 Hemolysin Proteins
"Hemolysin Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Proteins from BACTERIA and FUNGI that are soluble enough to be secreted to target ERYTHROCYTES and insert into the membrane to form beta-barrel pores. Biosynthesis may be regulated by HEMOLYSIN FACTORS.
| Descriptor ID |
D006460
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| MeSH Number(s) |
D12.776.543.695.444
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Hemolysin Proteins".
Below are MeSH descriptors whose meaning is more specific than "Hemolysin Proteins".
This graph shows the total number of publications written about "Hemolysin Proteins" by people in this website by year, and whether "Hemolysin Proteins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 | | 2000 | 0 | 1 | 1 | | 2001 | 0 | 1 | 1 | | 2003 | 0 | 2 | 2 | | 2004 | 0 | 2 | 2 | | 2005 | 0 | 1 | 1 | | 2006 | 1 | 1 | 2 | | 2007 | 2 | 0 | 2 | | 2008 | 1 | 0 | 1 | | 2010 | 1 | 1 | 2 | | 2011 | 1 | 1 | 2 | | 2012 | 3 | 1 | 4 | | 2013 | 2 | 0 | 2 | | 2014 | 3 | 0 | 3 | | 2015 | 2 | 0 | 2 |
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Below are the most recent publications written about "Hemolysin Proteins" by people in Profiles.
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Durmaz E, Hu Y, Aroian RV, Klaenhammer TR. Intracellular and Extracellular Expression of Bacillus thuringiensis Crystal Protein Cry5B in Lactococcus lactis for Use as an Anthelminthic. Appl Environ Microbiol. 2015 Dec 18; 82(4):1286-94.
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Wu CC, Hu Y, Miller M, Aroian RV, Sailor MJ. Protection and Delivery of Anthelmintic Protein Cry5B to Nematodes Using Mesoporous Silicon Particles. ACS Nano. 2015 Jun 23; 9(6):6158-67.
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Gupta R, Ghosh S, Monks B, DeOliveira RB, Tzeng TC, Kalantari P, Nandy A, Bhattacharjee B, Chan J, Ferreira F, Rathinam V, Sharma S, Lien E, Silverman N, Fitzgerald K, Firon A, Trieu-Cuot P, Henneke P, Golenbock DT. RNA and ß-hemolysin of group B Streptococcus induce interleukin-1ß (IL-1ß) by activating NLRP3 inflammasomes in mouse macrophages. J Biol Chem. 2014 May 16; 289(20):13701-5.
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St Jean AT, Swofford CA, Panteli JT, Brentzel ZJ, Forbes NS. Bacterial delivery of Staphylococcus aureus a-hemolysin causes regression and necrosis in murine tumors. Mol Ther. 2014 Jul; 22(7):1266-74.
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Swofford CA, St Jean AT, Panteli JT, Brentzel ZJ, Forbes NS. Identification of Staphylococcus aureus a-hemolysin as a protein drug that is secreted by anticancer bacteria and rapidly kills cancer cells. Biotechnol Bioeng. 2014 Jun; 111(6):1233-45.
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Hu Y, Miller MM, Derman AI, Ellis BL, Monnerat RG, Pogliano J, Aroian RV. Bacillus subtilis strain engineered for treatment of soil-transmitted helminth diseases. Appl Environ Microbiol. 2013 Sep; 79(18):5527-32.
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Urban JF, Hu Y, Miller MM, Scheib U, Yiu YY, Aroian RV. Bacillus thuringiensis-derived Cry5B has potent anthelmintic activity against Ascaris suum. PLoS Negl Trop Dis. 2013; 7(6):e2263.
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Hui F, Scheib U, Hu Y, Sommer RJ, Aroian RV, Ghosh P. Structure and glycolipid binding properties of the nematicidal protein Cry5B. Biochemistry. 2012 Dec 11; 51(49):9911-21.
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Hu Y, Zhan B, Keegan B, Yiu YY, Miller MM, Jones K, Aroian RV. Mechanistic and single-dose in vivo therapeutic studies of Cry5B anthelmintic action against hookworms. PLoS Negl Trop Dis. 2012; 6(11):e1900.
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Hu Y, Aroian RV. Bacterial pore-forming proteins as anthelmintics. Invert Neurosci. 2012 Jun; 12(1):37-41.
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