneka MT. Microglia take centre stage in neurodegenerative disease. Nat Rev Immunol. 2019 02; 19(2):79-80.
    View in: PubMed
    Score: 0.501
  14. Tejera D, Heneka MT. Microglia in Neurodegenerative Disorders. Methods Mol Biol. 2019; 2034:57-67.
    View in: PubMed
    Score: 0.498
  15. Tejera D, Heneka MT. In Vivo Phagocytosis Analysis of Amyloid Beta. Methods Mol Biol. 2019; 2034:287-292.
    View in: PubMed
    Score: 0.498
  16. Villacampa N, Heneka MT. Microglia: You'll Never Walk Alone! Immunity. 2018 02 20; 48(2):195-197.
    View in: PubMed
    Score: 0.469
  17. Dansokho C, Heneka MT. Neuroinflammatory responses in Alzheimer's disease. J Neural Transm (Vienna). 2018 05; 125(5):771-779.
    View in: PubMed
    Score: 0.463
  18. Tejera D, Heneka MT. United Again: STING and the Police. Neuron. 2017 12 20; 96(6):1207-1208.
    View in: PubMed
    Score: 0.463
  19. Venegas C, Kumar S, Franklin BS, Dierkes T, Brinkschulte R, Tejera D, Vieira-Saecker A, Schwartz S, Santarelli F, Kummer MP, Griep A, Gelpi E, Beilharz M, Riedel D, Golenbock DT, Geyer M, Walter J, Latz E, Heneka MT. Microglia-derived ASC specks cross-seed amyloid-? in Alzheimer's disease. Nature. 2017 12 20; 552(7685):355-361.
    View in: PubMed
    Score: 0.463
  20. Scheiblich H, Schl?tter A, Golenbock DT, Latz E, Martinez-Martinez P, Heneka MT. Activation of the NLRP3 inflammasome in microglia: the role of ceramide. J Neurochem. 2017 12; 143(5):534-550.
    View in: PubMed
    Score: 0.458
  21. Sarlus H, Heneka MT. Microglia in Alzheimer's disease. J Clin Invest. 2017 Sep 01; 127(9):3240-3249.
    View in: PubMed
    Score: 0.454
  22. Tejera D, Heneka MT. Microglia in Alzheimer's disease: the good, the bad and the ugly. Curr Alzheimer Res. 2016; 13(4):370-80.
    View in: PubMed
    Score: 0.404
  23. Heneka MT, Carson MJ, El Khoury J, Landreth GE, Brosseron F, Feinstein DL, Jacobs AH, Wyss-Coray T, Vitorica J, Ransohoff RM, Herrup K, Frautschy SA, Finsen B, Brown GC, Verkhratsky A, Yamanaka K, Koistinaho J, Latz E, Halle A, Petzold GC, Town T, Morgan D, Shinohara ML, Perry VH, Holmes C, Bazan NG, Brooks DJ, Hunot S, Joseph B, Deigendesch N, Garaschuk O, Boddeke E, Dinarello CA, Breitner JC, Cole GM, Golenbock DT, Kummer MP. Neuroinflammation in Alzheimer's disease. Lancet Neurol. 2015 Apr; 14(4):388-405.
    View in: PubMed
    Score: 0.384
  24. Heneka MT. Macrophages derived from infiltrating monocytes mediate autoimmune myelin destruction. J Exp Med. 2014 Jul 28; 211(8):1500.
    View in: PubMed
    Score: 0.366
  25. Gaikwad SM, Heneka MT. Studying M1 and M2 states in adult microglia. Methods Mol Biol. 2013; 1041:185-97.
    View in: PubMed
    Score: 0.328
  26. Kummer MP, Vogl T, Axt D, Griep A, Vieira-Saecker A, Jessen F, Gelpi E, Roth J, Heneka MT. Mrp14 deficiency ameliorates amyloid ? burden by increasing microglial phagocytosis and modulation of amyloid precursor protein processing. J Neurosci. 2012 Dec 05; 32(49):17824-9.
    View in: PubMed
    Score: 0.327
  27. Yamanaka M, Ishikawa T, Griep A, Axt D, Kummer MP, Heneka MT. PPAR?/RXRa-induced and CD36-mediated microglial amyloid-? phagocytosis results in cognitive improvement in amyloid precursor protein/presenilin 1 mice. J Neurosci. 2012 Nov 28; 32(48):17321-31.
