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Behroze Adi Vachha MD, PhD

TitleAssociate Professor
InstitutionUMass Chan Medical School
DepartmentRadiology
AddressUMass Chan Medical School
55 Lake Avenue North
Worcester MA 01655
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    Other Positions
    InstitutionT.H. Chan School of Medicine
    DepartmentRadiology
    DivisionNeuroradiology


    Collapse Biography 
    Collapse education and training
    B.J. Medical College, Ahmedabad, GJ, IndiaMBBS
    University of Texas, Dallas, Dallas, TX, United StatesPHDHuman Development

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Kolstad J, Zoppo C, Johnston JM, D'Souza P, K?hn AL, Vardar Z, Peker A, Hader A, Celik H, Lewis CJ, Lindsay C, Rentiya ZS, Lebel C, Vedantham S, Vachha B, Gray-Edwards HL, Acosta MT, Tifft CJ, Shazeeb MS. Natural history progression of MRI brain volumetrics in type II late-infantile and juvenile GM1 gangliosidosis patients. Mol Genet Metab. 2025 Jan 19; 144(3):109025. PMID: 39874851.
      Citations:    
    2. Vachha BA, Kumar VA, Pillai JJ, Shimony J, Tanabe J, Sair HI. Resting-State Functional MRI: Current State, Controversies, Limitations, and Future Directions-AJR Expert Panel Narrative Review. AJR Am J Roentgenol. 2024 Dec 11. PMID: 39660823.
      Citations:    
    3. Daci R, Gray-Edwards H, Shazeeb MS, Vardar Z, Vachha B, Cataltepe OI, Flotte TR. Neuroimaging Applications for the Delivery and Monitoring of Gene Therapy for Central Nervous System Diseases. Hum Gene Ther. 2024 Nov; 35(21-22):886-895. PMID: 39323316.
      Citations:    
    4. Tringale KR, Scordo M, Yahalom J, White C, Zhang Z, Vachha B, Cederquist G, Schaff L, DeAngelis L, Grommes C, Imber BS. Outcomes and relapse patterns in primary central nervous system lymphoma: Longitudinal analysis of 559 patients diagnosed from 1983 to 2020. Neuro Oncol. 2024 Nov 04; 26(11):2061-2073. PMID: 38915246.
      Citations:    
    5. Zoppo C, Kolstad J, Johnston J, D'Souza P, K?hn AL, Vardar Z, Peker A, Lindsay C, Rentiya ZS, King R, Gray-Edwards H, Vachha B, Acosta MT, Tifft CJ, Shazeeb MS. Quantitative reliability assessment of brain MRI volumetric measurements in type II GM1 gangliosidosis patients. Front Neuroimaging. 2024; 3:1410848. PMID: 39350771.
      Citations:    
    6. Kumar VA, Lee J, Liu HL, Allen JW, Filippi CG, Holodny AI, Hsu K, Jain R, McAndrews MP, Peck KK, Shah G, Shimony JS, Singh S, Zeineh M, Tanabe J, Vachha B, Vossough A, Welker K, Whitlow C, Wintermark M, Zaharchuk G, Sair HI. Recommended Resting-State fMRI Acquisition and Preprocessing Steps for Preoperative Mapping of Language and Motor and Visual Areas in Adult and Pediatric Patients with Brain Tumors and Epilepsy. AJNR Am J Neuroradiol. 2024 02 07; 45(2):139-148. PMID: 38164572.
      Citations:    Fields:    Translation:Humans
    7. Correa DD, Vachha BA, Baser RE, Koch A, Wong P, Gohel S, Giralt S, Root JC. Neuroimaging and Neurocognitive Outcomes in Older Patients with Multiple Myeloma Treated with Chemotherapy and Autologous Stem Cell Transplantation. Cancers (Basel). 2023 Sep 08; 15(18). PMID: 37760454.
      Citations:    
    8. Tringale KR, Gangai N, Chua A, Godwin K, Guman G, Laufer I, Cathcart KNS, Lis E, Schmitt A, Moskowitz CS, Chilov M, Vachha BA. Spine MRI Identifies Clinically Relevant Findings in Patients With Cancer Presenting With Back Pain. Spine (Phila Pa 1976). 2024 Mar 15; 49(6):419-425. PMID: 37602415.
