Michael Heneka to Alzheimer Disease
This is a "connection" page, showing publications Michael Heneka has written about Alzheimer Disease.
Connection Strength
26.677
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Galgani A, Mary A, Lombardo F, Martini N, Scotto M, Tognoni G, Siciliano G, Ceravolo R, Giorgi FS, Heneka MT. Locus coeruleus integrity correlates with plasma soluble Axl levels in Alzheimer's disease patients. Alzheimers Dement. 2025 Jul; 21(7):e70434.
Score: 0.577
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Villacampa N, Sarlus H, Martorell P, Bhalla K, Castro-Gomez S, Vieira-Saecker A, Slutzkin I, H?ndler K, Venegas C, McManus R, Ulas T, Beyer M, Segal E, Heneka MT. Proliferating Microglia Exhibit Unique Transcriptional and Functional Alterations in Alzheimer's Disease. ASN Neuro. 2025; 17(1):2506406.
Score: 0.572
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Heneka MT, Gauthier S, Chandekar SA, Hviid Hahn-Pedersen J, Bentsen MA, Zetterberg H. Neuroinflammatory fluid biomarkers in patients with Alzheimer's disease: a systematic literature review. Mol Psychiatry. 2025 Jun; 30(6):2783-2798.
Score: 0.564
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McManus RM, Komes MP, Griep A, Santarelli F, Schwartz S, Ram?n Perea J, Schlachetzki JCM, Bouvier DS, Khalil MA, Lauterbach MA, Heinemann L, Schl?ter T, Pour MS, Lovotti M, Stahl R, Duthie F, Rodr?guez-Alc?zar JF, Schmidt SV, Spitzer J, Noori P, Maillo A, Boettcher A, Herron B, McConville J, Gomez-Cabrero D, Tegn?r J, Glass CK, Hiller K, Latz E, Heneka MT. NLRP3-mediated glutaminolysis controls microglial phagocytosis to promote Alzheimer's disease progression. Immunity. 2025 Feb 11; 58(2):326-343.e11.
Score: 0.561
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Heneka MT, van der Flier WM, Jessen F, Hoozemanns J, Thal DR, Boche D, Brosseron F, Teunissen C, Zetterberg H, Jacobs AH, Edison P, Ramirez A, Cruchaga C, Lambert JC, Laza AR, Sanchez-Mut JV, Fischer A, Castro-Gomez S, Stein TD, Kleineidam L, Wagner M, Neher JJ, Cunningham C, Singhrao SK, Prinz M, Glass CK, Schlachetzki JCM, Butovsky O, Kleemann K, De Jaeger PL, Scheiblich H, Brown GC, Landreth G, Moutinho M, Grutzendler J, Gomez-Nicola D, McManus RM, Andreasson K, Ising C, Karabag D, Baker DJ, Liddelow SA, Verkhratsky A, Tansey M, Monsonego A, Aigner L, Doroth?e G, Nave KA, Simons M, Constantin G, Rosenzweig N, Pascual A, Petzold GC, Kipnis J, Venegas C, Colonna M, Walter J, Tenner AJ, O'Banion MK, Steinert JR, Feinstein DL, Sastre M, Bhaskar K, Hong S, Schafer DP, Golde T, Ransohoff RM, Morgan D, Breitner J, Mancuso R, Riechers SP. Neuroinflammation in Alzheimer disease. Nat Rev Immunol. 2025 May; 25(5):321-352.
Score: 0.555
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Heneka MT, Morgan D, Jessen F. Passive anti-amyloid ? immunotherapy in Alzheimer's disease-opportunities and challenges. Lancet. 2024 11 30; 404(10468):2198-2208.
Score: 0.552
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Botella Lucena P, Heneka MT. Inflammatory aspects of Alzheimer's disease. Acta Neuropathol. 2024 08 28; 148(1):31.
Score: 0.544
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Mary A, Mancuso R, Heneka MT. Immune Activation in Alzheimer Disease. Annu Rev Immunol. 2024 06; 42(1):585-613.
Score: 0.536
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Heneka MT. TREM1 is the new kid on the block for the aging-associated innate immune response and Alzheimer's disease. Nat Immunol. 2024 Jun; 25(6):938-940.
Score: 0.535
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Heneka M, Gauthier S, Chandekar SA, Hahn-Pedersen JH, Bentsen M, Zetterberg H. The Role of Neuroinflammation in Alzheimer's Disease: A Systematic Literature Review (P7-9.013). Neurology. 2024 Apr 09; 102(7_supplement_1):3344.
Score: 0.530
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Brown GC, Heneka MT. The endotoxin hypothesis of Alzheimer's disease. Mol Neurodegener. 2024 Apr 01; 19(1):30.
Score: 0.529
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Heneka MT. ApoE4 makes microglia trem2bling. Neuron. 2023 01 18; 111(2):142-144.
Score: 0.487
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Teipel SJ, Dyrba M, Ballarini T, Brosseron F, Bruno D, Buerger K, Cosma NC, Dechent P, Dobisch L, D?zel E, Ewers M, Fliessbach K, Haynes JD, Janowitz D, Kilimann I, Laske C, Maier F, Metzger CD, Munk MH, Peters O, Pomara N, Preis L, Priller J, Ram?rez A, Roy N, Scheffler K, Schneider A, Schott BH, Spottke A, Spruth EJ, Wagner M, Wiltfang J, Jessen F, Heneka MT. Association of Cholinergic Basal Forebrain Volume and Functional Connectivity with Markers of Inflammatory Response in the Alzheimer's Disease Spectrum. J Alzheimers Dis. 2022; 85(3):1267-1282.
Score: 0.453
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Kummer MP, Ising C, Kummer C, Sarlus H, Griep A, Vieira-Saecker A, Schwartz S, Halle A, Br?ckner M, H?ndler K, Schultze JL, Beyer M, Latz E, Heneka MT. Microglial PD-1 stimulation by astrocytic PD-L1 suppresses neuroinflammation and Alzheimer's disease pathology. EMBO J. 2021 12 15; 40(24):e108662.
Score: 0.450
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Bettcher BM, Tansey MG, Doroth?e G, Heneka MT. Peripheral and central immune system crosstalk in Alzheimer disease - a research prospectus. Nat Rev Neurol. 2021 11; 17(11):689-701.
Score: 0.443
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Brosseron F, Kleemann K, Kolbe CC, Santarelli F, Castro-Gomez S, Tacik P, Latz E, Jessen F, Heneka MT. Interrelations of Alzheimer?s disease candidate biomarkers neurogranin, fatty acid-binding protein 3 and ferritin to neurodegeneration and neuroinflammation. J Neurochem. 2021 06; 157(6):2210-2224.
Score: 0.414
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Villacampa N, Heneka MT. Microglia in Alzheimer's disease: Local heroes! J Exp Med. 2020 04 06; 217(4).
Score: 0.401
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McManus RM, Heneka MT. T cells in Alzheimer's disease: space invaders. Lancet Neurol. 2020 04; 19(4):285-287.
Score: 0.400
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Heneka MT. An immune-cell signature marks the brain in Alzheimer's disease. Nature. 2020 01; 577(7790):322-323.
Score: 0.394
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Venegas C, Heneka MT. Inflammasome-mediated innate immunity in Alzheimer's disease. FASEB J. 2019 12; 33(12):13075-13084.
Score: 0.390
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Wijasa TS, Sylvester M, Brocke-Ahmadinejad N, Schwartz S, Santarelli F, Gieselmann V, Klockgether T, Brosseron F, Heneka MT. Quantitative proteomics of synaptosome S-nitrosylation in Alzheimer's disease. J Neurochem. 2020 03; 152(6):710-726.
Score: 0.389
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Castro-Gomez S, Binder J, Heneka MT. [Neuroinflammation as motor of Alzheimer's disease]. Nervenarzt. 2019 Sep; 90(9):898-906.
Score: 0.385
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Tejera D, Mercan D, Sanchez-Caro JM, Hanan M, Greenberg D, Soreq H, Latz E, Golenbock D, Heneka MT. Systemic inflammation impairs microglial A? clearance through NLRP3 inflammasome. EMBO J. 2019 09 02; 38(17):e101064.
Score: 0.383
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Herrera-Rivero M, Santarelli F, Brosseron F, Kummer MP, Heneka MT. Dysregulation of TLR5 and TAM Ligands in the Alzheimer's Brain as Contributors to Disease Progression. Mol Neurobiol. 2019 Sep; 56(9):6539-6550.
Score: 0.372
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Tejera D, Heneka MT. In Vivo Phagocytosis Analysis of Amyloid Beta. Methods Mol Biol. 2019; 2034:287-292.
Score: 0.368
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Brosseron F, Trasch?tz A, Widmann CN, Kummer MP, Tacik P, Santarelli F, Jessen F, Heneka MT. Characterization and clinical use of inflammatory cerebrospinal fluid protein markers in Alzheimer's disease. Alzheimers Res Ther. 2018 02 26; 10(1):25.
Score: 0.347
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Dansokho C, Heneka MT. Neuroinflammatory responses in Alzheimer's disease. J Neural Transm (Vienna). 2018 05; 125(5):771-779.
Score: 0.342
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Venegas C, Kumar S, Franklin BS, Dierkes T, Brinkschulte R, Tejera D, Vieira-Saecker A, Schwartz S, Santarelli F, Kummer MP, Griep A, Gelpi E, Beilharz M, Riedel D, Golenbock DT, Geyer M, Walter J, Latz E, Heneka MT. Microglia-derived ASC specks cross-seed amyloid-? in Alzheimer's disease. Nature. 2017 12 20; 552(7685):355-361.
Score: 0.342
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Sarlus H, Heneka MT. Microglia in Alzheimer's disease. J Clin Invest. 2017 Sep 01; 127(9):3240-3249.
Score: 0.335
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McManus RM, Heneka MT. Role of neuroinflammation in neurodegeneration: new insights. Alzheimers Res Ther. 2017 Mar 04; 9(1):14.
Score: 0.324
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Heneka MT. Inflammasome activation and innate immunity in Alzheimer's disease. Brain Pathol. 2017 03; 27(2):220-222.
Score: 0.324
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Venegas C, Heneka MT. Danger-associated molecular patterns in Alzheimer's disease. J Leukoc Biol. 2017 01; 101(1):87-98.
Score: 0.316
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Tejera D, Heneka MT. Microglia in Alzheimer's disease: the good, the bad and the ugly. Curr Alzheimer Res. 2016; 13(4):370-80.
Score: 0.299
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Heneka MT, Carson MJ, El Khoury J, Landreth GE, Brosseron F, Feinstein DL, Jacobs AH, Wyss-Coray T, Vitorica J, Ransohoff RM, Herrup K, Frautschy SA, Finsen B, Brown GC, Verkhratsky A, Yamanaka K, Koistinaho J, Latz E, Halle A, Petzold GC, Town T, Morgan D, Shinohara ML, Perry VH, Holmes C, Bazan NG, Brooks DJ, Hunot S, Joseph B, Deigendesch N, Garaschuk O, Boddeke E, Dinarello CA, Breitner JC, Cole GM, Golenbock DT, Kummer MP. Neuroinflammation in Alzheimer's disease. Lancet Neurol. 2015 Apr; 14(4):388-405.
Score: 0.283
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Heneka MT, Golenbock DT, Latz E. Innate immunity in Alzheimer's disease. Nat Immunol. 2015 Mar; 16(3):229-36.
Score: 0.282
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Brosseron F, Krauthausen M, Kummer M, Heneka MT. Body fluid cytokine levels in mild cognitive impairment and Alzheimer's disease: a comparative overview. Mol Neurobiol. 2014 Oct; 50(2):534-44.
Score: 0.263
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Heneka MT, Kummer MP, Stutz A, Delekate A, Schwartz S, Vieira-Saecker A, Griep A, Axt D, Remus A, Tzeng TC, Gelpi E, Halle A, Korte M, Latz E, Golenbock DT. NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice. Nature. 2013 Jan 31; 493(7434):674-8.
Score: 0.242
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Yamanaka M, Ishikawa T, Griep A, Axt D, Kummer MP, Heneka MT. PPAR?/RXRa-induced and CD36-mediated microglial amyloid-? phagocytosis results in cognitive improvement in amyloid precursor protein/presenilin 1 mice. J Neurosci. 2012 Nov 28; 32(48):17321-31.
