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Diogo Magnani PhD

TitleAssociate Professor
InstitutionUMass Chan Medical School
DepartmentMedicine
AddressMassBiologics
460 Walk Hill Street
Boston MA 02126
Phone617-474-4069
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    Other Positions
    InstitutionT.H. Chan School of Medicine
    DepartmentMedicine
    DivisionInnate Immunity


    Collapse Biography 
    Collapse education and training
    Federal University of Minas Gerais, Belo Horizonte, MG, BrazilBSBiology
    Federal University of Minas Gerais, Belo Horizonte, MG, BrazilMSBiochemistry & Immunology
    University of Wisconsin, Madison, Madison, WI, United StatesPHDBiomedical Sciences

    Collapse Overview 

    Collapse Research 
    Collapse research activities and funding
    R24OD010976     (MAGNANI, DIOGO)Sep 1, 2000 - Nov 30, 2019
    NIH
    Resource fo Nonhuman Primate Cell Depleting Antibodies
    Role: Principal Investigator

    W81XWH-18-1-0094/A     (Diogo Magnani)Nov 1, 2018 - Oct 30, 2021
    Department of Defense
    A Fetus-Targeted Antibody Therapy to Prevent Zika Virus Infection During Pregnancy
    Role Description: The goal of this proposal is to generate bi-specific Zika virus-neutralizing antibodies with asymmetric heavy chain mutations to enhance transplacental antibody transport and prevent infection of the fetus.
    Role: PI

    U24AI126683     (Diogo Magnani)May 31, 2019 - May 31, 2021
    NIH NIAID
    Preclinical evaluation of rhesus ATG as a depletional induction agent in rhesus macaques
    Role Description: Preclinical evaluation of rhesus ATG as a depletional induction agent in rhesus macaques
    Role: PI

    P40OD028116     (MAGNANI, DIOGO)Jan 1, 2020 - Dec 31, 2024
    NIH
    Nonhuman Primate Antibody Resource for Immune Cell Depletion
    Role: Principal Investigator

    U24AI126683-05S1     (Diogo Magnani)Apr 13, 2020 - Apr 12, 2021
    NIH NIAID (PI)
    Nonhuman primate reagent resource – Supplement
    Role Description: Our proposal will also establish large-scale industrial methodologies for producing and purifying viral antigens, shall they become necessary in the future.
    Role: PI

    U24AI126683     (MAGNANI, DIOGO)Jun 1, 2020 - May 31, 2021
    NIH
    Nonhuman Primate Reagent Resource
    Role: Principal Investigator

    P40OD028116     (Diogo Magnani)Jul 1, 2020 - Dec 31, 2020
    NIH / ORIP
    Coronavirus-specific antibodies for nonhuman primate research
    Role Description: Our recombinant standard reagents will support the development of rigorous coronavirus-specific antibody assays for nonhuman primate research and colony management.
    Role: PI

         (Jonah Sacha)Aug 1, 2020 - Jun 30, 2025
    NIH
    A long-acting CCR5 monoclonal antibody for HIV prevention
    Role Description: The administration of antibodies blocking viral receptors has the potential to be effective in protecting the host against infection. The proposed studies are aimed at understanding the potential of a half-life extended antibody against the co-receptor of AIDS viruses, CCR5, in prevention of viral acquisition against challenges via different routes.
    Role: Subaward PI

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Hahn PA, Shandilya S, da Costa LAB, da Silva LCF, O'Hagan D, Liang B, Engelman K, Gardner MR, Gao G, Fuchs SP, Martinez-Navio JM, Desrosiers RC, Ardeshir A, Magnani DM, Martins MA. The Immunogenicity of AAV-Encoded HIV-1 bNAbs in Rhesus Macaques Is Unaffected by a Short Course of the Immunomodulator CTLA4Ig. AIDS Res Hum Retroviruses. 2025 Aug 20. PMID: 40833809.
      Citations:    
    2. Piekniewska A, Roelandse M, Lloyd KCK, Korf I, Voss SR, de Castro G, Magnani DM, Varga Z, James-Zorn C, Horb M, Grethe JS, Bandrowski A. Do organisms need an impact factor? Citations of key biological resources including model organisms reveal usage patterns and impact. PLoS One. 2025; 20(8):e0327344. PMID: 40802618.
