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Michael Heneka to Alzheimer Disease

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This is a "connection" page, showing publications Michael Heneka has written about Alzheimer Disease.
Michael Heneka
Connection Strength
27.081
Alzheimer Disease
  1. Villacampa N, Sarlus H, Martorell P, Bhalla K, Castro-Gomez S, Vieira-Saecker A, Slutzkin I, H?ndler K, Venegas C, McManus R, Ulas T, Beyer M, Segal E, Heneka MT. Proliferating Microglia Exhibit Unique Transcriptional and Functional Alterations in Alzheimer's Disease. ASN Neuro. 2025; 17(1):2506406.
    View in: PubMed
    Score: 0.597
  2. Heneka MT, Gauthier S, Chandekar SA, Hviid Hahn-Pedersen J, Bentsen MA, Zetterberg H. Neuroinflammatory fluid biomarkers in patients with Alzheimer's disease: a systematic literature review. Mol Psychiatry. 2025 Jun; 30(6):2783-2798.
    View in: PubMed
    Score: 0.589
  3. McManus RM, Komes MP, Griep A, Santarelli F, Schwartz S, Ram?n Perea J, Schlachetzki JCM, Bouvier DS, Khalil MA, Lauterbach MA, Heinemann L, Schl?ter T, Pour MS, Lovotti M, Stahl R, Duthie F, Rodr?guez-Alc?zar JF, Schmidt SV, Spitzer J, Noori P, Maillo A, Boettcher A, Herron B, McConville J, Gomez-Cabrero D, Tegn?r J, Glass CK, Hiller K, Latz E, Heneka MT. NLRP3-mediated glutaminolysis controls microglial phagocytosis to promote Alzheimer's disease progression. Immunity. 2025 Feb 11; 58(2):326-343.e11.
    View in: PubMed
    Score: 0.585
  4. Heneka MT, van der Flier WM, Jessen F, Hoozemanns J, Thal DR, Boche D, Brosseron F, Teunissen C, Zetterberg H, Jacobs AH, Edison P, Ramirez A, Cruchaga C, Lambert JC, Laza AR, Sanchez-Mut JV, Fischer A, Castro-Gomez S, Stein TD, Kleineidam L, Wagner M, Neher JJ, Cunningham C, Singhrao SK, Prinz M, Glass CK, Schlachetzki JCM, Butovsky O, Kleemann K, De Jaeger PL, Scheiblich H, Brown GC, Landreth G, Moutinho M, Grutzendler J, Gomez-Nicola D, McManus RM, Andreasson K, Ising C, Karabag D, Baker DJ, Liddelow SA, Verkhratsky A, Tansey M, Monsonego A, Aigner L, Doroth?e G, Nave KA, Simons M, Constantin G, Rosenzweig N, Pascual A, Petzold GC, Kipnis J, Venegas C, Colonna M, Walter J, Tenner AJ, O'Banion MK, Steinert JR, Feinstein DL, Sastre M, Bhaskar K, Hong S, Schafer DP, Golde T, Ransohoff RM, Morgan D, Breitner J, Mancuso R, Riechers SP. Neuroinflammation in Alzheimer disease. Nat Rev Immunol. 2025 May; 25(5):321-352.
    View in: PubMed
    Score: 0.579
  5. Heneka MT, Morgan D, Jessen F. Passive anti-amyloid ? immunotherapy in Alzheimer's disease-opportunities and challenges. Lancet. 2024 11 30; 404(10468):2198-2208.
    View in: PubMed
    Score: 0.576
  6. Botella Lucena P, Heneka MT. Inflammatory aspects of Alzheimer's disease. Acta Neuropathol. 2024 Aug 28; 148(1):31.
    View in: PubMed
    Score: 0.568
  7. Mary A, Mancuso R, Heneka MT. Immune Activation in Alzheimer Disease. Annu Rev Immunol. 2024 Jun; 42(1):585-613.
    View in: PubMed
    Score: 0.560
  8. Heneka MT. TREM1 is the new kid on the block for the aging-associated innate immune response and Alzheimer's disease. Nat Immunol. 2024 Jun; 25(6):938-940.
    View in: PubMed
    Score: 0.558
  9. Heneka M, Gauthier S, Chandekar SA, Hahn-Pedersen JH, Bentsen M, Zetterberg H. The Role of Neuroinflammation in Alzheimer's Disease: A Systematic Literature Review (P7-9.013). Neurology. 2024 Apr 09; 102(7_supplement_1):3344.
    View in: PubMed
    Score: 0.553
  10. Brown GC, Heneka MT. The endotoxin hypothesis of Alzheimer's disease. Mol Neurodegener. 2024 Apr 01; 19(1):30.
    View in: PubMed
    Score: 0.552
  11. Heneka MT. ApoE4 makes microglia trem2bling. Neuron. 2023 01 18; 111(2):142-144.
    View in: PubMed
    Score: 0.508
  12. Teipel SJ, Dyrba M, Ballarini T, Brosseron F, Bruno D, Buerger K, Cosma NC, Dechent P, Dobisch L, D?zel E, Ewers M, Fliessbach K, Haynes JD, Janowitz D, Kilimann I, Laske C, Maier F, Metzger CD, Munk MH, Peters O, Pomara N, Preis L, Priller J, Ram?rez A, Roy N, Scheffler K, Schneider A, Schott BH, Spottke A, Spruth EJ, Wagner M, Wiltfang J, Jessen F, Heneka MT. Association of Cholinergic Basal Forebrain Volume and Functional Connectivity with Markers of Inflammatory Response in the Alzheimer's Disease Spectrum. J Alzheimers Dis. 2022; 85(3):1267-1282.
    View in: PubMed
    Score: 0.472
  13. Kummer MP, Ising C, Kummer C, Sarlus H, Griep A, Vieira-Saecker A, Schwartz S, Halle A, Br?ckner M, H?ndler K, Schultze JL, Beyer M, Latz E, Heneka MT. Microglial PD-1 stimulation by astrocytic PD-L1 suppresses neuroinflammation and Alzheimer's disease pathology. EMBO J. 2021 12 15; 40(24):e108662.
    View in: PubMed
    Score: 0.469
  14. Bettcher BM, Tansey MG, Doroth?e G, Heneka MT. Peripheral and central immune system crosstalk in Alzheimer disease - a research prospectus. Nat Rev Neurol. 2021 11; 17(11):689-701.
    View in: PubMed
    Score: 0.463
  15. Brosseron F, Kleemann K, Kolbe CC, Santarelli F, Castro-Gomez S, Tacik P, Latz E, Jessen F, Heneka MT. Interrelations of Alzheimer?s disease candidate biomarkers neurogranin, fatty acid-binding protein 3 and ferritin to neurodegeneration and neuroinflammation. J Neurochem. 2021 06; 157(6):2210-2224.
    View in: PubMed
    Score: 0.432
  16. Villacampa N, Heneka MT. Microglia in Alzheimer's disease: Local heroes! J Exp Med. 2020 04 06; 217(4).
    View in: PubMed
    Score: 0.419
  17. McManus RM, Heneka MT. T cells in Alzheimer's disease: space invaders. Lancet Neurol. 2020 04; 19(4):285-287.
    View in: PubMed
    Score: 0.417
  18. Heneka MT. An immune-cell signature marks the brain in Alzheimer's disease. Nature. 2020 01; 577(7790):322-323.
    View in: PubMed
    Score: 0.411
  19. Venegas C, Heneka MT. Inflammasome-mediated innate immunity in Alzheimer's disease. FASEB J. 2019 12; 33(12):13075-13084.
    View in: PubMed
    Score: 0.407
  20. Wijasa TS, Sylvester M, Brocke-Ahmadinejad N, Schwartz S, Santarelli F, Gieselmann V, Klockgether T, Brosseron F, Heneka MT. Quantitative proteomics of synaptosome S-nitrosylation in Alzheimer's disease. J Neurochem. 2020 03; 152(6):710-726.
    View in: PubMed
    Score: 0.406
  21. Castro-Gomez S, Binder J, Heneka MT. [Neuroinflammation as motor of Alzheimer's disease]. Nervenarzt. 2019 Sep; 90(9):898-906.
    View in: PubMed
    Score: 0.402
  22. Tejera D, Mercan D, Sanchez-Caro JM, Hanan M, Greenberg D, Soreq H, Latz E, Golenbock D, Heneka MT. Systemic inflammation impairs microglial A? clearance through NLRP3 inflammasome. EMBO J. 2019 09 02; 38(17):e101064.