Score: 0.241
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Kummer MP, H?lsmann C, Hermes M, Axt D, Heneka MT. Nitric oxide decreases the enzymatic activity of insulin degrading enzyme in APP/PS1 mice. J Neuroimmune Pharmacol. 2012 Mar; 7(1):165-72.
Score: 0.227
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Rey NL, Jardanhazi-Kurutz D, Terwel D, Kummer MP, Jourdan F, Didier A, Heneka MT. Locus coeruleus degeneration exacerbates olfactory deficits in APP/PS1 transgenic mice. Neurobiol Aging. 2012 Feb; 33(2):426.e1-11.
Score: 0.210
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Heneka MT, O'Banion MK, Terwel D, Kummer MP. Neuroinflammatory processes in Alzheimer's disease. J Neural Transm (Vienna). 2010 Aug; 117(8):919-47.
Score: 0.204
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Heneka MT, Nadrigny F, Regen T, Martinez-Hernandez A, Dumitrescu-Ozimek L, Terwel D, Jardanhazi-Kurutz D, Walter J, Kirchhoff F, Hanisch UK, Kummer MP. Locus ceruleus controls Alzheimer's disease pathology by modulating microglial functions through norepinephrine. Proc Natl Acad Sci U S A. 2010 Mar 30; 107(13):6058-63.
Score: 0.200
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Landreth G, Jiang Q, Mandrekar S, Heneka M. PPARgamma agonists as therapeutics for the treatment of Alzheimer's disease. Neurotherapeutics. 2008 Jul; 5(3):481-9.
Score: 0.178
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Heneka MT, O'Banion MK. Inflammatory processes in Alzheimer's disease. J Neuroimmunol. 2007 Mar; 184(1-2):69-91.
Score: 0.160
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Sastre M, Klockgether T, Heneka MT. Contribution of inflammatory processes to Alzheimer's disease: molecular mechanisms. Int J Dev Neurosci. 2006 Apr-May; 24(2-3):167-76.
Score: 0.150
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Heneka MT, Ramanathan M, Jacobs AH, Dumitrescu-Ozimek L, Bilkei-Gorzo A, Debeir T, Sastre M, Galldiks N, Zimmer A, Hoehn M, Heiss WD, Klockgether T, Staufenbiel M. Locus ceruleus degeneration promotes Alzheimer pathogenesis in amyloid precursor protein 23 transgenic mice. J Neurosci. 2006 Feb 01; 26(5):1343-54.
Score: 0.150
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H?ll M, Berger M, Heneka M. Disease-modifying therapies in Alzheimer's disease: how far have we come? Drugs. 2006; 66(16):2075-93.
Score: 0.149
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Li Q, Koehler S, Koenig A, Dyrba M, Mallik E, Linz N, Priller J, Spruth E, Altenstein S, Wiltfang J, Zerr I, Bartels C, Maier F, Rostamzadeh A, Duezel E, Glanz W, Incesoy EI, Butryn M, Laske C, Sodenkamp S, Munk MH, Falkenburger B, Osterrath A, Kilimann I, Stark M, Kleineidam L, Heneka MT, Spottke A, Wagner M, Jessen F, Petzold GC, Levin F, Teipel S. Associations between digital speech features of automated cognitive tasks and trajectories of brain atrophy and cognitive decline in early Alzheimer's disease. J Alzheimers Dis. 2025 Sep; 107(1):154-169.
Score: 0.145
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Heneka MT, Sastre M, Dumitrescu-Ozimek L, Hanke A, Dewachter I, Kuiperi C, O'Banion K, Klockgether T, Van Leuven F, Landreth GE. Acute treatment with the PPARgamma agonist pioglitazone and ibuprofen reduces glial inflammation and Abeta1-42 levels in APPV717I transgenic mice. Brain. 2005 Jun; 128(Pt 6):1442-53.
Score: 0.142
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Kuhn E, Klinger HM, Amariglio RE, Wagner M, Jessen F, D?zel E, Heneka MT, Ch?telat G, Rentz DM, Sperling RA, Ebenau JL, Butterbrod E, Van Der Flier WM, Sikkes SAM, Teunnissen CE, Van Harten AC, Van De Giessen EM, Rami L, Tort A, S?nchez Benavides G, Gifford KA, Van Hulle C, Buckley RF. SCD-plus features and AD biomarkers in cognitively unimpaired samples: A meta-analytic approach for nine cohort studies. Alzheimers Dement. 2025 May; 21(5):e14307.
Score: 0.141
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Schneider LS, Freiesleben SD, van Breukelen G, Wang X, Brosseron F, Heneka MT, Teipel S, Kleineidam L, Stark M, Roy-Kluth N, Wagner M, Spottke A, Schmid M, Roeske S, Laske C, Munk MH, Perneczky R, Rauchmann BS, Buerger K, Janowitz D, D?zel E, Glanz W, Jessen F, Rostamzadeh A, Wiltfang J, Bartels C, Kilimann I, Schneider A, Fliessbach K, Priller J, Spruth EJ, Hellmann-Regen J, Peters O. Linking higher amyloid beta 1-38 (A?(1-38)) levels to reduced Alzheimer's disease progression risk. Alzheimers Dement. 2025 Feb; 21(2):e14545.
Score: 0.140
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Kloske CM, Mahinrad S, Barnum CJ, Batista AF, Bradshaw EM, Butts B, Carrillo MC, Chakrabarty P, Chen X, Craft S, Da Mesquita S, Dabin LC, Devanand D, Duran-Laforet V, Elyaman W, Evans EE, Fitzgerald-Bocarsly P, Foley KE, Harms AS, Heneka MT, Hong S, Huang YA, Jackvony S, Lai L, Guen YL, Lemere CA, Liddelow SA, Martin-Pe?a A, Orr AG, Quintana FJ, Ramey GD, Rexach JE, Rizzo SJS, Sexton C, Tang AS, Torrellas JG, Tsai AP, van Olst L, Walker KA, Wharton W, Tansey MG, Wilcock DM. Advancements in Immunity and Dementia Research: Highlights from the 2023 AAIC Advancements: Immunity Conference. Alzheimers Dement. 2025 Jan; 21(1):e14291.
Score: 0.139
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Schrempel S, Kottwitz AK, Piechotta A, Gnoth K, B?schgens L, Hartlage-R?bsamen M, Morawski M, Schenk M, Kleinschmidt M, Serrano GE, Beach TG, Rostagno A, Ghiso J, Heneka MT, Walter J, Wirths O, Schilling S, Ro?ner S. Identification of isoAsp7-A? as a major A? variant in Alzheimer's disease, dementia with Lewy bodies and vascular dementia. Acta Neuropathol. 2024 12 03; 148(1):78.
Score: 0.139
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Stark M, Wagner M, Kuhn E, B?rger K, D?zel E, Hellmann-Regen J, Heneka MT, Laske C, Perneczky R, Peters O, Priller J, Schmid M, Schneider A, Spottke A, Teipel S, Wiltfang J, Jessen F, Kleineidam L. Clinical Manifestations. Alzheimers Dement. 2024 Dec; 20 Suppl 3:e091377.
Score: 0.139
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Vockert N, Machts J, Kleineidam L, Nemali A, Incesoy EI, Bernal J, Sch?tze H, Yakupov R, Peters O, Gref D, Schneider LS, Preis L, Priller J, Spruth EJ, Altenstein S, Schneider A, Fliessbach K, Wiltfang J, Rostamzadeh A, Glanz W, Teipel S, Kilimann I, Goerss D, Laske C, Munk MH, Spottke A, Roy N, Heneka MT, Brosseron F, Wagner M, Wolfsgruber S, Dobisch L, Dechent P, Hetzer S, Scheffler K, Zeidman P, Stern Y, Schott BH, Jessen F, D?zel E, Maass A, Ziegler G. Cognitive reserve against Alzheimer's pathology is linked to brain activity during memory formation. Nat Commun. 2024 11 13; 15(1):9815.
Score: 0.138
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Soch J, Richter A, Kizilirmak JM, Sch?tze H, Ziegler G, Altenstein S, Brosseron F, Dechent P, Fliessbach K, Freiesleben SD, Glanz W, Gref D, Heneka MT, Hetzer S, Incesoy EI, Kilimann I, Kimmich O, Kleineidam L, Kuhn E, Laske C, Lohse A, L?sebrink F, Munk MH, Peters O, Preis L, Priller J, Ramirez A, Roeske S, Rostamzadeh A, Roy-Kluth N, Scheffler K, Schmid M, Schneider A, Spottke A, Spruth EJ, Teipel S, Wiltfang J, Jessen F, Wagner M, D?zel E, Schott BH. Single-value brain activity scores reflect both severity and risk across the Alzheimer's continuum. Brain. 2024 Nov 04; 147(11):3789-3803.
Score: 0.138
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Menze I, Bernal J, Kaya P, Aki ?, Pfister M, Geisend?rfer J, Yakupov R, Coello RD, Vald?s-Hern?ndez MDC, Heneka MT, Brosseron F, Schmid MC, Glanz W, Incesoy EI, Butryn M, Rostamzadeh A, Meiberth D, Peters O, Preis L, Lammerding D, Gref D, Priller J, Spruth EJ, Altenstein S, Lohse A, Hetzer S, Schneider A, Fliessbach K, Kimmich O, Vogt IR, Wiltfang J, Bartels C, Schott BH, Hansen N, Dechent P, Buerger K, Janowitz D, Perneczky R, Rauchmann BS, Teipel S, Kilimann I, Goerss D, Laske C, Munk MH, Sanzenbacher C, Hinderer P, Scheffler K, Spottke A, Roy-Kluth N, L?sebrink F, Neumann K, Wardlaw J, Jessen F, Schreiber S, D?zel E, Ziegler G. Perivascular space enlargement accelerates in ageing and Alzheimer's disease pathology: evidence from a three-year longitudinal multicentre study. Alzheimers Res Ther. 2024 Oct 31; 16(1):242.
Score: 0.138
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Lista S, Imbimbo BP, Grasso M, Fidilio A, Emanuele E, Minoretti P, L?pez-Ortiz S, Mart?n-Hern?ndez J, Gabelle A, Caruso G, Malaguti M, Melchiorri D, Santos-Lozano A, Imbimbo C, Heneka MT, Caraci F. Tracking neuroinflammatory biomarkers in Alzheimer's disease: a strategy for individualized therapeutic approaches? J Neuroinflammation. 2024 Jul 30; 21(1):187.
Score: 0.135
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Baumeister H, Vogel JW, Insel PS, Kleineidam L, Wolfsgruber S, Stark M, Gellersen HM, Yakupov R, Schmid MC, L?sebrink F, Brosseron F, Ziegler G, Freiesleben SD, Preis L, Schneider LS, Spruth EJ, Altenstein S, Lohse A, Fliessbach K, Vogt IR, Bartels C, Schott BH, Rostamzadeh A, Glanz W, Incesoy EI, Butryn M, Janowitz D, Rauchmann BS, Kilimann I, Goerss D, Munk MH, Hetzer S, Dechent P, Ewers M, Scheffler K, Wuestefeld A, Strandberg O, van Westen D, Mattsson-Carlgren N, Janelidze S, Stomrud E, Palmqvist S, Spottke A, Laske C, Teipel S, Perneczky R, Buerger K, Schneider A, Priller J, Peters O, Ramirez A, Wiltfang J, Heneka MT, Wagner M, D?zel E, Jessen F, Hansson O, Berron D. A generalizable data-driven model of atrophy heterogeneity and progression in memory clinic settings. Brain. 2024 Jul 05; 147(7):2400-2413.
