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Dale Greiner to Mice, Inbred NOD

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This is a "connection" page, showing publications Dale Greiner has written about Mice, Inbred NOD.
Dale Greiner
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4.086
Mice, Inbred NOD
  1. King M, Pearson T, Shultz LD, Leif J, Bottino R, Trucco M, Atkinson M, Wasserfall C, Herold K, Mordes JP, Rossini AA, Greiner DL. Development of new-generation HU-PBMC-NOD/SCID mice to study human islet alloreactivity. Ann N Y Acad Sci. 2007 Apr; 1103:90-3.
    View in: PubMed
    Score: 0.252
  2. Amdare NP, Shultz LD, Greiner DL, DiLorenzo TP. Human insulin as both antigen and protector in type 1 diabetes. Eur J Immunol. 2024 Sep; 54(9):e2350949.
    View in: PubMed
    Score: 0.207
  3. Shultz LD, Banuelos S, Lyons B, Samuels R, Burzenski L, Gott B, Lang P, Leif J, Appel M, Rossini A, Greiner DL. NOD/LtSz-Rag1nullPfpnull mice: a new model system with increased levels of human peripheral leukocyte and hematopoietic stem-cell engraftment. Transplantation. 2003 Oct 15; 76(7):1036-42.
    View in: PubMed
    Score: 0.199
  4. Pearson T, Markees TG, Serreze DV, Pierce MA, Wicker LS, Peterson LB, Shultz LD, Mordes JP, Rossini AA, Greiner DL. Genetic separation of the transplantation tolerance and autoimmune phenotypes in NOD mice. Rev Endocr Metab Disord. 2003 Sep; 4(3):255-61.
    View in: PubMed
    Score: 0.197
  5. Friedline RH, Ko HJ, Jung DY, Lee Y, Bortell R, Dagdeviren S, Patel PR, Hu X, Inashima K, Kearns C, Tsitsilianos N, Shafiq U, Shultz LD, Lee KW, Greiner DL, Kim JK. Genetic ablation of lymphocytes and cytokine signaling in nonobese diabetic mice prevents diet-induced obesity and insulin resistance. FASEB J. 2016 Mar; 30(3):1328-38.
    View in: PubMed
    Score: 0.115
  6. Rossini AA, Handler ES, Mordes JP, Greiner DL. Human autoimmune diabetes mellitus: lessons from BB rats and NOD mice--Caveat emptor. Clin Immunol Immunopathol. 1995 Jan; 74(1):2-9.
    View in: PubMed
    Score: 0.108
  7. Shultz LD, Schweitzer PA, Christianson SW, Gott B, Schweitzer IB, Tennent B, McKenna S, Mobraaten L, Rajan TV, Greiner DL, et al. Multiple defects in innate and adaptive immunologic function in NOD/LtSz-scid mice. J Immunol. 1995 Jan 01; 154(1):180-91.
    View in: PubMed
    Score: 0.108
  8. Brehm MA, Powers AC, Shultz LD, Greiner DL. Advancing animal models of human type 1 diabetes by engraftment of functional human tissues in immunodeficient mice. Cold Spring Harb Perspect Med. 2012 May; 2(5):a007757.
    View in: PubMed
    Score: 0.090
  9. Brehm MA, Racki WJ, Leif J, Burzenski L, Hosur V, Wetmore A, Gott B, Herlihy M, Ignotz R, Dunn R, Shultz LD, Greiner DL. Engraftment of human HSCs in nonirradiated newborn NOD-scid IL2r? null mice is enhanced by transgenic expression of membrane-bound human SCF. Blood. 2012 Mar 22; 119(12):2778-88.
    View in: PubMed
    Score: 0.088
  10. Shultz LD, Brehm MA, Bavari S, Greiner DL. Humanized mice as a preclinical tool for infectious disease and biomedical research. Ann N Y Acad Sci. 2011 Dec; 1245:50-4.
    View in: PubMed
    Score: 0.087
  11. Greiner DL, Brehm MA, Hosur V, Harlan DM, Powers AC, Shultz LD. Humanized mice for the study of type 1 and type 2 diabetes. Ann N Y Acad Sci. 2011 Dec; 1245:55-8.
    View in: PubMed
    Score: 0.087
  12. Liu G, Dou S, Cheng D, Leif J, Rusckowski M, Streeter PR, Shultz LD, Hnatowich DJ, Greiner DL. Human islet cell MORF/cMORF pretargeting in a xenogeneic murine transplant model. Mol Pharm. 2011 Jun 06; 8(3):767-73.