    View in: PubMed
    Score: 0.399
  23. Herrera-Rivero M, Santarelli F, Brosseron F, Kummer MP, Heneka MT. Dysregulation of TLR5 and TAM Ligands in the Alzheimer's Brain as Contributors to Disease Progression. Mol Neurobiol. 2019 Sep; 56(9):6539-6550.
    View in: PubMed
    Score: 0.388
  24. Tejera D, Heneka MT. In Vivo Phagocytosis Analysis of Amyloid Beta. Methods Mol Biol. 2019; 2034:287-292.
    View in: PubMed
    Score: 0.384
  25. Brosseron F, Trasch?tz A, Widmann CN, Kummer MP, Tacik P, Santarelli F, Jessen F, Heneka MT. Characterization and clinical use of inflammatory cerebrospinal fluid protein markers in Alzheimer's disease. Alzheimers Res Ther. 2018 02 26; 10(1):25.
    View in: PubMed
    Score: 0.362
  26. Dansokho C, Heneka MT. Neuroinflammatory responses in Alzheimer's disease. J Neural Transm (Vienna). 2018 05; 125(5):771-779.
    View in: PubMed
    Score: 0.357
  27. Venegas C, Kumar S, Franklin BS, Dierkes T, Brinkschulte R, Tejera D, Vieira-Saecker A, Schwartz S, Santarelli F, Kummer MP, Griep A, Gelpi E, Beilharz M, Riedel D, Golenbock DT, Geyer M, Walter J, Latz E, Heneka MT. Microglia-derived ASC specks cross-seed amyloid-? in Alzheimer's disease. Nature. 2017 12 20; 552(7685):355-361.
    View in: PubMed
    Score: 0.357
  28. Sarlus H, Heneka MT. Microglia in Alzheimer's disease. J Clin Invest. 2017 Sep 01; 127(9):3240-3249.
    View in: PubMed
    Score: 0.350
  29. McManus RM, Heneka MT. Role of neuroinflammation in neurodegeneration: new insights. Alzheimers Res Ther. 2017 Mar 04; 9(1):14.
    View in: PubMed
    Score: 0.338
  30. Heneka MT. Inflammasome activation and innate immunity in Alzheimer's disease. Brain Pathol. 2017 03; 27(2):220-222.
    View in: PubMed
    Score: 0.338
  31. Venegas C, Heneka MT. Danger-associated molecular patterns in Alzheimer's disease. J Leukoc Biol. 2017 01; 101(1):87-98.
    View in: PubMed
    Score: 0.329
  32. Tejera D, Heneka MT. Microglia in Alzheimer's disease: the good, the bad and the ugly. Curr Alzheimer Res. 2016; 13(4):370-80.
    View in: PubMed
    Score: 0.312
  33. Heneka MT, Carson MJ, El Khoury J, Landreth GE, Brosseron F, Feinstein DL, Jacobs AH, Wyss-Coray T, Vitorica J, Ransohoff RM, Herrup K, Frautschy SA, Finsen B, Brown GC, Verkhratsky A, Yamanaka K, Koistinaho J, Latz E, Halle A, Petzold GC, Town T, Morgan D, Shinohara ML, Perry VH, Holmes C, Bazan NG, Brooks DJ, Hunot S, Joseph B, Deigendesch N, Garaschuk O, Boddeke E, Dinarello CA, Breitner JC, Cole GM, Golenbock DT, Kummer MP. Neuroinflammation in Alzheimer's disease. Lancet Neurol. 2015 Apr; 14(4):388-405.
    View in: PubMed
    Score: 0.296
  34. Heneka MT, Golenbock DT, Latz E. Innate immunity in Alzheimer's disease. Nat Immunol. 2015 Mar; 16(3):229-36.
    View in: PubMed
    Score: 0.294
  35. Brosseron F, Krauthausen M, Kummer M, Heneka MT. Body fluid cytokine levels in mild cognitive impairment and Alzheimer's disease: a comparative overview. Mol Neurobiol. 2014 Oct; 50(2):534-44.
    View in: PubMed
    Score: 0.274
  36. Heneka MT, Kummer MP, Stutz A, Delekate A, Schwartz S, Vieira-Saecker A, Griep A, Axt D, Remus A, Tzeng TC, Gelpi E, Halle A, Korte M, Latz E, Golenbock DT. NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice. Nature. 2013 Jan 31; 493(7434):674-8.
    View in: PubMed
    Score: 0.252
  37. Yamanaka M, Ishikawa T, Griep A, Axt D, Kummer MP, Heneka MT. PPAR?/RXRa-induced and CD36-mediated microglial amyloid-? phagocytosis results in cognitive improvement in amyloid precursor protein/presenilin 1 mice. J Neurosci. 2012 Nov 28; 32(48):17321-31.
    View in: PubMed
    Score: 0.251
  38. Kummer MP, H?lsmann C, Hermes M, Axt D, Heneka MT. Nitric oxide decreases the enzymatic activity of insulin degrading enzyme in APP/PS1 mice. J Neuroimmune Pharmacol. 2012 Mar; 7(1):165-72.
    View in: PubMed
    Score: 0.236
  39. Rey NL, Jardanhazi-Kurutz D, Terwel D, Kummer MP, Jourdan F, Didier A, Heneka MT. Locus coeruleus degeneration exacerbates olfactory deficits in APP/PS1 transgenic mice. Neurobiol Aging. 2012 Feb; 33(2):426.e1-11.
    View in: PubMed
    Score: 0.219
  40. Heneka MT, O'Banion MK, Terwel D, Kummer MP. Neuroinflammatory processes in Alzheimer's disease. J Neural Transm (Vienna). 2010 Aug; 117(8):919-47.
    View in: PubMed
    Score: 0.213
  41. Heneka MT, Nadrigny F, Regen T, Martinez-Hernandez A, Dumitrescu-Ozimek L, Terwel D, Jardanhazi-Kurutz D, Walter J, Kirchhoff F, Hanisch UK, Kummer MP. Locus ceruleus controls Alzheimer's disease pathology by modulating microglial functions through norepinephrine. Proc Natl Acad Sci U S A. 2010 Mar 30; 107(13):6058-63.
    View in: PubMed
    Score: 0.208
  42. Landreth G, Jiang Q, Mandrekar S, Heneka M. PPARgamma agonists as therapeutics for the treatment of Alzheimer's disease. Neurotherapeutics. 2008 Jul; 5(3):481-9.
    View in: PubMed
    Score: 0.185
  43. Heneka MT, O'Banion MK. Inflammatory processes in Alzheimer's disease. J Neuroimmunol. 2007 Mar; 184(1-2):69-91.
    View in: PubMed
    Score: 0.167
  44. Sastre M, Klockgether T, Heneka MT. Contribution of inflammatory processes to Alzheimer's disease: molecular mechanisms. Int J Dev Neurosci. 2006 Apr-May; 24(2-3):167-76.
    View in: PubMed
    Score: 0.157
  45. Heneka MT, Ramanathan M, Jacobs AH, Dumitrescu-Ozimek L, Bilkei-Gorzo A, Debeir T, Sastre M, Galldiks N, Zimmer A, Hoehn M, Heiss WD, Klockgether T, Staufenbiel M. Locus ceruleus degeneration promotes Alzheimer pathogenesis in amyloid precursor protein 23 transgenic mice. J Neurosci. 2006 Feb 01; 26(5):1343-54.
    View in: PubMed
    Score: 0.157
  46. H?ll M, Berger M, Heneka M. Disease-modifying therapies in Alzheimer's disease: how far have we come? Drugs. 2006; 66(16):2075-93.
    View in: PubMed
    Score: 0.156
  47. Heneka MT, Sastre M, Dumitrescu-Ozimek L, Hanke A, Dewachter I, Kuiperi C, O'Banion K, Klockgether T, Van Leuven F, Landreth GE. Acute treatment with the PPARgamma agonist pioglitazone and ibuprofen reduces glial inflammation and Abeta1-42 levels in APPV717I transgenic mice. Brain. 2005 Jun; 128(Pt 6):1442-53.
