Hepatocyte Nuclear Factor 4
"Hepatocyte Nuclear Factor 4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subfamily of nuclear receptors that regulate GENETIC TRANSCRIPTION of a diverse group of GENES involved in the synthesis of BLOOD COAGULATION FACTORS; and in GLUCOSE; CHOLESTEROL; and FATTY ACIDS metabolism.
| Descriptor ID |
D051557
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| MeSH Number(s) |
D12.776.260.262.968 D12.776.660.352.968 D12.776.826.119 D12.776.930.318.968
|
| Concept/Terms |
Hepatocyte Nuclear Factor 4- Hepatocyte Nuclear Factor 4
- Hepatocyte Nuclear Factor-Forkhead Homolog 4
- Hepatocyte Nuclear Factor Forkhead Homolog 4
- HNF4 Transcription Factor
- Transcription Factor, HNF4
|
Below are MeSH descriptors whose meaning is more general than "Hepatocyte Nuclear Factor 4".
Below are MeSH descriptors whose meaning is more specific than "Hepatocyte Nuclear Factor 4".
This graph shows the total number of publications written about "Hepatocyte Nuclear Factor 4" by people in this website by year, and whether "Hepatocyte Nuclear Factor 4" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Hepatocyte Nuclear Factor 4" by people in Profiles.
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Lei X, Ketelut-Carneiro N, Shmuel-Galia L, Xu W, Wilson R, Vierbuchen T, Chen Y, Reboldi A, Kang J, Edelblum KL, Ward D, Fitzgerald KA. Epithelial HNF4A shapes the intraepithelial lymphocyte compartment via direct regulation of immune signaling molecules. J Exp Med. 2022 08 01; 219(8).
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Palaria A, Angelo JR, Guertin TM, Mager J, Tremblay KD. Patterning of the hepato-pancreatobiliary boundary by BMP reveals heterogeneity within the murine liver bud. Hepatology. 2018 07; 68(1):274-288.
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Moore BD, Jin RU, Lo H, Jung M, Wang H, Battle MA, Wollheim CB, Urano F, Mills JC. Transcriptional Regulation of X-Box-binding Protein One (XBP1) by Hepatocyte Nuclear Factor 4a (HNF4?) Is Vital to Beta-cell Function. J Biol Chem. 2016 Mar 18; 291(12):6146-57.
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Shaw SY, Blodgett DM, Ma MS, Westly EC, Clemons PA, Subramanian A, Schreiber SL. Disease allele-dependent small-molecule sensitivities in blood cells from monogenic diabetes. Proc Natl Acad Sci U S A. 2011 Jan 11; 108(2):492-7.