    View in: PubMed
    Score: 0.326
  28. Terwel D, Steffensen KR, Verghese PB, Kummer MP, Gustafsson J?, Holtzman DM, Heneka MT. Critical role of astroglial apolipoprotein E and liver X receptor-a expression for microglial A? phagocytosis. J Neurosci. 2011 May 11; 31(19):7049-59.
    View in: PubMed
    Score: 0.293
  29. Fleisher-Berkovich S, Filipovich-Rimon T, Ben-Shmuel S, H?lsmann C, Kummer MP, Heneka MT. Distinct modulation of microglial amyloid ? phagocytosis and migration by neuropeptides (i). J Neuroinflammation. 2010 Oct 11; 7:61.
    View in: PubMed
    Score: 0.281
  30. Heneka MT, Nadrigny F, Regen T, Martinez-Hernandez A, Dumitrescu-Ozimek L, Terwel D, Jardanhazi-Kurutz D, Walter J, Kirchhoff F, Hanisch UK, Kummer MP. Locus ceruleus controls Alzheimer's disease pathology by modulating microglial functions through norepinephrine. Proc Natl Acad Sci U S A. 2010 Mar 30; 107(13):6058-63.
    View in: PubMed
    Score: 0.270
  31. Heneka MT, Sastre M, Dumitrescu-Ozimek L, Hanke A, Dewachter I, Kuiperi C, O'Banion K, Klockgether T, Van Leuven F, Landreth GE. Acute treatment with the PPARgamma agonist pioglitazone and ibuprofen reduces glial inflammation and Abeta1-42 levels in APPV717I transgenic mice. Brain. 2005 Jun; 128(Pt 6):1442-53.
    View in: PubMed
    Score: 0.192
  32. Brown GC, Heneka MT. The endotoxin hypothesis of Alzheimer's disease. Mol Neurodegener. 2024 Apr 01; 19(1):30.
    View in: PubMed
    Score: 0.179
  33. Karabag D, Scheiblich H, Griep A, Santarelli F, Schwartz S, Heneka MT, Ising C. Characterizing microglial senescence: Tau as a key player. J Neurochem. 2023 08; 166(3):517-533.
    View in: PubMed
    Score: 0.169
  34. Stratoulias V, Ruiz R, Kanatani S, Osman AM, Keane L, Armengol JA, Rodr?guez-Moreno A, Murgoci AN, Garc?a-Dom?nguez I, Alonso-Bellido I, Gonz?lez Ib??ez F, Picard K, V?zquez-Cabrera G, Posada-P?rez M, Vernoux N, Tejera D, Grabert K, Cheray M, Gonz?lez-Rodr?guez P, P?rez-Villegas EM, Mart?nez-Gallego I, Lastra-Romero A, Brodin D, Avila-Cari?o J, Cao Y, Airavaara M, Uhl?n P, Heneka MT, Tremblay M?, Blomgren K, Venero JL, Joseph B. ARG1-expressing microglia show a distinct molecular signature and modulate postnatal development and function of the mouse brain. Nat Neurosci. 2023 06; 26(6):1008-1020.
    View in: PubMed
    Score: 0.168
  35. Heneka MT. ApoE4 makes microglia trem2bling. Neuron. 2023 01 18; 111(2):142-144.
    View in: PubMed
    Score: 0.165
  36. Paolicelli RC, Sierra A, Stevens B, Tremblay ME, Aguzzi A, Ajami B, Amit I, Audinat E, Bechmann I, Bennett M, Bennett F, Bessis A, Biber K, Bilbo S, Blurton-Jones M, Boddeke E, Brites D, Br?ne B, Brown GC, Butovsky O, Carson MJ, Castellano B, Colonna M, Cowley SA, Cunningham C, Davalos D, De Jager PL, de Strooper B, Denes A, Eggen BJL, Eyo U, Galea E, Garel S, Ginhoux F, Glass CK, Gokce O, Gomez-Nicola D, Gonz?lez B, Gordon S, Graeber MB, Greenhalgh AD, Gressens P, Greter M, Gutmann DH, Haass C, Heneka MT, Heppner FL, Hong S, Hume DA, Jung S, Kettenmann H, Kipnis J, Koyama R, Lemke G, Lynch M, Majewska A, Malcangio M, Malm T, Mancuso R, Masuda T, Matteoli M, McColl BW, Miron VE, Molofsky AV, Monje M, Mracsko E, Nadjar A, Neher JJ, Neniskyte U, Neumann H, Noda M, Peng B, Peri F, Perry VH, Popovich PG, Pridans C, Priller J, Prinz M, Ragozzino D, Ransohoff RM, Salter MW, Schaefer A, Schafer DP, Schwartz M, Simons M, Smith CJ, Streit WJ, Tay TL, Tsai LH, Verkhratsky A, von Bernhardi R, Wake H, Wittamer V, Wolf SA, Wu LJ, Wyss-Coray T. Microglia states and nomenclature: A field at its crossroads. Neuron. 2022 11 02; 110(21):3458-3483.