    View in: PubMed
    Score: 0.148
  48. Kuhn E, Klinger HM, Amariglio RE, Wagner M, Jessen F, D?zel E, Heneka MT, Ch?telat G, Rentz DM, Sperling RA, Ebenau JL, Butterbrod E, Van Der Flier WM, Sikkes SAM, Teunnissen CE, Van Harten AC, Van De Giessen EM, Rami L, Tort A, S?nchez Benavides G, Gifford KA, Van Hulle C, Buckley RF. SCD-plus features and AD biomarkers in cognitively unimpaired samples: A meta-analytic approach for nine cohort studies. Alzheimers Dement. 2025 May; 21(5):e14307.
    View in: PubMed
    Score: 0.147
  49. Schneider LS, Freiesleben SD, van Breukelen G, Wang X, Brosseron F, Heneka MT, Teipel S, Kleineidam L, Stark M, Roy-Kluth N, Wagner M, Spottke A, Schmid M, Roeske S, Laske C, Munk MH, Perneczky R, Rauchmann BS, Buerger K, Janowitz D, D?zel E, Glanz W, Jessen F, Rostamzadeh A, Wiltfang J, Bartels C, Kilimann I, Schneider A, Fliessbach K, Priller J, Spruth EJ, Hellmann-Regen J, Peters O. Linking higher amyloid beta 1-38 (A?(1-38)) levels to reduced Alzheimer's disease progression risk. Alzheimers Dement. 2025 Feb; 21(2):e14545.
    View in: PubMed
    Score: 0.146
  50. Kloske CM, Mahinrad S, Barnum CJ, Batista AF, Bradshaw EM, Butts B, Carrillo MC, Chakrabarty P, Chen X, Craft S, Da Mesquita S, Dabin LC, Devanand D, Duran-Laforet V, Elyaman W, Evans EE, Fitzgerald-Bocarsly P, Foley KE, Harms AS, Heneka MT, Hong S, Huang YA, Jackvony S, Lai L, Guen YL, Lemere CA, Liddelow SA, Martin-Pe?a A, Orr AG, Quintana FJ, Ramey GD, Rexach JE, Rizzo SJS, Sexton C, Tang AS, Torrellas JG, Tsai AP, van Olst L, Walker KA, Wharton W, Tansey MG, Wilcock DM. Advancements in Immunity and Dementia Research: Highlights from the 2023 AAIC Advancements: Immunity Conference. Alzheimers Dement. 2025 Jan; 21(1):e14291.
    View in: PubMed
    Score: 0.145
  51. Schrempel S, Kottwitz AK, Piechotta A, Gnoth K, B?schgens L, Hartlage-R?bsamen M, Morawski M, Schenk M, Kleinschmidt M, Serrano GE, Beach TG, Rostagno A, Ghiso J, Heneka MT, Walter J, Wirths O, Schilling S, Ro?ner S. Identification of isoAsp7-A? as a major A? variant in Alzheimer's disease, dementia with Lewy bodies and vascular dementia. Acta Neuropathol. 2024 Dec 03; 148(1):78.
    View in: PubMed
    Score: 0.145
  52. Stark M, Wagner M, Kuhn E, B?rger K, D?zel E, Hellmann-Regen J, Heneka MT, Laske C, Perneczky R, Peters O, Priller J, Schmid M, Schneider A, Spottke A, Teipel S, Wiltfang J, Jessen F, Kleineidam L. Clinical Manifestations. Alzheimers Dement. 2024 Dec; 20 Suppl 3:e091377.
    View in: PubMed
    Score: 0.145
  53. Vockert N, Machts J, Kleineidam L, Nemali A, Incesoy EI, Bernal J, Sch?tze H, Yakupov R, Peters O, Gref D, Schneider LS, Preis L, Priller J, Spruth EJ, Altenstein S, Schneider A, Fliessbach K, Wiltfang J, Rostamzadeh A, Glanz W, Teipel S, Kilimann I, Goerss D, Laske C, Munk MH, Spottke A, Roy N, Heneka MT, Brosseron F, Wagner M, Wolfsgruber S, Dobisch L, Dechent P, Hetzer S, Scheffler K, Zeidman P, Stern Y, Schott BH, Jessen F, D?zel E, Maass A, Ziegler G. Cognitive reserve against Alzheimer's pathology is linked to brain activity during memory formation. Nat Commun. 2024 11 13; 15(1):9815.
    View in: PubMed
    Score: 0.144
  54. Soch J, Richter A, Kizilirmak JM, Sch?tze H, Ziegler G, Altenstein S, Brosseron F, Dechent P, Fliessbach K, Freiesleben SD, Glanz W, Gref D, Heneka MT, Hetzer S, Incesoy EI, Kilimann I, Kimmich O, Kleineidam L, Kuhn E, Laske C, Lohse A, L?sebrink F, Munk MH, Peters O, Preis L, Priller J, Ramirez A, Roeske S, Rostamzadeh A, Roy-Kluth N, Scheffler K, Schmid M, Schneider A, Spottke A, Spruth EJ, Teipel S, Wiltfang J, Jessen F, Wagner M, D?zel E, Schott BH. Single-value brain activity scores reflect both severity and risk across the Alzheimer's continuum. Brain. 2024 Nov 04; 147(11):3789-3803.
    View in: PubMed
    Score: 0.144
  55. Menze I, Bernal J, Kaya P, Aki ?, Pfister M, Geisend?rfer J, Yakupov R, Coello RD, Vald?s-Hern?ndez MDC, Heneka MT, Brosseron F, Schmid MC, Glanz W, Incesoy EI, Butryn M, Rostamzadeh A, Meiberth D, Peters O, Preis L, Lammerding D, Gref D, Priller J, Spruth EJ, Altenstein S, Lohse A, Hetzer S, Schneider A, Fliessbach K, Kimmich O, Vogt IR, Wiltfang J, Bartels C, Schott BH, Hansen N, Dechent P, Buerger K, Janowitz D, Perneczky R, Rauchmann BS, Teipel S, Kilimann I, Goerss D, Laske C, Munk MH, Sanzenbacher C, Hinderer P, Scheffler K, Spottke A, Roy-Kluth N, L?sebrink F, Neumann K, Wardlaw J, Jessen F, Schreiber S, D?zel E, Ziegler G. Perivascular space enlargement accelerates in ageing and Alzheimer's disease pathology: evidence from a three-year longitudinal multicentre study. Alzheimers Res Ther. 2024 Oct 31; 16(1):242.
    View in: PubMed
    Score: 0.144
  56. Lista S, Imbimbo BP, Grasso M, Fidilio A, Emanuele E, Minoretti P, L?pez-Ortiz S, Mart?n-Hern?ndez J, Gabelle A, Caruso G, Malaguti M, Melchiorri D, Santos-Lozano A, Imbimbo C, Heneka MT, Caraci F. Tracking neuroinflammatory biomarkers in Alzheimer's disease: a strategy for individualized therapeutic approaches? J Neuroinflammation. 2024 Jul 30; 21(1):187.
    View in: PubMed
    Score: 0.141
  57. Baumeister H, Vogel JW, Insel PS, Kleineidam L, Wolfsgruber S, Stark M, Gellersen HM, Yakupov R, Schmid MC, L?sebrink F, Brosseron F, Ziegler G, Freiesleben SD, Preis L, Schneider LS, Spruth EJ, Altenstein S, Lohse A, Fliessbach K, Vogt IR, Bartels C, Schott BH, Rostamzadeh A, Glanz W, Incesoy EI, Butryn M, Janowitz D, Rauchmann BS, Kilimann I, Goerss D, Munk MH, Hetzer S, Dechent P, Ewers M, Scheffler K, Wuestefeld A, Strandberg O, van Westen D, Mattsson-Carlgren N, Janelidze S, Stomrud E, Palmqvist S, Spottke A, Laske C, Teipel S, Perneczky R, Buerger K, Schneider A, Priller J, Peters O, Ramirez A, Wiltfang J, Heneka MT, Wagner M, D?zel E, Jessen F, Hansson O, Berron D. A generalizable data-driven model of atrophy heterogeneity and progression in memory clinic settings. Brain. 2024 Jul 05; 147(7):2400-2413.
