Barbara Osborne to Signal Transduction
This is a "connection" page, showing publications Barbara Osborne has written about Signal Transduction.
Connection Strength
2.675
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Mitra A, Shanthalingam S, Sherman HL, Singh K, Canakci M, Torres JA, Lawlor R, Ran Y, Golde TE, Miele L, Thayumanavan S, Minter LM, Osborne BA. CD28 Signaling Drives Notch Ligand Expression on CD4 T Cells. Front Immunol. 2020; 11:735.
Score: 0.340
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Vijayaraghavan J, Osborne BA. Notch and T Cell Function - A Complex Tale. Adv Exp Med Biol. 2018; 1066:339-354.
Score: 0.289
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Minter LM, Osborne BA. Notch and the survival of regulatory T cells: location is everything! Sci Signal. 2012 Jul 24; 5(234):pe31.
Score: 0.198
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Minter LM, Osborne BA. Canonical and non-canonical Notch signaling in CD4? T cells. Curr Top Microbiol Immunol. 2012; 360:99-114.
Score: 0.190
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Keerthivasan S, Suleiman R, Lawlor R, Roderick J, Bates T, Minter L, Anguita J, Juncadella I, Nickoloff BJ, Le Poole IC, Miele L, Osborne BA. Notch signaling regulates mouse and human Th17 differentiation. J Immunol. 2011 Jul 15; 187(2):692-701.
Score: 0.183
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Palaga T, Buranaruk C, Rengpipat S, Fauq AH, Golde TE, Kaufmann SH, Osborne BA. Notch signaling is activated by TLR stimulation and regulates macrophage functions. Eur J Immunol. 2008 Jan; 38(1):174-83.
Score: 0.144
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Osborne BA, Minter LM. Notch signalling during peripheral T-cell activation and differentiation. Nat Rev Immunol. 2007 Jan; 7(1):64-75.
Score: 0.134
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Palaga T, Miele L, Golde TE, Osborne BA. TCR-mediated Notch signaling regulates proliferation and IFN-gamma production in peripheral T cells. J Immunol. 2003 Sep 15; 171(6):3019-24.
Score: 0.107
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Morgan G, Smith S, Pak J, Marshak-Rothstein A, Fissore R, Osborne B. Characterization of a mutant T-cell hybridoma line with defects in the TCR-mediated apoptotic pathway. Cell Death Differ. 1999 Jan; 6(1):36-47.
Score: 0.077
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Wongchana W, Kongkavitoon P, Tangtanatakul P, Sittplangkoon C, Butta P, Chawalitpong S, Pattarakankul T, Osborne BA, Palaga T. Notch signaling regulates the responses of lipopolysaccharide-stimulated macrophages in the presence of immune complexes. PLoS One. 2018; 13(6):e0198609.
Score: 0.074
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Hossain F, Majumder S, Ucar DA, Rodriguez PC, Golde TE, Minter LM, Osborne BA, Miele L. Notch Signaling in Myeloid Cells as a Regulator of Tumor Immune Responses. Front Immunol. 2018; 9:1288.
Score: 0.074
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Wang Y, Yu S, Huang D, Cui M, Hu H, Zhang L, Wang W, Parameswaran N, Jackson M, Osborne B, Bedogni B, Li C, Sy MS, Xin W, Zhou L. Cellular Prion Protein Mediates Pancreatic Cancer Cell Survival and Invasion through Association with and Enhanced Signaling of Notch1. Am J Pathol. 2016 11; 186(11):2945-2956.
Score: 0.066
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Yun J, Espinoza I, Pannuti A, Romero D, Martinez L, Caskey M, Stanculescu A, Bocchetta M, Rizzo P, Band V, Band H, Kim HM, Park SK, Kang KW, Avantaggiati ML, Gomez CR, Golde T, Osborne B, Miele L. p53 Modulates Notch Signaling in MCF-7 Breast Cancer Cells by Associating With the Notch Transcriptional Complex Via MAML1. J Cell Physiol. 2015 Dec; 230(12):3115-27.
Score: 0.062
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Sangphech N, Osborne BA, Palaga T. Notch signaling regulates the phosphorylation of Akt and survival of lipopolysaccharide-activated macrophages via regulator of G protein signaling 19 (RGS19). Immunobiology. 2014 Sep; 219(9):653-60.