    View in: PubMed
    Score: 0.084
  13. Racki WJ, Covassin L, Brehm M, Pino S, Ignotz R, Dunn R, Laning J, Graves SK, Rossini AA, Shultz LD, Greiner DL. NOD-scid IL2rgamma(null) mouse model of human skin transplantation and allograft rejection. Transplantation. 2010 Mar 15; 89(5):527-36.
    View in: PubMed
    Score: 0.078
  14. Brehm MA, Cuthbert A, Yang C, Miller DM, DiIorio P, Laning J, Burzenski L, Gott B, Foreman O, Kavirayani A, Herlihy M, Rossini AA, Shultz LD, Greiner DL. Parameters for establishing humanized mouse models to study human immunity: analysis of human hematopoietic stem cell engraftment in three immunodeficient strains of mice bearing the IL2rgamma(null) mutation. Clin Immunol. 2010 Apr; 135(1):84-98.
    View in: PubMed
    Score: 0.077
  15. King MA, Covassin L, Brehm MA, Racki W, Pearson T, Leif J, Laning J, Fodor W, Foreman O, Burzenski L, Chase TH, Gott B, Rossini AA, Bortell R, Shultz LD, Greiner DL. Human peripheral blood leucocyte non-obese diabetic-severe combined immunodeficiency interleukin-2 receptor gamma chain gene mouse model of xenogeneic graft-versus-host-like disease and the role of host major histocompatibility complex. Clin Exp Immunol. 2009 Jul; 157(1):104-18.
    View in: PubMed
    Score: 0.074
  16. Mangada J, Pearson T, Brehm MA, Wicker LS, Peterson LB, Shultz LD, Serreze DV, Rossini AA, Greiner DL. Idd loci synergize to prolong islet allograft survival induced by costimulation blockade in NOD mice. Diabetes. 2009 Jan; 58(1):165-73.
    View in: PubMed
    Score: 0.071
  17. Pearson T, Shultz LD, Miller D, King M, Laning J, Fodor W, Cuthbert A, Burzenski L, Gott B, Lyons B, Foreman O, Rossini AA, Greiner DL. Non-obese diabetic-recombination activating gene-1 (NOD-Rag1 null) interleukin (IL)-2 receptor common gamma chain (IL2r gamma null) null mice: a radioresistant model for human lymphohaematopoietic engraftment. Clin Exp Immunol. 2008 Nov; 154(2):270-84.
    View in: PubMed
    Score: 0.070
  18. Giassi LJ, Pearson T, Shultz LD, Laning J, Biber K, Kraus M, Woda BA, Schmidt MR, Woodland RT, Rossini AA, Greiner DL. Expanded CD34+ human umbilical cord blood cells generate multiple lymphohematopoietic lineages in NOD-scid IL2rgamma(null) mice. Exp Biol Med (Maywood). 2008 Aug; 233(8):997-1012.
    View in: PubMed
    Score: 0.069
  19. Pearson T, Shultz LD, Lief J, Burzenski L, Gott B, Chase T, Foreman O, Rossini AA, Bottino R, Trucco M, Greiner DL. A new immunodeficient hyperglycaemic mouse model based on the Ins2Akita mutation for analyses of human islet and beta stem and progenitor cell function. Diabetologia. 2008 Aug; 51(8):1449-56.
    View in: PubMed
    Score: 0.069
  20. King M, Pearson T, Shultz LD, Leif J, Bottino R, Trucco M, Atkinson MA, Wasserfall C, Herold KC, Woodland RT, Schmidt MR, Woda BA, Thompson MJ, Rossini AA, Greiner DL. A new Hu-PBL model for the study of human islet alloreactivity based on NOD-scid mice bearing a targeted mutation in the IL-2 receptor gamma chain gene. Clin Immunol. 2008 Mar; 126(3):303-14.
    View in: PubMed
    Score: 0.066
  21. Shultz LD, Pearson T, King M, Giassi L, Carney L, Gott B, Lyons B, Rossini AA, Greiner DL. Humanized NOD/LtSz-scid IL2 receptor common gamma chain knockout mice in diabetes research. Ann N Y Acad Sci. 2007 Apr; 1103:77-89.
    View in: PubMed
    Score: 0.063
  22. Serreze DV, Osborne MA, Chen YG, Chapman HD, Pearson T, Brehm MA, Greiner DL. Partial versus full allogeneic hemopoietic chimerization is a preferential means to inhibit type 1 diabetes as the latter induces generalized immunosuppression. J Immunol. 2006 Nov 15; 177(10):6675-84.