    View in: PubMed
    Score: 0.162
  37. Ravichandran KA, Heneka MT. Inflammasome activation in neurodegenerative diseases. Essays Biochem. 2021 12 22; 65(7):885-904.
    View in: PubMed
    Score: 0.153
  38. Kummer MP, Ising C, Kummer C, Sarlus H, Griep A, Vieira-Saecker A, Schwartz S, Halle A, Br?ckner M, H?ndler K, Schultze JL, Beyer M, Latz E, Heneka MT. Microglial PD-1 stimulation by astrocytic PD-L1 suppresses neuroinflammation and Alzheimer's disease pathology. EMBO J. 2021 12 15; 40(24):e108662.
    View in: PubMed
    Score: 0.152
  39. Rueda-Carrasco J, Martin-Bermejo MJ, Pereyra G, Mateo MI, Borroto A, Brosseron F, Kummer MP, Schwartz S, L?pez-Atalaya JP, Alarcon B, Esteve P, Heneka MT, Bovolenta P. SFRP1 modulates astrocyte-to-microglia crosstalk in acute and chronic neuroinflammation. EMBO Rep. 2021 11 04; 22(11):e51696.
    View in: PubMed
    Score: 0.150
  40. Scheiblich H, Bousset L, Schwartz S, Griep A, Latz E, Melki R, Heneka MT. Microglial NLRP3 Inflammasome Activation upon TLR2 and TLR5 Ligation by Distinct a-Synuclein Assemblies. J Immunol. 2021 10 15; 207(8):2143-2154.
    View in: PubMed
    Score: 0.150
  41. Joshi P, Riffel F, Satoh K, Enomoto M, Qamar S, Scheiblich H, Villacampa N, Kumar S, Theil S, Parhizkar S, Haass C, Heneka MT, Fraser PE, St George-Hyslop P, Walter J. Differential interaction with TREM2 modulates microglial uptake of modified A? species. Glia. 2021 12; 69(12):2917-2932.
    View in: PubMed
    Score: 0.149
  42. Manabe T, R?cz I, Schwartz S, Oberle L, Santarelli F, Emmrich JV, Neher JJ, Heneka MT. Systemic inflammation induced the delayed reduction of excitatory synapses in the CA3 during ageing. J Neurochem. 2021 11; 159(3):525-542.
    View in: PubMed
    Score: 0.149
  43. Odoj K, Brawek B, Asavapanumas N, Mojtahedi N, Heneka MT, Garaschuk O. In vivo mechanisms of cortical network dysfunction induced by systemic inflammation. Brain Behav Immun. 2021 08; 96:113-126.
    View in: PubMed
    Score: 0.147
  44. Keane L, Antignano I, Riechers SP, Zollinger R, Dumas AA, Offermann N, Bernis ME, Russ J, Graelmann F, McCormick PN, Esser J, Tejera D, Nagano A, Wang J, Chelala C, Biederbick Y, Halle A, Salomoni P, Heneka MT, Capasso M. mTOR-dependent translation amplifies microglia priming in aging mice. J Clin Invest. 2021 01 04; 131(1).
    View in: PubMed
    Score: 0.143
  45. Villacampa N, Heneka MT. Microglia in Alzheimer's disease: Local heroes! J Exp Med. 2020 04 06; 217(4).
    View in: PubMed
    Score: 0.136
  46. Riester K, Brawek B, Savitska D, Fr?hlich N, Zirdum E, Mojtahedi N, Heneka MT, Garaschuk O. In vivo characterization of functional states of cortical microglia during peripheral inflammation. Brain Behav Immun. 2020 07; 87:243-255.