      Citations:    
    3. Ardeshir A, O'Hagan D, Mehta I, Shandilya S, Hopkins LLJ, Adamson L, Kuroda MJ, Hahn PA, da Costa LAB, Fuchs SP, Martinez-Navio JM, Gardner MR, Van Rompay KKA, Magnani DM, Lifson JD, Gao G, Farzan M, Desrosiers RC, Das J, Martins MA. Determinants of successful AAV-vectored delivery of HIV-1 bNAbs in early life. Nature. 2025 Sep; 645(8082):1020-1028. PMID: 40739359.
      Citations:    
    4. Araki D, Hong SG, Linde N, Fisk B, Redekar N, Salisbury-Ruf C, Krouse A, Engels T, Golomb J, Dagur P, Panicker SR, Kanthi Y, Magnani DM, Wang Z, Larochelle A. cMPL-based purification and depletion of human hematopoietic stem cells: implications for pretransplant conditioning. Blood. 2025 Jun 19; 145(25):2978-2991. PMID: 40009502.
      Citations:    
    5. Melton A, Potter EL, Penney T, Krzykwa C, Rowe LA, Goff K, Scheuermann SE, Russell-Lodrigue K, Melton HJ, Magnani DM, Kolls JK, Blair RV, Maness NJ. Distinct transcriptomic signatures in pulmonary tissue resident and vascular resident-like T cells in nonhuman primates. iScience. 2025 Jun 20; 28(6):112745. PMID: 40546965.
      Citations:    
    6. Anwar IJ, DeLaura I, Ladowski JM, Schilir? D, Gao Q, Manook M, Yoon J, Belloni R, Park A, Schuster DJ, Song M, Lin L, Farris AB, Magnani D, Williams K, Kwun J, Knechtle SJ. CD154 blockade effectively controls antibody-mediated rejection in highly sensitized nonhuman primate kidney transplant recipients. Sci Transl Med. 2025 Jan; 17(779):eadn8130. PMID: 39742504.
      Citations:    
    7. Dankwa S, Kosman C, Dennis M, Giorgi EE, Vuong K, Pahountis I, Garza A, Binuya C, McCarthy J, Mayer BT, Ngo JT, Enemuo CA, Carnathan DG, Stanfield-Oakley S, Berendam SJ, Weinbaum C, Engelman K, Magnani DM, Chan C, Ferrari G, Silvestri G, Amara RR, Chahroudi A, Permar SR, Fouda GG, Goswami R. A novel HIV triple broadly neutralizing antibody (bNAb) combination-based passive immunization of infant rhesus macaques achieves durable protective plasma neutralization levels and mediates anti-viral effector functions. PLoS One. 2024; 19(11):e0312411. PMID: 39527587.
      Citations:    
    8. Zikos J, Webb GM, Wu HL, Reed JS, Watanabe J, Usachenko JL, Shaqra AM, Schiffer CA, Van Rompay KKA, Sacha JB, Magnani DM. FcRn-enhancing mutations lead to increased and prolonged levels of the HIV CCR5-blocking monoclonal antibody leronlimab in the fetuses and newborns of pregnant rhesus macaques. MAbs. 2024 Jan-Dec; 16(1):2406788. PMID: 39324549.
      Citations:    
    9. Sutton MS, Bucsan AN, Lehman CC, Kamath M, Pokkali S, Magnani DM, Seder R, Darrah PA, Roederer M. Antibody-mediated depletion of select leukocyte subsets in blood and tissue of nonhuman primates. Front Immunol. 2024; 15:1359679. PMID: 38529287.
      Citations:    
    10. Araki D, Hong S, Linde N, Fisk B, Redekar N, Salisbury-Ruf C, Krouse A, Engels T, Golomb J, Dagur P, Magnani DM, Wang Z, Larochelle A. cMPL-Based Purification and Depletion of Human Hematopoietic Stem Cells: Implications for Pre-Transplant Conditioning. bioRxiv. 2024 Feb 28. PMID: 38464076.