Score: 0.135
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Vogelgsang J, Hansen N, Stark M, Wagner M, Klafki H, Morgado BM, Jahn-Brodmann A, Schott B, Esselmann H, Bauer C, Schuchhardt J, Kleineidam L, Wolfsgruber S, Peters O, Schneider LS, Wang X, Menne F, Priller J, Spruth E, Altenstein S, Lohse A, Schneider A, Fliessbach K, Vogt I, Bartels C, Jessen F, Rostamzadeh A, Duezel E, Glanz W, Incesoy E, Butryn M, Buerger K, Janowitz D, Ewers M, Perneczky R, Rauchmann B, Guersel S, Teipel S, Kilimann I, Goerss D, Laske C, Munk M, Sanzenbacher C, Spottke A, Roy-Kluth N, Heneka M, Brosseron F, Ramierez A, Schmid M, Wiltfang J. Plasma amyloid beta X-42/X-40 ratio and cognitive decline in suspected early and preclinical Alzheimer's disease. Alzheimers Dement. 2024 08; 20(8):5132-5142.
Score: 0.134
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Deike K, Decker A, Scheyhing P, Harten J, Zimmermann N, Paech D, Peters O, Freiesleben SD, Schneider LS, Preis L, Priller J, Spruth E, Altenstein S, Lohse A, Fliessbach K, Kimmich O, Wiltfang J, Bartels C, Hansen N, Jessen F, Rostamzadeh A, D?zel E, Glanz W, Incesoy EI, Butryn M, Buerger K, Janowitz D, Ewers M, Perneczky R, Rauchmann BS, Teipel S, Kilimann I, Goerss D, Laske C, Munk MH, Spottke A, Roy N, Wagner M, Roeske S, Heneka MT, Brosseron F, Ramirez A, Dobisch L, Wolfsgruber S, Kleineidam L, Yakupov R, Stark M, Schmid MC, Berger M, Hetzer S, Dechent P, Scheffler K, Petzold GC, Schneider A, Effland A, Radbruch A. Machine Learning-Based Perivascular Space Volumetry in Alzheimer Disease. Invest Radiol. 2024 Sep 01; 59(9):667-676.
Score: 0.133
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Ferguson CM, Hildebrand S, Godinho BMDC, Buchwald J, Echeverria D, Coles A, Grigorenko A, Vangjeli L, Sousa J, McHugh N, Hassler M, Santarelli F, Heneka MT, Rogaev E, Khvorova A. Silencing Apoe with divalent-siRNAs improves amyloid burden and activates immune response pathways in Alzheimer's disease. Alzheimers Dement. 2024 04; 20(4):2632-2652.
Score: 0.131
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Talavera And?jar B, Mary A, Venegas C, Cheng T, Zaslavsky L, Bolton EE, Heneka MT, Schymanski EL. Can Small Molecules Provide Clues on Disease Progression in Cerebrospinal Fluid from Mild Cognitive Impairment and Alzheimer's Disease Patients? Environ Sci Technol. 2024 Mar 05; 58(9):4181-4192.
Score: 0.131
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Hayek D, Ziegler G, Kleineidam L, Brosseron F, Nemali A, Vockert N, Ravichandran KA, Betts MJ, Peters O, Schneider LS, Wang X, Priller J, Altenstein S, Schneider A, Fliessbach K, Wiltfang J, Bartels C, Rostamzadeh A, Glanz W, Buerger K, Janowitz D, Perneczky R, Rauchmann BS, Teipel S, Kilimann I, Laske C, Mengel D, Synofzik M, Munk MH, Spottke A, Roy N, Roeske S, Kuhn E, Ramirez A, Dobisch L, Schmid M, Berger M, Wolfsgruber S, Yakupov R, Hetzer S, Dechent P, Ewers M, Scheffler K, Schott BH, Schreiber S, Orellana A, de Rojas I, Marqui? M, Boada M, Sotolongo O, Gonz?lez PG, Puerta R, D?zel E, Jessen F, Wagner M, Ruiz A, Heneka MT, Maass A. Different inflammatory signatures based on CSF biomarkers relate to preserved or diminished brain structure and cognition. Mol Psychiatry. 2024 Apr; 29(4):992-1004.
Score: 0.130
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Sannemann L, Bartels C, Brosseron F, Buerger K, Fliessbach K, Freiesleben SD, Frommann I, Glanz W, Heneka MT, Janowitz D, Kilimann I, Kleineidam L, Lammerding D, Laske C, Munk MHJ, Perneczky R, Peters O, Priller J, Rauchmann BS, Rostamzadeh A, Roy-Kluth N, Schild AK, Schneider A, Schneider LS, Spottke A, Spruth EJ, Teipel S, Wagner M, Wiltfang J, Wolfsgruber S, Duezel E, Jessen F. Symptomatic Clusters Related to Amyloid Positivity in Cognitively Unimpaired Individuals. J Alzheimers Dis. 2024; 100(1):193-205.
Score: 0.130
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Stark M, Wolfsgruber S, Kleineidam L, Frommann I, Altenstein S, Bartels C, Brosseron F, Buerger K, Burow L, Butryn M, Ewers M, Fliessbach K, Gabelin T, Glanz W, Goerss D, Gref D, Hansen N, Heneka MT, Hinderer P, Incesoy EI, Janowitz D, Kilimann I, Kimmich O, Laske C, Munk MH, Perneczky R, Peters O, Preis L, Priller J, Rauchmann BS, Rostamzadeh A, Roy-Kluth N, Sanzenbacher C, Schneider A, Schott BH, Spottke A, Spruth EJ, Teipel S, Vogt IR, Wiltfang J, Duzel E, Jessen F, Wagner M. Relevance of Minor Neuropsychological Deficits in Patients With Subjective Cognitive Decline. Neurology. 2023 11 21; 101(21):e2185-e2196.
Score: 0.128
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Waschkies KF, Soch J, Darna M, Richter A, Altenstein S, Beyle A, Brosseron F, Buchholz F, Butryn M, Dobisch L, Ewers M, Fliessbach K, Gabelin T, Glanz W, Goerss D, Gref D, Janowitz D, Kilimann I, Lohse A, Munk MH, Rauchmann BS, Rostamzadeh A, Roy N, Spruth EJ, Dechent P, Heneka MT, Hetzer S, Ramirez A, Scheffler K, Buerger K, Laske C, Perneczky R, Peters O, Priller J, Schneider A, Spottke A, Teipel S, D?zel E, Jessen F, Wiltfang J, Schott BH, Kizilirmak JM. Machine learning-based classification of Alzheimer's disease and its at-risk states using personality traits, anxiety, and depression. Int J Geriatr Psychiatry. 2023 10; 38(10):e6007.
Score: 0.128
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Walker KA, Le Page LM, Terrando N, Duggan MR, Heneka MT, Bettcher BM. The role of peripheral inflammatory insults in Alzheimer's disease: a review and research roadmap. Mol Neurodegener. 2023 06 05; 18(1):37.
Score: 0.125
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Nemy M, Dyrba M, Brosseron F, Buerger K, Dechent P, Dobisch L, Ewers M, Fliessbach K, Glanz W, Goerss D, Heneka MT, Hetzer S, Incesoy EI, Janowitz D, Kilimann I, Laske C, Maier F, Munk MH, Perneczky R, Peters O, Preis L, Priller J, Rauchmann BS, R?ske S, Roy N, Scheffler K, Schneider A, Schott BH, Spottke A, Spruth EJ, Wagner M, Wiltfang J, Yakupov R, Eriksdotter M, Westman E, Stepankova O, Vyslouzilova L, D?zel E, Jessen F, Teipel SJ, Ferreira D. Cholinergic white matter pathways along the Alzheimer's disease continuum. Brain. 2023 05 02; 146(5):2075-2088.
Score: 0.124
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Kloske CM, Barnum CJ, Batista AF, Bradshaw EM, Brickman AM, Bu G, Dennison J, Gearon MD, Goate AM, Haass C, Heneka MT, Hu WT, Huggins LKL, Jones NS, Koldamova R, Lemere CA, Liddelow SA, Marcora E, Marsh SE, Nielsen HM, Petersen KK, Petersen M, Pi?a-Escudero SD, Qiu WQ, Quiroz YT, Reiman E, Sexton C, Tansey MG, Tcw J, Teunissen CE, Tijms BM, van der Kant R, Wallings R, Weninger SC, Wharton W, Wilcock DM, Wishard TJ, Worley SL, Zetterberg H, Carrillo MC. APOE and immunity: Research highlights. Alzheimers Dement. 2023 06; 19(6):2677-2696.
Score: 0.123
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Heinzinger N, Maass A, Berron D, Yakupov R, Peters O, Fiebach J, Villringer K, Preis L, Priller J, Spruth EJ, Altenstein S, Schneider A, Fliessbach K, Wiltfang J, Bartels C, Jessen F, Maier F, Glanz W, Buerger K, Janowitz D, Perneczky R, Rauchmann BS, Teipel S, Killimann I, G?er? D, Laske C, Munk MH, Spottke A, Roy N, Heneka MT, Brosseron F, Dobisch L, Ewers M, Dechent P, Haynes JD, Scheffler K, Wolfsgruber S, Kleineidam L, Schmid M, Berger M, D?zel E, Ziegler G. Exploring the ATN classification system using brain morphology. Alzheimers Res Ther. 2023 03 13; 15(1):50.
Score: 0.123
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Yildirim Z, Delen F, Berron D, Baumeister H, Ziegler G, Sch?tze H, Glanz W, Dobisch L, Peters O, Freiesleben SD, Schneider LS, Priller J, Spruth EJ, Schneider A, Fliessbach K, Wiltfang J, Schott BH, Meiberth D, Buerger K, Janowitz D, Perneczky R, Rauchmann BS, Teipel S, Kilimann I, Laske C, Munk MH, Spottke A, Roy N, Heneka M, Brosseron F, Wagner M, Roeske S, Ramirez A, Ewers M, Dechent P, Hetzer S, Scheffler K, Kleineidam L, Wolfsgruber S, Yakupov R, Schmid M, Berger M, Gurvit H, Jessen F, Duzel E. Brain reserve contributes to distinguishing preclinical Alzheimer's stages 1 and 2. Alzheimers Res Ther. 2023 02 28; 15(1):43.
Score: 0.123
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Brosseron F, Maass A, Kleineidam L, Ravichandran KA, Kolbe CC, Wolfsgruber S, Santarelli F, H?sler LM, McManus R, Ising C, R?ske S, Peters O, Cosma NC, Schneider LS, Wang X, Priller J, Spruth EJ, Altenstein S, Schneider A, Fliessbach K, Wiltfang J, Schott BH, Buerger K, Janowitz D, Dichgans M, Perneczky R, Rauchmann BS, Teipel S, Kilimann I, G?r? D, Laske C, Munk MH, D?zel E, Yakupow R, Dobisch L, Metzger CD, Glanz W, Ewers M, Dechent P, Haynes JD, Scheffler K, Roy N, Rostamzadeh A, Spottke A, Ramirez A, Mengel D, Synofzik M, Jucker M, Latz E, Jessen F, Wagner M, Heneka MT. Serum IL-6, sAXL, and YKL-40 as systemic correlates of reduced brain structure and function in Alzheimer's disease: results from the DELCODE study. Alzheimers Res Ther. 2023 01 12; 15(1):13.
Score: 0.122
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Ersoezlue E, Perneczky R, Tato M, Utecht J, Kurz C, H?ckert J, Guersel S, Burow L, Koller G, Stoecklein S, Keeser D, Papazov B, Totzke M, Ballarini T, Brosseron F, Buerger K, Dechent P, Dobisch L, Ewers M, Fliessbach K, Glanz W, Haynes JD, Heneka MT, Janowitz D, Kilimann I, Kleineidam L, Laske C, Maier F, Munk MH, Peters O, Priller J, Ramirez A, Roeske S, Roy N, Scheffler K, Schneider A, Schott BH, Spottke A, Spruth EJ, Teipel S, Unterfeld C, Wagner M, Wang X, Wiltfang J, Wolfsgruber S, Yakupov R, Duezel E, Jessen F, Rauchmann BS. A Residual Marker of Cognitive Reserve Is Associated with Resting-State Intrinsic Functional Connectivity Along the Alzheimer's Disease Continuum. J Alzheimers Dis. 2023; 92(3):925-940.