    View in: PubMed
    Score: 0.133
  47. Webers A, Heneka MT, Gleeson PA. The role of innate immune responses and neuroinflammation in amyloid accumulation and progression of Alzheimer's disease. Immunol Cell Biol. 2020 01; 98(1):28-41.
    View in: PubMed
    Score: 0.132
  48. Venegas C, Heneka MT. Inflammasome-mediated innate immunity in Alzheimer's disease. FASEB J. 2019 12; 33(12):13075-13084.
    View in: PubMed
    Score: 0.132
  49. Mercan D, Heneka MT. Norepinephrine as a modulator of microglial dynamics. Nat Neurosci. 2019 11; 22(11):1745-1746.
    View in: PubMed
    Score: 0.132
  50. Tejera D, Mercan D, Sanchez-Caro JM, Hanan M, Greenberg D, Soreq H, Latz E, Golenbock D, Heneka MT. Systemic inflammation impairs microglial A? clearance through NLRP3 inflammasome. EMBO J. 2019 09 02; 38(17):e101064.
    View in: PubMed
    Score: 0.129
  51. Kalinin S, Gonz?lez-Prieto M, Scheiblich H, Lisi L, Kusumo H, Heneka MT, Madrigal JLM, Pandey SC, Feinstein DL. Transcriptome analysis of alcohol-treated microglia reveals downregulation of beta amyloid phagocytosis. J Neuroinflammation. 2018 May 14; 15(1):141.
    View in: PubMed
    Score: 0.119
  52. Unger MS, Marschallinger J, Kaindl J, Klein B, Johnson M, Khundakar AA, Ro?ner S, Heneka MT, Couillard-Despres S, Rockenstein E, Masliah E, Attems J, Aigner L. Doublecortin expression in CD8+ T-cells and microglia at sites of amyloid-? plaques: A potential role in shaping plaque pathology? Alzheimers Dement. 2018 08; 14(8):1022-1037.
    View in: PubMed
    Score: 0.118
  53. Labzin LI, Heneka MT, Latz E. Innate Immunity and Neurodegeneration. Annu Rev Med. 2018 01 29; 69:437-449.
    View in: PubMed
    Score: 0.115
  54. Kemmerling N, Wunderlich P, Theil S, Linnartz-Gerlach B, Hersch N, Hoffmann B, Heneka MT, de Strooper B, Neumann H, Walter J. Intramembranous processing by ?-secretase regulates reverse signaling of ephrin-B2 in migration of microglia. Glia. 2017 07; 65(7):1103-1118.
    View in: PubMed
    Score: 0.110
  55. Heneka MT. Inflammasome activation and innate immunity in Alzheimer's disease. Brain Pathol. 2017 03; 27(2):220-222.
    View in: PubMed
    Score: 0.110
  56. Zimmermann J, Emrich M, Krauthausen M, Saxe S, Nitsch L, Heneka MT, Campbell IL, M?ller M. IL-17A Promotes Granulocyte Infiltration, Myelin Loss, Microglia Activation, and Behavioral Deficits During Cuprizone-Induced Demyelination. Mol Neurobiol. 2018 02; 55(2):946-957.
    View in: PubMed
    Score: 0.109
  57. Su?rez-Calvet M, Kleinberger G, Araque Caballero M?, Brendel M, Rominger A, Alcolea D, Fortea J, Lle? A, Blesa R, Gispert JD, S?nchez-Valle R, Antonell A, Rami L, Molinuevo JL, Brosseron F, Trasch?tz A, Heneka MT, Struyfs H, Engelborghs S, Sleegers K, Van Broeckhoven C, Zetterberg H, Nellg?rd B, Blennow K, Crispin A, Ewers M, Haass C. sTREM2 cerebrospinal fluid levels are a potential biomarker for microglia activity in early-stage Alzheimer's disease and associate with neuronal injury markers. EMBO Mol Med. 2016 05; 8(5):466-76.
    View in: PubMed
    Score: 0.103
  58. Heneka MT, Kummer MP, Latz E. Innate immune activation in neurodegenerative disease. Nat Rev Immunol. 2014 Jul; 14(7):463-77.
    View in: PubMed
    Score: 0.091
  59. Rapic S, Backes H, Viel T, Kummer MP, Monfared P, Neumaier B, Vollmar S, Hoehn M, Van der Linden A, Heneka MT, Jacobs AH. Imaging microglial activation and glucose consumption in a mouse model of Alzheimer's disease. Neurobiol Aging. 2013 Jan; 34(1):351-4.