      Citations:    Fields:    
    9. Correa DD, Vachha BA, Baser RE, Koch A, Wong P, Gohel S, Giralt S, Root JC. Neuroimaging and Neurocognitive Outcomes in Older Patients with Multiple Myeloma Treated with Chemotherapy and Autologous Stem Cell Transplantation. Res Sq. 2023 Apr 05. PMID: 37066224.
      Citations:    
    10. Vachha BA, Massoud TF, Huang SY. Anatomy of the Cerebral Cortex, Lobes, and Cerebellum. Neuroimaging Clin N Am. 2022 Aug; 32(3):463-473. PMID: 35843656.
      Citations: 1     Fields:    Translation:Humans
    11. Vachha BA, Middlebrooks EH. Brain Functional Imaging Anatomy. Neuroimaging Clin N Am. 2022 Aug; 32(3):491-505. PMID: 35843658.
      Citations:    Fields:    Translation:Humans
    12. Vachha BA, Huang RY. BOLD asynchrony: An imaging biomarker of tumor burden in IDH-mutated gliomas. Neuro Oncol. 2022 01 05; 24(1):88-89. PMID: 34695182.
      Citations:    Fields:    Translation:Humans
    13. Vachha B, Huang SY. MRI with ultrahigh field strength and high-performance gradients: challenges and opportunities for clinical neuroimaging at 7 T and beyond. Eur Radiol Exp. 2021 08 26; 5(1):35. PMID: 34435246.
      Citations: 15     Fields:    
    14. Vachha BA, Gohel S, Root JC, Kryza-Lacombe M, Hensley ML, Correa DD. Altered regional homogeneity in patients with ovarian cancer treated with chemotherapy: a resting state fMRI study. Brain Imaging Behav. 2022 Apr; 16(2):539-546. PMID: 34409561.
      Citations: 4     Fields:    Translation:Humans
    15. Vachha BA, Huang SY, Massoud TF. Editorial: Advanced Neuroimaging of Brain Metastases. Front Neurol. 2021; 12:668310. PMID: 33815266.
      Citations:    
    16. Remsik J, Wilcox JA, Babady NE, McMillen TA, Vachha BA, Halpern NA, Dhawan V, Rosenblum M, Iacobuzio-Donahue CA, Avila EK, Santomasso B, Boire A. Inflammatory Leptomeningeal Cytokines Mediate COVID-19 Neurologic Symptoms in Cancer Patients. Cancer Cell. 2021 02 08; 39(2):276-283.e3. PMID: 33508216.
      Citations: 29     Fields:    Translation:Humans
    17. Yang J, Gohel S, Zhang Z, Hatzoglou V, Holodny AI, Vachha BA. Glioma-Induced Disruption of Resting-State Functional Connectivity and Amplitude of Low-Frequency Fluctuations in the Salience Network. AJNR Am J Neuroradiol. 2021 03; 42(3):551-558. PMID: 33384293.
      Citations: 8     Fields:    Translation:Humans
    18. Shah AD, Shridhar Konar A, Paudyal R, Oh JH, LoCastro E, Nu?ez DA, Swinburne N, Vachha B, Ulaner GA, Young RJ, Holodny AI, Beal K, Shukla-Dave A, Hatzoglou V. Diffusion and Perfusion MRI Predicts Response Preceding and Shortly After Radiosurgery to Brain Metastases: A Pilot Study. J Neuroimaging. 2021 03; 31(2):317-323. PMID: 33370467.
      Citations: 7     Fields:    Translation:Humans
    19. Remsik J, Wilcox JA, Babady NE, McMillen T, Vachha BA, Halpern NA, Dhawan V, Rosenblum M, Iacobuzio-Donahue CA, Avila EK, Santomasso B, Boire A. Inflammatory leptomeningeal cytokines mediate delayed COVID-19 encephalopathy. medRxiv. 2020 Sep 18. PMID: 32995805.