    View in: PubMed
    Score: 0.140
  58. Vogelgsang J, Hansen N, Stark M, Wagner M, Klafki H, Morgado BM, Jahn-Brodmann A, Schott B, Esselmann H, Bauer C, Schuchhardt J, Kleineidam L, Wolfsgruber S, Peters O, Schneider LS, Wang X, Menne F, Priller J, Spruth E, Altenstein S, Lohse A, Schneider A, Fliessbach K, Vogt I, Bartels C, Jessen F, Rostamzadeh A, Duezel E, Glanz W, Incesoy E, Butryn M, Buerger K, Janowitz D, Ewers M, Perneczky R, Rauchmann B, Guersel S, Teipel S, Kilimann I, Goerss D, Laske C, Munk M, Sanzenbacher C, Spottke A, Roy-Kluth N, Heneka M, Brosseron F, Ramierez A, Schmid M, Wiltfang J. Plasma amyloid beta X-42/X-40 ratio and cognitive decline in suspected early and preclinical Alzheimer's disease. Alzheimers Dement. 2024 08; 20(8):5132-5142.
    View in: PubMed
    Score: 0.140
  59. Deike K, Decker A, Scheyhing P, Harten J, Zimmermann N, Paech D, Peters O, Freiesleben SD, Schneider LS, Preis L, Priller J, Spruth E, Altenstein S, Lohse A, Fliessbach K, Kimmich O, Wiltfang J, Bartels C, Hansen N, Jessen F, Rostamzadeh A, D?zel E, Glanz W, Incesoy EI, Butryn M, Buerger K, Janowitz D, Ewers M, Perneczky R, Rauchmann BS, Teipel S, Kilimann I, Goerss D, Laske C, Munk MH, Spottke A, Roy N, Wagner M, Roeske S, Heneka MT, Brosseron F, Ramirez A, Dobisch L, Wolfsgruber S, Kleineidam L, Yakupov R, Stark M, Schmid MC, Berger M, Hetzer S, Dechent P, Scheffler K, Petzold GC, Schneider A, Effland A, Radbruch A. Machine Learning-Based Perivascular Space Volumetry in Alzheimer Disease. Invest Radiol. 2024 Sep 01; 59(9):667-676.
    View in: PubMed
    Score: 0.139
  60. Ferguson CM, Hildebrand S, Godinho BMDC, Buchwald J, Echeverria D, Coles A, Grigorenko A, Vangjeli L, Sousa J, McHugh N, Hassler M, Santarelli F, Heneka MT, Rogaev E, Khvorova A. Silencing Apoe with divalent-siRNAs improves amyloid burden and activates immune response pathways in Alzheimer's disease. Alzheimers Dement. 2024 04; 20(4):2632-2652.
    View in: PubMed
    Score: 0.137
  61. Talavera And?jar B, Mary A, Venegas C, Cheng T, Zaslavsky L, Bolton EE, Heneka MT, Schymanski EL. Can Small Molecules Provide Clues on Disease Progression in Cerebrospinal Fluid from Mild Cognitive Impairment and Alzheimer's Disease Patients? Environ Sci Technol. 2024 Mar 05; 58(9):4181-4192.
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    Score: 0.137
  62. Hayek D, Ziegler G, Kleineidam L, Brosseron F, Nemali A, Vockert N, Ravichandran KA, Betts MJ, Peters O, Schneider LS, Wang X, Priller J, Altenstein S, Schneider A, Fliessbach K, Wiltfang J, Bartels C, Rostamzadeh A, Glanz W, Buerger K, Janowitz D, Perneczky R, Rauchmann BS, Teipel S, Kilimann I, Laske C, Mengel D, Synofzik M, Munk MH, Spottke A, Roy N, Roeske S, Kuhn E, Ramirez A, Dobisch L, Schmid M, Berger M, Wolfsgruber S, Yakupov R, Hetzer S, Dechent P, Ewers M, Scheffler K, Schott BH, Schreiber S, Orellana A, de Rojas I, Marqui? M, Boada M, Sotolongo O, Gonz?lez PG, Puerta R, D?zel E, Jessen F, Wagner M, Ruiz A, Heneka MT, Maass A. Different inflammatory signatures based on CSF biomarkers relate to preserved or diminished brain structure and cognition. Mol Psychiatry. 2024 Apr; 29(4):992-1004.
    View in: PubMed
    Score: 0.136
  63. Sannemann L, Bartels C, Brosseron F, Buerger K, Fliessbach K, Freiesleben SD, Frommann I, Glanz W, Heneka MT, Janowitz D, Kilimann I, Kleineidam L, Lammerding D, Laske C, Munk MHJ, Perneczky R, Peters O, Priller J, Rauchmann BS, Rostamzadeh A, Roy-Kluth N, Schild AK, Schneider A, Schneider LS, Spottke A, Spruth EJ, Teipel S, Wagner M, Wiltfang J, Wolfsgruber S, Duezel E, Jessen F. Symptomatic Clusters Related to Amyloid Positivity in Cognitively Unimpaired Individuals. J Alzheimers Dis. 2024; 100(1):193-205.
    View in: PubMed
    Score: 0.136
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  87. Islam MR, Kaurani L, Berulava T, Heilbronner U, Budde M, Centeno TP, Elerdashvili V, Zafieriou MP, Benito E, Sertel SM, Goldberg M, Senner F, Kalman JL, Burkhardt S, Oepen AS, Sakib MS, Kerimoglu C, Wirths O, Bickeb?ller H, Bartels C, Brosseron F, Buerger K, Cosma NC, Fliessbach K, Heneka MT, Janowitz D, Kilimann I, Kleinedam L, Laske C, Metzger CD, Munk MH, Perneczky R, Peters O, Priller J, Rauchmann BS, Roy N, Schneider A, Spottke A, Spruth EJ, Teipel S, Tscheuschler M, Wagner M, Wiltfang J, D?zel E, Jessen F, Rizzoli SO, Zimmermann WH, Schulze TG, Falkai P, Sananbenesi F, Fischer A. A microRNA signature that correlates with cognition and is a target against cognitive decline. EMBO Mol Med. 2021 11 08; 13(11):e13659.
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  88. Rauchmann BS, Ersoezlue E, Stoecklein S, Keeser D, Brosseron F, Buerger K, Dechent P, Dobisch L, Ertl-Wagner B, Fliessbach K, Haynes JD, Heneka MT, Incesoy EI, Janowitz D, Kilimann I, Laske C, Metzger CD, Munk MH, Peters O, Priller J, Ramirez A, Roeske S, Roy N, Scheffler K, Schneider A, Spottke A, Spruth EJ, Teipel S, Tscheuschler M, Vukovich R, Wagner M, Wiltfang J, Yakupov R, Duezel E, Jessen F, Perneczky R. Resting-State Network Alterations Differ between Alzheimer's Disease Atrophy Subtypes. Cereb Cortex. 2021 10 01; 31(11):4901-4915.
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  89. Joshi P, Riffel F, Satoh K, Enomoto M, Qamar S, Scheiblich H, Villacampa N, Kumar S, Theil S, Parhizkar S, Haass C, Heneka MT, Fraser PE, St George-Hyslop P, Walter J. Differential interaction with TREM2 modulates microglial uptake of modified A? species. Glia. 2021 12; 69(12):2917-2932.
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  90. Bergstr?m S, Remnest?l J, Yousef J, Olofsson J, Markaki I, Carvalho S, Corvol JC, Kultima K, Kilander L, L?wenmark M, Ingelsson M, Blennow K, Zetterberg H, Nellg?rd B, Brosseron F, Heneka MT, Bosch B, Sanchez-Valle R, M?nberg A, Svenningsson P, Nilsson P. Multi-cohort profiling reveals elevated CSF levels of brain-enriched proteins in Alzheimer's disease. Ann Clin Transl Neurol. 2021 07; 8(7):1456-1470.
