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Connection

Cole Haynes to Unfolded Protein Response

This is a "connection" page, showing publications Cole Haynes has written about Unfolded Protein Response.
Connection Strength

12.063
  1. Mallick A, Haynes CM. Methods to analyze the mitochondrial unfolded protein response (UPRmt). Methods Enzymol. 2024; 707:543-564.
    View in: PubMed
    Score: 0.876
  2. Anderson NS, Haynes CM. Folding the Mitochondrial UPR into the Integrated Stress Response. Trends Cell Biol. 2020 06; 30(6):428-439.
    View in: PubMed
    Score: 0.648
  3. Naresh NU, Haynes CM. Signaling and Regulation of the Mitochondrial Unfolded Protein Response. Cold Spring Harb Perspect Biol. 2019 06 03; 11(6).
    View in: PubMed
    Score: 0.612
  4. Deng P, Uma Naresh N, Du Y, Lamech LT, Yu J, Zhu LJ, Pukkila-Worley R, Haynes CM. Mitochondrial UPR repression during Pseudomonas aeruginosa infection requires the bZIP protein ZIP-3. Proc Natl Acad Sci U S A. 2019 03 26; 116(13):6146-6151.
    View in: PubMed
    Score: 0.601
  5. Melber A, Haynes CM. UPRmt regulation and output: a stress response mediated by mitochondrial-nuclear communication. Cell Res. 2018 Mar; 28(3):281-295.
    View in: PubMed
    Score: 0.558
  6. Shpilka T, Haynes CM. The mitochondrial UPR: mechanisms, physiological functions and implications in ageing. Nat Rev Mol Cell Biol. 2018 02; 19(2):109-120.
    View in: PubMed
    Score: 0.550
  7. Deng P, Haynes CM. Mitochondrial dysfunction in cancer: Potential roles of ATF5 and the mitochondrial UPR. Semin Cancer Biol. 2017 12; 47:43-49.
    View in: PubMed
    Score: 0.530
  8. Fiorese CJ, Haynes CM. Integrating the UPRmt into the mitochondrial maintenance network. Crit Rev Biochem Mol Biol. 2017 06; 52(3):304-313.
    View in: PubMed
    Score: 0.522
  9. Deng P, Haynes CM. The mitokine quest(ion). Cell Res. 2016 12; 26(12):1265-1266.
    View in: PubMed
    Score: 0.514
  10. Lin YF, Schulz AM, Pellegrino MW, Lu Y, Shaham S, Haynes CM. Maintenance and propagation of a deleterious mitochondrial genome by the mitochondrial unfolded protein response. Nature. 2016 05 19; 533(7603):416-9.
    View in: PubMed
    Score: 0.494
  11. Lin YF, Haynes CM. Metabolism and the UPR(mt). Mol Cell. 2016 Mar 03; 61(5):677-682.
    View in: PubMed
    Score: 0.488
  12. Lamech LT, Haynes CM. The unpredictability of prolonged activation of stress response pathways. J Cell Biol. 2015 Jun 22; 209(6):781-7.
    View in: PubMed
    Score: 0.465
  13. Schulz AM, Haynes CM. UPR(mt)-mediated cytoprotection and organismal aging. Biochim Biophys Acta. 2015 Nov; 1847(11):1448-56.
    View in: PubMed
    Score: 0.458
  14. Pellegrino MW, Haynes CM. Mitophagy and the mitochondrial unfolded protein response in neurodegeneration and bacterial infection. BMC Biol. 2015 Apr 03; 13:22.
    View in: PubMed
    Score: 0.458
  15. Haynes C, Powell K. Cole Haynes: on the trail of mitochondrial dysfunction. J Cell Biol. 2015 Jan 19; 208(2):140-1.
    View in: PubMed
    Score: 0.452
  16. Pellegrino MW, Nargund AM, Kirienko NV, Gillis R, Fiorese CJ, Haynes CM. Mitochondrial UPR-regulated innate immunity provides resistance to pathogen infection. Nature. 2014 Dec 18; 516(7531):414-7.
    View in: PubMed
    Score: 0.442
  17. Haynes CM, Fiorese CJ, Lin YF. Evaluating and responding to mitochondrial dysfunction: the mitochondrial unfolded-protein response and beyond. Trends Cell Biol. 2013 Jul; 23(7):311-8.