    View in: PubMed
    Score: 0.079
  60. Liu S, Liu Y, Hao W, Wolf L, Kiliaan AJ, Penke B, R?be CE, Walter J, Heneka MT, Hartmann T, Menger MD, Fassbender K. TLR2 is a primary receptor for Alzheimer's amyloid ? peptide to trigger neuroinflammatory activation. J Immunol. 2012 Feb 01; 188(3):1098-107.
    View in: PubMed
    Score: 0.076
  61. Mildner A, Schlevogt B, Kierdorf K, B?ttcher C, Erny D, Kummer MP, Quinn M, Br?ck W, Bechmann I, Heneka MT, Priller J, Prinz M. Distinct and non-redundant roles of microglia and myeloid subsets in mouse models of Alzheimer's disease. J Neurosci. 2011 Aug 03; 31(31):11159-71.
    View in: PubMed
    Score: 0.074
  62. Juckel G, Manitz MP, Br?ne M, Friebe A, Heneka MT, Wolf RJ. Microglial activation in a neuroinflammational animal model of schizophrenia--a pilot study. Schizophr Res. 2011 Sep; 131(1-3):96-100.
    View in: PubMed
    Score: 0.074
  63. Tamboli IY, Barth E, Christian L, Siepmann M, Kumar S, Singh S, Tolksdorf K, Heneka MT, L?tjohann D, Wunderlich P, Walter J. Statins promote the degradation of extracellular amyloid {beta}-peptide by microglia via stimulation of exosome-associated insulin-degrading enzyme (IDE) secretion. J Biol Chem. 2010 Nov 26; 285(48):37405-14.
    View in: PubMed
    Score: 0.070
  64. Schlachetzki JC, Fiebich BL, Haake E, de Oliveira AC, Candelario-Jalil E, Heneka MT, H?ll M. Norepinephrine enhances the LPS-induced expression of COX-2 and secretion of PGE2 in primary rat microglia. J Neuroinflammation. 2010 Jan 11; 7:2.
    View in: PubMed
    Score: 0.067
  65. Weberpals M, Hermes M, Hermann S, Kummer MP, Terwel D, Semmler A, Berger M, Sch?fers M, Heneka MT. NOS2 gene deficiency protects from sepsis-induced long-term cognitive deficits. J Neurosci. 2009 Nov 11; 29(45):14177-84.
    View in: PubMed
    Score: 0.066
  66. Semmler A, Hermann S, Mormann F, Weberpals M, Paxian SA, Okulla T, Sch?fers M, Kummer MP, Klockgether T, Heneka MT. Sepsis causes neuroinflammation and concomitant decrease of cerebral metabolism. J Neuroinflammation. 2008 Sep 15; 5:38.
    View in: PubMed
    Score: 0.061
  67. Sastre M, Klockgether T, Heneka MT. Contribution of inflammatory processes to Alzheimer's disease: molecular mechanisms. Int J Dev Neurosci. 2006 Apr-May; 24(2-3):167-76.
    View in: PubMed
    Score: 0.051
  68. Heneka MT, Ramanathan M, Jacobs AH, Dumitrescu-Ozimek L, Bilkei-Gorzo A, Debeir T, Sastre M, Galldiks N, Zimmer A, Hoehn M, Heiss WD, Klockgether T, Staufenbiel M. Locus ceruleus degeneration promotes Alzheimer pathogenesis in amyloid precursor protein 23 transgenic mice. J Neurosci. 2006 Feb 01; 26(5):1343-54.
    View in: PubMed
    Score: 0.051
  69. Semmler A, Okulla T, Sastre M, Dumitrescu-Ozimek L, Heneka MT. Systemic inflammation induces apoptosis with variable vulnerability of different brain regions. J Chem Neuroanat. 2005 Oct; 30(2-3):144-57.
    View in: PubMed
    Score: 0.050
  70. Eberhard J, Henning L, F?lle L, Kn?pper K, B?hringer J, Graelmann FJ, H?nschke L, Kenzler J, Brosseron F, Heneka MT, Domingos AI, Eyerich S, Lochner M, Weighardt H, Bedner P, Steinh?user C, F?rster I. Ablation of CCL17-positive hippocampal neurons induces inflammation-dependent epilepsy. Epilepsia. 2025 Feb; 66(2):554-568.