      Citations:    
    11. Piekniewska A, Anderson N, Roelandse M, Lloyd KCK, Korf I, Voss SR, de Castro G, Magnani DM, Varga Z, James-Zorn C, Horb M, Grethe JS, Bandrowski A. Do organisms need an impact factor? Citations of key biological resources including model organisms reveal usage patterns and impact. bioRxiv. 2024 Jan 16. PMID: 38293091.
      Citations:    
    12. DeLaura I, Zikos J, Anwar IJ, Yoon J, Ladowski J, Jackson A, Van Rompay K, Magnani D, Knechtle SJ, Kwun J. The impact of IdeS (imlifidase) on allo-specific, xeno-reactive, and protective antibodies in a sensitized rhesus macaque model. Xenotransplantation. 2024 Jan-Feb; 31(1):e12833. PMID: 37864433.
      Citations:    
    13. Deere JD, Merriam D, Leggat KM, Chang WW, M?ndez-Lagares G, Kieu H, Dutra J, Fontaine J, Lu W, Chin N, Chen C, Tran BC, Salinas J, Miller CN, Deeks SG, Lifson JD, Engelman K, Magnani D, Reimann K, Stevenson M, Hartigan-O'Connor DJ. SIV clearance from neonatal macaques following transient CCR5 depletion. bioRxiv. 2023 May 01. PMID: 37205470.
      Citations:    
    14. Petitpas K, Habibabady Z, Ritchie V, Connolly MR, Burdorf L, Qin W, Kan Y, Layer JV, Crabtree JN, Youd ME, Westlin WF, Magnani DM, Pierson RN, Azimzadeh AM. Genetic modifications designed for xenotransplantation attenuate sialoadhesin-dependent binding of human erythrocytes to porcine macrophages. Xenotransplantation. 2022 11; 29(6):e12780. PMID: 36125388.
      Citations:    
    15. Silveira CGT, Magnani DM, Costa PR, Avelino-Silva VI, Ricciardi MJ, Timenetsky MDCST, Goulart R, Correia CA, Marmorato MP, Ferrari L, Nakagawa ZB, Tomiyama C, Tomiyama H, Kalil J, Palacios R, Precioso AR, Watkins DI, Kall?s EG. Plasmablast Expansion Following the Tetravalent, Live-Attenuated Dengue Vaccine Butantan-DV in DENV-Na?ve and DENV-Exposed Individuals in a Brazilian Cohort. Front Immunol. 2022; 13:908398. PMID: 35837409.
      Citations:    
    16. Duggan NN, Weisgrau KL, Magnani DM, Rakasz EG, Desrosiers RC, Martinez-Navio JM. SOSIP Trimer-Specific Antibodies Isolated from a Simian-Human Immunodeficiency Virus-Infected Monkey with versus without a Pre-blocking Step with gp41. J Virol. 2022 01 26; 96(2):e0158221. PMID: 34730398.
      Citations:    
    17. Crowley AR, Osei-Owusu NY, Dekkers G, Gao W, Wuhrer M, Magnani DM, Reimann KA, Pincus SH, Vidarsson G, Ackerman ME. Biophysical Evaluation of Rhesus Macaque Fc Gamma Receptors Reveals Similar IgG Fc Glycoform Preferences to Human Receptors. Front Immunol. 2021; 12:754710. PMID: 34712242.
      Citations:    
    18. Chang XL, Webb GM, Wu HL, Greene JM, Abdulhaqq S, Bateman KB, Reed JS, Pessoa C, Weber WC, Maier N, Chew GM, Gilbride RM, Gao L, Agnor R, Giobbi T, Torgerson J, Siess D, Burnett N, Fischer M, Shiel O, Moats C, Patterson B, Dhody K, Kelly S, Pourhassan N, Magnani DM, Smedley J, Bimber BN, Haigwood NL, Hansen SG, Brown TR, Ndhlovu LC, Sacha JB. Antibody-based CCR5 blockade protects Macaques from mucosal SHIV transmission. Nat Commun. 2021 06 07; 12(1):3343. PMID: 34099693.
      Citations:    
    19. Manook M, Flores WJ, Schmitz R, Fitch Z, Yoon J, Bae Y, Shaw B, Kirk A, Harnois M, Permar S, Farris AB, Magnani DM, Kwun J, Knechtle S. Measuring the Impact of Targeting FcRn-Mediated IgG Recycling on Donor-Specific Alloantibodies in a Sensitized NHP Model. Front Immunol. 2021; 12:660900. PMID: 34149698.
