TRPP Cation Channels

"TRPP Cation Channels" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A subgroup of TRP cation channels that are widely expressed in various cell types. Defects are associated with POLYCYSTIC KIDNEY DISEASES.

Descriptor ID	D050396
MeSH Number(s)	D12.776.157.530.400.150.900 D12.776.157.530.400.901.777 D12.776.543.585.400.150.900 D12.776.543.585.400.901.777
Concept/Terms	TRPP Cation Channels TRPP Cation Channels Cation Channels, TRPP Channels, TRPP Cation Polycystins

Below are MeSH descriptors whose meaning is more general than "TRPP Cation Channels".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Carrier Proteins [D12.776.157]
Membrane Transport Proteins [D12.776.157.530]
Ion Channels [D12.776.157.530.400]
Calcium Channels [D12.776.157.530.400.150]
TRPP Cation Channels [D12.776.157.530.400.150.900]
Transient Receptor Potential Channels [D12.776.157.530.400.901]
TRPP Cation Channels [D12.776.157.530.400.901.777]
Membrane Proteins [D12.776.543]
Membrane Transport Proteins [D12.776.543.585]
Ion Channels [D12.776.543.585.400]
Calcium Channels [D12.776.543.585.400.150]
TRPP Cation Channels [D12.776.543.585.400.150.900]
Transient Receptor Potential Channels [D12.776.543.585.400.901]
TRPP Cation Channels [D12.776.543.585.400.901.777]

Below are MeSH descriptors whose meaning is related to "TRPP Cation Channels".

Below are MeSH descriptors whose meaning is more specific than "TRPP Cation Channels".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "TRPP Cation Channels" by people in this website by year, and whether "TRPP Cation Channels" was a major or minor topic of these publications.

Bar chart showing 17 publications over 15 distinct years, with a maximum of 2 publications in 2004 and 2006

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	0	1	1
2003	0	1	1
2004	0	2	2
2005	0	1	1
2006	1	1	2
2007	1	0	1
2008	0	1	1
2010	0	1	1
2011	0	1	1
2013	0	1	1
2014	0	1	1
2017	1	0	1
2019	1	0	1
2021	1	0	1
2024	1	0	1

Below are the most recent publications written about "TRPP Cation Channels" by people in Profiles.

Smith AO, Frantz WT, Preval KM, Edwards YJK, Ceol CJ, Jonassen JA, Pazour GJ. The Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) oncogene is upregulated in cystic epithelial cells revealing a potential new target for polycystic kidney disease. PLoS Genet. 2024 Dec; 20(12):e1011510.

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Smith AO, Jonassen JA, Preval KM, Davis RJ, Pazour GJ. c-Jun N-terminal kinase (JNK) signaling contributes to cystic burden in polycystic kidney disease. PLoS Genet. 2021 12; 17(12):e1009711.

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Pazour GJ, Quarmby L, Smith AO, Desai PB, Schmidts M. Cilia in cystic kidney and other diseases. Cell Signal. 2020 05; 69:109519.

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Monis WJ, Faundez V, Pazour GJ. BLOC-1 is required for selective membrane protein trafficking from endosomes to primary cilia. J Cell Biol. 2017 07 03; 216(7):2131-2150.

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Greer YE, Westlake CJ, Gao B, Bharti K, Shiba Y, Xavier CP, Pazour GJ, Yang Y, Rubin JS. Casein kinase 1d functions at the centrosome and Golgi to promote ciliogenesis. Mol Biol Cell. 2014 May; 25(10):1629-40.

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Ma M, Tian X, Igarashi P, Pazour GJ, Somlo S. Loss of cilia suppresses cyst growth in genetic models of autosomal dominant polycystic kidney disease. Nat Genet. 2013 Sep; 45(9):1004-12.

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Paul E, Thiele EA, Shailam R, Rosales AM, Sadow PM. Case records of the Massachusetts General Hospital. Case 26-2011. A 7-year-old boy with a complex cyst in the kidney. N Engl J Med. 2011 Aug 25; 365(8):743-51.

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Yang Y, Cochran DA, Gargano MD, King I, Samhat NK, Burger BP, Sabourin KR, Hou Y, Awata J, Parry DA, Marshall WF, Witman GB, Lu X. Regulation of flagellar motility by the conserved flagellar protein CG34110/Ccdc135/FAP50. Mol Biol Cell. 2011 Apr; 22(7):976-87.

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Hurd T, Zhou W, Jenkins P, Liu CJ, Swaroop A, Khanna H, Martens J, Hildebrandt F, Margolis B. The retinitis pigmentosa protein RP2 interacts with polycystin 2 and regulates cilia-mediated vertebrate development. Hum Mol Genet. 2010 Nov 15; 19(22):4330-44.

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Canaud G, Knebelmann B, Harris PC, Vrtovsnik F, Correas JM, Pallet N, Heyer CM, Letavernier E, Bienaim? F, Thervet E, Martinez F, Terzi F, Legendre C. Therapeutic mTOR inhibition in autosomal dominant polycystic kidney disease: What is the appropriate serum level? Am J Transplant. 2010 Jul; 10(7):1701-6.

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