Header Logo

Connection

Neal Silverman to Signal Transduction

This is a "connection" page, showing publications Neal Silverman has written about Signal Transduction.
Connection Strength

3.013
  1. West C, Silverman N. p38b and JAK-STAT signaling protect against Invertebrate iridescent virus 6 infection in Drosophila. PLoS Pathog. 2018 05; 14(5):e1007020.
    View in: PubMed
    Score: 0.299
  2. Kleino A, Ramia NF, Bozkurt G, Shen Y, Nailwal H, Huang J, Napetschnig J, Gangloff M, Chan FK, Wu H, Li J, Silverman N. Peptidoglycan-Sensing Receptors Trigger the Formation of Functional Amyloids of the Adaptor Protein Imd to Initiate Drosophila NF-?B Signaling. Immunity. 2017 10 17; 47(4):635-647.e6.
    View in: PubMed
    Score: 0.287
  3. Chen L, Paquette N, Mamoor S, Rus F, Nandy A, Leszyk J, Shaffer SA, Silverman N. Innate immune signaling in Drosophila is regulated by transforming growth factor ? (TGF?)-activated kinase (Tak1)-triggered ubiquitin editing. J Biol Chem. 2017 05 26; 292(21):8738-8749.
    View in: PubMed
    Score: 0.277
  4. Rus F, Flatt T, Tong M, Aggarwal K, Okuda K, Kleino A, Yates E, Tatar M, Silverman N. Ecdysone triggered PGRP-LC expression controls Drosophila innate immunity. EMBO J. 2013 May 29; 32(11):1626-38.
    View in: PubMed
    Score: 0.211
  5. Ganesan S, Aggarwal K, Paquette N, Silverman N. NF-?B/Rel proteins and the humoral immune responses of Drosophila melanogaster. Curr Top Microbiol Immunol. 2011; 349:25-60.
    View in: PubMed
    Score: 0.179
  6. Paquette N, Broemer M, Aggarwal K, Chen L, Husson M, Ert?rk-Hasdemir D, Reichhart JM, Meier P, Silverman N. Caspase-mediated cleavage, IAP binding, and ubiquitination: linking three mechanisms crucial for Drosophila NF-kappaB signaling. Mol Cell. 2010 Jan 29; 37(2):172-82.
    View in: PubMed
    Score: 0.168
  7. Aggarwal K, Rus F, Vriesema-Magnuson C, Ert?rk-Hasdemir D, Paquette N, Silverman N. Rudra interrupts receptor signaling complexes to negatively regulate the IMD pathway. PLoS Pathog. 2008 Aug 08; 4(8):e1000120.
    View in: PubMed
    Score: 0.152
  8. Kaneko T, Silverman N. Bacterial recognition and signalling by the Drosophila IMD pathway. Cell Microbiol. 2005 Apr; 7(4):461-9.
    View in: PubMed
    Score: 0.120
  9. Kaneko T, Golenbock D, Silverman N. Peptidoglycan recognition by the Drosophila Imd pathway. J Endotoxin Res. 2005; 11(6):383-9.
    View in: PubMed
    Score: 0.118
  10. Bharadwaj R, Jaiswal S, Silverman N. Cytosolic delivery of innate immune agonists. Trends Immunol. 2024 Dec; 45(12):1001-1014.
    View in: PubMed
    Score: 0.117
  11. Kaneko T, Goldman WE, Mellroth P, Steiner H, Fukase K, Kusumoto S, Harley W, Fox A, Golenbock D, Silverman N. Monomeric and polymeric gram-negative peptidoglycan but not purified LPS stimulate the Drosophila IMD pathway. Immunity. 2004 May; 20(5):637-49.
    View in: PubMed
    Score: 0.113
  12. Silverman N. Flies kNOw how to signal. Dev Cell. 2003 Jan; 4(1):5-6.
    View in: PubMed
    Score: 0.103
  13. Kleino A, Silverman N. Regulation of the Drosophila Imd pathway by signaling amyloids. Insect Biochem Mol Biol. 2019 05; 108:16-23.