      Citations:    
    20. Shaw BI, Schmitz R, Flores WJ, Magnani DM, Li J, Song M, Kirk AD. A comparative study of human-and rhesus-specific antithymocyte globulins in Rhesus macaques. Clin Transplant. 2021 08; 35(8):e14369. PMID: 34021521.
      Citations:    
    21. Schouest B, Beddingfield BJ, Gilbert MH, Bohm RP, Schiro F, Aye PP, Panganiban AT, Magnani DM, Maness NJ. Zika virus infection during pregnancy protects against secondary infection in the absence of CD8+ cells. Virology. 2021 07; 559:100-110. PMID: 33865073.
      Citations:    
    22. Pedre?o-Lopez N, Rosen BC, Flores WJ, Gorman MJ, Voigt TB, Ricciardi MJ, Crosno K, Weisgrau KL, Parks CL, Lifson JD, Alter G, Rakasz EG, Magnani DM, Martins MA, Watkins DI. Non-neutralizing Antibodies May Contribute to Suppression of SIVmac239 Viremia in Indian Rhesus Macaques. Front Immunol. 2021; 12:657424. PMID: 33796119.
      Citations:    
    23. Pedre?o-Lopez N, Dang CM, Rosen BC, Ricciardi MJ, Bailey VK, Gutman MJ, Gonzalez-Nieto L, Pauthner MG, Le K, Song G, Andrabi R, Weisgrau KL, Pomplun N, Martinez-Navio JM, Fuchs SP, Wrammert J, Rakasz EG, Lifson JD, Martins MA, Burton DR, Watkins DI, Magnani DM. Induction of Transient Virus Replication Facilitates Antigen-Independent Isolation of SIV-Specific Monoclonal Antibodies. Mol Ther Methods Clin Dev. 2020 Mar 13; 16:225-237. PMID: 32083148.
      Citations:    
    24. Magnani DM, Sassi FC, Vana LPM, Andrade CRF. Correlation between scar assessment scales and orofacial myofunctional disorders in patients with head and neck burns. Codas. 2019; 31(5):e20180238. PMID: 31618317.
      Citations: 2     Fields:    Translation:Humans
    25. Gonzalez-Nieto L, Castro IM, Bischof GF, Shin YC, Ricciardi MJ, Bailey VK, Dang CM, Pedre?o-Lopez N, Magnani DM, Ejima K, Allison DB, Gil HM, Evans DT, Rakasz EG, Lifson JD, Desrosiers RC, Martins MA. Vaccine protection against rectal acquisition of SIVmac239 in rhesus macaques. PLoS Pathog. 2019 09; 15(9):e1008015. PMID: 31568531.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    26. Maness NJ, Schouest B, Singapuri A, Dennis M, Gilbert MH, Bohm RP, Schiro F, Aye PP, Baker K, Van Rompay KKA, Lackner AA, Bonaldo MC, Blair RV, Permar SR, Coffey LL, Panganiban AT, Magnani D. Postnatal Zika virus infection of nonhuman primate infants born to mothers infected with homologous Brazilian Zika virus. Sci Rep. 2019 09 05; 9(1):12802. PMID: 31488856.
      Citations:    
    27. Grubaugh ND, Saraf S, Gangavarapu K, Watts A, Tan AL, Oidtman RJ, Ladner JT, Oliveira G, Matteson NL, Kraemer MUG, Vogels CBF, Hentoff A, Bhatia D, Stanek D, Scott B, Landis V, Stryker I, Cone MR, Kopp EW, Cannons AC, Heberlein-Larson L, White S, Gillis LD, Ricciardi MJ, Kwal J, Lichtenberger PK, Magnani DM, Watkins DI, Palacios G, Hamer DH, Gardner LM, Perkins TA, Baele G, Khan K, Morrison A, Isern S, Michael SF, Andersen KG. Travel Surveillance and Genomics Uncover a Hidden Zika Outbreak during the Waning Epidemic. Cell. 2019 08 22; 178(5):1057-1071.e11. PMID: 31442400.
