"TRPC Cation Channels" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subgroup of TRP cation channels that contain 3-4 ANKYRIN REPEAT DOMAINS and a conserved C-terminal domain. Members are highly expressed in the CENTRAL NERVOUS SYSTEM. Selectivity for calcium over sodium ranges from 0.5 to 10.
Descriptor ID |
D050052
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MeSH Number(s) |
D12.776.157.530.400.901.500 D12.776.543.585.400.901.500
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Concept/Terms |
TRPC Cation Channels- TRPC Cation Channels
- Cation Channels, TRPC
- Channels, TRPC Cation
- Transient Receptor Potential Channels, Type C
- Transient Receptor Potential Cation Channel Subfamily C
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Below are MeSH descriptors whose meaning is more general than "TRPC Cation Channels".
Below are MeSH descriptors whose meaning is more specific than "TRPC Cation Channels".
This graph shows the total number of publications written about "TRPC Cation Channels" by people in this website by year, and whether "TRPC Cation Channels" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2004 | 0 | 1 | 1 |
2006 | 0 | 1 | 1 |
2009 | 1 | 0 | 1 |
2010 | 0 | 2 | 2 |
2012 | 2 | 0 | 2 |
2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "TRPC Cation Channels" by people in Profiles.
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Mukhopadhyay D, Goel HL, Xiong C, Goel S, Kumar A, Li R, Zhu LJ, Clark JL, Brehm MA, Mercurio AM. The calcium channel TRPC6 promotes chemotherapy-induced persistence by regulating integrin a6 mRNA splicing. Cell Rep. 2023 11 28; 42(11):113347.
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Carrasquillo R, Tian D, Krishna S, Pollak MR, Greka A, Schl?ndorff J. SNF8, a member of the ESCRT-II complex, interacts with TRPC6 and enhances its channel activity. BMC Cell Biol. 2012 Nov 21; 13:33.
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Molnar T, Barabas P, Birnbaumer L, Punzo C, Kefalov V, Kri?aj D. Store-operated channels regulate intracellular calcium in mammalian rods. J Physiol. 2012 Aug 01; 590(15):3465-81.
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Liu X, Ong HL, Pani B, Johnson K, Swaim WB, Singh B, Ambudkar I. Effect of cell swelling on ER/PM junctional interactions and channel assembly involved in SOCE. Cell Calcium. 2010 Jun; 47(6):491-9.
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Bergmann A. The role of ubiquitylation for the control of cell death in Drosophila. Cell Death Differ. 2010 Jan; 17(1):61-7.
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Schl?ndorff J, Del Camino D, Carrasquillo R, Lacey V, Pollak MR. TRPC6 mutations associated with focal segmental glomerulosclerosis cause constitutive activation of NFAT-dependent transcription. Am J Physiol Cell Physiol. 2009 Mar; 296(3):C558-69.
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Abdullaev IF, Bisaillon JM, Potier M, Gonzalez JC, Motiani RK, Trebak M. Stim1 and Orai1 mediate CRAC currents and store-operated calcium entry important for endothelial cell proliferation. Circ Res. 2008 Nov 21; 103(11):1289-99.
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Sutton KA, Jungnickel MK, Ward CJ, Harris PC, Florman HM. Functional characterization of PKDREJ, a male germ cell-restricted polycystin. J Cell Physiol. 2006 Nov; 209(2):493-500.
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Sutton KA, Jungnickel MK, Wang Y, Cullen K, Lambert S, Florman HM. Enkurin is a novel calmodulin and TRPC channel binding protein in sperm. Dev Biol. 2004 Oct 15; 274(2):426-35.
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Li HS, Montell C. TRP and the PDZ protein, INAD, form the core complex required for retention of the signalplex in Drosophila photoreceptor cells. J Cell Biol. 2000 Sep 18; 150(6):1411-22.