    View in: PubMed
    Score: 0.047
  71. Kloske CM, Barnum CJ, Batista AF, Bradshaw EM, Brickman AM, Bu G, Dennison J, Gearon MD, Goate AM, Haass C, Heneka MT, Hu WT, Huggins LKL, Jones NS, Koldamova R, Lemere CA, Liddelow SA, Marcora E, Marsh SE, Nielsen HM, Petersen KK, Petersen M, Pi?a-Escudero SD, Qiu WQ, Quiroz YT, Reiman E, Sexton C, Tansey MG, Tcw J, Teunissen CE, Tijms BM, van der Kant R, Wallings R, Weninger SC, Wharton W, Wilcock DM, Wishard TJ, Worley SL, Zetterberg H, Carrillo MC. APOE and immunity: Research highlights. Alzheimers Dement. 2023 06; 19(6):2677-2696.
    View in: PubMed
    Score: 0.042
  72. Henning L, Antony H, Breuer A, M?ller J, Seifert G, Audinat E, Singh P, Brosseron F, Heneka MT, Steinh?user C, Bedner P. Reactive microglia are the major source of tumor necrosis factor alpha and contribute to astrocyte dysfunction and acute seizures in experimental temporal lobe epilepsy. Glia. 2023 02; 71(2):168-186.
    View in: PubMed
    Score: 0.040
  73. Perea JR, Bol?s M, Cuadros R, Garc?a E, Garc?a-Escudero V, Hern?ndez F, McManus RM, Heneka MT, Avila J. p38 Inhibition Decreases Tau Toxicity in Microglia and Improves Their Phagocytic Function. Mol Neurobiol. 2022 Mar; 59(3):1632-1648.
    View in: PubMed
    Score: 0.038
  74. Jiang S, Maphis NM, Binder J, Chisholm D, Weston L, Duran W, Peterson C, Zimmerman A, Mandell MA, Jett SD, Bigio E, Geula C, Mellios N, Weick JP, Rosenberg GA, Latz E, Heneka MT, Bhaskar K. Proteopathic tau primes and activates interleukin-1? via myeloid-cell-specific MyD88- and NLRP3-ASC-inflammasome pathway. Cell Rep. 2021 09 21; 36(12):109720.
    View in: PubMed
    Score: 0.038
  75. Ribon M, Leone C, Chiot A, Berriat F, Rampanana M, Cottin J, Bohl D, Millecamps S, Lobsiger CS, Heneka MT, Boill?e S. Deletion of the inflammatory S100-A9/MRP14 protein does not influence survival in hSOD1G93A ALS mice. Neurobiol Aging. 2021 05; 101:181-186.
    View in: PubMed
    Score: 0.036
  76. Mantile F, Capasso A, Villacampa N, Donnini M, Liguori GL, Constantin G, De Berardinis P, Heneka MT, Prisco A. Vaccination with (1-11)E2 in alum efficiently induces an antibody response to ?-amyloid without affecting brain ?-amyloid load and microglia activation in 3xTg mice. Aging Clin Exp Res. 2021 May; 33(5):1383-1387.
    View in: PubMed
    Score: 0.033
  77. Krauthausen M, Kummer MP, Zimmermann J, Reyes-Irisarri E, Terwel D, Bulic B, Heneka MT, M?ller M. CXCR3 promotes plaque formation and behavioral deficits in an Alzheimer's disease model. J Clin Invest. 2015 Jan; 125(1):365-78.
    View in: PubMed
    Score: 0.023
  78. Ambr?e O, Leimer U, Herring A, G?rtz N, Sachser N, Heneka MT, Paulus W, Keyvani K. Reduction of amyloid angiopathy and Abeta plaque burden after enriched housing in TgCRND8 mice: involvement of multiple pathways. Am J Pathol. 2006 Aug; 169(2):544-52.
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    Score: 0.013
  79. Kalinin S, Gavrilyuk V, Polak PE, Vasser R, Zhao J, Heneka MT, Feinstein DL. Noradrenaline deficiency in brain increases beta-amyloid plaque burden in an animal model of Alzheimer's disease. Neurobiol Aging. 2007 Aug; 28(8):1206-14.
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    Score: 0.013
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.