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Jocelyn Farmer MD, PhD

TitleAssociate Professor
InstitutionUMass Chan Medical School
DepartmentMedicine at UMass Chan - Lahey
AddressLahey Hospital and Medical Center
41 Mall Road
Burlington MA 01805
Phone781-744-8442
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    Other Positions
    InstitutionT.H. Chan School of Medicine
    DepartmentMedicine at UMass Chan - Lahey


    Collapse Biography 
    Collapse education and training
    Wake Forest University, Winston-Salem, NC, United StatesBSBiology & Chemistry
    University of Michigan, Ann Arbor, Ann Arbor, MI, United StatesMD
    University of Michigan, Ann Arbor, Ann Arbor, MI, United StatesPHD

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Elmoursi A, DiGiacomo DV, Farmer JR, Barmettler S. Hepatic Manifestations in Common Variable Immunodeficiency Associated With Mortality and Worse Hospital Outcomes in Nationwide Analysis Using National Readmission Database. J Allergy Clin Immunol Pract. 2025 Nov; 13(11):3118-3128.e3. PMID: 40998257.
      Citations:    
    2. Rivi?re JG, Bastarache L, Campos LC, Carot-Sans G, Chin A, Chunara R, Cunningham-Rundles C, Erra L, Farmer J, Garcelon N, Hsieh E, Leavis H, Lee S, Liu L, Kusters M, Lloyd BC, Martinson AK, Mester R, Moore JB, Moshous D, Orange JS, Parrish N, Parker SH, Pasaniuc B, Peng XP, Pergent M, Piera-Jim?nez J, Quinn J, Ramesh S, Roberts K, Robinson PN, Savova G, Scalchunes C, Seidel MG, Simoneau R, Soler-Palacin P, Sullivan KE, Van Gijn M, Wi CI, Zhou D, Tenembaum V, Butte MJ, Rider NL. Proceedings of the second Artificial Intelligence in Primary Immunodeficiency (AIPI) meeting. J Allergy Clin Immunol. 2025 Sep 17. PMID: 40972982.
      Citations:    
    3. Neary CM, Ong MS, Farmer JR. Sociodemographic drivers of care disparity among patients with inborn errors of immunity. Curr Opin Pediatr. 2025 Dec 01; 37(6):613-618. PMID: 40938588.
      Citations:    
    4. Hillier K, Yuen G, Hui A, Kumar S, Roy PG, McColgan JT, Zaldana K, Allard-Chamard H, Premo K, Kaneko N, Ingram N, Barmettler S, Ghebremichael M, Walter JE, Perugino CA, Das J, Farmer JR, Pillai S. Loss of B cell tolerance at the T2/T3a B cell transition is a convergent pathogenic mechanism in common variable immunodeficiency. bioRxiv. 2025 Jun 11. PMID: 40661592.
      Citations:    
    5. Jogdand A, Gilbert KM, Hong JS, Pak AJ, Liu K, Kamau U, Khairnar NV, Ssemaganda HC, DiGiacomo D, Barmettler S, Ong MS, Farmer JR. Utility of serum cytokine testing to differentiate complicated common variable immunodeficiency in resource limited settings. J Allergy Clin Immunol Glob. 2025 Aug; 4(3):100488. PMID: 40497017.
      Citations:    
    6. Faugno E, Galbraith AA, Walsh K, Maglione PJ, Farmer JR, Ong MS. Experiences with diagnostic delay among underserved racial and ethnic patients: a systematic review of the qualitative literature. BMJ Qual Saf. 2025 Feb 19; 34(3):190-200. PMID: 39496473.
      Citations:    
    7. Rider NL, Li Y, Chin AT, DiGiacomo DV, Dutmer C, Farmer JR, Roberts K, Savova G, Ong MS. Evaluating large language model performance to support the diagnosis and management of patients with primary immune disorders. J Allergy Clin Immunol. 2025 Jul; 156(1):81-87. PMID: 39956279.
