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Inorganic phosphate blocks binding of pre-miRNA to Dicer-2 via its PAZ domain.
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Inorganic phosphate blocks binding of pre-miRNA to Dicer-2 via its PAZ domain.
Fukunaga R, Colpan C, Han BW, Zamore PD. Inorganic phosphate blocks binding of pre-miRNA to Dicer-2 via its PAZ domain. EMBO J. 2014 Feb 18; 33(4):371-84.
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PubMed
subject areas
Amino Acid Substitution
Animals
Arginine
Drosophila melanogaster
Drosophila Proteins
Female
MicroRNAs
Mutagenesis, Site-Directed
Phosphates
Protein Binding
Protein Structure, Tertiary
Recombinant Fusion Proteins
Ribonuclease III
RNA Helicases
RNA, Double-Stranded
Substrate Specificity
authors with profiles
Phillip D Zamore PhD