Histone Deacetylase 1

"Histone Deacetylase 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A histone deacetylase subtype that is found along with HISTONE DEACETYLASE 2; RETINOBLASTOMA-BINDING PROTEIN 4; and RETINOBLASTOMA-BINDING PROTEIN 7 as core components of histone deacetylase complexes.

Descriptor ID	D056284
MeSH Number(s)	D08.811.277.087.520.500.100 D08.811.277.087.520.750.100 D08.811.600.620.100 D08.811.600.795.100
Concept/Terms	Histone Deacetylase 1 Histone Deacetylase 1 Deacetylase 1, Histone HDAC1 Histone Deacetylase Deacetylase, HDAC1 Histone Histone Deacetylase, HDAC1 RPD3L1 Histone Deacetylase Deacetylase, RPD3L1 Histone Histone Deacetylase, RPD3L1

Below are MeSH descriptors whose meaning is more general than "Histone Deacetylase 1".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Hydrolases [D08.811.277]
Amidohydrolases [D08.811.277.087]
Histone Deacetylases [D08.811.277.087.520]
Mi-2 Nucleosome Remodeling and Deacetylase Complex [D08.811.277.087.520.500]
Histone Deacetylase 1 [D08.811.277.087.520.500.100]
Sin3 Histone Deacetylase and Corepressor Complex [D08.811.277.087.520.750]
Histone Deacetylase 1 [D08.811.277.087.520.750.100]
Multienzyme Complexes [D08.811.600]
Mi-2 Nucleosome Remodeling and Deacetylase Complex [D08.811.600.620]
Histone Deacetylase 1 [D08.811.600.620.100]
Sin3 Histone Deacetylase and Corepressor Complex [D08.811.600.795]
Histone Deacetylase 1 [D08.811.600.795.100]

Below are MeSH descriptors whose meaning is related to "Histone Deacetylase 1".

Below are MeSH descriptors whose meaning is more specific than "Histone Deacetylase 1".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Histone Deacetylase 1" by people in this website by year, and whether "Histone Deacetylase 1" was a major or minor topic of these publications.

Bar chart showing 6 publications over 5 distinct years, with a maximum of 2 publications in 2008

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2008	0	2	2
2010	0	1	1
2014	0	1	1
2017	1	0	1
2020	1	0	1

Below are the most recent publications written about "Histone Deacetylase 1" by people in Profiles.

Milstone ZJ, Saheera S, Bourke LM, Shpilka T, Haynes CM, Trivedi CM. Histone deacetylases 1 and 2 silence cryptic transcription to promote mitochondrial function during cardiogenesis. Sci Adv. 2020 04; 6(15):eaax5150.

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Milstone ZJ, Lawson G, Trivedi CM. Histone deacetylase 1 and 2 are essential for murine neural crest proliferation, pharyngeal arch development, and craniofacial morphogenesis. Dev Dyn. 2017 12; 246(12):1015-1026.

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Malonia SK, Yadav B, Sinha S, Lazennec G, Chattopadhyay S. Chromatin remodeling protein SMAR1 regulates NF-?B dependent Interleukin-8 transcription in breast cancer. Int J Biochem Cell Biol. 2014 Oct; 55:220-6.

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Jakovcevski M, Bharadwaj R, Straubhaar J, Gao G, Gavin DP, Jakovcevski I, Mitchell AC, Akbarian S. Prefrontal cortical dysfunction after overexpression of histone deacetylase 1. Biol Psychiatry. 2013 Nov 01; 74(9):696-705.

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Ali SA, Dobson JR, Lian JB, Stein JL, van Wijnen AJ, Zaidi SK, Stein GS. A RUNX2-HDAC1 co-repressor complex regulates rRNA gene expression by modulating UBF acetylation. J Cell Sci. 2012 Jun 01; 125(Pt 11):2732-9.

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Sinha S, Malonia SK, Mittal SP, Singh K, Kadreppa S, Kamat R, Mukhopadhyaya R, Pal JK, Chattopadhyay S. Coordinated regulation of p53 apoptotic targets BAX and PUMA by SMAR1 through an identical MAR element. EMBO J. 2010 Feb 17; 29(4):830-42.

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Choe SK, Lu P, Nakamura M, Lee J, Sagerstr?m CG. Meis cofactors control HDAC and CBP accessibility at Hox-regulated promoters during zebrafish embryogenesis. Dev Cell. 2009 Oct; 17(4):561-7.

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Kim D, Frank CL, Dobbin MM, Tsunemoto RK, Tu W, Peng PL, Guan JS, Lee BH, Moy LY, Giusti P, Broodie N, Mazitschek R, Delalle I, Haggarty SJ, Neve RL, Lu Y, Tsai LH. Deregulation of HDAC1 by p25/Cdk5 in neurotoxicity. Neuron. 2008 Dec 10; 60(5):803-17.

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Singh K, Sinha S, Malonia SK, Bist P, Tergaonkar V, Chattopadhyay S. Tumor suppressor SMAR1 represses IkappaBalpha expression and inhibits p65 transactivation through matrix attachment regions. J Biol Chem. 2009 Jan 09; 284(2):1267-78.

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Schroeder FA, Penta KL, Matevossian A, Jones SR, Konradi C, Tapper AR, Akbarian S. Drug-induced activation of dopamine D(1) receptor signaling and inhibition of class I/II histone deacetylase induce chromatin remodeling in reward circuitry and modulate cocaine-related behaviors. Neuropsychopharmacology. 2008 Nov; 33(12):2981-92.

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