Myeloid-Derived Suppressor Cells

"Myeloid-Derived Suppressor Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A heterogeneous, immature population of myeloid cells that can suppress the activity of T-CELLS and NATURAL KILLER CELLS in the INNATE IMMUNE RESPONSE and ADAPTIVE IMMUNE RESPONSE. They play important roles in ONCOGENESIS; INFLAMMATION; and INFECTION.

Descriptor ID	D000072737
MeSH Number(s)	A11.627.817
Concept/Terms	Myeloid-Derived Suppressor Cells Myeloid-Derived Suppressor Cells Cell, Myeloid-Derived Suppressor Cells, Myeloid-Derived Suppressor Myeloid Derived Suppressor Cells Myeloid-Derived Suppressor Cell Suppressor Cell, Myeloid-Derived Suppressor Cells, Myeloid-Derived MDSCs

Below are MeSH descriptors whose meaning is more general than "Myeloid-Derived Suppressor Cells".

Anatomy [A]
Cells [A11]
Myeloid Cells [A11.627]
Myeloid-Derived Suppressor Cells [A11.627.817]

Below are MeSH descriptors whose meaning is related to "Myeloid-Derived Suppressor Cells".

Below are MeSH descriptors whose meaning is more specific than "Myeloid-Derived Suppressor Cells".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Myeloid-Derived Suppressor Cells" by people in this website by year, and whether "Myeloid-Derived Suppressor Cells" was a major or minor topic of these publications.

Bar chart showing 6 publications over 5 distinct years, with a maximum of 2 publications in 2018

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2016	1	0	1
2017	1	0	1
2018	0	2	2
2019	0	1	1
2020	1	0	1

Below are the most recent publications written about "Myeloid-Derived Suppressor Cells" by people in Profiles.

Cai S, Choi JY, Borges TJ, Zhang H, Miao J, Ichimura T, Li X, Xu S, Chu P, Eskandari SK, Allos H, Alhaddad JB, Muhsin SA, Yatim K, Riella LV, Sage PT, Chandraker AK, Azzi JR. Donor myeloid derived suppressor cells (MDSCs) prolong allogeneic cardiac graft survival through programming of recipient myeloid cells in vivo. Sci Rep. 2020 08 28; 10(1):14249.

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Singel KL, Emmons TR, Khan ANH, Mayor PC, Shen S, Wong JT, Morrell K, Eng KH, Mark J, Bankert RB, Matsuzaki J, Koya RC, Blom AM, McLeish KR, Qu J, Ram S, Moysich KB, Abrams SI, Odunsi K, Zsiros E, Segal BH. Mature neutrophils suppress T cell immunity in ovarian cancer microenvironment. JCI Insight. 2019 03 07; 4(5).

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van de Donk NWCJ, Usmani SZ. CD38 Antibodies in Multiple Myeloma: Mechanisms of Action and Modes of Resistance. Front Immunol. 2018; 9:2134.

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Hossain F, Majumder S, Ucar DA, Rodriguez PC, Golde TE, Minter LM, Osborne BA, Miele L. Notch Signaling in Myeloid Cells as a Regulator of Tumor Immune Responses. Front Immunol. 2018; 9:1288.

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Sierra RA, Trillo-Tinoco J, Mohamed E, Yu L, Achyut BR, Arbab A, Bradford JW, Osborne BA, Miele L, Rodriguez PC. Anti-Jagged Immunotherapy Inhibits MDSCs and Overcomes Tumor-Induced Tolerance. Cancer Res. 2017 10 15; 77(20):5628-5638.

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Chiu DK, Tse AP, Xu IM, Di Cui J, Lai RK, Li LL, Koh HY, Tsang FH, Wei LL, Wong CM, Ng IO, Wong CC. Hypoxia inducible factor HIF-1 promotes myeloid-derived suppressor cells accumulation through ENTPD2/CD39L1 in hepatocellular carcinoma. Nat Commun. 2017 09 11; 8(1):517.

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Chiu DK, Xu IM, Lai RK, Tse AP, Wei LL, Koh HY, Li LL, Lee D, Lo RC, Wong CM, Ng IO, Wong CC. Hypoxia induces myeloid-derived suppressor cell recruitment to hepatocellular carcinoma through chemokine (C-C motif) ligand 26. Hepatology. 2016 09; 64(3):797-813.

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Otvos B, Silver DJ, Mulkearns-Hubert EE, Alvarado AG, Turaga SM, Sorensen MD, Rayman P, Flavahan WA, Hale JS, Stoltz K, Sinyuk M, Wu Q, Jarrar A, Kim SH, Fox PL, Nakano I, Rich JN, Ransohoff RM, Finke J, Kristensen BW, Vogelbaum MA, Lathia JD. Cancer Stem Cell-Secreted Macrophage Migration Inhibitory Factor Stimulates Myeloid Derived Suppressor Cell Function and Facilitates Glioblastoma Immune Evasion. Stem Cells. 2016 08; 34(8):2026-39.

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