    View in: PubMed
    Score: 0.079
  14. Paik D, Monahan A, Caffrey DR, Elling R, Goldman WE, Silverman N. SLC46 Family Transporters Facilitate Cytosolic Innate Immune Recognition of Monomeric Peptidoglycans. J Immunol. 2017 07 01; 199(1):263-270.
    View in: PubMed
    Score: 0.070
  15. Monahan A, Kleino A, Silverman N. ReaDAPting the Role of PGRP-SD in Bacterial Sensing and Immune Activation. Immunity. 2016 11 15; 45(5):951-953.
    View in: PubMed
    Score: 0.067
  16. Liu B, Zheng Y, Yin F, Yu J, Silverman N, Pan D. Toll Receptor-Mediated Hippo Signaling Controls Innate Immunity in Drosophila. Cell. 2016 Jan 28; 164(3):406-19.
    View in: PubMed
    Score: 0.064
  17. Kim CH, Paik D, Rus F, Silverman N. The caspase-8 homolog Dredd cleaves Imd and Relish but is not inhibited by p35. J Biol Chem. 2014 Jul 18; 289(29):20092-101.
    View in: PubMed
    Score: 0.057
  18. Kleino A, Silverman N. The Drosophila IMD pathway in the activation of the humoral immune response. Dev Comp Immunol. 2014 Jan; 42(1):25-35.
    View in: PubMed
    Score: 0.053
  19. Rus F, Morlock K, Silverman N, Pham N, Kotwal GJ, Marshall WL. Characterization of poxvirus-encoded proteins that regulate innate immune signaling pathways. Methods Mol Biol. 2012; 890:273-88.
    View in: PubMed
    Score: 0.048
  20. Boyer L, Magoc L, Dejardin S, Cappillino M, Paquette N, Hinault C, Charriere GM, Ip WK, Fracchia S, Hennessy E, Erturk-Hasdemir D, Reichhart JM, Silverman N, Lacy-Hulbert A, Stuart LM. Pathogen-derived effectors trigger protective immunity via activation of the Rac2 enzyme and the IMD or Rip kinase signaling pathway. Immunity. 2011 Oct 28; 35(4):536-49.
    View in: PubMed
    Score: 0.047
  21. Aggarwal K, Silverman N. Positive and negative regulation of the Drosophila immune response. BMB Rep. 2008 Apr 30; 41(4):267-77.
    View in: PubMed
    Score: 0.037
  22. Aggrawal K, Silverman N. Peptidoglycan recognition in Drosophila. Biochem Soc Trans. 2007 Dec; 35(Pt 6):1496-500.
    View in: PubMed
    Score: 0.036
  23. Sweet CR, Conlon J, Golenbock DT, Goguen J, Silverman N. YopJ targets TRAF proteins to inhibit TLR-mediated NF-kappaB, MAPK and IRF3 signal transduction. Cell Microbiol. 2007 Nov; 9(11):2700-15.
    View in: PubMed
    Score: 0.035
  24. Wu L, Silverman N. Fighting infection fly-style. Fly (Austin). 2007 Mar-Apr; 1(2):106-9.
    View in: PubMed
    Score: 0.034
  25. Cherry S, Silverman N. Host-pathogen interactions in drosophila: new tricks from an old friend. Nat Immunol. 2006 Sep; 7(9):911-7.
    View in: PubMed
    Score: 0.033
  26. Kaneko T, Yano T, Aggarwal K, Lim JH, Ueda K, Oshima Y, Peach C, Erturk-Hasdemir D, Goldman WE, Oh BH, Kurata S, Silverman N. PGRP-LC and PGRP-LE have essential yet distinct functions in the drosophila immune response to monomeric DAP-type peptidoglycan. Nat Immunol. 2006 Jul; 7(7):715-23.
    View in: PubMed
    Score: 0.033
  27. Avila A, Silverman N, Diaz-Meco MT, Moscat J. The Drosophila atypical protein kinase C-ref(2)p complex constitutes a conserved module for signaling in the toll pathway. Mol Cell Biol. 2002 Dec; 22(24):8787-95.