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  91. de Rojas I, Moreno-Grau S, Tesi N, Grenier-Boley B, Andrade V, Jansen IE, Pedersen NL, Stringa N, Zettergren A, Hern?ndez I, Montrreal L, Ant?nez C, Antonell A, Tankard RM, Bis JC, Sims R, Bellenguez C, Quintela I, Gonz?lez-Perez A, Calero M, Franco-Mac?as E, Mac?as J, Blesa R, Cervera-Carles L, Men?ndez-Gonz?lez M, Frank-Garc?a A, Royo JL, Moreno F, Huerto Vilas R, Baquero M, Diez-Fairen M, Lage C, Garc?a-Madrona S, Garc?a-Gonz?lez P, Alarc?n-Mart?n E, Valero S, Sotolongo-Grau O, Ullgren A, Naj AC, Lemstra AW, Benaque A, P?rez-Cord?n A, Benussi A, R?bano A, Padovani A, Squassina A, de Mendon?a A, Arias Pastor A, Kok AAL, Meggy A, Pastor AB, Espinosa A, Corma-G?mez A, Mart?n Montes A, Sanabria ?, DeStefano AL, Schneider A, Haapasalo A, Kinhult St?hlbom A, Tybj?rg-Hansen A, Hartmann AM, Spottke A, Corbat?n-Anchuelo A, Rongve A, Borroni B, Arosio B, Nacmias B, Nordestgaard BG, Kunkle BW, Charbonnier C, Abdelnour C, Masullo C, Mart?nez Rodr?guez C, Mu?oz-Fernandez C, Dufouil C, Graff C, Ferreira CB, Chillotti C, Reynolds CA, Fenoglio C, Van Broeckhoven C, Clark C, Pisanu C, Satizabal CL, Holmes C, Buiza-Rueda D, Aarsland D, Rujescu D, Alcolea D, Galimberti D, Wallon D, Seripa D, Gr?nblatt E, Dardiotis E, D?zel E, Scarpini E, Conti E, Rubino E, Gelpi E, Rodriguez-Rodriguez E, Duron E, Boerwinkle E, Ferri E, Tagliavini F, K???kali F, Pasquier F, Sanchez-Garcia F, Mangialasche F, Jessen F, Nicolas G, Selb?k G, Ortega G, Ch?ne G, Hadjigeorgiou G, Rossi G, Spalletta G, Giaccone G, Grande G, Binetti G, Papenberg G, Hampel H, Bailly H, Zetterberg H, Soininen H, Karlsson IK, Alvarez I, Appollonio I, Giegling I, Skoog I, Saltvedt I, Rainero I, Rosas Allende I, Hort J, Diehl-Schmid J, Van Dongen J, Vidal JS, Lehtisalo J, Wiltfang J, Thomassen JQ, Kornhuber J, Haines JL, Vogelgsang J, Pineda JA, Fortea J, Popp J, Deckert J, Buerger K, Morgan K, Flie?bach K, Sleegers K, Molina-Porcel L, Kilander L, Weinhold L, Farrer LA, Wang LS, Kleineidam L, Farotti L, Parnetti L, Tremolizzo L, Hausner L, Benussi L, Froelich L, Ikram MA, Deniz-Naranjo MC, Tsolaki M, Rosende-Roca M, L?wenmark M, Hulsman M, Spallazzi M, Pericak-Vance MA, Esiri M, Bernal S?nchez-Arjona M, Dalmasso MC, Mart?nez-Larrad MT, Arcaro M, N?then MM, Fern?ndez-Fuertes M, Dichgans M, Ingelsson M, Herrmann MJ, Scherer M, Vyhnalek M, Kosmidis MH, Yannakoulia M, Schmid M, Ewers M, Heneka MT, Wagner M, Scamosci M, Kivipelto M, Hiltunen M, Zulaica M, Alegret M, Fornage M, Roberto N, van Schoor NM, Seidu NM, Banaj N, Armstrong NJ, Scarmeas N, Scherbaum N, Goldhardt O, Hanon O, Peters O, Skrobot OA, Quenez O, Lerch O, Boss? P, Caffarra P, Dionigi Rossi P, Sakka P, Mecocci P, Hoffmann P, Holmans PA, Fischer P, Riederer P, Yang Q, Marshall R, Kalaria RN, Mayeux R, Vandenberghe R, Cecchetti R, Ghidoni R, Frikke-Schmidt R, Sorbi S, H?gg S, Engelborghs S, Helisalmi S, Botne Sando S, Kern S, Archetti S, Boschi S, Fostinelli S, Gil S, Mendoza S, Mead S, Ciccone S, Djurovic S, Heilmann-Heimbach S, Riedel-Heller S, Kuulasmaa T, Del Ser T, Lebouvier T, Polak T, Ngandu T, Grimmer T, Bessi V, Escott-Price V, Giedraitis V, Deramecourt V, Maier W, Jian X, Pijnenburg YAL, Kehoe PG, Garcia-Ribas G, S?nchez-Juan P, Pastor P, P?rez-Tur J, Pi?ol-Ripoll G, Lopez de Munain A, Garc?a-Alberca JM, Bullido MJ, ?lvarez V, Lle? A, Real LM, Mir P, Medina M, Scheltens P, Holstege H, Marqui? M, S?ez ME, Carracedo ?, Amouyel P, Schellenberg GD, Williams J, Seshadri S, van Duijn CM, Mather KA, S?nchez-Valle R, Serrano-R?os M, Orellana A, T?rraga L, Blennow K, Huisman M, Andreassen OA, Posthuma D, Clarim?n J, Boada M, van der Flier WM, Ramirez A, Lambert JC, van der Lee SJ, Ruiz A. Common variants in Alzheimer's disease and risk stratification by polygenic risk scores. Nat Commun. 2021 06 07; 12(1):3417.
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  92. Herdick M, Dyrba M, Fritz HJ, Altenstein S, Ballarini T, Brosseron F, Buerger K, Can Cetindag A, Dechent P, Dobisch L, Duezel E, Ertl-Wagner B, Fliessbach K, Dawn Freiesleben S, Frommann I, Glanz W, Dylan Haynes J, Heneka MT, Janowitz D, Kilimann I, Laske C, Metzger CD, Munk MH, Peters O, Priller J, Roy N, Scheffler K, Schneider A, Spottke A, Jakob Spruth E, Tscheuschler M, Vukovich R, Wiltfang J, Jessen F, Teipel S, Grothe MJ. Multimodal MRI analysis of basal forebrain structure and function across the Alzheimer's disease spectrum. Neuroimage Clin. 2020; 28:102495.
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  93. Sannemann L, Schild AK, Altenstein S, Bartels C, Brosseron F, Buerger K, Cosma NC, Fliessbach K, Freiesleben SD, Glanz W, Heneka MT, Janowitz D, Kilimann I, Kobeleva X, Laske C, Metzger CD, Munk MHJ, Perneczky R, Peters O, Polcher A, Priller J, Rauchmann B, R?sch C, Rudolph J, Schneider A, Spottke A, Spruth EJ, Teipel S, Vukovich R, Wagner M, Wiltfang J, Wolfsgruber S, Duezel E, Jessen F. Neuropsychiatric symptoms in at-risk groups for AD dementia and their association with worry and AD biomarkers-results from the DELCODE study. Alzheimers Res Ther. 2020 10 16; 12(1):131.
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  94. Finsterwalder S, Vlegels N, Gesierich B, Araque Caballero M?, Weaver NA, Franzmeier N, Georgakis MK, Konieczny MJ, Koek HL, Karch CM, Graff-Radford NR, Salloway S, Oh H, Allegri RF, Chhatwal JP, Jessen F, D?zel E, Dobisch L, Metzger C, Peters O, Incesoy EI, Priller J, Spruth EJ, Schneider A, Flie?bach K, Buerger K, Janowitz D, Teipel SJ, Kilimann I, Laske C, Buchmann M, Heneka MT, Brosseron F, Spottke A, Roy N, Ertl-Wagner B, Scheffler K, Seo SW, Kim Y, Na DL, Kim HJ, Jang H, Ewers M, Levin J, Schmidt R, Pasternak O, Dichgans M, Biessels GJ, Duering M. Small vessel disease more than Alzheimer's disease determines diffusion MRI alterations in memory clinic patients. Alzheimers Dement. 2020 11; 16(11):1504-1514.
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  95. Schr?der N, Schaffrath A, Welter JA, Putzka T, Griep A, Ziegler P, Brandt E, Samer S, Heneka MT, Kaddatz H, Zhan J, Kipp E, Pufe T, Tauber SC, Kipp M, Brandenburg LO. Inhibition of formyl peptide receptors improves the outcome in a mouse model of Alzheimer disease. J Neuroinflammation. 2020 Apr 24; 17(1):131.