      Citations:    
    8. Allard-Chamard H, Hillier K, Ramseier ML, Bertocchi A, Kaneko N, Premo K, Yuen G, Karpel M, Mahajan VS, Tsekeri C, Hong JS, Vencic J, Crotty R, Sharda AV, Barmettler S, Westermann-Clark E, Walter JE, Ghebremichael M, Shalek AK, Farmer JR, Pillai S. Congenital T-cell activation impairs transitional-to-follicular B-cell maturation in humans. Blood Adv. 2025 Feb 11; 9(3):520-532. PMID: 39626280.
      Citations:    
    9. Gilbert KM, LeCates RF, Galbraith AA, Maglione PJ, Argetsinger S, Rider NL, Farmer JR, Ong MS. Diagnostic disparities in inborn errors of immunity: From clinical suspicion to diagnosis. J Allergy Clin Immunol Glob. 2025 May; 4(2):100407. PMID: 39991621.
      Citations:    
    10. Casey A, Madhavan VL, Zucker EJ, Farmer JR. Case 39-2024: A 30-Month-Old Boy with Recurrent Fever. N Engl J Med. 2024 Dec 12; 391(23):2256-2265. PMID: 39665657.
      Citations:    
    11. Yin J, Hayes KM, Ong MS, Mizgerd JP, Cunningham-Rundles C, Dominguez I, Barmettler S, Farmer JR, Maglione PJ. Common Variable Immunodeficiency Clinical Manifestations Are Shaped by Presence and Type of Heterozygous NFKB1 Variants. J Allergy Clin Immunol Pract. 2025 Mar; 13(3):639-646. PMID: 39672378.
      Citations:    
    12. Gilbert KM, McLaughlin HM, Farmer JR, Ong MS. Disparities in Genetic Testing for Inborn Errors of Immunity. J Allergy Clin Immunol Pract. 2025 Feb; 13(2):388-395.e3. PMID: 39579980.
      Citations:    
    13. Elmoursi A, Zhou B, Ong MS, Hong JS, Pak A, Tandon M, Sutherland N, DiGiacomo DV, Farmer JR, Barmettler S. A Cross-Sectional Study of Health-Related Quality of Life in Patients with Predominantly Antibody Deficiency. J Clin Immunol. 2024 08 07; 44(8):173. PMID: 39110257.
      Citations:    
    14. Elmoursi A, Zhou B, Ong MS, Hong JS, Pak A, Tandon M, Sutherland N, DiGiacomo DV, Farmer JR, Barmettler S. A Cross-Sectional Study of Health-Related Quality of Life in Patients with Predominantly Antibody Deficiency. Res Sq. 2024 Jul 18. PMID: 39070620.
      Citations:    
    15. Materne E, Zhou B, DiGiacomo D, Farmer JR, Fuleihan R, Sullivan KE, Cunningham-Rundles C, Ballas ZK, Suez D, Barmettler S. Renal complications in patients with predominantly antibody deficiency in the United States Immune Deficiency Network (USIDNET). J Allergy Clin Immunol. 2024 Jul; 154(1):237-242.e1. PMID: 38555979.
      Citations:    
    16. Zhang AM, Elmoursi A, DiGiacomo DV, Zhou B, Tandon M, Hong JS, Yang NJ, Ong MS, Dighe AS, Berrios C, Poznansky MC, Iafrate AJ, Naranbhai V, Balazs A, Pillai S, Farmer JR, Barmettler S. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine response in adults with predominantly antibody deficiency. J Allergy Clin Immunol Glob. 2024 May; 3(2):100234. PMID: 38544577.
      Citations:    
    17. Wang C, Sun B, Wu K, Farmer JR, Ujhazi B, Geier CB, Gordon S, Westermann-Clark E, Savic S, Secord E, Sargur R, Chen K, Jin JJ, Dutmer CM, Kanariou MG, Adeli M, Palma P, Bonfim C, Lycopoulou E, Wolska-Kusnierz B, Dbaibo G, Bleesing J, Moshous D, Neven B, Schuetz C, Geha RS, Notarangelo LD, Miano M, Buchbinder DK, Csomos K, Wang W, Wang JY, Wang X, Walter JE. Clinical, immunological features, treatments, and outcomes of autoimmune hemolytic anemia in patients with RAG deficiency. Blood Adv. 2024 02 13; 8(3):603-607. PMID: 37883797.