    View in: PubMed
    Score: 0.062
  23. Pearson T, Weiser P, Markees TG, Serreze DV, Wicker LS, Peterson LB, Cumisky AM, Shultz LD, Mordes JP, Rossini AA, Greiner DL. Islet allograft survival induced by costimulation blockade in NOD mice is controlled by allelic variants of Idd3. Diabetes. 2004 Aug; 53(8):1972-8.
    View in: PubMed
    Score: 0.053
  24. Pearson T, Markees TG, Serreze DV, Pierce MA, Wicker LS, Peterson LB, Shultz LD, Mordes JP, Rossini AA, Greiner DL. Islet cell autoimmunity and transplantation tolerance: two distinct mechanisms? Ann N Y Acad Sci. 2003 Nov; 1005:148-56.
    View in: PubMed
    Score: 0.050
  25. Pearson T, Markees TG, Serreze DV, Pierce MA, Marron MP, Wicker LS, Peterson LB, Shultz LD, Mordes JP, Rossini AA, Greiner DL. Genetic disassociation of autoimmunity and resistance to costimulation blockade-induced transplantation tolerance in nonobese diabetic mice. J Immunol. 2003 Jul 01; 171(1):185-95.
    View in: PubMed
    Score: 0.049
  26. Shultz LD, Banuelos SJ, Leif J, Appel MC, Cunningham M, Ballen K, Burzenski L, Greiner DL. Regulation of human short-term repopulating cell (STRC) engraftment in NOD/SCID mice by host CD122+ cells. Exp Hematol. 2003 Jun; 31(6):551-8.
    View in: PubMed
    Score: 0.048
  27. Yang J, Jiao J, Draheim KM, Yang G, Yang H, Yao LC, Shultz LD, Greiner DL, Rajagopal D, Vessillier S, Maier CC, Mohanan S, Cai D, Cheng M, Brehm MA, Keck JG. Simultaneous evaluation of treatment efficacy and toxicity for bispecific T-cell engager therapeutics in a humanized mouse model. FASEB J. 2023 06; 37(6):e22995.
    View in: PubMed
    Score: 0.048
  28. Aryee KE, Shultz LD, Burzenski LM, Greiner DL, Brehm MA. NOD-scid IL2r?null mice lacking TLR4 support human immune system development and the study of human-specific innate immunity. J Leukoc Biol. 2023 05 02; 113(5):418-433.
    View in: PubMed
    Score: 0.048
  29. Stadinski BD, Cleveland SB, Brehm MA, Greiner DL, Huseby PG, Huseby ES. I-Ag7 ?56/57 polymorphisms regulate non-cognate negative selection to CD4+ T cell orchestrators of type 1 diabetes. Nat Immunol. 2023 04; 24(4):652-663.
    View in: PubMed
    Score: 0.048
  30. Pearson T, Markees TG, Wicker LS, Serreze DV, Peterson LB, Mordes JP, Rossini AA, Greiner DL. NOD congenic mice genetically protected from autoimmune diabetes remain resistant to transplantation tolerance induction. Diabetes. 2003 Feb; 52(2):321-6.
    View in: PubMed
    Score: 0.047
  31. Aryee KE, Burzenski LM, Yao LC, Keck JG, Greiner DL, Shultz LD, Brehm MA. Enhanced development of functional human NK cells in NOD-scid-IL2rgnull mice expressing human IL15. FASEB J. 2022 09; 36(9):e22476.
    View in: PubMed
    Score: 0.046
  32. Ye C, Yang H, Cheng M, Shultz LD, Greiner DL, Brehm MA, Keck JG. A rapid, sensitive, and reproducible in vivo PBMC humanized murine model for determining therapeutic-related cytokine release syndrome. FASEB J. 2020 09; 34(9):12963-12975.
    View in: PubMed
    Score: 0.040
  33. Dai C, Walker JT, Shostak A, Bouchi Y, Poffenberger G, Hart NJ, Jacobson DA, Calcutt MW, Bottino R, Greiner DL, Shultz LD, McGuinness OP, Dean ED, Powers AC. Dapagliflozin Does Not Directly Affect Human a or ? Cells. Endocrinology. 2020 08 01; 161(8).
    View in: PubMed
    Score: 0.040
  34. Wagar EJ, Cromwell MA, Shultz LD, Woda BA, Sullivan JL, Hesselton RM, Greiner DL. Regulation of human cell engraftment and development of EBV-related lymphoproliferative disorders in Hu-PBL-scid mice. J Immunol. 2000 Jul 01; 165(1):518-27.
    View in: PubMed
    Score: 0.040
  35. Seung E, Iwakoshi N, Woda BA, Markees TG, Mordes JP, Rossini AA, Greiner DL. Allogeneic hematopoietic chimerism in mice treated with sublethal myeloablation and anti-CD154 antibody: absence of graft-versus-host disease, induction of skin allograft tolerance, and prevention of recurrent autoimmunity in islet-allografted NOD/Lt mice. Blood. 2000 Mar 15; 95(6):2175-82.
    View in: PubMed
    Score: 0.039
  36. Shultz LD, Lang PA, Christianson SW, Gott B, Lyons B, Umeda S, Leiter E, Hesselton R, Wagar EJ, Leif JH, Kollet O, Lapidot T, Greiner DL. NOD/LtSz-Rag1null mice: an immunodeficient and radioresistant model for engraftment of human hematolymphoid cells, HIV infection, and adoptive transfer of NOD mouse diabetogenic T cells. J Immunol. 2000 Mar 01; 164(5):2496-507.
    View in: PubMed
    Score: 0.039
  37. Karlinsey JE, Stepien TA, Mayho M, Singletary LA, Bingham-Ramos LK, Brehm MA, Greiner DL, Shultz LD, Gallagher LA, Bawn M, Kingsley RA, Libby SJ, Fang FC. Genome-wide Analysis of Salmonella enterica serovar Typhi in Humanized Mice Reveals Key Virulence Features. Cell Host Microbe. 2019 09 11; 26(3):426-434.e6.
    View in: PubMed
    Score: 0.037
  38. Gawron MA, Duval M, Carbone C, Jaiswal S, Wallace A, Martin JC, Dauphin A, Brehm MA, Greiner DL, Shultz LD, Luban J, Cavacini LA. Human Anti-HIV-1 gp120 Monoclonal Antibodies with Neutralizing Activity Cloned from Humanized Mice Infected with HIV-1. J Immunol. 2019 02 01; 202(3):799-804.
    View in: PubMed
    Score: 0.036
  39. Saunders DC, Brissova M, Phillips N, Shrestha S, Walker JT, Aramandla R, Poffenberger G, Flaherty DK, Weller KP, Pelletier J, Cooper T, Goff MT, Virostko J, Shostak A, Dean ED, Greiner DL, Shultz LD, Prasad N, Levy SE, Carnahan RH, Dai C, S?vigny J, Powers AC. Ectonucleoside Triphosphate Diphosphohydrolase-3 Antibody Targets Adult Human Pancreatic ? Cells for In?Vitro and In?Vivo Analysis. Cell Metab. 2019 03 05; 29(3):745-754.e4.
    View in: PubMed
    Score: 0.035
  40. Brehm MA, Kenney LL, Wiles MV, Low BE, Tisch RM, Burzenski L, Mueller C, Greiner DL, Shultz LD. Lack of acute xenogeneic graft- versus-host disease, but retention of T-cell function following engraftment of human peripheral blood mononuclear cells in NSG mice deficient in MHC class I and II expression. FASEB J. 2019 03; 33(3):3137-3151.
    View in: PubMed
    Score: 0.035
  41. Wang M, Yao LC, Cheng M, Cai D, Martinek J, Pan CX, Shi W, Ma AH, De Vere White RW, Airhart S, Liu ET, Banchereau J, Brehm MA, Greiner DL, Shultz LD, Palucka K, Keck JG. Humanized mice in studying efficacy and mechanisms of PD-1-targeted cancer immunotherapy. FASEB J. 2018 03; 32(3):1537-1549.
    View in: PubMed
    Score: 0.033
  42. Borel F, Tang Q, Gernoux G, Greer C, Wang Z, Barzel A, Kay MA, Shultz LD, Greiner DL, Flotte TR, Brehm MA, Mueller C. Survival Advantage of Both Human Hepatocyte Xenografts and Genome-Edited Hepatocytes for Treatment of a-1 Antitrypsin Deficiency. Mol Ther. 2017 11 01; 25(11):2477-2489.
    View in: PubMed
    Score: 0.033
  43. Dai C, Hang Y, Shostak A, Poffenberger G, Hart N, Prasad N, Phillips N, Levy SE, Greiner DL, Shultz LD, Bottino R, Kim SK, Powers AC. Age-dependent human ? cell proliferation induced by glucagon-like peptide 1 and calcineurin signaling. J Clin Invest. 2017 Oct 02; 127(10):3835-3844.