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  96. Kleineidam L, Chouraki V, Pr?chnicki T, van der Lee SJ, Madrid-M?rquez L, Wagner-Thelen H, Karaca I, Weinhold L, Wolfsgruber S, Boland A, Martino Adami PV, Lewczuk P, Popp J, Brosseron F, Jansen IE, Hulsman M, Kornhuber J, Peters O, Berr C, Heun R, Fr?lich L, Tzourio C, Dartigues JF, H?ll M, Espinosa A, Hern?ndez I, de Rojas I, Orellana A, Valero S, Stringa N, van Schoor NM, Huisman M, Scheltens P, R?ther E, Deleuze JF, Wiltfang J, Tarraga L, Schmid M, Scherer M, Riedel-Heller S, Heneka MT, Amouyel P, Jessen F, Boada M, Maier W, Schneider A, Gonz?lez-P?rez A, van der Flier WM, Wagner M, Lambert JC, Holstege H, S?ez ME, Latz E, Ruiz A, Ramirez A. PLCG2 protective variant p.P522R modulates tau pathology and disease progression in patients with mild cognitive impairment. Acta Neuropathol. 2020 06; 139(6):1025-1044.
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  97. Itzhaki RF, Golde TE, Heneka MT, Readhead B. Do infections have a role in the pathogenesis of Alzheimer disease? Nat Rev Neurol. 2020 04; 16(4):193-197.
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  98. Brosseron F, Kolbe CC, Santarelli F, Carvalho S, Antonell A, Castro-Gomez S, Tacik P, Namasivayam AA, Mangone G, Schneider R, Latz E, W?llner U, Svenningsson P, S?nchez-Valle R, Molinuevo JL, Corvol JC, Heneka MT. Multicenter Alzheimer's and Parkinson's disease immune biomarker verification study. Alzheimers Dement. 2020 02; 16(2):292-304.
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  99. Mantile F, Capasso A, Villacampa N, Donnini M, Liguori GL, Constantin G, De Berardinis P, Heneka MT, Prisco A. Vaccination with (1-11)E2 in alum efficiently induces an antibody response to ?-amyloid without affecting brain ?-amyloid load and microglia activation in 3xTg mice. Aging Clin Exp Res. 2021 May; 33(5):1383-1387.
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  100. Webers A, Heneka MT, Gleeson PA. The role of innate immune responses and neuroinflammation in amyloid accumulation and progression of Alzheimer's disease. Immunol Cell Biol. 2020 01; 98(1):28-41.
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  101. Bertens D, Vos S, Kehoe P, Wolf H, Nobili F, Mendon?a A, van Rossum I, Hort J, Molinuevo JL, Heneka M, Petersen R, Scheltens P, Visser PJ. Use of mild cognitive impairment and prodromal AD/MCI due to AD in clinical care: a European survey. Alzheimers Res Ther. 2019 08 22; 11(1):74.
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  102. Miebach L, Wolfsgruber S, Polcher A, Peters O, Menne F, Luther K, Incesoy E, Priller J, Spruth E, Altenstein S, Buerger K, Catak C, Janowitz D, Perneczky R, Utecht J, Laske C, Buchmann M, Schneider A, Fliessbach K, Kalbhen P, Heneka MT, Brosseron F, Spottke A, Roy N, Teipel SJ, Kilimann I, Wiltfang J, Bartels C, D?zel E, Dobisch L, Metzger C, Meiberth D, Ramirez A, Jessen F, Wagner M. Which features of subjective cognitive decline are related to amyloid pathology? Findings from the DELCODE study. Alzheimers Res Ther. 2019 07 31; 11(1):66.
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  103. Esteve P, Rueda-Carrasco J, In?s Mateo M, Martin-Bermejo MJ, Draffin J, Pereyra G, Sandon?s ?, Crespo I, Moreno I, Aso E, Garcia-Esparcia P, Gomez-Tortosa E, R?bano A, Fortea J, Alcolea D, Lleo A, Heneka MT, Valpuesta JM, Esteban JA, Ferrer I, Dom?nguez M, Bovolenta P. Elevated levels of Secreted-Frizzled-Related-Protein 1 contribute to Alzheimer's disease pathogenesis. Nat Neurosci. 2019 08; 22(8):1258-1268.
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  104. Franzmeier N, Ren J, Damm A, Mont?-Rubio G, Boada M, Ruiz A, Ramirez A, Jessen F, D?zel E, Rodr?guez G?mez O, Benzinger T, Goate A, Karch CM, Fagan AM, McDade E, Buerger K, Levin J, Duering M, Dichgans M, Su?rez-Calvet M, Haass C, Gordon BA, Lim YY, Masters CL, Janowitz D, Catak C, Wolfsgruber S, Wagner M, Milz E, Moreno-Grau S, Teipel S, Grothe MJ, Kilimann I, Rossor M, Fox N, Laske C, Chhatwal J, Falkai P, Perneczky R, Lee JH, Spottke A, Boecker H, Brosseron F, Fliessbach K, Heneka MT, Nestor P, Peters O, Fuentes M, Menne F, Priller J, Spruth EJ, Franke C, Schneider A, Westerteicher C, Speck O, Wiltfang J, Bartels C, Araque Caballero M?, Metzger C, Bittner D, Salloway S, Danek A, Hassenstab J, Yakushev I, Schofield PR, Morris JC, Bateman RJ, Ewers M. The BDNFVal66Met SNP modulates the association between beta-amyloid and hippocampal disconnection in Alzheimer's disease. Mol Psychiatry. 2021 02; 26(2):614-628.
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  105. Wolfsgruber S, Molinuevo JL, Wagner M, Teunissen CE, Rami L, Coll-Padr?s N, Bouwman FH, Slot RER, Wesselman LMP, Peters O, Luther K, Buerger K, Priller J, Laske C, Teipel S, Spottke A, Heneka MT, D?zel E, Drzezga A, Wiltfang J, Sikkes SAM, van der Flier WM, Jessen F. Prevalence of abnormal Alzheimer's disease biomarkers in patients with subjective cognitive decline: cross-sectional comparison of three European memory clinic samples. Alzheimers Res Ther. 2019 01 17; 11(1):8.
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  106. Teipel SJ, Kuper-Smith JO, Bartels C, Brosseron F, Buchmann M, Buerger K, Catak C, Janowitz D, Dechent P, Dobisch L, Ertl-Wagner B, Flie?bach K, Haynes JD, Heneka MT, Kilimann I, Laske C, Li S, Menne F, Metzger CD, Priller J, Pross V, Ramirez A, Scheffler K, Schneider A, Spottke A, Spruth EJ, Wagner M, Wiltfang J, Wolfsgruber S, D?zel E, Jessen F, Dyrba M. Multicenter Tract-Based Analysis of Microstructural Lesions within the Alzheimer's Disease Spectrum: Association with Amyloid Pathology and Diagnostic Usefulness. J Alzheimers Dis. 2019; 72(2):455-465.
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  107. Hu X, Teunissen CE, Spottke A, Heneka MT, D?zel E, Peters O, Li S, Priller J, Buerger K, Teipel S, Laske C, Verfaillie SCJ, Barkhof F, Coll-Padr?s N, Rami L, Molinuevo JL, van der Flier WM, Jessen F. Smaller medial temporal lobe volumes in individuals with subjective cognitive decline and biomarker evidence of Alzheimer's disease-Data from three memory clinic studies. Alzheimers Dement. 2019 02; 15(2):185-193.
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  108. Tzeng TC, Hasegawa Y, Iguchi R, Cheung A, Caffrey DR, Thatcher EJ, Mao W, Germain G, Tamburro ND, Okabe S, Heneka MT, Latz E, Futai K, Golenbock DT. Inflammasome-derived cytokine IL18 suppresses amyloid-induced seizures in Alzheimer-prone mice. Proc Natl Acad Sci U S A. 2018 09 04; 115(36):9002-9007.
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  109. Unger MS, Marschallinger J, Kaindl J, Klein B, Johnson M, Khundakar AA, Ro?ner S, Heneka MT, Couillard-Despres S, Rockenstein E, Masliah E, Attems J, Aigner L. Doublecortin expression in CD8+ T-cells and microglia at sites of amyloid-? plaques: A potential role in shaping plaque pathology? Alzheimers Dement. 2018 08; 14(8):1022-1037.
