Inositol 1,4,5-Trisphosphate Receptors
"Inositol 1,4,5-Trisphosphate Receptors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Intracellular receptors that bind to INOSITOL 1,4,5-TRISPHOSPHATE and play an important role in its intracellular signaling. Inositol 1,4,5-trisphosphate receptors are calcium channels that release CALCIUM in response to increased levels of inositol 1,4,5-trisphosphate in the CYTOPLASM.
| Descriptor ID |
D053496
|
| MeSH Number(s) |
D12.776.157.530.400.150.760 D12.776.543.550.450.150.760 D12.776.543.585.400.150.760 D12.776.826.179
|
| Concept/Terms |
Inositol 1,4,5-Trisphosphate Receptors- Inositol 1,4,5-Trisphosphate Receptors
- INSP3 Receptor
- Receptor, INSP3
- IP3 Receptor
- Receptor, IP3
- Inositol 1,4,5-Triphosphate Receptors
- Receptor, Inositol-1,4,5-triphosphate
- Inositol-1,4,5-Triphosphate Receptor
- 1,4,5-INTP Receptor
- Inositol Triphosphate Receptor
- Receptor, Inositol Triphosphate
- Triphosphate Receptor, Inositol
|
Below are MeSH descriptors whose meaning is more general than "Inositol 1,4,5-Trisphosphate Receptors".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Carrier Proteins [D12.776.157]
- Membrane Transport Proteins [D12.776.157.530]
- Ion Channels [D12.776.157.530.400]
- Calcium Channels [D12.776.157.530.400.150]
- Inositol 1,4,5-Trisphosphate Receptors [D12.776.157.530.400.150.760]
- Membrane Proteins [D12.776.543]
- Membrane Glycoproteins [D12.776.543.550]
- Ion Channels [D12.776.543.550.450]
- Calcium Channels [D12.776.543.550.450.150]
- Inositol 1,4,5-Trisphosphate Receptors [D12.776.543.550.450.150.760]
- Membrane Transport Proteins [D12.776.543.585]
- Ion Channels [D12.776.543.585.400]
- Calcium Channels [D12.776.543.585.400.150]
- Inositol 1,4,5-Trisphosphate Receptors [D12.776.543.585.400.150.760]
- Receptors, Cytoplasmic and Nuclear [D12.776.826]
- Inositol 1,4,5-Trisphosphate Receptors [D12.776.826.179]
Below are MeSH descriptors whose meaning is more specific than "Inositol 1,4,5-Trisphosphate Receptors".
This graph shows the total number of publications written about "Inositol 1,4,5-Trisphosphate Receptors" by people in this website by year, and whether "Inositol 1,4,5-Trisphosphate Receptors" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 1999 | 0 | 4 | 4 |
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 2 | 2 |
| 2002 | 0 | 2 | 2 |
| 2003 | 0 | 2 | 2 |
| 2004 | 0 | 3 | 3 |
| 2005 | 0 | 2 | 2 |
| 2006 | 1 | 1 | 2 |
| 2008 | 1 | 2 | 3 |
| 2009 | 2 | 0 | 2 |
| 2010 | 2 | 1 | 3 |
| 2011 | 2 | 0 | 2 |
| 2012 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 1 | 2 |
| 2017 | 0 | 1 | 1 |
| 2019 | 2 | 1 | 3 |
To return to the timeline,
click here.
Below are the most recent publications written about "Inositol 1,4,5-Trisphosphate Receptors" by people in Profiles.
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Wakai T, Mehregan A, Fissore RA. Ca2+ Signaling and Homeostasis in Mammalian Oocytes and Eggs. Cold Spring Harb Perspect Biol. 2019 12 02; 11(12).
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Kim BJ, Kim Y, Hong EP, Jeon JP, Yang JS, Choi HJ, Kang SH, Cho YJ. Correlation Between Altered DNA Methylation of Intergenic Regions of ITPR3 and Development of Delayed Cerebral Ischemia in Patients with Subarachnoid Hemorrhage. World Neurosurg. 2019 Oct; 130:e449-e456.
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Wakai T, Fissore RA. Constitutive IP3R1-mediated Ca2+ release reduces Ca2+ store content and stimulates mitochondrial metabolism in mouse GV oocytes. J Cell Sci. 2019 02 12; 132(3).
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Acharya D, Hainer SJ, Yoon Y, Wang F, Bach I, Rivera-P?rez JA, Fazzio TG. KAT-Independent Gene Regulation by Tip60 Promotes ESC Self-Renewal but Not Pluripotency. Cell Rep. 2017 04 25; 19(4):671-679.
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Chen PB, Chen HV, Acharya D, Rando OJ, Fazzio TG. R loops regulate promoter-proximal chromatin architecture and cellular differentiation. Nat Struct Mol Biol. 2015 Dec; 22(12):999-1007.
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Croisier H, Tan X, Chen J, Sneyd J, Sanderson MJ, Brook BS. Ryanodine receptor sensitization results in abnormal calcium signaling in airway smooth muscle cells. Am J Respir Cell Mol Biol. 2015 Nov; 53(5):703-11.
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Zhang N, Yoon SY, Parys JB, Fissore RA. Effect of M-phase kinase phosphorylations on type 1 inositol 1,4,5-trisphosphate receptor-mediated Ca2+ responses in mouse eggs. Cell Calcium. 2015 Nov; 58(5):476-88.
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Zhang N, Fissore RA. Role of caspase-3 cleaved IP3 R1 on Ca(2+) homeostasis and developmental competence of mouse oocytes and eggs. J Cell Physiol. 2014 Nov; 229(11):1842-54.
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Cao P, Tan X, Donovan G, Sanderson MJ, Sneyd J. A deterministic model predicts the properties of stochastic calcium oscillations in airway smooth muscle cells. PLoS Comput Biol. 2014 Aug; 10(8):e1003783.
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Tan X, Sanderson MJ. Bitter tasting compounds dilate airways by inhibiting airway smooth muscle calcium oscillations and calcium sensitivity. Br J Pharmacol. 2014 Feb; 171(3):646-62.