    View in: PubMed
    Score: 0.033
  44. Lee J, Dykstra B, Spencer JA, Kenney LL, Greiner DL, Shultz LD, Brehm MA, Lin CP, Sackstein R, Rossi DJ. mRNA-mediated glycoengineering ameliorates deficient homing of human stem cell-derived hematopoietic progenitors. J Clin Invest. 2017 Jun 01; 127(6):2433-2437.
    View in: PubMed
    Score: 0.032
  45. Verma MK, Clemens J, Burzenski L, Sampson SB, Brehm MA, Greiner DL, Shultz LD. A novel hemolytic complement-sufficient NSG mouse model supports studies of complement-mediated antitumor activity in vivo. J Immunol Methods. 2017 07; 446:47-53.
    View in: PubMed
    Score: 0.032
  46. Ali R, Babad J, Follenzi A, Gebe JA, Brehm MA, Nepom GT, Shultz LD, Greiner DL, DiLorenzo TP. Genetically modified human CD4(+) T cells can be evaluated in?vivo without lethal graft-versus-host disease. Immunology. 2016 08; 148(4):339-51.
    View in: PubMed
    Score: 0.030
  47. Goel HL, Pursell B, Shultz LD, Greiner DL, Brekken RA, Vander Kooi CW, Mercurio AM. P-Rex1 Promotes Resistance to VEGF/VEGFR-Targeted Therapy in Prostate Cancer. Cell Rep. 2016 Mar 08; 14(9):2193-2208.
    View in: PubMed
    Score: 0.029
  48. Hasgur S, Aryee KE, Shultz LD, Greiner DL, Brehm MA. Generation of Immunodeficient Mice Bearing Human Immune Systems by the Engraftment of Hematopoietic Stem Cells. Methods Mol Biol. 2016; 1438:67-78.
    View in: PubMed
    Score: 0.029
  49. Serreze DV, Leiter EH, Hanson MS, Christianson SW, Shultz LD, Hesselton RM, Greiner DL. Emv30null NOD-scid mice. An improved host for adoptive transfer of autoimmune diabetes and growth of human lymphohematopoietic cells. Diabetes. 1995 Dec; 44(12):1392-8.
    View in: PubMed
    Score: 0.029
  50. Presa M, Chen YG, Grier AE, Leiter EH, Brehm MA, Greiner DL, Shultz LD, Serreze DV. The Presence and Preferential Activation of Regulatory T Cells Diminish Adoptive Transfer of Autoimmune Diabetes by Polyclonal Nonobese Diabetic (NOD) T Cell Effectors into NSG versus NOD-scid Mice. J Immunol. 2015 Oct 01; 195(7):3011-9.
    View in: PubMed
    Score: 0.028
  51. Greiner DL, Shultz LD, Yates J, Appel MC, Perdrizet G, Hesselton RM, Schweitzer I, Beamer WG, Shultz KL, Pelsue SC, et al. Improved engraftment of human spleen cells in NOD/LtSz-scid/scid mice as compared with C.B-17-scid/scid mice. Am J Pathol. 1995 Apr; 146(4):888-902.
    View in: PubMed
    Score: 0.028
  52. Babad J, Mukherjee G, Follenzi A, Ali R, Roep BO, Shultz LD, Santamaria P, Yang OO, Goldstein H, Greiner DL, DiLorenzo TP. Generation of ? cell-specific human cytotoxic T cells by lentiviral transduction and their survival in immunodeficient human leucocyte antigen-transgenic mice. Clin Exp Immunol. 2015 Mar; 179(3):398-413.
    View in: PubMed
    Score: 0.027
  53. Wilson EM, Bial J, Tarlow B, Bial G, Jensen B, Greiner DL, Brehm MA, Grompe M. Extensive double humanization of both liver and hematopoiesis in FRGN mice. Stem Cell Res. 2014 Nov; 13(3 Pt A):404-12.
    View in: PubMed
    Score: 0.026
  54. Purwana I, Zheng J, Li X, Deurloo M, Son DO, Zhang Z, Liang C, Shen E, Tadkase A, Feng ZP, Li Y, Hasilo C, Paraskevas S, Bortell R, Greiner DL, Atkinson M, Prud'homme GJ, Wang Q. GABA promotes human ?-cell proliferation and modulates glucose homeostasis. Diabetes. 2014 Dec; 63(12):4197-205.
    View in: PubMed
    Score: 0.026
  55. Maykel J, Liu JH, Li H, Shultz LD, Greiner DL, Houghton J. NOD-scidIl2rg (tm1Wjl) and NOD-Rag1 (null) Il2rg (tm1Wjl) : a model for stromal cell-tumor cell interaction for human colon cancer. Dig Dis Sci. 2014 Jun; 59(6):1169-79.