      Citations: 38     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    28. Shim BS, Kwon YC, Ricciardi MJ, Stone M, Otsuka Y, Berri F, Kwal JM, Magnani DM, Jackson CB, Richard AS, Norris P, Busch M, Curry CL, Farzan M, Watkins D, Choe H. Zika Virus-Immune Plasmas from Symptomatic and Asymptomatic Individuals Enhance Zika Pathogenesis in Adult and Pregnant Mice. mBio. 2019 07 02; 10(4). PMID: 31266863.
      Citations: 24     Fields:    Translation:HumansAnimalsCells
    29. Martins MA, Gonzalez-Nieto L, Shin YC, Domingues A, Gutman MJ, Maxwell HS, Magnani DM, Ricciardi MJ, Pedre?o-Lopez N, Bailey VK, Altman JD, Parks CL, Allison DB, Ejima K, Rakasz EG, Capuano S, Desrosiers RC, Lifson JD, Watkins DI. The Frequency of Vaccine-Induced T-Cell Responses Does Not Predict the Rate of Acquisition after Repeated Intrarectal SIVmac239 Challenges in Mamu-B*08+ Rhesus Macaques. J Virol. 2019 03 01; 93(5). PMID: 30541854.
      Citations: 4     Fields:    Translation:AnimalsCellsPHPublic Health
    30. Martins MA, Tully DC, Pedre?o-Lopez N, von Bredow B, Pauthner MG, Shin YC, Yuan M, Lima NS, Bean DJ, Gonzalez-Nieto L, Domingues A, Gutman MJ, Maxwell HS, Magnani DM, Ricciardi MJ, Bailey VK, Altman JD, Burton DR, Ejima K, Allison DB, Evans DT, Rakasz EG, Parks CL, Bonaldo MC, Capuano S, Lifson JD, Desrosiers RC, Allen TM, Watkins DI. Mamu-B*17+ Rhesus Macaques Vaccinated with env, vif, and nef Manifest Early Control of SIVmac239 Replication. J Virol. 2018 08 15; 92(16). PMID: 29875239.
      Citations: 7     Fields:    Translation:AnimalsCells
    31. Magnani DM, Rogers TF, Maness NJ, Grubaugh ND, Beutler N, Bailey VK, Gonzalez-Nieto L, Gutman MJ, Pedre?o-Lopez N, Kwal JM, Ricciardi MJ, Myers TA, Julander JG, Bohm RP, Gilbert MH, Schiro F, Aye PP, Blair RV, Martins MA, Falkenstein KP, Kaur A, Curry CL, Kallas EG, Desrosiers RC, Goldschmidt-Clermont PJ, Whitehead SS, Andersen KG, Bonaldo MC, Lackner AA, Panganiban AT, Burton DR, Watkins DI. Fetal demise and failed antibody therapy during Zika virus infection of pregnant macaques. Nat Commun. 2018 04 24; 9(1):1624. PMID: 29691387.
      Citations: 47     Fields:    Translation:HumansAnimalsCells
    32. Mavigner M, Raper J, Kovacs-Balint Z, Gumber S, O'Neal JT, Bhaumik SK, Zhang X, Habib J, Mattingly C, McDonald CE, Avanzato V, Burke MW, Magnani DM, Bailey VK, Watkins DI, Vanderford TH, Fair D, Earl E, Feczko E, Styner M, Jean SM, Cohen JK, Silvestri G, Johnson RP, O'Connor DH, Wrammert J, Suthar MS, Sanchez MM, Alvarado MC, Chahroudi A. Postnatal Zika virus infection is associated with persistent abnormalities in brain structure, function, and behavior in infant macaques. Sci Transl Med. 2018 04 04; 10(435). PMID: 29618564.
      Citations: 41     Fields:    Translation:Animals
    33. Ricciardi MJ, Magnani DM, Grifoni A, Kwon YC, Gutman MJ, Grubaugh ND, Gangavarapu K, Sharkey M, Silveira CGT, Bailey VK, Pedre?o-Lopez N, Gonzalez-Nieto L, Maxwell HS, Domingues A, Martins MA, Pham J, Weiskopf D, Altman J, Kallas EG, Andersen KG, Stevenson M, Lichtenberger P, Choe H, Whitehead SS, Sette A, Watkins DI. Ontogeny of the B- and T-cell response in a primary Zika virus infection of a dengue-na?ve individual during the 2016 outbreak in Miami, FL. PLoS Negl Trop Dis. 2017 12; 11(12):e0006000. PMID: 29267278.
      Citations: 31     Fields:    Translation:HumansCellsPHPublic Health
    34. Grifoni A, Pham J, Sidney J, O'Rourke PH, Paul S, Peters B, Martini SR, de Silva AD, Ricciardi MJ, Magnani DM, Silveira CGT, Maestri A, Costa PR, de-Oliveira-Pinto LM, de Azeredo EL, Damasco PV, Phillips E, Mallal S, de Silva AM, Collins M, Durbin A, Diehl SA, Cerpas C, Balmaseda A, Kuan G, Coloma J, Harris E, Crowe JE, Stone M, Norris PJ, Busch M, Vivanco-Cid H, Cox J, Graham BS, Ledgerwood JE, Turtle L, Solomon T, Kallas EG, Watkins DI, Weiskopf D, Sette A. Prior Dengue Virus Exposure Shapes T Cell Immunity to Zika Virus in Humans. J Virol. 2017 12 15; 91(24). PMID: 28978707.
      Citations: 107     Fields:    Translation:HumansCells
    35. Magnani DM, Silveira CGT, Ricciardi MJ, Gonzalez-Nieto L, Pedre?o-Lopez N, Bailey VK, Gutman MJ, Maxwell HS, Domingues A, Costa PR, Ferrari L, Goulart R, Martins MA, Martinez-Navio JM, Fuchs SP, Kalil J, Timenetsky MDC, Wrammert J, Whitehead SS, Burton DR, Desrosiers RC, Kallas EG, Watkins DI. Potent Plasmablast-Derived Antibodies Elicited by the National Institutes of Health Dengue Vaccine. J Virol. 2017 11 15; 91(22). PMID: 28878078.
      Citations: 12     Fields:    Translation:HumansCellsCTClinical Trials
    36. Magnani DM, Rogers TF, Beutler N, Ricciardi MJ, Bailey VK, Gonzalez-Nieto L, Briney B, Sok D, Le K, Strubel A, Gutman MJ, Pedre?o-Lopez N, Grubaugh ND, Silveira CGT, Maxwell HS, Domingues A, Martins MA, Lee DE, Okwuazi EE, Jean S, Strobert EA, Chahroudi A, Silvestri G, Vanderford TH, Kallas EG, Desrosiers RC, Bonaldo MC, Whitehead SS, Burton DR, Watkins DI. Neutralizing human monoclonal antibodies prevent Zika virus infection in macaques. Sci Transl Med. 2017 Oct 04; 9(410). PMID: 28978754.
      Citations: 53     Fields:    Translation:HumansAnimals
    37. Termini JM, Magnani DM, Maxwell HS, Lauer W, Castro I, Pecotte J, Barber GN, Watkins DI, Desrosiers RC. Simian T Lymphotropic Virus 1 Infection of Papio anubis: tax Sequence Heterogeneity and T Cell Recognition. J Virol. 2017 10 15; 91(20). PMID: 28724769.
      Citations: 3     Fields:    Translation:AnimalsCells
    38. Bischof GF, Magnani DM, Ricciardi M, Shin YC, Domingues A, Bailey VK, Gonzalez-Nieto L, Rakasz EG, Watkins DI, Desrosiers RC. Use of a Recombinant Gamma-2 Herpesvirus Vaccine Vector against Dengue Virus in Rhesus Monkeys. J Virol. 2017 08 15; 91(16). PMID: 28592531.
      Citations: 3     Fields:    Translation:AnimalsCells
    39. Magnani DM, Ricciardi MJ, Bailey VK, Gutman MJ, Pedre?o-Lopez N, Silveira CGT, Maxwell HS, Domingues A, Gonzalez-Nieto L, Su Q, Newman RM, Pack M, Martins MA, Martinez-Navio JM, Fuchs SP, Rakasz EG, Allen TM, Whitehead SS, Burton DR, Gao G, Desrosiers RC, Kallas EG, Watkins DI. Dengue Virus Evades AAV-Mediated Neutralizing Antibody Prophylaxis in Rhesus Monkeys. Mol Ther. 2017 10 04; 25(10):2323-2331. PMID: 28750738.
      Citations: 8     Fields:    Translation:AnimalsCells
    40. Martins MA, Shin YC, Gonzalez-Nieto L, Domingues A, Gutman MJ, Maxwell HS, Castro I, Magnani DM, Ricciardi M, Pedre?o-Lopez N, Bailey V, Betancourt D, Altman JD, Pauthner M, Burton DR, von Bredow B, Evans DT, Yuan M, Parks CL, Ejima K, Allison DB, Rakasz E, Barber GN, Capuano S, Lifson JD, Desrosiers RC, Watkins DI. Vaccine-induced immune responses against both Gag and Env improve control of simian immunodeficiency virus replication in rectally challenged rhesus macaques. PLoS Pathog. 2017 Jul; 13(7):e1006529. PMID: 28732035.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    41. Martins MA, Tully DC, Shin YC, Gonzalez-Nieto L, Weisgrau KL, Bean DJ, Gadgil R, Gutman MJ, Domingues A, Maxwell HS, Magnani DM, Ricciardi M, Pedre?o-Lopez N, Bailey V, Cruz MA, Lima NS, Bonaldo MC, Altman JD, Rakasz E, Capuano S, Reimann KA, Piatak M, Lifson JD, Desrosiers RC, Allen TM, Watkins DI. Rare Control of SIVmac239 Infection in a Vaccinated Rhesus Macaque. AIDS Res Hum Retroviruses. 2017 08; 33(8):843-858. PMID: 28503929.
      Citations: 12     Fields:    Translation:AnimalsCells
    42. Magnani DM, Silveira CGT, Rosen BC, Ricciardi MJ, Pedre?o-Lopez N, Gutman MJ, Bailey VK, Maxwell HS, Domingues A, Gonzalez-Nieto L, Avelino-Silva VI, Trindade M, Nogueira J, Oliveira CS, Maestri A, Felix AC, Levi JE, Nogueira ML, Martins MA, Martinez-Navio JM, Fuchs SP, Whitehead SS, Burton DR, Desrosiers RC, Kallas EG, Watkins DI. A human inferred germline antibody binds to an immunodominant epitope and neutralizes Zika virus. PLoS Negl Trop Dis. 2017 Jun; 11(6):e0005655. PMID: 28604797.
      Citations: 14     Fields:    Translation:HumansCells
    43. Aliota MT, Bassit L, Bradrick SS, Cox B, Garcia-Blanco MA, Gavegnano C, Friedrich TC, Golos TG, Griffin DE, Haddow AD, Kallas EG, Kitron U, Lecuit M, Magnani DM, Marrs C, Mercer N, McSweegan E, Ng LFP, O'Connor DH, Osorio JE, Ribeiro GS, Ricciardi M, Rossi SL, Saade G, Schinazi RF, Schott-Lerner GO, Shan C, Shi PY, Watkins DI, Vasilakis N, Weaver SC. Zika in the Americas, year 2: What have we learned? What gaps remain? A report from the Global Virus Network. Antiviral Res. 2017 08; 144:223-246. PMID: 28595824.
      Citations: 59     Fields:    Translation:AnimalsPHPublic Health
    44. Grubaugh ND, Ladner JT, Kraemer MUG, Dudas G, Tan AL, Gangavarapu K, Wiley MR, White S, Th?z? J, Magnani DM, Prieto K, Reyes D, Bingham AM, Paul LM, Robles-Sikisaka R, Oliveira G, Pronty D, Barcellona CM, Metsky HC, Baniecki ML, Barnes KG, Chak B, Freije CA, Gladden-Young A, Gnirke A, Luo C, MacInnis B, Matranga CB, Park DJ, Qu J, Schaffner SF, Tomkins-Tinch C, West KL, Winnicki SM, Wohl S, Yozwiak NL, Quick J, Fauver JR, Khan K, Brent SE, Reiner RC, Lichtenberger PN, Ricciardi MJ, Bailey VK, Watkins DI, Cone MR, Kopp EW, Hogan KN, Cannons AC, Jean R, Monaghan AJ, Garry RF, Loman NJ, Faria NR, Porcelli MC, Vasquez C, Nagle ER, Cummings DAT, Stanek D, Rambaut A, Sanchez-Lockhart M, Sabeti PC, Gillis LD, Michael SF, Bedford T, Pybus OG, Isern S, Palacios G, Andersen KG. Genomic epidemiology reveals multiple introductions of Zika virus into the United States. Nature. 2017 06 15; 546(7658):401-405. PMID: 28538723.
      Citations: 162     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    45. Gonzalez-Nieto L, Domingues A, Ricciardi M, Gutman MJ, Maxwell HS, Pedre?o-Lopez N, Bailey V, Magnani DM, Martins MA. Analysis of Simian Immunodeficiency Virus-specific CD8+ T-cells in Rhesus Macaques by Peptide-MHC-I Tetramer Staining. J Vis Exp. 2016 12 23; (118). PMID: 28060314.
      Citations:    
    46. Castro I, Giret TM, Magnani DM, Maxwell HS, Umland O, Perry JK, Pecotte JK, Brasky KM, Barber GN, Desrosiers RC, Watkins DI. Cellular Immune Responses against Simian T-Lymphotropic Virus Type 1 Target Tax in Infected Baboons. J Virol. 2016 06 01; 90(11):5280-5291. PMID: 26984729.
      Citations:    
    47. Martins MA, Tully DC, Cruz MA, Power KA, Veloso de Santana MG, Bean DJ, Ogilvie CB, Gadgil R, Lima NS, Magnani DM, Ejima K, Allison DB, Piatak M, Altman JD, Parks CL, Rakasz EG, Capuano S, Galler R, Bonaldo MC, Lifson JD, Allen TM, Watkins DI. Vaccine-Induced Simian Immunodeficiency Virus-Specific CD8+ T-Cell Responses Focused on a Single Nef Epitope Select for Escape Variants Shortly after Infection. J Virol. 2015 Nov; 89(21):10802-20. PMID: 26292326.
      Citations:    
    48. Splitter G, Harms J, Petersen E, Magnani D, Durward M, Rajashekara G, Radhakrishnan G. Studying host-pathogen interaction events in living mice visualized in real time using biophotonic imaging. Methods Mol Biol. 2014; 1197:67-85. PMID: 25172275.
      Citations:    
    49. Smith JA, Khan M, Magnani DD, Harms JS, Durward M, Radhakrishnan GK, Liu YP, Splitter GA. Brucella induces an unfolded protein response via TcpB that supports intracellular replication in macrophages. PLoS Pathog. 2013; 9(12):e1003785. PMID: 24339776.
      Citations: 73     Fields:    Translation:AnimalsCells
    50. Magnani DM, Lyons ET, Forde TS, Shekhani MT, Adarichev VA, Splitter GA. Osteoarticular tissue infection and development of skeletal pathology in murine brucellosis. Dis Model Mech. 2013 May; 6(3):811-8. PMID: 23519029.
      Citations:    
    51. Durward M, Radhakrishnan G, Harms J, Bareiss C, Magnani D, Splitter GA. Active evasion of CTL mediated killing and low quality responding CD8+ T cells contribute to persistence of brucellosis. PLoS One. 2012; 7(4):e34925. PMID: 22558103.
      Citations:    
    52. Durward MA, Harms J, Magnani DM, Eskra L, Splitter GA. Discordant Brucella melitensis antigens yield cognate CD8+ T cells in vivo. Infect Immun. 2010 Jan; 78(1):168-76. PMID: 19884330.
      Citations:    
    53. Harms JS, Durward MA, Magnani DM, Splitter GA. Evaluation of recombinant invasive, non-pathogenic Eschericia coli as a vaccine vector against the intracellular pathogen, Brucella. J Immune Based Ther Vaccines. 2009 Jan 06; 7:1. PMID: 19126207.
      Citations:    
    54. Macedo GC, Magnani DM, Carvalho NB, Bruna-Romero O, Gazzinelli RT, Oliveira SC. Central role of MyD88-dependent dendritic cell maturation and proinflammatory cytokine production to control Brucella abortus infection. J Immunol. 2008 Jan 15; 180(2):1080-7. PMID: 18178848.
      Citations:    
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