Score: 0.121
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Ersoezlue E, Rauchmann BS, Schneider-Axmann T, Wagner M, Ballarini T, Tato M, Utecht J, Kurz C, Papazov B, Guersel S, Burow L, Koller G, St?cklein S, Keeser D, Bartels C, Brosseron F, Buerger K, Cetindag AC, Dechent P, Dobisch L, Ewers M, Fliessbach K, Frommann I, Haynes JD, Heneka MT, Janowitz D, Kilimann I, Kleinedam L, Laske C, Maier F, Metzger CD, Munk MH, Peters O, Preis L, Priller J, Ramirez A, Roeske S, Roy N, Scheffler K, Schneider A, Spottke A, Spruth EJ, Teipel S, Wiltfang J, Wolfsgruber S, Yakupov R, Duezel E, Jessen F, Perneczky R. Lifelong experiences as a proxy of cognitive reserve moderate the association between connectivity and cognition in Alzheimer's disease. Neurobiol Aging. 2023 02; 122:33-44.
Score: 0.120
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Jansen IE, van der Lee SJ, Gomez-Fonseca D, de Rojas I, Dalmasso MC, Grenier-Boley B, Zettergren A, Mishra A, Ali M, Andrade V, Bellenguez C, Kleineidam L, K???kali F, Sung YJ, Tes? N, Vromen EM, Wightman DP, Alcolea D, Alegret M, Alvarez I, Amouyel P, Athanasiu L, Bahrami S, Bailly H, Belbin O, Bergh S, Bertram L, Biessels GJ, Blennow K, Blesa R, Boada M, Boland A, Buerger K, Carracedo ?, Cervera-Carles L, Chene G, Claassen JAHR, Debette S, Deleuze JF, de Deyn PP, Diehl-Schmid J, Djurovic S, Dols-Icardo O, Dufouil C, Duron E, D?zel E, Fladby T, Fortea J, Fr?lich L, Garc?a-Gonz?lez P, Garcia-Martinez M, Giegling I, Goldhardt O, Gobom J, Grimmer T, Haapasalo A, Hampel H, Hanon O, Hausner L, Heilmann-Heimbach S, Helisalmi S, Heneka MT, Hern?ndez I, Herukka SK, Holstege H, Jarholm J, Kern S, Knapskog AB, Koivisto AM, Kornhuber J, Kuulasmaa T, Lage C, Laske C, Leinonen V, Lewczuk P, Lle? A, de Munain AL, Lopez-Garcia S, Maier W, Marqui? M, Mol MO, Montrreal L, Moreno F, Moreno-Grau S, Nicolas G, N?then MM, Orellana A, P?lhaugen L, Papma JM, Pasquier F, Perneczky R, Peters O, Pijnenburg YAL, Popp J, Posthuma D, Pozueta A, Priller J, Puerta R, Quintela I, Ramakers I, Rodriguez-Rodriguez E, Rujescu D, Saltvedt I, Sanchez-Juan P, Scheltens P, Scherbaum N, Schmid M, Schneider A, Selb?k G, Selnes P, Shadrin A, Skoog I, Soininen H, T?rraga L, Teipel S, Tijms B, Tsolaki M, Van Broeckhoven C, Van Dongen J, van Swieten JC, Vandenberghe R, Vidal JS, Visser PJ, Vogelgsang J, Waern M, Wagner M, Wiltfang J, Wittens MMJ, Zetterberg H, Zulaica M, van Duijn CM, Bjerke M, Engelborghs S, Jessen F, Teunissen CE, Pastor P, Hiltunen M, Ingelsson M, Andreassen OA, Clarim?n J, Sleegers K, Ruiz A, Ramirez A, Cruchaga C, Lambert JC, van der Flier W. Genome-wide meta-analysis for Alzheimer's disease cerebrospinal fluid biomarkers. Acta Neuropathol. 2022 11; 144(5):821-842.
Score: 0.119
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Billette OV, Ziegler G, Aruci M, Sch?tze H, Kizilirmak JM, Richter A, Altenstein S, Bartels C, Brosseron F, Cardenas-Blanco A, Dahmen P, Dechent P, Dobisch L, Fliessbach K, Freiesleben SD, Glanz W, G?er? D, Haynes JD, Heneka MT, Kilimann I, Kimmich O, Kleineidam L, Laske C, Lohse A, Rostamzadeh A, Metzger C, Munk MH, Peters O, Preis L, Priller J, Scheffler K, Schneider A, Spottke A, Spruth EJ, Ramirez A, R?ske S, Roy N, Teipel S, Wagner M, Wiltfang J, Wolfsgruber S, Yakupov R, Zeidman P, Jessen F, Schott BH, D?zel E, Maass A. Novelty-Related fMRI Responses of Precuneus and Medial Temporal Regions in Individuals at Risk for Alzheimer Disease. Neurology. 2022 08 23; 99(8):e775-e788.
Score: 0.116
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D?zel E, Ziegler G, Berron D, Maass A, Sch?tze H, Cardenas-Blanco A, Glanz W, Metzger C, Dobisch L, Reuter M, Spottke A, Brosseron F, Fliessbach K, Heneka MT, Laske C, Peters O, Priller J, Spruth EJ, Ramirez A, Speck O, Schneider A, Teipel S, Kilimann I, Jens W, Schott BH, Preis L, Gref D, Maier F, Munk MH, Roy N, Ballarini T, Yakupov R, Haynes JD, Dechent P, Scheffler K, Wagner M, Jessen F. Amyloid pathology but not APOE e4 status is permissive for tau-related hippocampal dysfunction. Brain. 2022 05 24; 145(4):1473-1485.
Score: 0.116
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Jessen F, Wolfsgruber S, Kleineindam L, Spottke A, Altenstein S, Bartels C, Berger M, Brosseron F, Daamen M, Dichgans M, Dobisch L, Ewers M, Fenski F, Fliessbach K, Freiesleben SD, Glanz W, G?r? D, G?rsel S, Janowitz D, Kilimann I, Kobeleva X, Lohse A, Maier F, Metzger C, Munk M, Preis L, Sanzenbacher C, Spruth E, Rauchmann B, Vukovich R, Yakupov R, Weyrauch AS, Ziegler G, Schmid M, Laske C, Perneczky R, Schneider A, Wiltfang J, Teipel S, B?rger K, Priller J, Peters O, Ramirez A, Boecker H, Heneka MT, Wagner M, D?zel E. Subjective cognitive decline and stage 2 of Alzheimer disease in patients from memory centers. Alzheimers Dement. 2023 02; 19(2):487-497.
Score: 0.116
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Bellenguez C, K???kali F, Jansen IE, Kleineidam L, Moreno-Grau S, Amin N, Naj AC, Campos-Martin R, Grenier-Boley B, Andrade V, Holmans PA, Boland A, Damotte V, van der Lee SJ, Costa MR, Kuulasmaa T, Yang Q, de Rojas I, Bis JC, Yaqub A, Prokic I, Chapuis J, Ahmad S, Giedraitis V, Aarsland D, Garcia-Gonzalez P, Abdelnour C, Alarc?n-Mart?n E, Alcolea D, Alegret M, Alvarez I, ?lvarez V, Armstrong NJ, Tsolaki A, Ant?nez C, Appollonio I, Arcaro M, Archetti S, Pastor AA, Arosio B, Athanasiu L, Bailly H, Banaj N, Baquero M, Barral S, Beiser A, Pastor AB, Below JE, Benchek P, Benussi L, Berr C, Besse C, Bessi V, Binetti G, Bizarro A, Blesa R, Boada M, Boerwinkle E, Borroni B, Boschi S, Boss? P, Br?then G, Bressler J, Bresner C, Brodaty H, Brookes KJ, Brusco LI, Buiza-Rueda D, B?rger K, Burholt V, Bush WS, Calero M, Cantwell LB, Chene G, Chung J, Cuccaro ML, Carracedo ?, Cecchetti R, Cervera-Carles L, Charbonnier C, Chen HH, Chillotti C, Ciccone S, Claassen JAHR, Clark C, Conti E, Corma-G?mez A, Costantini E, Custodero C, Daian D, Dalmasso MC, Daniele A, Dardiotis E, Dartigues JF, de Deyn PP, de Paiva Lopes K, de Witte LD, Debette S, Deckert J, Del Ser T, Denning N, DeStefano A, Dichgans M, Diehl-Schmid J, Diez-Fairen M, Rossi PD, Djurovic S, Duron E, D?zel E, Dufouil C, Eiriksdottir G, Engelborghs S, Escott-Price V, Espinosa A, Ewers M, Faber KM, Fabrizio T, Nielsen SF, Fardo DW, Farotti L, Fenoglio C, Fern?ndez-Fuertes M, Ferrari R, Ferreira CB, Ferri E, Fin B, Fischer P, Fladby T, Flie?bach K, Fongang B, Fornage M, Fortea J, Foroud TM, Fostinelli S, Fox NC, Franco-Mac?as E, Bullido MJ, Frank-Garc?a A, Froelich L, Fulton-Howard B, Galimberti D, Garc?a-Alberca JM, Garc?a-Gonz?lez P, Garcia-Madrona S, Garcia-Ribas G, Ghidoni R, Giegling I, Giorgio G, Goate AM, Goldhardt O, Gomez-Fonseca D, Gonz?lez-P?rez A, Graff C, Grande G, Green E, Grimmer T, Gr?nblatt E, Grunin M, Gudnason V, Guetta-Baranes T, Haapasalo A, Hadjigeorgiou G, Haines JL, Hamilton-Nelson KL, Hampel H, Hanon O, Hardy J, Hartmann AM, Hausner L, Harwood J, Heilmann-Heimbach S, Helisalmi S, Heneka MT, Hern?ndez I, Herrmann MJ, Hoffmann P, Holmes C, Holstege H, Vilas RH, Hulsman M, Humphrey J, Biessels GJ, Jian X, Johansson C, Jun GR, Kastumata Y, Kauwe J, Kehoe PG, Kilander L, St?hlbom AK, Kivipelto M, Koivisto A, Kornhuber J, Kosmidis MH, Kukull WA, Kuksa PP, Kunkle BW, Kuzma AB, Lage C, Laukka EJ, Launer L, Lauria A, Lee CY, Lehtisalo J, Lerch O, Lle? A, Longstreth W, Lopez O, de Munain AL, Love S, L?wemark M, Luckcuck L, Lunetta KL, Ma Y, Mac?as J, MacLeod CA, Maier W, Mangialasche F, Spallazzi M, Marqui? M, Marshall R, Martin ER, Montes AM, Rodr?guez CM, Masullo C, Mayeux R, Mead S, Mecocci P, Medina M, Meggy A, Mehrabian S, Mendoza S, Men?ndez-Gonz?lez M, Mir P, Moebus S, Mol M, Molina-Porcel L, Montrreal L, Morelli L, Moreno F, Morgan K, Mosley T, N?then MM, Muchnik C, Mukherjee S, Nacmias B, Ngandu T, Nicolas G, Nordestgaard BG, Olaso R, Orellana A, Orsini M, Ortega G, Padovani A, Paolo C, Papenberg G, Parnetti L, Pasquier F, Pastor P, Peloso G, P?rez-Cord?n A, P?rez-Tur J, Pericard P, Peters O, Pijnenburg YAL, Pineda JA, Pi?ol-Ripoll G, Pisanu C, Polak T, Popp J, Posthuma D, Priller J, Puerta R, Quenez O, Quintela I, Thomassen JQ, R?bano A, Rainero I, Rajabli F, Ramakers I, Real LM, Reinders MJT, Reitz C, Reyes-Dumeyer D, Ridge P, Riedel-Heller S, Riederer P, Roberto N, Rodriguez-Rodriguez E, Rongve A, Allende IR, Rosende-Roca M, Royo JL, Rubino E, Rujescu D, S?ez ME, Sakka P, Saltvedt I, Sanabria ?, S?nchez-Arjona MB, Sanchez-Garcia F, Juan PS, S?nchez-Valle R, Sando SB, Sarnowski C, Satizabal CL, Scamosci M, Scarmeas N, Scarpini E, Scheltens P, Scherbaum N, Scherer M, Schmid M, Schneider A, Schott JM, Selb?k G, Seripa D, Serrano M, Sha J, Shadrin AA, Skrobot O, Slifer S, Snijders GJL, Soininen H, Solfrizzi V, Solomon A, Song Y, Sorbi S, Sotolongo-Grau O, Spalletta G, Spottke A, Squassina A, Stordal E, Tartan JP, T?rraga L, Tes? N, Thalamuthu A, Thomas T, et al. New insights into the genetic etiology of Alzheimer's disease and related dementias. Nat Genet. 2022 04; 54(4):412-436.