    View in: PubMed
    Score: 0.026
  56. Kochupurakkal NM, Kruger AJ, Tripathi S, Zhu B, Adams LT, Rainbow DB, Rossini A, Greiner DL, Sayegh MH, Wicker LS, Guleria I. Blockade of the programmed death-1 (PD1) pathway undermines potent genetic protection from type 1 diabetes. PLoS One. 2014; 9(2):e89561.
    View in: PubMed
    Score: 0.026
  57. Lee J, Brehm MA, Greiner D, Shultz LD, Kornfeld H. Engrafted human cells generate adaptive immune responses to Mycobacterium bovis BCG infection in humanized mice. BMC Immunol. 2013 Dec 07; 14:53.
    View in: PubMed
    Score: 0.025
  58. Jain N, Miu B, Jiang JK, McKinstry KK, Prince A, Swain SL, Greiner DL, Thomas CJ, Sanderson MJ, Berg LJ, Kang J. CD28 and ITK signals regulate autoreactive T cell trafficking. Nat Med. 2013 Dec; 19(12):1632-7.
    View in: PubMed
    Score: 0.025
  59. Wheeler LA, Vrbanac V, Trifonova R, Brehm MA, Gilboa-Geffen A, Tanno S, Greiner DL, Luster AD, Tager AM, Lieberman J. Durable knockdown and protection from HIV transmission in humanized mice treated with gel-formulated CD4 aptamer-siRNA chimeras. Mol Ther. 2013 Jul; 21(7):1378-89.
    View in: PubMed
    Score: 0.024
  60. Goel HL, Pursell B, Chang C, Shaw LM, Mao J, Simin K, Kumar P, Vander Kooi CW, Shultz LD, Greiner DL, Norum JH, Toftgard R, Kuperwasser C, Mercurio AM. GLI1 regulates a novel neuropilin-2/a6?1 integrin based autocrine pathway that contributes to breast cancer initiation. EMBO Mol Med. 2013 Apr; 5(4):488-508.
    View in: PubMed
    Score: 0.024
  61. Unger WW, Pearson T, Abreu JR, Laban S, van der Slik AR, der Kracht SM, Kester MG, Serreze DV, Shultz LD, Griffioen M, Drijfhout JW, Greiner DL, Roep BO. Islet-specific CTL cloned from a type 1 diabetes patient cause beta-cell destruction after engraftment into HLA-A2 transgenic NOD/scid/IL2RG null mice. PLoS One. 2012; 7(11):e49213.
    View in: PubMed
    Score: 0.023
  62. Jaiswal S, Pazoles P, Woda M, Shultz LD, Greiner DL, Brehm MA, Mathew A. Enhanced humoral and HLA-A2-restricted dengue virus-specific T-cell responses in humanized BLT NSG mice. Immunology. 2012 Jul; 136(3):334-43.
    View in: PubMed
    Score: 0.023
  63. Diiorio P, Jurczyk A, Yang C, Racki WJ, Brehm MA, Atkinson MA, Powers AC, Shultz LD, Greiner DL, Bortell R. Hyperglycemia-induced proliferation of adult human beta cells engrafted into spontaneously diabetic immunodeficient NOD-Rag1null IL2r?null Ins2Akita mice. Pancreas. 2011 Oct; 40(7):1147-9.
    View in: PubMed
    Score: 0.022
  64. Niens M, Grier AE, Marron M, Kay TW, Greiner DL, Serreze DV. Prevention of "Humanized" diabetogenic CD8 T-cell responses in HLA-transgenic NOD mice by a multipeptide coupled-cell approach. Diabetes. 2011 Apr; 60(4):1229-36.
    View in: PubMed
    Score: 0.021
  65. Libby SJ, Brehm MA, Greiner DL, Shultz LD, McClelland M, Smith KD, Cookson BT, Karlinsey JE, Kinkel TL, Porwollik S, Canals R, Cummings LA, Fang FC. Humanized nonobese diabetic-scid IL2rgammanull mice are susceptible to lethal Salmonella Typhi infection. Proc Natl Acad Sci U S A. 2010 Aug 31; 107(35):15589-94.
    View in: PubMed
    Score: 0.020
  66. Brehm MA, Bortell R, Diiorio P, Leif J, Laning J, Cuthbert A, Yang C, Herlihy M, Burzenski L, Gott B, Foreman O, Powers AC, Greiner DL, Shultz LD. Human immune system development and rejection of human islet allografts in spontaneously diabetic NOD-Rag1null IL2rgammanull Ins2Akita mice. Diabetes. 2010 Sep; 59(9):2265-70.