      Citations:    
    20. Swinburne N, LoCastro E, Paudyal R, Oh JH, Taunk NK, Shah A, Beal K, Vachha B, Young RJ, Holodny AI, Shukla-Dave A, Hatzoglou V. Computational Modeling of Interstitial Fluid Pressure and Velocity in Non-small Cell Lung Cancer Brain Metastases Treated With Stereotactic Radiosurgery. Front Neurol. 2020; 11:402. PMID: 32547470.
      Citations:    
    21. Yang J, Gohel S, Vachha B. Current methods and new directions in resting state fMRI. Clin Imaging. 2020 Sep; 65:47-53. PMID: 32353718.
      Citations: 31     Fields:    Translation:Humans
    22. Sun H, Vachha B, Laino ME, Jenabi M, Flynn JR, Zhang Z, Holodny AI, Peck KK. Decreased Hand Motor Resting-State Functional Connectivity in Patients with Glioma: Analysis of Factors including Neurovascular Uncoupling. Radiology. 2020 03; 294(3):610-621. PMID: 31934827.
      Citations: 9     Fields:    Translation:Humans
    23. Gohel S, Laino ME, Rajeev-Kumar G, Jenabi M, Peck K, Hatzoglou V, Tabar V, Holodny AI, Vachha B. Resting-State Functional Connectivity of the Middle Frontal Gyrus Can Predict Language Lateralization in Patients with Brain Tumors. AJNR Am J Neuroradiol. 2019 02; 40(2):319-325. PMID: 30630835.
      Citations: 15     Fields:    Translation:Humans
    24. Hatzoglou V, Oh JH, Buck O, Lin X, Lee M, Shukla-Dave A, Young RJ, Peck KK, Vachha B, Holodny AI, Grommes C. Pretreatment dynamic contrast-enhanced MRI biomarkers correlate with progression-free survival in primary central nervous system lymphoma. J Neurooncol. 2018 Nov; 140(2):351-358. PMID: 30073640.
      Citations: 10     Fields:    Translation:Humans
    25. Hamidian S, Vachha B, Jenabi M, Karimi S, Young RJ, Holodny AI, Peck KK. Resting-State Functional Magnetic Resonance Imaging and Probabilistic Diffusion Tensor Imaging Demonstrate That the Greatest Functional and Structural Connectivity in the Hand Motor Homunculus Occurs in the Area of the Thumb. Brain Connect. 2018 08; 8(6):371-379. PMID: 29987948.
      Citations: 4     Fields:    Translation:Humans
    26. Santomasso BD, Park JH, Salloum D, Riviere I, Flynn J, Mead E, Halton E, Wang X, Senechal B, Purdon T, Cross JR, Liu H, Vachha B, Chen X, DeAngelis LM, Li D, Bernal Y, Gonen M, Wendel HG, Sadelain M, Brentjens RJ. Clinical and Biological Correlates of Neurotoxicity Associated with CAR T-cell Therapy in Patients with B-cell Acute Lymphoblastic Leukemia. Cancer Discov. 2018 08; 8(8):958-971. PMID: 29880584.
      Citations: 318     Fields:    Translation:HumansCellsCTClinical Trials
    27. Taunk NK, Oh JH, Shukla-Dave A, Beal K, Vachha B, Holodny A, Hatzoglou V. Early posttreatment assessment of MRI perfusion biomarkers can predict long-term response of lung cancer brain metastases to stereotactic radiosurgery. Neuro Oncol. 2018 03 27; 20(4):567-575. PMID: 29016814.
      Citations: 18     Fields:    Translation:Humans
    28. Sarkar SN, Hackney DB, Greenman RL, Vachha BA, Johnson EA, Nagle S, Moonis G. A subjective and objective comparison of tissue contrast and imaging artifacts present in routine spin echoes and in iterative decomposition of asymmetric spin echoes for soft tissue neck MRI. Eur J Radiol. 2018 May; 102:202-207. PMID: 29685536.
      Citations:    Fields:    Translation:Humans
    29. Black DF, Vachha B, Mian A, Faro SH, Maheshwari M, Sair HI, Petrella JR, Pillai JJ, Welker K. American Society of Functional Neuroradiology-Recommended fMRI Paradigm Algorithms for Presurgical Language Assessment. AJNR Am J Neuroradiol. 2017 Oct; 38(10):E65-E73. PMID: 28860215.