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  110. Franzmeier N, D?zel E, Jessen F, Buerger K, Levin J, Duering M, Dichgans M, Haass C, Su?rez-Calvet M, Fagan AM, Paumier K, Benzinger T, Masters CL, Morris JC, Perneczky R, Janowitz D, Catak C, Wolfsgruber S, Wagner M, Teipel S, Kilimann I, Ramirez A, Rossor M, Jucker M, Chhatwal J, Spottke A, Boecker H, Brosseron F, Falkai P, Fliessbach K, Heneka MT, Laske C, Nestor P, Peters O, Fuentes M, Menne F, Priller J, Spruth EJ, Franke C, Schneider A, Kofler B, Westerteicher C, Speck O, Wiltfang J, Bartels C, Araque Caballero M?, Metzger C, Bittner D, Weiner M, Lee JH, Salloway S, Danek A, Goate A, Schofield PR, Bateman RJ, Ewers M. Left frontal hub connectivity delays cognitive impairment in autosomal-dominant and sporadic Alzheimer's disease. Brain. 2018 04 01; 141(4):1186-1200.
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  111. Enkirch SJ, Trasch?tz A, M?ller A, Widmann CN, Gielen GH, Heneka MT, Jurcoane A, Schild HH, Hattingen E. The ERICA Score: An MR Imaging-based Visual Scoring System for the Assessment of Entorhinal Cortex Atrophy in Alzheimer Disease. Radiology. 2018 Jul; 288(1):226-333.
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  114. Ardura-Fabregat A, Boddeke EWGM, Boza-Serrano A, Brioschi S, Castro-Gomez S, Ceyz?riat K, Dansokho C, Dierkes T, Gelders G, Heneka MT, Hoeijmakers L, Hoffmann A, Iaccarino L, Jahnert S, Kuhbandner K, Landreth G, Lonnemann N, L?schmann PA, McManus RM, Paulus A, Reemst K, Sanchez-Caro JM, Tiberi A, Van der Perren A, Vautheny A, Venegas C, Webers A, Weydt P, Wijasa TS, Xiang X, Yang Y. Targeting Neuroinflammation to Treat Alzheimer's Disease. CNS Drugs. 2017 12; 31(12):1057-1082.
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  115. Unger MS, Marschallinger J, Kaindl J, H?fling C, Rossner S, Heneka MT, Van der Linden A, Aigner L. Early Changes in Hippocampal Neurogenesis in Transgenic Mouse Models for Alzheimer's Disease. Mol Neurobiol. 2016 10; 53(8):5796-806.
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  116. Heneka MT, Nicotera P. Thoughts on Obesity and Brain Glucose. Cell. 2016 May 05; 165(4):773-5.
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  118. Bach JP, Gold M, Mengel D, Hattesohl A, Lubbe D, Schmid S, Tackenberg B, Rieke J, Maddula S, Baumbach JI, Nell C, Boeselt T, Michelis J, Alferink J, Heneka M, Oertel W, Jessen F, Janciauskiene S, Vogelmeier C, Dodel R, Koczulla AR. Measuring Compounds in Exhaled Air to Detect Alzheimer's Disease and Parkinson's Disease. PLoS One. 2015; 10(7):e0132227.
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  120. Krauthausen M, Kummer MP, Zimmermann J, Reyes-Irisarri E, Terwel D, Bulic B, Heneka MT, M?ller M. CXCR3 promotes plaque formation and behavioral deficits in an Alzheimer's disease model. J Clin Invest. 2015 Jan; 125(1):365-78.
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  122. Malhotra A, Younesi E, G?ndel M, M?ller B, Heneka MT, Hofmann-Apitius M. ADO: a disease ontology representing the domain knowledge specific to Alzheimer's disease. Alzheimers Dement. 2014 Mar; 10(2):238-46.
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  124. Kummer MP, Vogl T, Axt D, Griep A, Vieira-Saecker A, Jessen F, Gelpi E, Roth J, Heneka MT. Mrp14 deficiency ameliorates amyloid ? burden by increasing microglial phagocytosis and modulation of amyloid precursor protein processing. J Neurosci. 2012 Dec 05; 32(49):17824-9.
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  125. Rapic S, Backes H, Viel T, Kummer MP, Monfared P, Neumaier B, Vollmar S, Hoehn M, Van der Linden A, Heneka MT, Jacobs AH. Imaging microglial activation and glucose consumption in a mouse model of Alzheimer's disease. Neurobiol Aging. 2013 Jan; 34(1):351-4.
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    Score: 0.061
  126. Parpura V, Heneka MT, Montana V, Oliet SH, Schousboe A, Haydon PG, Stout RF, Spray DC, Reichenbach A, Pannicke T, Pekny M, Pekna M, Zorec R, Verkhratsky A. Glial cells in (patho)physiology. J Neurochem. 2012 Apr; 121(1):4-27.
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    Score: 0.059
  127. Kummer MP, Hermes M, Delekarte A, Hammerschmidt T, Kumar S, Terwel D, Walter J, Pape HC, K?nig S, Roeber S, Jessen F, Klockgether T, Korte M, Heneka MT. Nitration of tyrosine 10 critically enhances amyloid ? aggregation and plaque formation. Neuron. 2011 Sep 08; 71(5):833-44.
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    Score: 0.058
  128. Mildner A, Schlevogt B, Kierdorf K, B?ttcher C, Erny D, Kummer MP, Quinn M, Br?ck W, Bechmann I, Heneka MT, Priller J, Prinz M. Distinct and non-redundant roles of microglia and myeloid subsets in mouse models of Alzheimer's disease. J Neurosci. 2011 Aug 03; 31(31):11159-71.
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    Score: 0.057
  129. Mattsson N, Andreasson U, Persson S, Arai H, Batish SD, Bernardini S, Bocchio-Chiavetto L, Blankenstein MA, Carrillo MC, Chalbot S, Coart E, Chiasserini D, Cutler N, Dahlfors G, Duller S, Fagan AM, Forlenza O, Frisoni GB, Galasko D, Galimberti D, Hampel H, Handberg A, Heneka MT, Herskovits AZ, Herukka SK, Holtzman DM, Humpel C, Hyman BT, Iqbal K, Jucker M, Kaeser SA, Kaiser E, Kapaki E, Kidd D, Klivenyi P, Knudsen CS, Kummer MP, Lui J, Llad? A, Lewczuk P, Li QX, Martins R, Masters C, McAuliffe J, Mercken M, Moghekar A, Molinuevo JL, Montine TJ, Nowatzke W, O'Brien R, Otto M, Paraskevas GP, Parnetti L, Petersen RC, Prvulovic D, de Reus HP, Rissman RA, Scarpini E, Stefani A, Soininen H, Schr?der J, Shaw LM, Skinningsrud A, Skrogstad B, Spreer A, Talib L, Teunissen C, Trojanowski JQ, Tumani H, Umek RM, Van Broeck B, Vanderstichele H, Vecsei L, Verbeek MM, Windisch M, Zhang J, Zetterberg H, Blennow K. The Alzheimer's Association external quality control program for cerebrospinal fluid biomarkers. Alzheimers Dement. 2011 Jul; 7(4):386-395.e6.
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    Score: 0.057
  130. Kumar S, Rezaei-Ghaleh N, Terwel D, Thal DR, Richard M, Hoch M, Mc Donald JM, W?llner U, Glebov K, Heneka MT, Walsh DM, Zweckstetter M, Walter J. Extracellular phosphorylation of the amyloid ?-peptide promotes formation of toxic aggregates during the pathogenesis of Alzheimer's disease. EMBO J. 2011 Jun 01; 30(11):2255-65.
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    Score: 0.056
  131. Perez Nievas BG, Hammerschmidt T, Kummer MP, Terwel D, Leza JC, Heneka MT. Restraint stress increases neuroinflammation independently of amyloid ? levels in amyloid precursor protein/PS1 transgenic mice. J Neurochem. 2011 Jan; 116(1):43-52.
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    Score: 0.055
  132. Heneka MT, Rodr?guez JJ, Verkhratsky A. Neuroglia in neurodegeneration. Brain Res Rev. 2010 May; 63(1-2):189-211.
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    Score: 0.051
  133. Jiang Q, Heneka M, Landreth GE. The role of peroxisome proliferator-activated receptor-gamma (PPARgamma) in Alzheimer's disease: therapeutic implications. CNS Drugs. 2008; 22(1):1-14.
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    Score: 0.045
  134. Kalinin S, Gavrilyuk V, Polak PE, Vasser R, Zhao J, Heneka MT, Feinstein DL. Noradrenaline deficiency in brain increases beta-amyloid plaque burden in an animal model of Alzheimer's disease. Neurobiol Aging. 2007 Aug; 28(8):1206-14.