    View in: PubMed
    Score: 0.020
  67. Pino S, Brehm MA, Covassin-Barberis L, King M, Gott B, Chase TH, Wagner J, Burzenski L, Foreman O, Greiner DL, Shultz LD. Development of novel major histocompatibility complex class I and class II-deficient NOD-SCID IL2R gamma chain knockout mice for modeling human xenogeneic graft-versus-host disease. Methods Mol Biol. 2010; 602:105-17.
    View in: PubMed
    Score: 0.019
  68. Jaiswal S, Pearson T, Friberg H, Shultz LD, Greiner DL, Rothman AL, Mathew A. Dengue virus infection and virus-specific HLA-A2 restricted immune responses in humanized NOD-scid IL2rgammanull mice. PLoS One. 2009 Oct 05; 4(10):e7251.
    View in: PubMed
    Score: 0.019
  69. Chopra P, Diiorio P, Pino SC, Wilson SB, Phillips NE, Mordes JP, Rossini AA, Greiner DL, Shultz LD, Bortell R. Failure of alpha-galactosylceramide to prevent diabetes in virus-inducible models of type 1 diabetes in the rat. In Vivo. 2009 Mar-Apr; 23(2):195-201.
    View in: PubMed
    Score: 0.018
  70. Schmidt MR, Appel MC, Giassi LJ, Greiner DL, Shultz LD, Woodland RT. Human BLyS facilitates engraftment of human PBL derived B cells in immunodeficient mice. PLoS One. 2008 Sep 11; 3(9):e3192.
    View in: PubMed
    Score: 0.017
  71. Kumar P, Ban HS, Kim SS, Wu H, Pearson T, Greiner DL, Laouar A, Yao J, Haridas V, Habiro K, Yang YG, Jeong JH, Lee KY, Kim YH, Kim SW, Peipp M, Fey GH, Manjunath N, Shultz LD, Lee SK, Shankar P. T cell-specific siRNA delivery suppresses HIV-1 infection in humanized mice. Cell. 2008 Aug 22; 134(4):577-86.
    View in: PubMed
    Score: 0.017
  72. Pearson T, Greiner DL, Shultz LD. Creation of "humanized" mice to study human immunity. Curr Protoc Immunol. 2008 May; Chapter 15:15.21.1-15.21.21.
    View in: PubMed
    Score: 0.017
  73. Pearson T, Greiner DL, Shultz LD. Humanized SCID mouse models for biomedical research. Curr Top Microbiol Immunol. 2008; 324:25-51.
    View in: PubMed
    Score: 0.017
  74. Shultz LD, Lyons BL, Burzenski LM, Gott B, Chen X, Chaleff S, Kotb M, Gillies SD, King M, Mangada J, Greiner DL, Handgretinger R. Human lymphoid and myeloid cell development in NOD/LtSz-scid IL2R gamma null mice engrafted with mobilized human hemopoietic stem cells. J Immunol. 2005 May 15; 174(10):6477-89.
    View in: PubMed
    Score: 0.014
  75. Jaeschke A, Rinc?n M, Doran B, Reilly J, Neuberg D, Greiner DL, Shultz LD, Rossini AA, Flavell RA, Davis RJ. Disruption of the Jnk2 (Mapk9) gene reduces destructive insulitis and diabetes in a mouse model of type I diabetes. Proc Natl Acad Sci U S A. 2005 May 10; 102(19):6931-5.
    View in: PubMed
    Score: 0.014
  76. Gordon EJ, Wicker LS, Peterson LB, Serreze DV, Markees TG, Shultz LD, Rossini AA, Greiner DL, Mordes JP. Autoimmune diabetes and resistance to xenograft transplantation tolerance in NOD mice. Diabetes. 2005 Jan; 54(1):107-15.
    View in: PubMed
    Score: 0.014
  77. Banuelos SJ, Shultz LD, Greiner DL, Burzenski LM, Gott B, Lyons BL, Rossini AA, Appel MC. Rejection of human islets and human HLA-A2.1 transgenic mouse islets by alloreactive human lymphocytes in immunodeficient NOD-scid and NOD-Rag1(null)Prf1(null) mice. Clin Immunol. 2004 Sep; 112(3):273-83.
    View in: PubMed
    Score: 0.013
  78. Appel MC, Banuelos SJ, Greiner DL, Shultz LD, Mordes JP, Rossini AA. Prolonged survival of neonatal porcine islet xenografts in mice treated with a donor-specific transfusion and anti-CD154 antibody. Transplantation. 2004 May 15; 77(9):1341-9.