      Citations:    
    18. DiGiacomo DV, Roelstraete B, Lebwohl B, Green PHR, Hammarstr?m L, Farmer JR, Khalili H, Ludvigsson JF. Predominantly antibody deficiency and the association with celiac disease in Sweden: A nationwide case-control study. Ann Allergy Asthma Immunol. 2024 06; 132(6):752-758.e2. PMID: 38331244.
      Citations:    
    19. Zonozi R, Walters LC, Shulkin A, Naranbhai V, Nithagon P, Sauvage G, Kaeske C, Cosgrove K, Nathan A, Tano-Menka R, Gayton AC, Getz MA, Senjobe F, Worrall D, Iafrate AJ, Fromson C, Montesi SB, Rao DA, Sparks JA, Wallace ZS, Farmer JR, Walker BD, Charles RC, Laliberte K, Niles JL, Gaiha GD. T cell responses to SARS-CoV-2 infection and vaccination are elevated in B cell deficiency and reduce risk of severe COVID-19. Sci Transl Med. 2023 11 29; 15(724):eadh4529. PMID: 38019932.
      Citations:    
    20. Ong MS, Rider NL, Stein S, Maglione PJ, Galbraith A, DiGiacomo DV, Farmer JR. Racial and ethnic disparities in early mortality among patients with inborn errors of immunity. J Allergy Clin Immunol. 2024 01; 153(1):335-340.e1. PMID: 37802474.
      Citations:    
    21. Tandon M, DiGiacomo DV, Zhou B, Hesterberg P, Rosenberg CE, Barmettler S, Farmer JR. Response to SARS-CoV-2 initial series and additional dose vaccine in pediatric patients with predominantly antibody deficiency. Front Immunol. 2023; 14:1217718. PMID: 37575247.
      Citations:    
    22. Allard-Chamard H, Kaneko N, Bertocchi A, Sun N, Boucau J, Kuo HH, Farmer JR, Perugino C, Mahajan VS, Murphy SJH, Premo K, Diefenbach T, Ghebremichael M, Yuen G, Kotta A, Akman Z, Lichterfeld M, Walker BD, Yu XG, Moriyama M, Maehara T, Nakamura S, Stone JH, Padera RF, Pillai S. Extrafollicular IgD-CD27-CXCR5-CD11c- DN3 B cells infiltrate inflamed tissues in autoimmune fibrosis and in severe COVID-19. Cell Rep. 2023 06 27; 42(6):112630. PMID: 37300833.
      Citations:    
    23. Farmer JR, Galbraith A, Ong MS. Association of inborn errors of immunity with severe COVID-19 and post-acute sequelae of COVID-19. J Allergy Clin Immunol Pract. 2023 08; 11(8):2616-2617.e2. PMID: 37244439.
      Citations:    
    24. DiGiacomo DV, Roelstraete B, Hammarstr?m L, Farmer JR, Khalili H, Ludvigsson JF. Predominant Antibody Deficiency and Risk of Microscopic Colitis: a Nationwide Case-Control Study in Sweden. J Clin Immunol. 2023 08; 43(6):1426-1435. PMID: 37162615.
      Citations:    
    25. Maron JS, Conroy M, Naranbai V, Samarakoon U, Motazedi T, Farmer JR, Freeman E, Banerji A, Bartsch YC, Gregory DJ, Poznansky MC, Alter G, Blumenthal KG. Differential Severe Acute Respiratory Syndrome Coronavirus 2 Antibody Profiles After Allergic Reactions to Messenger RNA Coronavirus Disease 2019 Vaccine. J Infect Dis. 2022 09 28; 226(7):1231-1236. PMID: 35325158.