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    Score: 0.040
  135. Sastre M, Dewachter I, Rossner S, Bogdanovic N, Rosen E, Borghgraef P, Evert BO, Dumitrescu-Ozimek L, Thal DR, Landreth G, Walter J, Klockgether T, van Leuven F, Heneka MT. Nonsteroidal anti-inflammatory drugs repress beta-secretase gene promoter activity by the activation of PPARgamma. Proc Natl Acad Sci U S A. 2006 Jan 10; 103(2):443-8.
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    Score: 0.039
  136. Klotz L, Sastre M, Kreutz A, Gavrilyuk V, Klockgether T, Feinstein DL, Heneka MT. Noradrenaline induces expression of peroxisome proliferator activated receptor gamma (PPARgamma) in murine primary astrocytes and neurons. J Neurochem. 2003 Aug; 86(4):907-16.
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    Score: 0.033
  137. Labzin LI, Heneka MT, Latz E. Innate Immunity and Neurodegeneration. Annu Rev Med. 2018 01 29; 69:437-449.
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    Score: 0.022
  138. M?ller S, Preische O, G?pfert JC, Ya?ez VAC, Joos TO, Boecker H, D?zel E, Falkai P, Priller J, Buerger K, Catak C, Janowitz D, Heneka MT, Brosseron F, Nestor P, Peters O, Menne F, Schipke CG, Schneider A, Spottke A, Flie?bach K, Kilimann I, Teipel S, Wagner M, Wiltfang J, Jessen F, Laske C. Tau plasma levels in subjective cognitive decline: Results from the DELCODE study. Sci Rep. 2017 08 25; 7(1):9529.
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    Score: 0.022
  139. Willem M, Tahirovic S, Busche MA, Ovsepian SV, Chafai M, Kootar S, Hornburg D, Evans LD, Moore S, Daria A, Hampel H, M?ller V, Giudici C, Nuscher B, Wenninger-Weinzierl A, Kremmer E, Heneka MT, Thal DR, Giedraitis V, Lannfelt L, M?ller U, Livesey FJ, Meissner F, Herms J, Konnerth A, Marie H, Haass C. ?-Secretase processing of APP inhibits neuronal activity in the hippocampus. Nature. 2015 Oct 15; 526(7573):443-7.
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    Score: 0.019
  140. Kleinberger G, Yamanishi Y, Su?rez-Calvet M, Czirr E, Lohmann E, Cuyvers E, Struyfs H, Pettkus N, Wenninger-Weinzierl A, Mazaheri F, Tahirovic S, Lle? A, Alcolea D, Fortea J, Willem M, Lammich S, Molinuevo JL, S?nchez-Valle R, Antonell A, Ramirez A, Heneka MT, Sleegers K, van der Zee J, Martin JJ, Engelborghs S, Demirtas-Tatlidede A, Zetterberg H, Van Broeckhoven C, Gurvit H, Wyss-Coray T, Hardy J, Colonna M, Haass C. TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis. Sci Transl Med. 2014 Jul 02; 6(243):243ra86.
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    Score: 0.018
  141. Thelen M, Razquin C, Hern?ndez I, Gorostidi A, S?nchez-Valle R, Ortega-Cubero S, Wolfsgruber S, Drichel D, Fliessbach K, Duenkel T, Damian M, Heilmann S, Slotosch A, Lennarz M, Seijo-Mart?nez M, Rene R, Kornhuber J, Peters O, Luckhaus C, Jahn H, H?ll M, R?ther E, Wiltfang J, Lorenzo E, Gascon J, Lle? A, Llad? A, Campdelacreu J, Moreno F, Ahmadzadehfar H, Fortea J, Indakoetxea B, Heneka MT, Wetter A, Pastor MA, Riverol M, Becker T, Fr?lich L, T?rraga L, Boada M, Wagner M, Jessen F, Maier W, Clarim?n J, L?pez de Munain A, Ruiz A, Pastor P, Ramirez A. Investigation of the role of rare TREM2 variants in frontotemporal dementia subtypes. Neurobiol Aging. 2014 Nov; 35(11):2657.e13-2657.e19.
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    Score: 0.018
  142. van der Zee J, Gijselinck I, Dillen L, Van Langenhove T, Theuns J, Engelborghs S, Philtjens S, Vandenbulcke M, Sleegers K, Sieben A, B?umer V, Maes G, Corsmit E, Borroni B, Padovani A, Archetti S, Perneczky R, Diehl-Schmid J, de Mendon?a A, Miltenberger-Miltenyi G, Pereira S, Pimentel J, Nacmias B, Bagnoli S, Sorbi S, Graff C, Chiang HH, Westerlund M, Sanchez-Valle R, Llado A, Gelpi E, Santana I, Almeida MR, Santiago B, Frisoni G, Zanetti O, Bonvicini C, Synofzik M, Maetzler W, Vom Hagen JM, Sch?ls L, Heneka MT, Jessen F, Matej R, Parobkova E, Kovacs GG, Str?bel T, Sarafov S, Tournev I, Jordanova A, Danek A, Arzberger T, Fabrizi GM, Testi S, Salmon E, Santens P, Martin JJ, Cras P, Vandenberghe R, De Deyn PP, Cruts M, Van Broeckhoven C, van der Zee J, Gijselinck I, Dillen L, Van Langenhove T, Theuns J, Philtjens S, Sleegers K, B?umer V, Maes G, Corsmit E, Cruts M, Van Broeckhoven C, van der Zee J, Gijselinck I, Dillen L, Van Langenhove T, Philtjens S, Theuns J, Sleegers K, B?umer V, Maes G, Cruts M, Van Broeckhoven C, Engelborghs S, De Deyn PP, Cras P, Engelborghs S, De Deyn PP, Vandenbulcke M, Vandenbulcke M, Borroni B, Padovani A, Archetti S, Perneczky R, Diehl-Schmid J, Synofzik M, Maetzler W, M?ller Vom Hagen J, Sch?ls L, Synofzik M, Maetzler W, M?ller Vom Hagen J, Sch?ls L, Heneka MT, Jessen F, Ramirez A, Kurzwelly D, Sachtleben C, Mairer W, de Mendon?a A, Miltenberger-Miltenyi G, Pereira S, Firmo C, Pimentel J, Sanchez-Valle R, Llado A, Antonell A, Molinuevo J, Gelpi E, Graff C, Chiang HH, Westerlund M, Graff C, Kinhult St?hlbom A, Thonberg H, Nennesmo I, B?rjesson-Hanson A, Nacmias B, Bagnoli S, Sorbi S, Bessi V, Piaceri I, Santana I, Santiago B, Santana I, Helena Ribeiro M, Ros?rio Almeida M, Oliveira C, Massano J, Garret C, Pires P, Frisoni G, Zanetti O, Bonvicini C, Sarafov S, Tournev I, Jordanova A, Tournev I, Kovacs GG, Str?bel T, Heneka MT, Jessen F, Ramirez A, Kurzwelly D, Sachtleben C, Mairer W, Jessen F, Matej R, Parobkova E, Danel A, Arzberger T, Maria Fabrizi G, Testi S, Ferrari S, Cavallaro T, Salmon E, Santens P, Cras P. A pan-European study of the C9orf72 repeat associated with FTLD: geographic prevalence, genomic instability, and intermediate repeats. Hum Mutat. 2013 Feb; 34(2):363-73.
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    Score: 0.016
  143. Liu S, Liu Y, Hao W, Wolf L, Kiliaan AJ, Penke B, R?be CE, Walter J, Heneka MT, Hartmann T, Menger MD, Fassbender K. TLR2 is a primary receptor for Alzheimer's amyloid ? peptide to trigger neuroinflammatory activation. J Immunol. 2012 Feb 01; 188(3):1098-107.
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    Score: 0.015
  144. Tamboli IY, Barth E, Christian L, Siepmann M, Kumar S, Singh S, Tolksdorf K, Heneka MT, L?tjohann D, Wunderlich P, Walter J. Statins promote the degradation of extracellular amyloid {beta}-peptide by microglia via stimulation of exosome-associated insulin-degrading enzyme (IDE) secretion. J Biol Chem. 2010 Nov 26; 285(48):37405-14.
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    Score: 0.014
  145. Tamboli IY, Prager K, Barth E, Heneka M, Sandhoff K, Walter J. Inhibition of glycosphingolipid biosynthesis reduces secretion of the beta-amyloid precursor protein and amyloid beta-peptide. J Biol Chem. 2005 Jul 29; 280(30):28110-7.
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    Score: 0.009
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Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.