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TBX22 missense mutations found in patients with X-linked cleft palate affect DNA binding, sumoylation, and transcriptional repression.
Tbx22null mice have a submucous cleft palate due to reduced palatal bone formation and also display ankyloglossia and choanal atresia phenotypes.
TDP-43-The key to understanding amyotrophic lateral sclerosis.
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TDP-43-The key to understanding amyotrophic lateral sclerosis.
Xu Z, Yang C. TDP-43-The key to understanding amyotrophic lateral sclerosis. Rare Dis. 2014; 2(1):e944443.
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Zuoshang Xu MD, PhD