Score: 0.115
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Heneka MT, Galea E, Gavriluyk V, Dumitrescu-Ozimek L, Daeschner J, O'Banion MK, Weinberg G, Klockgether T, Feinstein DL. Noradrenergic depletion potentiates beta -amyloid-induced cortical inflammation: implications for Alzheimer's disease. J Neurosci. 2002 Apr 01; 22(7):2434-42.
Score: 0.115
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Jansen WJ, Janssen O, Tijms BM, Vos SJB, Ossenkoppele R, Visser PJ, Aarsland D, Alcolea D, Altomare D, von Arnim C, Baiardi S, Baldeiras I, Barthel H, Bateman RJ, Van Berckel B, Binette AP, Blennow K, Boada M, Boecker H, Bottlaender M, den Braber A, Brooks DJ, Van Buchem MA, Camus V, Carill JM, Cerman J, Chen K, Ch?telat G, Chipi E, Cohen AD, Daniels A, Delarue M, Didic M, Drzezga A, Dubois B, Eckerstr?m M, Ekblad LL, Engelborghs S, Epelbaum S, Fagan AM, Fan Y, Fladby T, Fleisher AS, Van der Flier WM, F?rster S, Fortea J, Frederiksen KS, Freund-Levi Y, Frings L, Frisoni GB, Fr?hlich L, Gabryelewicz T, Gertz HJ, Gill KD, Gkatzima O, G?mez-Tortosa E, Grimmer T, Guedj E, Habeck CG, Hampel H, Handels R, Hansson O, Hausner L, Hellwig S, Heneka MT, Herukka SK, Hildebrandt H, Hodges J, Hort J, Huang CC, Iriondo AJ, Itoh Y, Ivanoiu A, Jagust WJ, Jessen F, Johannsen P, Johnson KA, Kandimalla R, Kapaki EN, Kern S, Kilander L, Klimkowicz-Mrowiec A, Klunk WE, Koglin N, Kornhuber J, Kramberger MG, Kuo HC, Van Laere K, Landau SM, Landeau B, Lee DY, de Leon M, Leyton CE, Lin KJ, Lle? A, L?wenmark M, Madsen K, Maier W, Marcusson J, Marqui? M, Martinez-Lage P, Maserejian N, Mattsson N, de Mendon?a A, Meyer PT, Miller BL, Minatani S, Mintun MA, Mok VCT, Molinuevo JL, Morbelli SD, Morris JC, Mroczko B, Na DL, Newberg A, Nobili F, Nordberg A, Olde Rikkert MGM, de Oliveira CR, Olivieri P, Orellana A, Paraskevas G, Parchi P, Pardini M, Parnetti L, Peters O, Poirier J, Popp J, Prabhakar S, Rabinovici GD, Ramakers IH, Rami L, Reiman EM, Rinne JO, Rodrigue KM, Rodr?guez-Rodriguez E, Roe CM, Rosa-Neto P, Rosen HJ, Rot U, Rowe CC, R?ther E, Ruiz A, Sabri O, Sakhardande J, S?nchez-Juan P, Sando SB, Santana I, Sarazin M, Scheltens P, Schr?der J, Selnes P, Seo SW, Silva D, Skoog I, Snyder PJ, Soininen H, Sollberger M, Sperling RA, Spiru L, Stern Y, Stomrud E, Takeda A, Teichmann M, Teunissen CE, Thompson LI, Tomassen J, Tsolaki M, Vandenberghe R, Verbeek MM, Verhey FRJ, Villemagne V, Villeneuve S, Vogelgsang J, Waldemar G, Wallin A, Wallin ?K, Wiltfang J, Wolk DA, Yen TC, Zboch M, Zetterberg H. Prevalence Estimates of Amyloid Abnormality Across the Alzheimer Disease Clinical Spectrum. JAMA Neurol. 2022 03 01; 79(3):228-243.
Score: 0.114
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Perea JR, Bol?s M, Cuadros R, Garc?a E, Garc?a-Escudero V, Hern?ndez F, McManus RM, Heneka MT, Avila J. p38 Inhibition Decreases Tau Toxicity in Microglia and Improves Their Phagocytic Function. Mol Neurobiol. 2022 Mar; 59(3):1632-1648.
Score: 0.113
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Brosseron F, Maass A, Kleineidam L, Ravichandran KA, Gonz?lez PG, McManus RM, Ising C, Santarelli F, Kolbe CC, H?sler LM, Wolfsgruber S, Marqui? M, Boada M, Orellana A, de Rojas I, R?ske S, Peters O, Cosma NC, Cetindag A, Wang X, Priller J, Spruth EJ, Altenstein S, Schneider A, Fliessbach K, Wiltfang J, Schott BH, B?rger K, Janowitz D, Dichgans M, Perneczky R, Rauchmann BS, Teipel S, Kilimann I, Goerss D, Laske C, Munk MH, D?zel E, Yakupov R, Dobisch L, Metzger CD, Glanz W, Ewers M, Dechent P, Haynes JD, Scheffler K, Roy N, Rostamzadeh A, Teunissen CE, Marchant NL, Spottke A, Jucker M, Latz E, Wagner M, Mengel D, Synofzik M, Jessen F, Ramirez A, Ruiz A, Heneka MT. Soluble TAM receptors sAXL and sTyro3 predict structural and functional protection in Alzheimer's disease. Neuron. 2022 03 16; 110(6):1009-1022.e4.
Score: 0.113
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Wolfsgruber S, Kleineidam L, Weyrauch AS, Barkhoff M, R?ske S, Peters O, Preis L, Gref D, Spruth EJ, Altenstein S, Priller J, Flie?bach K, Schneider A, Wiltfang J, Bartels C, Jessen F, Maier F, D?zel E, Metzger C, Glanz W, Buerger K, Janowitz D, Perneczky R, Rauchmann BS, Kilimann I, Teipel S, Laske C, Munk MH, Roy N, Spottke A, Ramirez A, Heneka MT, Brosseron F, Wagner M. Relevance of Subjective Cognitive Decline in Older Adults with a First-Degree Family History of Alzheimer's Disease. J Alzheimers Dis. 2022; 87(2):545-555.
Score: 0.113
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Gordon MN, Heneka MT, Le Page LM, Limberger C, Morgan D, Tenner AJ, Terrando N, Willette AA, Willette SA. Impact of COVID-19 on the Onset and Progression of Alzheimer's Disease and Related Dementias: A Roadmap for Future Research. Alzheimers Dement. 2022 05; 18(5):1038-1046.
Score: 0.113
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Dyrba M, Hanzig M, Altenstein S, Bader S, Ballarini T, Brosseron F, Buerger K, Cantr? D, Dechent P, Dobisch L, D?zel E, Ewers M, Fliessbach K, Glanz W, Haynes JD, Heneka MT, Janowitz D, Keles DB, Kilimann I, Laske C, Maier F, Metzger CD, Munk MH, Perneczky R, Peters O, Preis L, Priller J, Rauchmann B, Roy N, Scheffler K, Schneider A, Schott BH, Spottke A, Spruth EJ, Weber MA, Ertl-Wagner B, Wagner M, Wiltfang J, Jessen F, Teipel SJ. Improving 3D convolutional neural network comprehensibility via interactive visualization of relevance maps: evaluation in Alzheimer's disease. Alzheimers Res Ther. 2021 11 23; 13(1):191.
Score: 0.112
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Joshi P, Riffel F, Kumar S, Villacampa N, Theil S, Parhizkar S, Haass C, Colonna M, Heneka MT, Arzberger T, Herms J, Walter J. TREM2 modulates differential deposition of modified and non-modified A? species in extracellular plaques and intraneuronal deposits. Acta Neuropathol Commun. 2021 10 18; 9(1):168.
Score: 0.112
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Islam MR, Kaurani L, Berulava T, Heilbronner U, Budde M, Centeno TP, Elerdashvili V, Zafieriou MP, Benito E, Sertel SM, Goldberg M, Senner F, Kalman JL, Burkhardt S, Oepen AS, Sakib MS, Kerimoglu C, Wirths O, Bickeb?ller H, Bartels C, Brosseron F, Buerger K, Cosma NC, Fliessbach K, Heneka MT, Janowitz D, Kilimann I, Kleinedam L, Laske C, Metzger CD, Munk MH, Perneczky R, Peters O, Priller J, Rauchmann BS, Roy N, Schneider A, Spottke A, Spruth EJ, Teipel S, Tscheuschler M, Wagner M, Wiltfang J, D?zel E, Jessen F, Rizzoli SO, Zimmermann WH, Schulze TG, Falkai P, Sananbenesi F, Fischer A. A microRNA signature that correlates with cognition and is a target against cognitive decline. EMBO Mol Med. 2021 11 08; 13(11):e13659.
Score: 0.111
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Rauchmann BS, Ersoezlue E, Stoecklein S, Keeser D, Brosseron F, Buerger K, Dechent P, Dobisch L, Ertl-Wagner B, Fliessbach K, Haynes JD, Heneka MT, Incesoy EI, Janowitz D, Kilimann I, Laske C, Metzger CD, Munk MH, Peters O, Priller J, Ramirez A, Roeske S, Roy N, Scheffler K, Schneider A, Spottke A, Spruth EJ, Teipel S, Tscheuschler M, Vukovich R, Wagner M, Wiltfang J, Yakupov R, Duezel E, Jessen F, Perneczky R. Resting-State Network Alterations Differ between Alzheimer's Disease Atrophy Subtypes. Cereb Cortex. 2021 10 01; 31(11):4901-4915.
Score: 0.111
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Joshi P, Riffel F, Satoh K, Enomoto M, Qamar S, Scheiblich H, Villacampa N, Kumar S, Theil S, Parhizkar S, Haass C, Heneka MT, Fraser PE, St George-Hyslop P, Walter J. Differential interaction with TREM2 modulates microglial uptake of modified A? species. Glia. 2021 12; 69(12):2917-2932.
Score: 0.110
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Bergstr?m S, Remnest?l J, Yousef J, Olofsson J, Markaki I, Carvalho S, Corvol JC, Kultima K, Kilander L, L?wenmark M, Ingelsson M, Blennow K, Zetterberg H, Nellg?rd B, Brosseron F, Heneka MT, Bosch B, Sanchez-Valle R, M?nberg A, Svenningsson P, Nilsson P. Multi-cohort profiling reveals elevated CSF levels of brain-enriched proteins in Alzheimer's disease. Ann Clin Transl Neurol. 2021 07; 8(7):1456-1470.