    View in: PubMed
    Score: 0.013
  79. Turgeon NA, Banuelos SJ, Shultz LD, Lyons BL, Iwakoshi N, Greiner DL, Mordes JP, Rossini AA, Appel MC. Alloimmune injury and rejection of human skin grafts on human peripheral blood lymphocyte-reconstituted non-obese diabetic severe combined immunodeficient beta2-microglobulin-null mice. Exp Biol Med (Maywood). 2003 Oct; 228(9):1096-104.
    View in: PubMed
    Score: 0.012
  80. Rossini AA, Mordes JP, Greiner DL, Stoff JS. Islet cell transplantation tolerance. Transplantation. 2001 Oct 27; 72(8 Suppl):S43-6.
    View in: PubMed
    Score: 0.011
  81. Ballen KK, Valinski H, Greiner D, Shultz LD, Becker PS, Hsieh CC, Stewart FM, Quesenberry PJ. Variables to predict engraftment of umbilical cord blood into immunodeficient mice: usefulness of the non-obese diabetic--severe combined immunodeficient assay. Br J Haematol. 2001 Jul; 114(1):211-8.
    View in: PubMed
    Score: 0.011
  82. Kollet O, Peled A, Byk T, Ben-Hur H, Greiner D, Shultz L, Lapidot T. beta2 microglobulin-deficient (B2m(null)) NOD/SCID mice are excellent recipients for studying human stem cell function. Blood. 2000 May 15; 95(10):3102-5.
    View in: PubMed
    Score: 0.010
  83. Ballen K, Becker PS, Greiner D, Valinski H, Shearin D, Berrios V, Dooner G, Hsieh CC, Wuu J, Shultz L, Cerny J, Leif J, Stewart FM, Quesenberry P. Effect of ex vivo cytokine treatment on human cord blood engraftment in NOD-scid mice. Br J Haematol. 2000 Mar; 108(3):629-40.
    View in: PubMed
    Score: 0.010
  84. Markees TG, Serreze DV, Phillips NE, Sorli CH, Gordon EJ, Shultz LD, Noelle RJ, Woda BA, Greiner DL, Mordes JP, Rossini AA. NOD mice have a generalized defect in their response to transplantation tolerance induction. Diabetes. 1999 May; 48(5):967-74.
    View in: PubMed
    Score: 0.009
  85. Christianson SW, Greiner DL, Hesselton RA, Leif JH, Wagar EJ, Schweitzer IB, Rajan TV, Gott B, Roopenian DC, Shultz LD. Enhanced human CD4+ T cell engraftment in beta2-microglobulin-deficient NOD-scid mice. J Immunol. 1997 Apr 15; 158(8):3578-86.
    View in: PubMed
    Score: 0.008
  86. Lowry PA, Shultz LD, Greiner DL, Hesselton RM, Kittler EL, Tiarks CY, Rao SS, Reilly J, Leif JH, Ramshaw H, Stewart FM, Quesenberry PJ. Improved engraftment of human cord blood stem cells in NOD/LtSz-scid/scid mice after irradiation or multiple-day injections into unirradiated recipients. Biol Blood Marrow Transplant. 1996 Feb; 2(1):15-23.
    View in: PubMed
    Score: 0.007
  87. Hesselton RM, Greiner DL, Mordes JP, Rajan TV, Sullivan JL, Shultz LD. High levels of human peripheral blood mononuclear cell engraftment and enhanced susceptibility to human immunodeficiency virus type 1 infection in NOD/LtSz-scid/scid mice. J Infect Dis. 1995 Oct; 172(4):974-82.
    View in: PubMed
    Score: 0.007
  88. Gerling IC, Friedman H, Greiner DL, Shultz LD, Leiter EH. Multiple low-dose streptozocin-induced diabetes in NOD-scid/scid mice in the absence of functional lymphocytes. Diabetes. 1994 Mar; 43(3):433-40.
    View in: PubMed
    Score: 0.006
  89. Serreze DV, Leiter EH, Christianson GJ, Greiner D, Roopenian DC. Major histocompatibility complex class I-deficient NOD-B2mnull mice are diabetes and insulitis resistant. Diabetes. 1994 Mar; 43(3):505-9.
    View in: PubMed
    Score: 0.006
  90. Rossini AA, Handler ES, Greiner DL, Mordes JP. Insulin dependent diabetes mellitus hypothesis of autoimmunity. Autoimmunity. 1991; 8(3):221-35.
    View in: PubMed
    Score: 0.005
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.