      Citations:    
    26. DiGiacomo DV, Shay JE, Crotty R, Yang N, Bloom P, Corey K, Barmettler S, Farmer JR. Liver Stiffness by Transient Elastography Correlates With Degree of Portal Hypertension in Common Variable Immunodeficiency Patients With Nodular Regenerative Hyperplasia. Front Immunol. 2022; 13:864550. PMID: 35603209.
      Citations:    
    27. Barmettler S, DiGiacomo DV, Yang NJ, Lam T, Naranbhai V, Dighe AS, Burke KE, Blumenthal KG, Ling M, Hesterberg PE, Saff RR, MacLean J, Ofoman O, Berrios C, St Denis KJ, Lam EC, Gregory D, Iafrate AJ, Poznansky M, Lee H, Balazs A, Pillai S, Farmer JR. Response to Severe Acute Respiratory Syndrome Coronavirus 2 Initial Series and Additional Dose Vaccine in Patients With Predominant Antibody Deficiency. J Allergy Clin Immunol Pract. 2022 06; 10(6):1622-1634.e4. PMID: 35381395.
      Citations:    
    28. Kaneko N, Boucau J, Kuo HH, Perugino C, Mahajan VS, Farmer JR, Liu H, Diefenbach TJ, Piechocka-Trocha A, Lefteri K, Waring MT, Premo KR, Walker BD, Li JZ, Gaiha G, Yu XG, Lichterfeld M, Padera RF, Pillai S. Temporal changes in T cell subsets and expansion of cytotoxic CD4+ T cells in the lungs in severe COVID-19. Clin Immunol. 2022 04; 237:108991. PMID: 35364330.
      Citations:    
    29. Naranbhai V, Pernat CA, Gavralidis A, St Denis KJ, Lam EC, Spring LM, Isakoff SJ, Farmer JR, Zubiri L, Hobbs GS, How J, Brunner AM, Fathi AT, Peterson JL, Sakhi M, Hambelton G, Denault EN, Mortensen LJ, Perriello LA, Bruno MN, Bertaux BY, Lawless AR, Jackson MA, Niehoff E, Barabell C, Nambu CN, Nakajima E, Reinicke T, Bowes C, Berrios-Mairena CJ, Ofoman O, Kirkpatrick GE, Thierauf JC, Reynolds K, Willers H, Beltran WG, Dighe AS, Saff R, Blumenthal K, Sullivan RJ, Chen YB, Kim A, Bardia A, Balazs AB, Iafrate AJ, Gainor JF. Immunogenicity and Reactogenicity of SARS-CoV-2 Vaccines in Patients With Cancer: The CANVAX Cohort Study. J Clin Oncol. 2022 01 01; 40(1):12-23. PMID: 34752147.
      Citations:    
    30. Zubiri L, Molina GE, Mooradian MJ, Cohen J, Durbin SM, Petrillo L, Boland GM, Juric D, Dougan M, Thomas MF, Faje AT, Rengarajan M, Guidon AC, Chen ST, Okin D, Medoff BD, Nasrallah M, Kohler MJ, Schoenfeld SR, Karp-Leaf RS, Sise ME, Neilan TG, Zlotoff DA, Farmer JR, Bardia A, Sullivan RJ, Blum SM, Semenov YR, Villani AC, Reynolds KL. Effect of a multidisciplinary Severe Immunotherapy Complications Service on outcomes for patients receiving immune checkpoint inhibitor therapy for cancer. J Immunother Cancer. 2021 09; 9(9). PMID: 34544895.
      Citations:    
    31. Cotsapas C, Saarela J, Farmer JR, Scaria V, Abraham RS. Do monogenic inborn errors of immunity cause susceptibility to severe COVID-19? J Clin Invest. 2021 07 15; 131(14). PMID: 34061775.