    View in: PubMed
    Score: 0.026
  28. Pereira M, Durso DF, Bryant CE, Kurt-Jones EA, Silverman N, Golenbock DT, Gazzinelli RT. The IRAK4 scaffold integrates TLR4-driven TRIF and MYD88 signaling pathways. Cell Rep. 2022 08 16; 40(7):111225.
    View in: PubMed
    Score: 0.025
  29. Zheng W, Rus F, Hernandez A, Kang P, Goldman W, Silverman N, Tatar M. Dehydration triggers ecdysone-mediated recognition-protein priming and elevated anti-bacterial immune responses in Drosophila Malpighian tubule renal cells. BMC Biol. 2018 05 31; 16(1):60.
    View in: PubMed
    Score: 0.019
  30. Akula MK, Shi M, Jiang Z, Foster CE, Miao D, Li AS, Zhang X, Gavin RM, Forde SD, Germain G, Carpenter S, Rosadini CV, Gritsman K, Chae JJ, Hampton R, Silverman N, Gravallese EM, Kagan JC, Fitzgerald KA, Kastner DL, Golenbock DT, Bergo MO, Wang D. Control of the innate immune response by the mevalonate pathway. Nat Immunol. 2016 08; 17(8):922-9.
    View in: PubMed
    Score: 0.016
  31. Buchon N, Silverman N, Cherry S. Immunity in Drosophila melanogaster--from microbial recognition to whole-organism physiology. Nat Rev Immunol. 2014 Dec; 14(12):796-810.
    View in: PubMed
    Score: 0.015
  32. Donlea JM, Ramanan N, Silverman N, Shaw PJ. Genetic rescue of functional senescence in synaptic and behavioral plasticity. Sleep. 2014 Sep 01; 37(9):1427-37.
    View in: PubMed
    Score: 0.014
  33. Warmbold C, Uliczka K, Rus F, Suck R, Petersen A, Silverman N, Ulmer AJ, Heine H, Roeder T. Dermatophagoides pteronyssinus major allergen 1 activates the innate immune response of the fruit fly Drosophila melanogaster. J Immunol. 2013 Jan 01; 190(1):366-71.
    View in: PubMed
    Score: 0.013
  34. Bossaller L, Chiang PI, Schmidt-Lauber C, Ganesan S, Kaiser WJ, Rathinam VA, Mocarski ES, Subramanian D, Green DR, Silverman N, Fitzgerald KA, Marshak-Rothstein A, Latz E. Cutting edge: FAS (CD95) mediates noncanonical IL-1? and IL-18 maturation via caspase-8 in an RIP3-independent manner. J Immunol. 2012 Dec 15; 189(12):5508-12.
    View in: PubMed
    Score: 0.013
  35. Mitchell JA, Fitzgerald KA, Coyle A, Silverman N, Cartwright N. TOLLing away in Brazil. Nat Immunol. 2006 Jul; 7(7):675-9.
    View in: PubMed
    Score: 0.008
  36. Lim JH, Kim MS, Kim HE, Yano T, Oshima Y, Aggarwal K, Goldman WE, Silverman N, Kurata S, Oh BH. Structural basis for preferential recognition of diaminopimelic acid-type peptidoglycan by a subset of peptidoglycan recognition proteins. J Biol Chem. 2006 Mar 24; 281(12):8286-95.
    View in: PubMed
    Score: 0.008
  37. Zhou R, Silverman N, Hong M, Liao DS, Chung Y, Chen ZJ, Maniatis T. The role of ubiquitination in Drosophila innate immunity. J Biol Chem. 2005 Oct 07; 280(40):34048-55.
    View in: PubMed
    Score: 0.008
  38. Zhuang ZH, Zhou Y, Yu MC, Silverman N, Ge BX. Regulation of Drosophila p38 activation by specific MAP2 kinase and MAP3 kinase in response to different stimuli. Cell Signal. 2006 Apr; 18(4):441-8.
    View in: PubMed
    Score: 0.008
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.