Below are the most recent publications written about "Receptors, G-Protein-Coupled" by people in Profiles.
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Biswas K, Moore C, Rogers H, Wani KA, Mushtaq A, Pukkila-Worley R, Higgins DP, Walker AK, Mullen GP, Rand JB, Francis MM. Transcriptional responses to chronic oxidative stress require cholinergic activation of G-protein-coupled receptor signaling. Elife. 2026 Jun 08; 14.
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Bub L, Evren E, Verwaerde S, Ruscitti C, Vanneste D, Ghosh P, Gao Y, Sleiers N, Deng R, L?pez Montes M, Howley K, La Rocca R, Niehrs A, Glaros V, Reina-Campos M, Dahlen B, Smed-S?rensen A, Lund H, Kreslavsky T, Bj?rkstr?m NK, Reboldi A, Bossios A, Marichal T, Lambrecht BN, Willinger T. Sensing of metabolic signals via GPR183 promotes occupation of lung macrophage niches by monocytes. J Exp Med. 2026 Apr 06; 223(4).
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Chacon-Millan P, Delicato A, Mahmood A, Tirozzi A, Monfregola J, Duroure K, Serafini M, Kroll F, El-Hage O, Salah S, Atawneh OM, Atik T, Durmusalioglu EA, Isik E, Almontashiri NAM, Tabarki B, Kanaan M, Rabie G, Torella A, Spampanato C, Battaglia DI, Begemann A, Steindl K, Rauch A, Zweier M, Hajianpour M, Brigatti KW, Alhashem A, Maroofian R, Feigerlova E, Lambert L, Feillet F, Abbott MA, D'Alessio AM, Gonzaga-Jauregui C, Tawk M, De Matteis MA, Del Bene F, Zollino M, Nigro V, Venditti R, Franco B, Morleo M. Bi-allelic loss-of-function variants in JKAMP cause a neurodevelopmental syndrome associated with dysregulation of GPR37 trafficking. Am J Hum Genet. 2026 Mar 05; 113(3):562-581.
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Deng C, Zheng J, Xu F, Hong F, Zhan M, Chen Q, Peng Y, Cao Y, Xiao J, Liao Y, Xiao H, Song M. Processing-induced structural remodeling enhances the hypoglycemic activity of Polygonatum cyrtonema Hua polysaccharides via gut microbiota-SCFA-GPR41/43 pathway. Food Res Int. 2026 Apr 01; 229:118492.
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Tolomeo M, Magliocca V, Petrini S, Nisco A, Barbaro R, Lanza M, Piccione M, Giudetti AM, Massey K, Console L, Indiveri C, Zanier K, Bertini E, Persichini T, Compagnucci C, Colella M, Barile M. Altered dimerization of certain riboflavin transporter 2 mutants: a possible source of UPR, altered calcium signalling and mitochondrial derangements in RTD2. Arch Biochem Biophys. 2026 Jan; 775:110675.
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Miller BR, Gonzaga-Jauregui C, Brigatti KW, de Jong J, Breese RS, Ko SY, Puffenberger EG, Van Hout C, Young M, Luna VM, Staples J, First MB, Gregoire HJ, Dwork AJ, Pefanis E, McCarthy S, Brydges S, Rojas J, Ye B, Stahl E, Di Gioia SA, Hen R, Elwood K, Rosoklija G, Li D, Mellis S, Carey D, Croll SD, Overton JD, Macdonald LE, Economides AN, Shuldiner AR, Chuhma N, Rayport S, Amin N, Kushner SA, Alessandri-Haber N, Markx S, Strauss KA. A rare variant in GPR156 associated with depression in a Mennonite pedigree causes habenula hyperactivity and stress sensitivity in mice. Proc Natl Acad Sci U S A. 2025 Apr 22; 122(16):e2404754122.
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Jurgens EM, Firestone RS, Chaudhari J, Hosszu K, Devlin SM, Shah UA, Landa J, McAvoy DP, Lesokhin AM, Korde N, Hassoun H, Tan CR, Hultcrantz M, Shah GL, Landau HJ, