Edward Kelly to Animals
This is a "connection" page, showing publications Edward Kelly has written about Animals.
Connection Strength
0.627
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Hsu EW, Wang K, Tsang YP, Himmelfarb J, Yeung CK, Kelly EJ. Potential integration of multiple organs-on-a-chip for comprehensive drug-drug interaction prediction. Expert Opin Drug Metab Toxicol. 2026 Jan-Feb; 22(2):83-103.
Score: 0.066
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Hansen BC, Aryeh KS, Lindell LX, Lau GK, Nicholson TM, Faustman EM, Kelly EJ. In vitro models of the male reproductive system: applications for developmental and reproductive toxicology. Toxicol Sci. 2025 12 01; 208(2):188-206.
Score: 0.065
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Hansen BC, Arian CM, Zeng Y, Takezawa MG, Theberge AB, Faustman EM, Thummel KE, Kelly EJ. Leveraging RNA-seq deconvolution to improve complex in vitro model characterization. J Biol Chem. 2025 09; 301(9):110510.
Score: 0.063
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Tsang YP, Aryeh KS, Wang K, Himmelfarb J, Yeung CK, Kelly EJ. Enhancing therapeutic strategies and drug development for patients with kidney disease. Expert Opin Drug Saf. 2026 Jan; 25(1):23-48.
Score: 0.063
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O'Mahony ET, Arian CM, Aryeh KS, Wang K, Thummel KE, Kelly EJ. Human intestinal enteroids: Nonclinical applications for predicting oral drug disposition, toxicity, and efficacy. Pharmacol Ther. 2025 09; 273:108879.
Score: 0.063
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Kelly EJ, Ziedins EE, Carney BC, Moffatt LT, Shupp JW. Endothelial dysfunction is dampened by early administration of fresh frozen plasma in a rodent burn shock model. J Trauma Acute Care Surg. 2024 10 01; 97(4):520-528.
Score: 0.059
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Weber EJ, Lidberg KA, Wang L, Bammler TK, MacDonald JW, Li MJ, Redhair M, Atkins WM, Tran C, Hines KM, Herron J, Xu L, Monteiro MB, Ramm S, Vaidya V, Vaara M, Vaara T, Himmelfarb J, Kelly EJ. Human kidney on a chip assessment of polymyxin antibiotic nephrotoxicity. JCI Insight. 2018 12 20; 3(24).
Score: 0.040
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Lockhart CM, Nakano M, Rettie AE, Kelly EJ. Generation and characterization of a murine model of Bietti crystalline dystrophy. Invest Ophthalmol Vis Sci. 2014 Aug 12; 55(9):5572-81.
Score: 0.030
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Kelly EJ, Nakano M, Rohatgi P, Yarov-Yarovoy V, Rettie AE. Finding homes for orphan cytochrome P450s: CYP4V2 and CYP4F22 in disease states. Mol Interv. 2011 Apr; 11(2):124-32.
Score: 0.024
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Kelly E, Mathew J, Kohler JE, Blass AL, Soybel DI. Redistribution of labile plasma zinc during mild surgical stress in the rat. Transl Res. 2011 Mar; 157(3):139-49.
Score: 0.023
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Sun A, Hagenbuch B, Kelly EJ, Wang J. Molecular Mechanisms of Organic Anion Transporting Polypeptide-Mediated Organic Anion Clearance at the Blood-Cerebrospinal Fluid Barrier. Mol Pharmacol. 2023 12; 104(6):255-265.
Score: 0.014
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Lidberg KA, Muthusamy S, Adil M, Mahadeo A, Yang J, Patel RS, Wang L, Bammler TK, Reichel J, Yeung CK, Himmelfarb J, Kelly EJ, Akilesh S. Serum Protein Exposure Activates a Core Regulatory Program Driving Human Proximal Tubule Injury. J Am Soc Nephrol. 2022 05; 33(5):949-965.
Score: 0.013
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Kowalski JP, Pelletier RD, McDonald MG, Kelly EJ, Rettie AE. Pharmacokinetics, metabolism and off-target effects in the rat of 8-[(1H- benzotriazol-1-yl)amino]octanoic acid, a selective inhibitor of human cytochrome P450 4Z1: ?-oxidation as a potential augmenting pathway for inhibition. Xenobiotica. 2021 Aug; 51(8):901-915.
Score: 0.012
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Rayner SG, Phong KT, Xue J, Lih D, Shankland SJ, Kelly EJ, Himmelfarb J, Zheng Y. Reconstructing the Human Renal Vascular-Tubular Unit In Vitro. Adv Healthc Mater. 2018 12; 7(23):e1801120.
Score: 0.010
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Bajaj P, Chowdhury SK, Yucha R, Kelly EJ, Xiao G. Emerging Kidney Models to Investigate Metabolism, Transport, and Toxicity of Drugs and Xenobiotics. Drug Metab Dispos. 2018 11; 46(11):1692-1702.
Score: 0.010
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Chapron BD, Chapron A, Phillips B, Okoli MC, Shen DD, Kelly EJ, Himmelfarb J, Thummel KE. Reevaluating the role of megalin in renal vitamin D homeostasis using a human cell-derived microphysiological system ALTEX. 2018; 35(4):504-515.
Score: 0.010
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Chang SY, Weber EJ, Sidorenko VS, Chapron A, Yeung CK, Gao C, Mao Q, Shen D, Wang J, Rosenquist TA, Dickman KG, Neumann T, Grollman AP, Kelly EJ, Himmelfarb J, Eaton DL. Human liver-kidney model elucidates the mechanisms of aristolochic acid nephrotoxicity. JCI Insight. 2017 11 16; 2(22).
Score: 0.009
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Chang SY, Voellinger JL, Van Ness KP, Chapron B, Shaffer RM, Neumann T, White CC, Kavanagh TJ, Kelly EJ, Eaton DL. Characterization of rat or human hepatocytes cultured in microphysiological systems (MPS) to identify hepatotoxicity. Toxicol In Vitro. 2017 Apr; 40:170-183.
Score: 0.009
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Parkinson OT, Teitelbaum AM, Whittington D, Kelly EJ, Rettie AE. Species Differences in Microsomal Oxidation and Glucuronidation of 4-Ipomeanol: Relationship to Target Organ Toxicity. Drug Metab Dispos. 2016 10; 44(10):1598-602.
Score: 0.009
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Wiek C, Schmidt EM, Roellecke K, Freund M, Nakano M, Kelly EJ, Kaisers W, Yarov-Yarovoy V, Kramm CM, Rettie AE, Hanenberg H. Identification of amino acid determinants in CYP4B1 for optimal catalytic processing of 4-ipomeanol. Biochem J. 2015 Jan 01; 465(1):103-14.
Score: 0.008
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Lee N, Hebert MF, Prasad B, Easterling TR, Kelly EJ, Unadkat JD, Wang J. Effect of gestational age on mRNA and protein expression of polyspecific organic cation transporters during pregnancy. Drug Metab Dispos. 2013 Dec; 41(12):2225-32.
Score: 0.007
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Topletz AR, Le HN, Lee N, Chapman JD, Kelly EJ, Wang J, Isoherranen N. Hepatic Cyp2d and Cyp26a1 mRNAs and activities are increased during mouse pregnancy. Drug Metab Dispos. 2013 Feb; 41(2):312-9.
Score: 0.007
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Crouthamel MH, Kelly EJ, Ho RJ. Development and characterization of transgenic mouse models for conditional gene knockout in the blood-brain and blood-CSF barriers. Transgenic Res. 2012 Feb; 21(1):113-30.
Score: 0.006
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Nakano M, Kelly EJ, Rettie AE. Expression and characterization of CYP4V2 as a fatty acid omega-hydroxylase. Drug Metab Dispos. 2009 Nov; 37(11):2119-22.
Score: 0.005
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Salama NN, Kelly EJ, Bui T, Ho RJ. The impact of pharmacologic and genetic knockout of P-glycoprotein on nelfinavir levels in the brain and other tissues in mice. J Pharm Sci. 2005 Jun; 94(6):1216-25.
Score: 0.004