Score: 0.109
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de Rojas I, Moreno-Grau S, Tesi N, Grenier-Boley B, Andrade V, Jansen IE, Pedersen NL, Stringa N, Zettergren A, Hern?ndez I, Montrreal L, Ant?nez C, Antonell A, Tankard RM, Bis JC, Sims R, Bellenguez C, Quintela I, Gonz?lez-Perez A, Calero M, Franco-Mac?as E, Mac?as J, Blesa R, Cervera-Carles L, Men?ndez-Gonz?lez M, Frank-Garc?a A, Royo JL, Moreno F, Huerto Vilas R, Baquero M, Diez-Fairen M, Lage C, Garc?a-Madrona S, Garc?a-Gonz?lez P, Alarc?n-Mart?n E, Valero S, Sotolongo-Grau O, Ullgren A, Naj AC, Lemstra AW, Benaque A, P?rez-Cord?n A, Benussi A, R?bano A, Padovani A, Squassina A, de Mendon?a A, Arias Pastor A, Kok AAL, Meggy A, Pastor AB, Espinosa A, Corma-G?mez A, Mart?n Montes A, Sanabria ?, DeStefano AL, Schneider A, Haapasalo A, Kinhult St?hlbom A, Tybj?rg-Hansen A, Hartmann AM, Spottke A, Corbat?n-Anchuelo A, Rongve A, Borroni B, Arosio B, Nacmias B, Nordestgaard BG, Kunkle BW, Charbonnier C, Abdelnour C, Masullo C, Mart?nez Rodr?guez C, Mu?oz-Fernandez C, Dufouil C, Graff C, Ferreira CB, Chillotti C, Reynolds CA, Fenoglio C, Van Broeckhoven C, Clark C, Pisanu C, Satizabal CL, Holmes C, Buiza-Rueda D, Aarsland D, Rujescu D, Alcolea D, Galimberti D, Wallon D, Seripa D, Gr?nblatt E, Dardiotis E, D?zel E, Scarpini E, Conti E, Rubino E, Gelpi E, Rodriguez-Rodriguez E, Duron E, Boerwinkle E, Ferri E, Tagliavini F, K???kali F, Pasquier F, Sanchez-Garcia F, Mangialasche F, Jessen F, Nicolas G, Selb?k G, Ortega G, Ch?ne G, Hadjigeorgiou G, Rossi G, Spalletta G, Giaccone G, Grande G, Binetti G, Papenberg G, Hampel H, Bailly H, Zetterberg H, Soininen H, Karlsson IK, Alvarez I, Appollonio I, Giegling I, Skoog I, Saltvedt I, Rainero I, Rosas Allende I, Hort J, Diehl-Schmid J, Van Dongen J, Vidal JS, Lehtisalo J, Wiltfang J, Thomassen JQ, Kornhuber J, Haines JL, Vogelgsang J, Pineda JA, Fortea J, Popp J, Deckert J, Buerger K, Morgan K, Flie?bach K, Sleegers K, Molina-Porcel L, Kilander L, Weinhold L, Farrer LA, Wang LS, Kleineidam L, Farotti L, Parnetti L, Tremolizzo L, Hausner L, Benussi L, Froelich L, Ikram MA, Deniz-Naranjo MC, Tsolaki M, Rosende-Roca M, L?wenmark M, Hulsman M, Spallazzi M, Pericak-Vance MA, Esiri M, Bernal S?nchez-Arjona M, Dalmasso MC, Mart?nez-Larrad MT, Arcaro M, N?then MM, Fern?ndez-Fuertes M, Dichgans M, Ingelsson M, Herrmann MJ, Scherer M, Vyhnalek M, Kosmidis MH, Yannakoulia M, Schmid M, Ewers M, Heneka MT, Wagner M, Scamosci M, Kivipelto M, Hiltunen M, Zulaica M, Alegret M, Fornage M, Roberto N, van Schoor NM, Seidu NM, Banaj N, Armstrong NJ, Scarmeas N, Scherbaum N, Goldhardt O, Hanon O, Peters O, Skrobot OA, Quenez O, Lerch O, Boss? P, Caffarra P, Dionigi Rossi P, Sakka P, Mecocci P, Hoffmann P, Holmans PA, Fischer P, Riederer P, Yang Q, Marshall R, Kalaria RN, Mayeux R, Vandenberghe R, Cecchetti R, Ghidoni R, Frikke-Schmidt R, Sorbi S, H?gg S, Engelborghs S, Helisalmi S, Botne Sando S, Kern S, Archetti S, Boschi S, Fostinelli S, Gil S, Mendoza S, Mead S, Ciccone S, Djurovic S, Heilmann-Heimbach S, Riedel-Heller S, Kuulasmaa T, Del Ser T, Lebouvier T, Polak T, Ngandu T, Grimmer T, Bessi V, Escott-Price V, Giedraitis V, Deramecourt V, Maier W, Jian X, Pijnenburg YAL, Kehoe PG, Garcia-Ribas G, S?nchez-Juan P, Pastor P, P?rez-Tur J, Pi?ol-Ripoll G, Lopez de Munain A, Garc?a-Alberca JM, Bullido MJ, ?lvarez V, Lle? A, Real LM, Mir P, Medina M, Scheltens P, Holstege H, Marqui? M, S?ez ME, Carracedo ?, Amouyel P, Schellenberg GD, Williams J, Seshadri S, van Duijn CM, Mather KA, S?nchez-Valle R, Serrano-R?os M, Orellana A, T?rraga L, Blennow K, Huisman M, Andreassen OA, Posthuma D, Clarim?n J, Boada M, van der Flier WM, Ramirez A, Lambert JC, van der Lee SJ, Ruiz A. Common variants in Alzheimer's disease and risk stratification by polygenic risk scores. Nat Commun. 2021 06 07; 12(1):3417.
Score: 0.109
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Herdick M, Dyrba M, Fritz HJ, Altenstein S, Ballarini T, Brosseron F, Buerger K, Can Cetindag A, Dechent P, Dobisch L, Duezel E, Ertl-Wagner B, Fliessbach K, Dawn Freiesleben S, Frommann I, Glanz W, Dylan Haynes J, Heneka MT, Janowitz D, Kilimann I, Laske C, Metzger CD, Munk MH, Peters O, Priller J, Roy N, Scheffler K, Schneider A, Spottke A, Jakob Spruth E, Tscheuschler M, Vukovich R, Wiltfang J, Jessen F, Teipel S, Grothe MJ. Multimodal MRI analysis of basal forebrain structure and function across the Alzheimer's disease spectrum. Neuroimage Clin. 2020; 28:102495.
Score: 0.105
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Sannemann L, Schild AK, Altenstein S, Bartels C, Brosseron F, Buerger K, Cosma NC, Fliessbach K, Freiesleben SD, Glanz W, Heneka MT, Janowitz D, Kilimann I, Kobeleva X, Laske C, Metzger CD, Munk MHJ, Perneczky R, Peters O, Polcher A, Priller J, Rauchmann B, R?sch C, Rudolph J, Schneider A, Spottke A, Spruth EJ, Teipel S, Vukovich R, Wagner M, Wiltfang J, Wolfsgruber S, Duezel E, Jessen F. Neuropsychiatric symptoms in at-risk groups for AD dementia and their association with worry and AD biomarkers-results from the DELCODE study. Alzheimers Res Ther. 2020 10 16; 12(1):131.
Score: 0.104
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Finsterwalder S, Vlegels N, Gesierich B, Araque Caballero M?, Weaver NA, Franzmeier N, Georgakis MK, Konieczny MJ, Koek HL, Karch CM, Graff-Radford NR, Salloway S, Oh H, Allegri RF, Chhatwal JP, Jessen F, D?zel E, Dobisch L, Metzger C, Peters O, Incesoy EI, Priller J, Spruth EJ, Schneider A, Flie?bach K, Buerger K, Janowitz D, Teipel SJ, Kilimann I, Laske C, Buchmann M, Heneka MT, Brosseron F, Spottke A, Roy N, Ertl-Wagner B, Scheffler K, Seo SW, Kim Y, Na DL, Kim HJ, Jang H, Ewers M, Levin J, Schmidt R, Pasternak O, Dichgans M, Biessels GJ, Duering M. Small vessel disease more than Alzheimer's disease determines diffusion MRI alterations in memory clinic patients. Alzheimers Dement. 2020 11; 16(11):1504-1514.
Score: 0.103
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Schr?der N, Schaffrath A, Welter JA, Putzka T, Griep A, Ziegler P, Brandt E, Samer S, Heneka MT, Kaddatz H, Zhan J, Kipp E, Pufe T, Tauber SC, Kipp M, Brandenburg LO. Inhibition of formyl peptide receptors improves the outcome in a mouse model of Alzheimer disease. J Neuroinflammation. 2020 Apr 24; 17(1):131.
Score: 0.101
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Kleineidam L, Chouraki V, Pr?chnicki T, van der Lee SJ, Madrid-M?rquez L, Wagner-Thelen H, Karaca I, Weinhold L, Wolfsgruber S, Boland A, Martino Adami PV, Lewczuk P, Popp J, Brosseron F, Jansen IE, Hulsman M, Kornhuber J, Peters O, Berr C, Heun R, Fr?lich L, Tzourio C, Dartigues JF, H?ll M, Espinosa A, Hern?ndez I, de Rojas I, Orellana A, Valero S, Stringa N, van Schoor NM, Huisman M, Scheltens P, R?ther E, Deleuze JF, Wiltfang J, Tarraga L, Schmid M, Scherer M, Riedel-Heller S, Heneka MT, Amouyel P, Jessen F, Boada M, Maier W, Schneider A, Gonz?lez-P?rez A, van der Flier WM, Wagner M, Lambert JC, Holstege H, S?ez ME, Latz E, Ruiz A, Ramirez A. PLCG2 protective variant p.P522R modulates tau pathology and disease progression in patients with mild cognitive impairment. Acta Neuropathol. 2020 06; 139(6):1025-1044.
Score: 0.100
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Itzhaki RF, Golde TE, Heneka MT, Readhead B. Do infections have a role in the pathogenesis of Alzheimer disease? Nat Rev Neurol. 2020 04; 16(4):193-197.
Score: 0.100
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Brosseron F, Kolbe CC, Santarelli F, Carvalho S, Antonell A, Castro-Gomez S, Tacik P, Namasivayam AA, Mangone G, Schneider R, Latz E, W?llner U, Svenningsson P, S?nchez-Valle R, Molinuevo JL, Corvol JC, Heneka MT. Multicenter Alzheimer's and Parkinson's disease immune biomarker verification study. Alzheimers Dement. 2020 02; 16(2):292-304.
Score: 0.099
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Mantile F, Capasso A, Villacampa N, Donnini M, Liguori GL, Constantin G, De Berardinis P, Heneka MT, Prisco A. Vaccination with (1-11)E2 in alum efficiently induces an antibody response to ?-amyloid without affecting brain ?-amyloid load and microglia activation in 3xTg mice. Aging Clin Exp Res. 2021 May; 33(5):1383-1387.
Score: 0.098
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Webers A, Heneka MT, Gleeson PA. The role of innate immune responses and neuroinflammation in amyloid accumulation and progression of Alzheimer's disease. Immunol Cell Biol. 2020 01; 98(1):28-41.
Score: 0.098
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Bertens D, Vos S, Kehoe P, Wolf H, Nobili F, Mendon?a A, van Rossum I, Hort J, Molinuevo JL, Heneka M, Petersen R, Scheltens P, Visser PJ. Use of mild cognitive impairment and prodromal AD/MCI due to AD in clinical care: a European survey. Alzheimers Res Ther. 2019 08 22; 11(1):74.
Score: 0.096
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Miebach L, Wolfsgruber S, Polcher A, Peters O, Menne F, Luther K, Incesoy E, Priller J, Spruth E, Altenstein S, Buerger K, Catak C, Janowitz D, Perneczky R, Utecht J, Laske C, Buchmann M, Schneider A, Fliessbach K, Kalbhen P, Heneka MT, Brosseron F, Spottke A, Roy N, Teipel SJ, Kilimann I, Wiltfang J, Bartels C, D?zel E, Dobisch L, Metzger C, Meiberth D, Ramirez A, Jessen F, Wagner M. Which features of subjective cognitive decline are related to amyloid pathology? Findings from the DELCODE study. Alzheimers Res Ther. 2019 07 31; 11(1):66.
Score: 0.096
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Esteve P, Rueda-Carrasco J, In?s Mateo M, Martin-Bermejo MJ, Draffin J, Pereyra G, Sandon?s ?, Crespo I, Moreno I, Aso E, Garcia-Esparcia P, Gomez-Tortosa E, R?bano A, Fortea J, Alcolea D, Lleo A, Heneka MT, Valpuesta JM, Esteban JA, Ferrer I, Dom?nguez M, Bovolenta P. Elevated levels of Secreted-Frizzled-Related-Protein 1 contribute to Alzheimer's disease pathogenesis. Nat Neurosci. 2019 08; 22(8):1258-1268.
Score: 0.095
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Franzmeier N, Ren J, Damm A, Mont?-Rubio G, Boada M, Ruiz A, Ramirez A, Jessen F, D?zel E, Rodr?guez G?mez O, Benzinger T, Goate A, Karch CM, Fagan AM, McDade E, Buerger K, Levin J, Duering M, Dichgans M, Su?rez-Calvet M, Haass C, Gordon BA, Lim YY, Masters CL, Janowitz D, Catak C, Wolfsgruber S, Wagner M, Milz E, Moreno-Grau S, Teipel S, Grothe MJ, Kilimann I, Rossor M, Fox N, Laske C, Chhatwal J, Falkai P, Perneczky R, Lee JH, Spottke A, Boecker H, Brosseron F, Fliessbach K, Heneka MT, Nestor P, Peters O, Fuentes M, Menne F, Priller J, Spruth EJ, Franke C, Schneider A, Westerteicher C, Speck O, Wiltfang J, Bartels C, Araque Caballero M?, Metzger C, Bittner D, Salloway S, Danek A, Hassenstab J, Yakushev I, Schofield PR, Morris JC, Bateman RJ, Ewers M. The BDNFVal66Met SNP modulates the association between beta-amyloid and hippocampal disconnection in Alzheimer's disease. Mol Psychiatry. 2021 02; 26(2):614-628.