Score: 0.056
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Liu ZG, Smith SW, McLaughlin KA, Schwartz LM, Osborne BA. Apoptotic signals delivered through the T-cell receptor of a T-cell hybrid require the immediate-early gene nur77. Nature. 1994 Jan 20; 367(6460):281-4.
Score: 0.055
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Yan H, Blackburn AC, McLary SC, Tao L, Roberts AL, Xavier EA, Dickinson ES, Seo JH, Arenas RB, Otis CN, Cao QJ, Lawlor RG, Osborne BA, Kittrell FS, Medina D, Jerry DJ. Pathways contributing to development of spontaneous mammary tumors in BALB/c-Trp53+/- mice. Am J Pathol. 2010 Mar; 176(3):1421-32.
Score: 0.042
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Cho OH, Shin HM, Miele L, Golde TE, Fauq A, Minter LM, Osborne BA. Notch regulates cytolytic effector function in CD8+ T cells. J Immunol. 2009 Mar 15; 182(6):3380-9.
Score: 0.039
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Rizzo P, Osipo C, Pannuti A, Golde T, Osborne B, Miele L. Targeting Notch signaling cross-talk with estrogen receptor and ErbB-2 in breast cancer. Adv Enzyme Regul. 2009; 49(1):134-41.
Score: 0.039
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Joshi I, Minter LM, Telfer J, Demarest RM, Capobianco AJ, Aster JC, Sicinski P, Fauq A, Golde TE, Osborne BA. Notch signaling mediates G1/S cell-cycle progression in T cells via cyclin D3 and its dependent kinases. Blood. 2009 Feb 19; 113(8):1689-98.
Score: 0.038
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Samon JB, Champhekar A, Minter LM, Telfer JC, Miele L, Fauq A, Das P, Golde TE, Osborne BA. Notch1 and TGFbeta1 cooperatively regulate Foxp3 expression and the maintenance of peripheral regulatory T cells. Blood. 2008 Sep 01; 112(5):1813-21.
Score: 0.037
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Miele L, Golde T, Osborne B. Notch signaling in cancer. Curr Mol Med. 2006 Dec; 6(8):905-18.
Score: 0.033
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Shin HM, Minter LM, Cho OH, Gottipati S, Fauq AH, Golde TE, Sonenshein GE, Osborne BA. Notch1 augments NF-kappaB activity by facilitating its nuclear retention. EMBO J. 2006 Jan 11; 25(1):129-38.
Score: 0.031
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Cheng P, Nefedova Y, Miele L, Osborne BA, Gabrilovich D. Notch signaling is necessary but not sufficient for differentiation of dendritic cells. Blood. 2003 Dec 01; 102(12):3980-8.
Score: 0.027
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Weijzen S, Rizzo P, Braid M, Vaishnav R, Jonkheer SM, Zlobin A, Osborne BA, Gottipati S, Aster JC, Hahn WC, Rudolf M, Siziopikou K, Kast WM, Miele L. Activation of Notch-1 signaling maintains the neoplastic phenotype in human Ras-transformed cells. Nat Med. 2002 Sep; 8(9):979-86.
Score: 0.025
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Majumder S, Crabtree JS, Golde TE, Minter LM, Osborne BA, Miele L. Targeting Notch in oncology: the path forward. Nat Rev Drug Discov. 2021 02; 20(2):125-144.
Score: 0.022
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Ozay EI, Shanthalingam S, Torres JA, Osborne BA, Tew GN, Minter LM. Protein Kinase C Theta Modulates PCMT1 through hnRNPL to Regulate FOXP3 Stability in Regulatory T Cells. Mol Ther. 2020 10 07; 28(10):2220-2236.
Score: 0.021
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Ozay EI, Shanthalingam S, Sherman HL, Torres JA, Osborne BA, Tew GN, Minter LM. Cell-Penetrating Anti-Protein Kinase C Theta Antibodies Act Intracellularly to Generate Stable, Highly Suppressive Regulatory T Cells. Mol Ther. 2020 09 02; 28(9):1987-2006.
Score: 0.021
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Lessard CB, Rodriguez E, Ladd TB, Minter LM, Osborne BA, Miele L, Golde TE, Ran Y. ?-Secretase modulators exhibit selectivity for modulation of APP cleavage but inverse ?-secretase modulators do not. Alzheimers Res Ther. 2020 05 19; 12(1):61.