      Citations:    
    30. Chalifoux JR, Vachha B, Moonis G. Imaging of Head and Neck Infections: Diagnostic Considerations, Potential Mimics, and Clinical Management. Semin Roentgenol. 2017 Jan; 52(1):10-16. PMID: 28434498.
      Citations:    Fields:    Translation:Humans
    31. Vachha B, Moonis G, Holodny A. Infections of the Brain and Meninges. Semin Roentgenol. 2017 Jan; 52(1):2-9. PMID: 28434500.
      Citations:    Fields:    Translation:Humans
    32. Vachha BA, Ginat DT, Mallur P, Cunnane M, Moonis G. "Finding a Voice": Imaging Features after Phonosurgical Procedures for Vocal Fold Paralysis. AJNR Am J Neuroradiol. 2016 Sep; 37(9):1574-80. PMID: 27173367.
      Citations: 1     Fields:    Translation:Humans
    33. Vachha BA, Robson CD. Imaging of Pediatric Orbital Diseases. Neuroimaging Clin N Am. 2015 Aug; 25(3):477-501. PMID: 26208421.
      Citations: 4     Fields:    Translation:Humans
    34. Vachha BA, Schaefer PW. Imaging Patterns and Management Algorithms in Acute Stroke: An Update for the Emergency Radiologist. Radiol Clin North Am. 2015 Jul; 53(4):801-26, ix. PMID: 26046512.
      Citations: 6     Fields:    Translation:Humans
    35. Vachha B, Rojas R, Prabhu SP, Bhadelia R, Moonis G. Magnetic resonance imaging in viral and prion diseases of the central nervous system. Top Magn Reson Imaging. 2014 Oct; 23(5):293-302. PMID: 25296274.
      Citations: 1     Fields:    Translation:Humans
    36. Hakimelahi R, Vachha BA, Copen WA, Papini GD, He J, Higazi MM, Lev MH, Schaefer PW, Yoo AJ, Schwamm LH, Gonz?lez RG. Time and diffusion lesion size in major anterior circulation ischemic strokes. Stroke. 2014 Oct; 45(10):2936-41. PMID: 25190444.
      Citations: 20     Fields:    Translation:Humans
    37. Koral K, Vachha B, Gimi B, Zhang S, Ulualp SO, Suter E, Fernandes N, McMenamy J, Booth TN. MRI of the petromastoid canal in children. J Magn Reson Imaging. 2014 Apr; 39(4):966-71. PMID: 24783242.
      Citations: 2     Fields:    Translation:Humans
    38. Vachha B, Brodoefel H, Wilcox C, Hackney DB, Moonis G. Radiation dose reduction in soft tissue neck CT using adaptive statistical iterative reconstruction (ASIR). Eur J Radiol. 2013 Dec; 82(12):2222-6. PMID: 24016832.
      Citations: 12     Fields:    Translation:Humans
    39. Vachha B, Cunnane MB, Mallur P, Moonis G. Losing your voice: etiologies and imaging features of vocal fold paralysis. J Clin Imaging Sci. 2013; 3:15. PMID: 23814687.
      Citations:    
    40. Vachha B, Sun MR, Siewert B, Eisenberg RL. Cystic lesions of the liver. AJR Am J Roentgenol. 2011 Apr; 196(4):W355-66. PMID: 21427297.
      Citations: 42     Fields:    Translation:Humans
    41. Adams RC, Vachha B, Samuelson ML, Keefover-Hicks A, Snodgrass WT. Incidence of new onset metabolic acidosis following enteroplasty for myelomeningocele. J Urol. 2010 Jan; 183(1):302-5. PMID: 19914645.
      Citations: 4     Fields:    Translation:Humans
    42. Gimi B, Kwon J, Liu L, Su Y, Nemani K, Trivedi K, Cui Y, Vachha B, Mason R, Hu W, Lee JB. Cell encapsulation and oxygenation in nanoporous microcontainers. Biomed Microdevices. 2009 Dec; 11(6):1205-12. PMID: 19629700.