Score: 0.093
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Wolfsgruber S, Molinuevo JL, Wagner M, Teunissen CE, Rami L, Coll-Padr?s N, Bouwman FH, Slot RER, Wesselman LMP, Peters O, Luther K, Buerger K, Priller J, Laske C, Teipel S, Spottke A, Heneka MT, D?zel E, Drzezga A, Wiltfang J, Sikkes SAM, van der Flier WM, Jessen F. Prevalence of abnormal Alzheimer's disease biomarkers in patients with subjective cognitive decline: cross-sectional comparison of three European memory clinic samples. Alzheimers Res Ther. 2019 01 17; 11(1):8.
Score: 0.092
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Teipel SJ, Kuper-Smith JO, Bartels C, Brosseron F, Buchmann M, Buerger K, Catak C, Janowitz D, Dechent P, Dobisch L, Ertl-Wagner B, Flie?bach K, Haynes JD, Heneka MT, Kilimann I, Laske C, Li S, Menne F, Metzger CD, Priller J, Pross V, Ramirez A, Scheffler K, Schneider A, Spottke A, Spruth EJ, Wagner M, Wiltfang J, Wolfsgruber S, D?zel E, Jessen F, Dyrba M. Multicenter Tract-Based Analysis of Microstructural Lesions within the Alzheimer's Disease Spectrum: Association with Amyloid Pathology and Diagnostic Usefulness. J Alzheimers Dis. 2019; 72(2):455-465.
Score: 0.092
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Hu X, Teunissen CE, Spottke A, Heneka MT, D?zel E, Peters O, Li S, Priller J, Buerger K, Teipel S, Laske C, Verfaillie SCJ, Barkhof F, Coll-Padr?s N, Rami L, Molinuevo JL, van der Flier WM, Jessen F. Smaller medial temporal lobe volumes in individuals with subjective cognitive decline and biomarker evidence of Alzheimer's disease-Data from three memory clinic studies. Alzheimers Dement. 2019 02; 15(2):185-193.
Score: 0.091
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Tzeng TC, Hasegawa Y, Iguchi R, Cheung A, Caffrey DR, Thatcher EJ, Mao W, Germain G, Tamburro ND, Okabe S, Heneka MT, Latz E, Futai K, Golenbock DT. Inflammasome-derived cytokine IL18 suppresses amyloid-induced seizures in Alzheimer-prone mice. Proc Natl Acad Sci U S A. 2018 09 04; 115(36):9002-9007.
Score: 0.090
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Unger MS, Marschallinger J, Kaindl J, Klein B, Johnson M, Khundakar AA, Ro?ner S, Heneka MT, Couillard-Despres S, Rockenstein E, Masliah E, Attems J, Aigner L. Doublecortin expression in CD8+ T-cells and microglia at sites of amyloid-? plaques: A potential role in shaping plaque pathology? Alzheimers Dement. 2018 08; 14(8):1022-1037.
Score: 0.087
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Franzmeier N, D?zel E, Jessen F, Buerger K, Levin J, Duering M, Dichgans M, Haass C, Su?rez-Calvet M, Fagan AM, Paumier K, Benzinger T, Masters CL, Morris JC, Perneczky R, Janowitz D, Catak C, Wolfsgruber S, Wagner M, Teipel S, Kilimann I, Ramirez A, Rossor M, Jucker M, Chhatwal J, Spottke A, Boecker H, Brosseron F, Falkai P, Fliessbach K, Heneka MT, Laske C, Nestor P, Peters O, Fuentes M, Menne F, Priller J, Spruth EJ, Franke C, Schneider A, Kofler B, Westerteicher C, Speck O, Wiltfang J, Bartels C, Araque Caballero M?, Metzger C, Bittner D, Weiner M, Lee JH, Salloway S, Danek A, Goate A, Schofield PR, Bateman RJ, Ewers M. Left frontal hub connectivity delays cognitive impairment in autosomal-dominant and sporadic Alzheimer's disease. Brain. 2018 04 01; 141(4):1186-1200.
Score: 0.087
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Enkirch SJ, Trasch?tz A, M?ller A, Widmann CN, Gielen GH, Heneka MT, Jurcoane A, Schild HH, Hattingen E. The ERICA Score: An MR Imaging-based Visual Scoring System for the Assessment of Entorhinal Cortex Atrophy in Alzheimer Disease. Radiology. 2018 Jul; 288(1):226-333.
Score: 0.087
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Jessen F, Spottke A, Boecker H, Brosseron F, Buerger K, Catak C, Fliessbach K, Franke C, Fuentes M, Heneka MT, Janowitz D, Kilimann I, Laske C, Menne F, Nestor P, Peters O, Priller J, Pross V, Ramirez A, Schneider A, Speck O, Spruth EJ, Teipel S, Vukovich R, Westerteicher C, Wiltfang J, Wolfsgruber S, Wagner M, D?zel E. Design and first baseline data of the DZNE multicenter observational study on predementia Alzheimer's disease (DELCODE). Alzheimers Res Ther. 2018 02 07; 10(1):15.
Score: 0.086
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Teipel SJ, Metzger CD, Brosseron F, Buerger K, Brueggen K, Catak C, Diesing D, Dobisch L, Fliebach K, Franke C, Heneka MT, Kilimann I, Kofler B, Menne F, Peters O, Polcher A, Priller J, Schneider A, Spottke A, Spruth EJ, Thelen M, Thyrian RJ, Wagner M, D?zel E, Jessen F, Dyrba M. Multicenter Resting State Functional Connectivity in Prodromal and Dementia Stages of Alzheimer's Disease. J Alzheimers Dis. 2018; 64(3):801-813.
Score: 0.086
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Ardura-Fabregat A, Boddeke EWGM, Boza-Serrano A, Brioschi S, Castro-Gomez S, Ceyz?riat K, Dansokho C, Dierkes T, Gelders G, Heneka MT, Hoeijmakers L, Hoffmann A, Iaccarino L, Jahnert S, Kuhbandner K, Landreth G, Lonnemann N, L?schmann PA, McManus RM, Paulus A, Reemst K, Sanchez-Caro JM, Tiberi A, Van der Perren A, Vautheny A, Venegas C, Webers A, Weydt P, Wijasa TS, Xiang X, Yang Y. Targeting Neuroinflammation to Treat Alzheimer's Disease. CNS Drugs. 2017 12; 31(12):1057-1082.
Score: 0.085
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Unger MS, Marschallinger J, Kaindl J, H?fling C, Rossner S, Heneka MT, Van der Linden A, Aigner L. Early Changes in Hippocampal Neurogenesis in Transgenic Mouse Models for Alzheimer's Disease. Mol Neurobiol. 2016 10; 53(8):5796-806.
Score: 0.078
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Heneka MT, Nicotera P. Thoughts on Obesity and Brain Glucose. Cell. 2016 May 05; 165(4):773-5.
Score: 0.076
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Su?rez-Calvet M, Kleinberger G, Araque Caballero M?, Brendel M, Rominger A, Alcolea D, Fortea J, Lle? A, Blesa R, Gispert JD, S?nchez-Valle R, Antonell A, Rami L, Molinuevo JL, Brosseron F, Trasch?tz A, Heneka MT, Struyfs H, Engelborghs S, Sleegers K, Van Broeckhoven C, Zetterberg H, Nellg?rd B, Blennow K, Crispin A, Ewers M, Haass C. sTREM2 cerebrospinal fluid levels are a potential biomarker for microglia activity in early-stage Alzheimer's disease and associate with neuronal injury markers. EMBO Mol Med. 2016 05; 8(5):466-76.
Score: 0.076
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Bach JP, Gold M, Mengel D, Hattesohl A, Lubbe D, Schmid S, Tackenberg B, Rieke J, Maddula S, Baumbach JI, Nell C, Boeselt T, Michelis J, Alferink J, Heneka M, Oertel W, Jessen F, Janciauskiene S, Vogelmeier C, Dodel R, Koczulla AR. Measuring Compounds in Exhaled Air to Detect Alzheimer's Disease and Parkinson's Disease. PLoS One. 2015; 10(7):e0132227.
Score: 0.072
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Heilmann S, Drichel D, Clarimon J, Fern?ndez V, Lacour A, Wagner H, Thelen M, Hern?ndez I, Fortea J, Alegret M, Blesa R, Maule?n A, Roca MR, Kornhuber J, Peters O, Heun R, Fr?lich L, H?ll M, Heneka MT, R?ther E, Riedel-Heller S, Scherer M, Wiltfang J, Jessen F, Becker T, T?rraga L, Boada M, Maier W, Lle? A, Ruiz A, N?then MM, Ramirez A. PLD3 in non-familial Alzheimer's disease. Nature. 2015 Apr 02; 520(7545):E3-5.
Score: 0.071
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Krauthausen M, Kummer MP, Zimmermann J, Reyes-Irisarri E, Terwel D, Bulic B, Heneka MT, M?ller M. CXCR3 promotes plaque formation and behavioral deficits in an Alzheimer's disease model. J Clin Invest. 2015 Jan; 125(1):365-78.
Score: 0.069
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Ramirez A, van der Flier WM, Herold C, Ramonet D, Heilmann S, Lewczuk P, Popp J, Lacour A, Drichel D, Louwersheimer E, Kummer MP, Cruchaga C, Hoffmann P, Teunissen C, Holstege H, Kornhuber J, Peters O, Naj AC, Chouraki V, Bellenguez C, Gerrish A, Heun R, Fr?lich L, H?ll M, Buscemi L, Herms S, K?lsch H, Scheltens P, Breteler MM, R?ther E, Wiltfang J, Goate A, Jessen F, Maier W, Heneka MT, Becker T, N?then MM. SUCLG2 identified as both a determinator of CSF A?1-42 levels and an attenuator of cognitive decline in Alzheimer's disease. Hum Mol Genet. 2014 Dec 15; 23(24):6644-58.
Score: 0.067
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Malhotra A, Younesi E, G?ndel M, M?ller B, Heneka MT, Hofmann-Apitius M. ADO: a disease ontology representing the domain knowledge specific to Alzheimer's disease. Alzheimers Dement. 2014 Mar; 10(2):238-46.
Score: 0.063
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Molinuevo JL, Gispert JD, Dubois B, Heneka MT, Lleo A, Engelborghs S, Pujol J, de Souza LC, Alcolea D, Jessen F, Sarazin M, Lamari F, Balasa M, Antonell A, Rami L. The AD-CSF-index discriminates Alzheimer's disease patients from healthy controls: a validation study. J Alzheimers Dis. 2013; 36(1):67-77.
Score: 0.061
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Kummer MP, Vogl T, Axt D, Griep A, Vieira-Saecker A, Jessen F, Gelpi E, Roth J, Heneka MT. Mrp14 deficiency ameliorates amyloid ? burden by increasing microglial phagocytosis and modulation of amyloid precursor protein processing. J Neurosci. 2012 Dec 05; 32(49):17824-9.
Score: 0.060
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Rapic S, Backes H, Viel T, Kummer MP, Monfared P, Neumaier B, Vollmar S, Hoehn M, Van der Linden A, Heneka MT, Jacobs AH. Imaging microglial activation and glucose consumption in a mouse model of Alzheimer's disease. Neurobiol Aging. 2013 Jan; 34(1):351-4.
Score: 0.058
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Parpura V, Heneka MT, Montana V, Oliet SH, Schousboe A, Haydon PG, Stout RF, Spray DC, Reichenbach A, Pannicke T, Pekny M, Pekna M, Zorec R, Verkhratsky A. Glial cells in (patho)physiology. J Neurochem. 2012 Apr; 121(1):4-27.