Score: 0.021
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Miele L, Osborne B. Arbiter of differentiation and death: Notch signaling meets apoptosis. J Cell Physiol. 1999 Dec; 181(3):393-409.
Score: 0.021
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Osborne B, Miele L. Notch and the immune system. Immunity. 1999 Dec; 11(6):653-63.
Score: 0.021
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Amsen D, Revilla Calvo C, Osborne BA, Kruisbeek AM. Costimulatory signals are required for induction of transcription factor Nur77 during negative selection of CD4(+)CD8(+) thymocytes. Proc Natl Acad Sci U S A. 1999 Jan 19; 96(2):622-7.
Score: 0.019
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Chandiran K, Lawlor R, Pannuti A, Perez GG, Srinivasan J, Golde TE, Miele L, Osborne BA, Minter LM. Notch1 primes CD4 T cells for T helper type I differentiation through its early effects on miR-29. Mol Immunol. 2018 07; 99:191-198.
Score: 0.019
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Sierra RA, Trillo-Tinoco J, Mohamed E, Yu L, Achyut BR, Arbab A, Bradford JW, Osborne BA, Miele L, Rodriguez PC. Anti-Jagged Immunotherapy Inhibits MDSCs and Overcomes Tumor-Induced Tolerance. Cancer Res. 2017 10 15; 77(20):5628-5638.
Score: 0.018
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Jehn BM, Osborne BA. Gene regulation associated with apoptosis. Crit Rev Eukaryot Gene Expr. 1997; 7(1-2):179-93.
Score: 0.017
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Ozay EI, Gonzalez-Perez G, Torres JA, Vijayaraghavan J, Lawlor R, Sherman HL, Garrigan DT, Burnside AS, Osborne BA, Tew GN, Minter LM. Intracellular Delivery of Anti-pPKC? (Thr538) via Protein Transduction Domain Mimics for Immunomodulation. Mol Ther. 2016 Dec; 24(12):2118-2130.
Score: 0.016
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Montgomery MK, Fiveash CE, Braude JP, Osborne B, Brown SH, Mitchell TW, Turner N. Disparate metabolic response to fructose feeding between different mouse strains. Sci Rep. 2015 Dec 22; 5:18474.
Score: 0.016
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Wongchana W, Lawlor RG, Osborne BA, Palaga T. Impact of Notch1 Deletion in Macrophages on Proinflammatory Cytokine Production and the Outcome of Experimental Autoimmune Encephalomyelitis. J Immunol. 2015 Dec 01; 195(11):5337-46.
Score: 0.016
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Schwartz LM, Osborne BA. Programmed cell death, apoptosis and killer genes. Immunol Today. 1993 Dec; 14(12):582-90.
Score: 0.014
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Golde TE, Koo EH, Felsenstein KM, Osborne BA, Miele L. ?-Secretase inhibitors and modulators. Biochim Biophys Acta. 2013 Dec; 1828(12):2898-907.
Score: 0.013
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Pannuti A, Foreman K, Rizzo P, Osipo C, Golde T, Osborne B, Miele L. Targeting Notch to target cancer stem cells. Clin Cancer Res. 2010 Jun 15; 16(12):3141-52.
Score: 0.011
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Rizzo P, Osipo C, Foreman K, Golde T, Osborne B, Miele L. Rational targeting of Notch signaling in cancer. Oncogene. 2008 Sep 01; 27(38):5124-31.
Score: 0.009
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Osipo C, Golde TE, Osborne BA, Miele LA. Off the beaten pathway: the complex cross talk between Notch and NF-kappaB. Lab Invest. 2008 Jan; 88(1):11-7.
Score: 0.009
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Nickoloff BJ, Osborne BA, Miele L. Notch signaling as a therapeutic target in cancer: a new approach to the development of cell fate modifying agents. Oncogene. 2003 Sep 29; 22(42):6598-608.
Score: 0.007
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Punt JA, Osborne BA, Takahama Y, Sharrow SO, Singer A. Negative selection of CD4+CD8+ thymocytes by T cell receptor-induced apoptosis requires a costimulatory signal that can be provided by CD28. J Exp Med. 1994 Feb 01; 179(2):709-13.
Score: 0.003