      Citations: 10     Fields:    Translation:AnimalsCells
    43. Rollins NK, Vachha B, Srinivasan P, Chia J, Pickering J, Hughes CW, Gimi B. Simple developmental dyslexia in children: alterations in diffusion-tensor metrics of white matter tracts at 3 T. Radiology. 2009 Jun; 251(3):882-91. PMID: 19346513.
      Citations: 25     Fields:    Translation:HumansCells
    44. Vachha B, Adams R. Implications of family environment and language development: comparing typically developing children to those with spina bifida. Child Care Health Dev. 2009 Sep; 35(5):709-16. PMID: 19323671.
      Citations: 3     Fields:    Translation:Humans
    45. Gimi B, Kwon J, Kuznetsov A, Vachha B, Magin RL, Philipson LH, Lee JB. A nanoporous, transparent microcontainer for encapsulated islet therapy. J Diabetes Sci Technol. 2009 Mar; 3(2):297-303. PMID: 19746206.
      Citations: 13     Fields:    Translation:Animals
    46. Patel B, Gimi B, Vachha B, Agadi S, Koral K. Optic nerve and chiasm enlargement in a case of infantile Krabbe disease: quantitative comparison with 26 age-matched controls. Pediatr Radiol. 2008 Jun; 38(6):697-9. PMID: 18438656.
      Citations: 3     Fields:    Translation:Humans
    47. Vachha B, Adams RC, Rollins NK. Limbic tract anomalies in pediatric myelomeningocele and Chiari II malformation: anatomic correlations with memory and learning--initial investigation. Radiology. 2006 Jul; 240(1):194-202. PMID: 16793979.
      Citations: 24     Fields:    Translation:Humans
    48. Vachha B, Adams RC. Memory and selective learning in children with spina bifida-myelomeningocele and shunted hydrocephalus: a preliminary study. Cerebrospinal Fluid Res. 2005 Nov 17; 2:10. PMID: 16293188.
      Citations:    
    49. Vachha B, Adams R. Influence of family environment on language outcomes in children with myelomeningocele. Child Care Health Dev. 2005 Sep; 31(5):589-96. PMID: 16101655.
      Citations: 2     Fields:    Translation:Humans
    50. Riddle R, Morton A, Sampson JD, Vachha B, Adams R. Performance on the NEPSY among children with spina bifida. Arch Clin Neuropsychol. 2005 Mar; 20(2):243-8. PMID: 15708733.
      Citations: 4     Fields:    Translation:Humans
    51. Vachha B, Adams RC. A temperament for learning: The limbic system and myelomeningocele. Cerebrospinal Fluid Res. 2004 Dec 10; 1(1):6. PMID: 15679940.
      Citations:    
    52. Vachha B, Adams R. Myelomeningocele, temperament patterns, and parental perceptions. Pediatrics. 2005 Jan; 115(1):e58-63. PMID: 15579668.
      Citations: 7     Fields:    Translation:Humans
    53. Vachha B, Adams R. Temperament characteristics in school-aged children with spina bifida and shunted hydrocephalus. Eur J Pediatr Surg. 2003 Dec; 13 Suppl 1:S44-6. PMID: 14986641.
      Citations: 1     Fields:    Translation:Humans
    54. Vachha B, Adams R. Language sample analysis in children with myelomeningocele and shunted hydrocephalus. Eur J Pediatr Surg. 2003 Dec; 13 Suppl 1:S36-7. PMID: 14986617.
      Citations: 3     Fields:    Translation:Humans
    55. Vachha B, Adams R. Language differences in young children with myelomeningocele and shunted hydrocephalus. Pediatr Neurosurg. 2003 Oct; 39(4):184-9. PMID: 12944698.
      Citations: 10     Fields:    Translation:Humans
    56. Vachha B, Adams RC. Application of the Token Test with myelomeningocele and shunted hydrocephalus. Eur J Pediatr Surg. 2002 Dec; 12 Suppl 1:S33-4. PMID: 12585253.
      Citations: 2     Fields:    Translation:Humans
    57. Vachha B, Adams RC. Parent and school perceptions of language abilities in children with spina bifida and shunted hydrocephalus. Eur J Pediatr Surg. 2002 Dec; 12 Suppl 1:S31-3. PMID: 12585252.
      Citations: 1     Fields:    Translation:Humans
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