Purinergic P2X Receptor Antagonists
"Purinergic P2X Receptor Antagonists" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Compounds that bind to and block the stimulation of PURINERGIC P2X RECEPTORS. Included under this heading are antagonists for specific P2X receptor subtypes.
| Descriptor ID |
D058920
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| MeSH Number(s) |
D27.505.519.625.725.400.200.100 D27.505.696.577.725.400.200.100
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Purinergic P2X Receptor Antagonists".
Below are MeSH descriptors whose meaning is more specific than "Purinergic P2X Receptor Antagonists".
This graph shows the total number of publications written about "Purinergic P2X Receptor Antagonists" by people in this website by year, and whether "Purinergic P2X Receptor Antagonists" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
| 2020 | 2 | 0 | 2 |
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Below are the most recent publications written about "Purinergic P2X Receptor Antagonists" by people in Profiles.
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Soare AY, Malik HS, Durham ND, Freeman TL, Alvarez R, Patel F, Satija N, Upadhyay C, Hioe CE, Chen BK, Swartz TH. P2X1 Selective Antagonists Block HIV-1 Infection through Inhibition of Envelope Conformation-Dependent Fusion. J Virol. 2020 02 28; 94(6).
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Irwin RS, French CL, Madison JM. Managing unexplained chronic cough in adults: what are the unmet needs? Lancet Respir Med. 2020 08; 8(8):745-747.
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Soare AY, Durham ND, Gopal R, Tweel B, Hoffman KW, Brown JA, O'Brien M, Bhardwaj N, Lim JK, Chen BK, Swartz TH. P2X Antagonists Inhibit HIV-1 Productive Infection and Inflammatory Cytokines Interleukin-10 (IL-10) and IL-1? in a Human Tonsil Explant Model. J Virol. 2019 01 01; 93(1).
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Yanachkov IB, Chang H, Yanachkova MI, Dix EJ, Berny-Lang MA, Gremmel T, Michelson AD, Wright GE, Frelinger AL. New highly active antiplatelet agents with dual specificity for platelet P2Y1 and P2Y12 adenosine diphosphate receptors. Eur J Med Chem. 2016 Jan 01; 107:204-18.
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Cuadra AE, Custer EE, Bosworth EL, Lemos JR. P2X7 receptors in neurohypophysial terminals: evidence for their role in arginine-vasopressin secretion. J Cell Physiol. 2014 Mar; 229(3):333-42.
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Akbari SH, Reynolds MR, Kadkhodayan Y, Cross DT, Moran CJ. Hemorrhagic complications after prasugrel (Effient) therapy for vascular neurointerventional procedures. J Neurointerv Surg. 2013 Jul; 5(4):337-43.
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Custer EE, Knott TK, Cuadra AE, Ortiz-Miranda S, Lemos JR. P2X purinergic receptor knockout mice reveal endogenous ATP modulation of both vasopressin and oxytocin release from the intact neurohypophysis. J Neuroendocrinol. 2012 Apr; 24(4):674-80.
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Knott TK, Hussy N, Cuadra AE, Lee RH, Ortiz-Miranda S, Custer EE, Lemos JR. Adenosine trisphosphate appears to act via different receptors in terminals versus somata of the hypothalamic neurohypophysial system. J Neuroendocrinol. 2012 Apr; 24(4):681-9.
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Casati A, Frascoli M, Traggiai E, Proietti M, Schenk U, Grassi F. Cell-autonomous regulation of hematopoietic stem cell cycling activity by ATP. Cell Death Differ. 2011 Mar; 18(3):396-404.