      Citations:    
    32. Lee DJ, Lee HJ, Farmer JR, Reynolds KL. Mechanisms Driving Immune-Related Adverse Events in Cancer Patients Treated with Immune Checkpoint Inhibitors. Curr Cardiol Rep. 2021 07 01; 23(8):98. PMID: 34196833.
      Citations:    
    33. Molina GE, Zubiri L, Cohen JV, Durbin SM, Petrillo L, Allen IM, Murciano-Goroff YR, Dougan M, Thomas MF, Faje AT, Rengarajan M, Guidon AC, Chen ST, Okin D, Medoff BD, Nasrallah M, Kohler MJ, Schoenfeld SR, Karp Leaf RS, Sise ME, Neilan TG, Zlotoff DA, Farmer JR, Mooradian MJ, Bardia A, Mai M, Sullivan RJ, Semenov YR, Villani AC, Reynolds KL. Temporal Trends and Outcomes Among Patients Admitted for Immune-Related Adverse Events: A Single-Center Retrospective Cohort Study from 2011 to 2018. Oncologist. 2021 06; 26(6):514-522. PMID: 33655682.
      Citations:    
    34. Kaneko N, Boucau J, Kuo HH, Perugino C, Mahajan VS, Farmer JR, Liu H, Diefenbach TJ, Piechocka-Trocha A, Lefteri K, Waring MT, Premo KR, Walker BD, Li JZ, Gaiha G, Yu XG, Lichterfeld M, Padera RF, Pillai S. Expansion of Cytotoxic CD4+ T cells in the lungs in severe COVID-19. medRxiv. 2021 Mar 26. PMID: 33791730.
      Citations:    
    35. Hale JE, Platt CD, Bonilla FA, Hay BN, Sullivan JL, Johnston AM, Pasternack MS, Hesterberg PE, Meissner HC, Cooper ER, Barmettler S, Farmer JR, Fisher D, Walter JE, Yang NJ, Sahai I, Eaton RB, DeMaria A, Notarangelo LD, Pai SY, Comeau AM. Ten Years of Newborn Screening for Severe Combined Immunodeficiency (SCID) in Massachusetts. J Allergy Clin Immunol Pract. 2021 05; 9(5):2060-2067.e2. PMID: 33607339.
      Citations: 8     Fields:    Translation:HumansPHPublic Health
    36. Farmer JR, Uzel G. Mapping Out Autoimmunity Control in Primary Immune Regulatory Disorders. J Allergy Clin Immunol Pract. 2021 02; 9(2):653-659. PMID: 33358993.
      Citations:    
    37. Geier CB, Farmer JR, Foldvari Z, Ujhazi B, Steininger J, Sleasman JW, Parikh S, Dilley MA, Pai SY, Henderson L, Hazen M, Neven B, Moshous D, Sharapova SO, Mihailova S, Yankova P, Naumova E, ?zen S, Byram K, Fernandez J, Wolf HM, Eibl MM, Notarangelo LD, Calabrese LH, Walter JE. Vasculitis as a Major Morbidity Factor in Patients With Partial RAG Deficiency. Front Immunol. 2020; 11:574738. PMID: 33193364.
      Citations:    
    38. Broyles AD, Banerji A, Barmettler S, Biggs CM, Blumenthal K, Brennan PJ, Breslow RG, Brockow K, Buchheit KM, Cahill KN, Cernadas J, Chiriac AM, Crestani E, Demoly P, Dewachter P, Dilley M, Farmer JR, Foer D, Fried AJ, Garon SL, Giannetti MP, Hepner DL, Hong DI, Hsu JT, Kothari PH, Kyin T, Lax T, Lee MJ, Lee-Sarwar K, Liu A, Logsdon S, Louisias M, MacGinnitie A, Maciag M, Minnicozzi S, Norton AE, Otani IM, Park M, Patil S, Phillips EJ, Picard M, Platt CD, Rachid R, Rodriguez T, Romano A, Stone CA, Torres MJ, Verd? M, Wang AL, Wickner P, Wolfson AR, Wong JT, Yee C, Zhou J, Castells M. Practical Guidance for the Evaluation and Management of Drug Hypersensitivity: Specific Drugs. J Allergy Clin Immunol Pract. 2020 10; 8(9S):S16-S116. PMID: 33039007.
