Cilia

"Cilia" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Populations of thin, motile processes found covering the surface of ciliates (CILIOPHORA) or the free surface of the cells making up ciliated EPITHELIUM. Each cilium arises from a basic granule in the superficial layer of CYTOPLASM. The movement of cilia propels ciliates through the liquid in which they live. The movement of cilia on a ciliated epithelium serves to propel a surface layer of mucus or fluid. (King & Stansfield, A Dictionary of Genetics, 4th ed)

Descriptor ID	D002923
MeSH Number(s)	A11.284.180.165
Concept/Terms	Cilia Cilia Cilium

Below are MeSH descriptors whose meaning is more general than "Cilia".

Anatomy [A]
Cells [A11]
Cellular Structures [A11.284]
Cell Surface Extensions [A11.284.180]
Cilia [A11.284.180.165]

Below are MeSH descriptors whose meaning is related to "Cilia".

Below are MeSH descriptors whose meaning is more specific than "Cilia".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Cilia" by people in this website by year, and whether "Cilia" was a major or minor topic of these publications.

Bar chart showing 116 publications over 24 distinct years, with a maximum of 11 publications in 2017

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2000	1	0	1
2002	1	3	4
2003	4	0	4
2004	4	2	6
2005	2	3	5
2006	2	0	2
2008	2	1	3
2009	2	2	4
2010	2	2	4
2011	4	1	5
2012	1	2	3
2013	6	0	6
2014	6	2	8
2015	5	5	10
2016	0	3	3
2017	6	5	11
2018	1	2	3
2019	7	3	10
2020	2	1	3
2021	4	2	6
2022	1	2	3
2023	2	2	4
2024	2	2	4
2025	3	1	4

Below are the most recent publications written about "Cilia" by people in Profiles.

Hou Y, Omi OA, Stuck MW, Cheng X, Walker B, Lam YW, Schmoker AM, Nguyen SN, Gonzalez-Perez MP, Ballif BA, Lechtreck KF, Witman GB, Pazour GJ. Activation of the ciliary kinase CDKL5 is mediated by the cyclin-dependent kinase CDK20/LF2 to control flagellar length. PLoS Biol. 2025 Dec; 23(12):e3003560.

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Pazour GJ. Cilia.Pro database of ciliary proteins from vertebrates, Chlamydomonas, and Caenorhabditis. Mol Biol Cell. 2025 Sep 01; 36(9):mr8.

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Ahmed M, Fischer S, Robert KL, Lange KI, Stuck MW, Best S, Johnson CA, Pazour GJ, Blacque OE, Nandadasa S. Cleavage of the Meckel-Gruber syndrome protein TMEM67 by ADAMTS9 uncouples Wnt signaling and ciliogenesis. Nat Commun. 2025 May 28; 16(1):4946.

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Yap YT, Pan J, Xu J, Yuan S, Niu C, Zheng C, Li W, Zhou T, Li T, Zhang Y, Holtzman MJ, Pazour GJ, Hess RA, Kelly CV, Tour? A, Brody SL, Zhang Z. Role of intraflagellar transport protein IFT140 in the formation and function of motile cilia in mammals. Cell Mol Life Sci. 2025 May 10; 82(1):198.

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Lewis TR, Castillo CM, Klementieva NV, Hsu Y, Hao Y, Spencer WJ, Drack AV, Pazour GJ, Arshavsky VY. Contribution of intraflagellar transport to compartmentalization and maintenance of the photoreceptor cell. Proc Natl Acad Sci U S A. 2024 Aug 20; 121(34):e2408551121.

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Kumari A, Caliz AD, Yoo HJ, Kant S, Vertii A. TNF-alpha promotes cilia elongation via mixed lineage kinases signaling in mouse fibroblasts and human RPE-1 cells. Cytoskeleton (Hoboken). 2024 Nov; 81(11):639-647.

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Patel MB, Griffin PJ, Olson SF, Dai J, Hou Y, Malik T, Das P, Zhang G, Zhao W, Witman GB, Lechtreck KF. Distribution and bulk flow analyses of the intraflagellar transport (IFT) motor kinesin-2 support an "on-demand" model for Chlamydomonas ciliary length control. Cytoskeleton (Hoboken). 2024 Nov; 81(11):586-604.

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Hoque M, Li FQ, Weber WD, Chen JJ, Kim EN, Kuo PL, Visconti PE, Takemaru KI. The Cby3/ciBAR1 complex positions the annulus along the sperm flagellum during spermiogenesis. J Cell Biol. 2024 03 04; 223(3).

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Gupta M, Pazour GJ. Intraflagellar transport: A critical player in photoreceptor development and the pathogenesis of retinal degenerative diseases. Cytoskeleton (Hoboken). 2024 Nov; 81(11):556-568.

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Francis RJB, San Agustin JT, Szabo Rogers HL, Cui C, Jonassen JA, Eguether T, Follit JA, Lo CW, Pazour GJ. Autonomous and non-cell autonomous role of cilia in structural birth defects in mice. PLoS Biol. 2023 12; 21(12):e3002425.

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