    View in: PubMed
    Score: 0.397
  18. Nargund AM, Pellegrino MW, Fiorese CJ, Baker BM, Haynes CM. Mitochondrial import efficiency of ATFS-1 regulates mitochondrial UPR activation. Science. 2012 Aug 03; 337(6094):587-90.
    View in: PubMed
    Score: 0.377
  19. Pellegrino MW, Nargund AM, Haynes CM. Signaling the mitochondrial unfolded protein response. Biochim Biophys Acta. 2013 Feb; 1833(2):410-6.
    View in: PubMed
    Score: 0.371
  20. Haynes CM, Ron D. The mitochondrial UPR - protecting organelle protein homeostasis. J Cell Sci. 2010 Nov 15; 123(Pt 22):3849-55.
    View in: PubMed
    Score: 0.338
  21. Haynes CM, Yang Y, Blais SP, Neubert TA, Ron D. The matrix peptide exporter HAF-1 signals a mitochondrial UPR by activating the transcription factor ZC376.7 in C. elegans. Mol Cell. 2010 Feb 26; 37(4):529-40.
    View in: PubMed
    Score: 0.322
  22. Kim S, Ramalho TR, Haynes CM. Regulation of proteostasis and innate immunity via mitochondria-nuclear communication. J Cell Biol. 2024 03 04; 223(3).
    View in: PubMed
    Score: 0.212
  23. Uma Naresh N, Kim S, Shpilka T, Yang Q, Du Y, Haynes CM. Mitochondrial genome recovery by ATFS-1 is essential for development after starvation. Cell Rep. 2022 12 27; 41(13):111875.
    View in: PubMed
    Score: 0.196
  24. Haynes CM, Hekimi S. Mitochondrial dysfunction, aging, and the mitochondrial unfolded protein response in Caenorhabditis elegans. Genetics. 2022 11 30; 222(4).
    View in: PubMed
    Score: 0.195
  25. Shpilka T, Du Y, Yang Q, Melber A, Uma Naresh N, Lavelle J, Kim S, Liu P, Weidberg H, Li R, Yu J, Zhu LJ, Strittmatter L, Haynes CM. UPRmt scales mitochondrial network expansion with protein synthesis via mitochondrial import in Caenorhabditis elegans. Nat Commun. 2021 01 20; 12(1):479.
    View in: PubMed
    Score: 0.171
  26. Wang YT, Lim Y, McCall MN, Huang KT, Haynes CM, Nehrke K, Brookes PS. Cardioprotection by the mitochondrial unfolded protein response requires ATF5. Am J Physiol Heart Circ Physiol. 2019 08 01; 317(2):H472-H478.
    View in: PubMed
    Score: 0.154
  27. Qureshi MA, Haynes CM, Pellegrino MW. The mitochondrial unfolded protein response: Signaling from the powerhouse. J Biol Chem. 2017 08 18; 292(33):13500-13506.
    View in: PubMed
    Score: 0.134
  28. Fiorese CJ, Schulz AM, Lin YF, Rosin N, Pellegrino MW, Haynes CM. The Transcription Factor ATF5 Mediates a Mammalian Mitochondrial UPR. Curr Biol. 2016 08 08; 26(15):2037-2043.
    View in: PubMed
    Score: 0.125
  29. Mohrin M, Shin J, Liu Y, Brown K, Luo H, Xi Y, Haynes CM, Chen D. Stem cell aging. A mitochondrial UPR-mediated metabolic checkpoint regulates hematopoietic stem cell aging. Science. 2015 Mar 20; 347(6228):1374-7.
    View in: PubMed
    Score: 0.114
  30. Nargund AM, Fiorese CJ, Pellegrino MW, Deng P, Haynes CM. Mitochondrial and nuclear accumulation of the transcription factor ATFS-1 promotes OXPHOS recovery during the UPR(mt). Mol Cell. 2015 Apr 02; 58(1):123-33.
    View in: PubMed
    Score: 0.114
  31. Baker BM, Nargund AM, Sun T, Haynes CM. Protective coupling of mitochondrial function and protein synthesis via the eIF2a kinase GCN-2. PLoS Genet. 2012; 8(6):e1002760.
    View in: PubMed
    Score: 0.094
  32. Wiseman RL, Haynes CM, Ron D. SnapShot: The unfolded protein response. Cell. 2010 Feb 19; 140(4):590-590.e2.
    View in: PubMed
    Score: 0.080
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.