Score: 0.057
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Kummer MP, Hermes M, Delekarte A, Hammerschmidt T, Kumar S, Terwel D, Walter J, Pape HC, K?nig S, Roeber S, Jessen F, Klockgether T, Korte M, Heneka MT. Nitration of tyrosine 10 critically enhances amyloid ? aggregation and plaque formation. Neuron. 2011 Sep 08; 71(5):833-44.
Score: 0.055
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Mildner A, Schlevogt B, Kierdorf K, B?ttcher C, Erny D, Kummer MP, Quinn M, Br?ck W, Bechmann I, Heneka MT, Priller J, Prinz M. Distinct and non-redundant roles of microglia and myeloid subsets in mouse models of Alzheimer's disease. J Neurosci. 2011 Aug 03; 31(31):11159-71.
Score: 0.055
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Mattsson N, Andreasson U, Persson S, Arai H, Batish SD, Bernardini S, Bocchio-Chiavetto L, Blankenstein MA, Carrillo MC, Chalbot S, Coart E, Chiasserini D, Cutler N, Dahlfors G, Duller S, Fagan AM, Forlenza O, Frisoni GB, Galasko D, Galimberti D, Hampel H, Handberg A, Heneka MT, Herskovits AZ, Herukka SK, Holtzman DM, Humpel C, Hyman BT, Iqbal K, Jucker M, Kaeser SA, Kaiser E, Kapaki E, Kidd D, Klivenyi P, Knudsen CS, Kummer MP, Lui J, Llad? A, Lewczuk P, Li QX, Martins R, Masters C, McAuliffe J, Mercken M, Moghekar A, Molinuevo JL, Montine TJ, Nowatzke W, O'Brien R, Otto M, Paraskevas GP, Parnetti L, Petersen RC, Prvulovic D, de Reus HP, Rissman RA, Scarpini E, Stefani A, Soininen H, Schr?der J, Shaw LM, Skinningsrud A, Skrogstad B, Spreer A, Talib L, Teunissen C, Trojanowski JQ, Tumani H, Umek RM, Van Broeck B, Vanderstichele H, Vecsei L, Verbeek MM, Windisch M, Zhang J, Zetterberg H, Blennow K. The Alzheimer's Association external quality control program for cerebrospinal fluid biomarkers. Alzheimers Dement. 2011 Jul; 7(4):386-395.e6.
Score: 0.055
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Kumar S, Rezaei-Ghaleh N, Terwel D, Thal DR, Richard M, Hoch M, Mc Donald JM, W?llner U, Glebov K, Heneka MT, Walsh DM, Zweckstetter M, Walter J. Extracellular phosphorylation of the amyloid ?-peptide promotes formation of toxic aggregates during the pathogenesis of Alzheimer's disease. EMBO J. 2011 Jun 01; 30(11):2255-65.
Score: 0.054
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Perez Nievas BG, Hammerschmidt T, Kummer MP, Terwel D, Leza JC, Heneka MT. Restraint stress increases neuroinflammation independently of amyloid ? levels in amyloid precursor protein/PS1 transgenic mice. J Neurochem. 2011 Jan; 116(1):43-52.
Score: 0.052
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Heneka MT, Rodr?guez JJ, Verkhratsky A. Neuroglia in neurodegeneration. Brain Res Rev. 2010 May; 63(1-2):189-211.
Score: 0.049
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Jiang Q, Heneka M, Landreth GE. The role of peroxisome proliferator-activated receptor-gamma (PPARgamma) in Alzheimer's disease: therapeutic implications. CNS Drugs. 2008; 22(1):1-14.
Score: 0.043
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Kalinin S, Gavrilyuk V, Polak PE, Vasser R, Zhao J, Heneka MT, Feinstein DL. Noradrenaline deficiency in brain increases beta-amyloid plaque burden in an animal model of Alzheimer's disease. Neurobiol Aging. 2007 Aug; 28(8):1206-14.
Score: 0.039
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Sastre M, Dewachter I, Rossner S, Bogdanovic N, Rosen E, Borghgraef P, Evert BO, Dumitrescu-Ozimek L, Thal DR, Landreth G, Walter J, Klockgether T, van Leuven F, Heneka MT. Nonsteroidal anti-inflammatory drugs repress beta-secretase gene promoter activity by the activation of PPARgamma. Proc Natl Acad Sci U S A. 2006 Jan 10; 103(2):443-8.
Score: 0.037
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Klotz L, Sastre M, Kreutz A, Gavrilyuk V, Klockgether T, Feinstein DL, Heneka MT. Noradrenaline induces expression of peroxisome proliferator activated receptor gamma (PPARgamma) in murine primary astrocytes and neurons. J Neurochem. 2003 Aug; 86(4):907-16.
Score: 0.032
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Labzin LI, Heneka MT, Latz E. Innate Immunity and Neurodegeneration. Annu Rev Med. 2018 01 29; 69:437-449.
Score: 0.021
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M?ller S, Preische O, G?pfert JC, Ya?ez VAC, Joos TO, Boecker H, D?zel E, Falkai P, Priller J, Buerger K, Catak C, Janowitz D, Heneka MT, Brosseron F, Nestor P, Peters O, Menne F, Schipke CG, Schneider A, Spottke A, Flie?bach K, Kilimann I, Teipel S, Wagner M, Wiltfang J, Jessen F, Laske C. Tau plasma levels in subjective cognitive decline: Results from the DELCODE study. Sci Rep. 2017 08 25; 7(1):9529.
Score: 0.021
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Willem M, Tahirovic S, Busche MA, Ovsepian SV, Chafai M, Kootar S, Hornburg D, Evans LD, Moore S, Daria A, Hampel H, M?ller V, Giudici C, Nuscher B, Wenninger-Weinzierl A, Kremmer E, Heneka MT, Thal DR, Giedraitis V, Lannfelt L, M?ller U, Livesey FJ, Meissner F, Herms J, Konnerth A, Marie H, Haass C. ?-Secretase processing of APP inhibits neuronal activity in the hippocampus. Nature. 2015 Oct 15; 526(7573):443-7.
Score: 0.018
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Kleinberger G, Yamanishi Y, Su?rez-Calvet M, Czirr E, Lohmann E, Cuyvers E, Struyfs H, Pettkus N, Wenninger-Weinzierl A, Mazaheri F, Tahirovic S, Lle? A, Alcolea D, Fortea J, Willem M, Lammich S, Molinuevo JL, S?nchez-Valle R, Antonell A, Ramirez A, Heneka MT, Sleegers K, van der Zee J, Martin JJ, Engelborghs S, Demirtas-Tatlidede A, Zetterberg H, Van Broeckhoven C, Gurvit H, Wyss-Coray T, Hardy J, Colonna M, Haass C. TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis. Sci Transl Med. 2014 Jul 02; 6(243):243ra86.
Score: 0.017
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Thelen M, Razquin C, Hern?ndez I, Gorostidi A, S?nchez-Valle R, Ortega-Cubero S, Wolfsgruber S, Drichel D, Fliessbach K, Duenkel T, Damian M, Heilmann S, Slotosch A, Lennarz M, Seijo-Mart?nez M, Rene R, Kornhuber J, Peters O, Luckhaus C, Jahn H, H?ll M, R?ther E, Wiltfang J, Lorenzo E, Gascon J, Lle? A, Llad? A, Campdelacreu J, Moreno F, Ahmadzadehfar H, Fortea J, Indakoetxea B, Heneka MT, Wetter A, Pastor MA, Riverol M, Becker T, Fr?lich L, T?rraga L, Boada M, Wagner M, Jessen F, Maier W, Clarim?n J, L?pez de Munain A, Ruiz A, Pastor P, Ramirez A. Investigation of the role of rare TREM2 variants in frontotemporal dementia subtypes. Neurobiol Aging. 2014 Nov; 35(11):2657.e13-2657.e19.
Score: 0.017
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van der Zee J, Gijselinck I, Dillen L, Van Langenhove T, Theuns J, Engelborghs S, Philtjens S, Vandenbulcke M, Sleegers K, Sieben A, B?umer V, Maes G, Corsmit E, Borroni B, Padovani A, Archetti S, Perneczky R, Diehl-Schmid J, de Mendon?a A, Miltenberger-Miltenyi G, Pereira S, Pimentel J, Nacmias B, Bagnoli S, Sorbi S, Graff C, Chiang HH, Westerlund M, Sanchez-Valle R, Llado A, Gelpi E, Santana I, Almeida MR, Santiago B, Frisoni G, Zanetti O, Bonvicini C, Synofzik M, Maetzler W, Vom Hagen JM, Sch?ls L, Heneka MT, Jessen F, Matej R, Parobkova E, Kovacs GG, Str?bel T, Sarafov S, Tournev I, Jordanova A, Danek A, Arzberger T, Fabrizi GM, Testi S, Salmon E, Santens P, Martin JJ, Cras P, Vandenberghe R, De Deyn PP, Cruts M, Van Broeckhoven C, van der Zee J, Gijselinck I, Dillen L, Van Langenhove T, Theuns J, Philtjens S, Sleegers K, B?umer V, Maes G, Corsmit E, Cruts M, Van Broeckhoven C, van der Zee J, Gijselinck I, Dillen L, Van Langenhove T, Philtjens S, Theuns J, Sleegers K, B?umer V, Maes G, Cruts M, Van Broeckhoven C, Engelborghs S, De Deyn PP, Cras P, Engelborghs S, De Deyn PP, Vandenbulcke M, Vandenbulcke M, Borroni B, Padovani A, Archetti S, Perneczky R, Diehl-Schmid J, Synofzik M, Maetzler W, M?ller Vom Hagen J, Sch?ls L, Synofzik M, Maetzler W, M?ller Vom Hagen J, Sch?ls L, Heneka MT, Jessen F, Ramirez A, Kurzwelly D, Sachtleben C, Mairer W, de Mendon?a A, Miltenberger-Miltenyi G, Pereira S, Firmo C, Pimentel J, Sanchez-Valle R, Llado A, Antonell A, Molinuevo J, Gelpi E, Graff C, Chiang HH, Westerlund M, Graff C, Kinhult St?hlbom A, Thonberg H, Nennesmo I, B?rjesson-Hanson A, Nacmias B, Bagnoli S, Sorbi S, Bessi V, Piaceri I, Santana I, Santiago B, Santana I, Helena Ribeiro M, Ros?rio Almeida M, Oliveira C, Massano J, Garret C, Pires P, Frisoni G, Zanetti O, Bonvicini C, Sarafov S, Tournev I, Jordanova A, Tournev I, Kovacs GG, Str?bel T, Heneka MT, Jessen F, Ramirez A, Kurzwelly D, Sachtleben C, Mairer W, Jessen F, Matej R, Parobkova E, Danel A, Arzberger T, Maria Fabrizi G, Testi S, Ferrari S, Cavallaro T, Salmon E, Santens P, Cras P. A pan-European study of the C9orf72 repeat associated with FTLD: geographic prevalence, genomic instability, and intermediate repeats. Hum Mutat. 2013 Feb; 34(2):363-73.
Score: 0.015
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Liu S, Liu Y, Hao W, Wolf L, Kiliaan AJ, Penke B, R?be CE, Walter J, Heneka MT, Hartmann T, Menger MD, Fassbender K. TLR2 is a primary receptor for Alzheimer's amyloid ? peptide to trigger neuroinflammatory activation. J Immunol. 2012 Feb 01; 188(3):1098-107.
Score: 0.014
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Tamboli IY, Barth E, Christian L, Siepmann M, Kumar S, Singh S, Tolksdorf K, Heneka MT, L?tjohann D, Wunderlich P, Walter J. Statins promote the degradation of extracellular amyloid {beta}-peptide by microglia via stimulation of exosome-associated insulin-degrading enzyme (IDE) secretion. J Biol Chem. 2010 Nov 26; 285(48):37405-14.
Score: 0.013
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Tamboli IY, Prager K, Barth E, Heneka M, Sandhoff K, Walter J. Inhibition of glycosphingolipid biosynthesis reduces secretion of the beta-amyloid precursor protein and amyloid beta-peptide. J Biol Chem. 2005 Jul 29; 280(30):28110-7.
Score: 0.009