      Citations:    
    39. Kaneko N, Kuo HH, Boucau J, Farmer JR, Allard-Chamard H, Mahajan VS, Piechocka-Trocha A, Lefteri K, Osborn M, Bals J, Bartsch YC, Bonheur N, Caradonna TM, Chevalier J, Chowdhury F, Diefenbach TJ, Einkauf K, Fallon J, Feldman J, Finn KK, Garcia-Broncano P, Hartana CA, Hauser BM, Jiang C, Kaplonek P, Karpell M, Koscher EC, Lian X, Liu H, Liu J, Ly NL, Michell AR, Rassadkina Y, Seiger K, Sessa L, Shin S, Singh N, Sun W, Sun X, Ticheli HJ, Waring MT, Zhu AL, Alter G, Li JZ, Lingwood D, Schmidt AG, Lichterfeld M, Walker BD, Yu XG, Padera RF, Pillai S. Loss of Bcl-6-Expressing T Follicular Helper Cells and Germinal Centers in COVID-19. Cell. 2020 10 01; 183(1):143-157.e13. PMID: 32877699.
      Citations:    
    40. Kaneko N, Kuo HH, Boucau J, Farmer JR, Allard-Chamard H, Mahajan VS, Piechocka-Trocha A, Lefteri K, Osborn M, Bals J, Bartsch YC, Bonheur N, Caradonna TM, Chevalier J, Chowdhury F, Diefenbach TJ, Einkauf K, Fallon J, Feldman J, Finn KK, Garcia-Broncano P, Hartana CA, Hauser BM, Jiang C, Kaplonek P, Karpell M, Koscher EC, Lian X, Liu H, Liu J, Ly NL, Michell AR, Rassadkina Y, Seiger K, Sessa L, Shin S, Singh N, Sun W, Sun X, Ticheli HJ, Waring MT, Zhu AL, Li J, Lingwood D, Schmidt AG, Lichterfeld M, Walker BD, Yu X, Padera RF, Pillai S. The Loss of Bcl-6 Expressing T Follicular Helper Cells and the Absence of Germinal Centers in COVID-19. SSRN. 2020 Jul 16; 3652322. PMID: 32742244.
      Citations:    
    41. Crotty R, Taylor MS, Farmer JR, Kakar S, Yilmaz F, Ardeniz ?, Patil DT, Deshpande V. Spectrum of Hepatic Manifestations of Common Variable Immunodeficiency. Am J Surg Pathol. 2020 05; 44(5):617-625. PMID: 32187043.
      Citations:    
    42. Barmettler S, Ong MS, Farmer JR, Yang N, Cobbold M, Walter JE, Long AA, Camargo CA. Gastrointestinal manifestations in common variable immunodeficiency (CVID) are associated with an altered immunophenotype including B- and T-cell dysregulation. J Allergy Clin Immunol Pract. 2020 04; 8(4):1436-1438.e1. PMID: 31704440.
      Citations:    
    43. Farmer JR, Mahajan VS. Molecular Diagnosis of Inherited Immune Disorders. Clin Lab Med. 2019 12; 39(4):685-697. PMID: 31668278.
      Citations:    
    44. Maxey-Jones CL, Palmerton A, Farmer JR, Bateman BT. Difficult Airway Management Caused by Local Anesthetic Allergy During Emergent Cesarean Delivery: A Case Report. A A Case Rep. 2017 Aug 01; 9(3):84-86. PMID: 28448320.
      Citations:    
    45. Walter JE, Farmer JR, Foldvari Z, Torgerson TR, Cooper MA. Mechanism-Based Strategies for the Management of Autoimmunity and Immune Dysregulation in Primary Immunodeficiencies. J Allergy Clin Immunol Pract. 2016 Nov - Dec; 4(6):1089-1100. PMID: 27836058.
      Citations:    
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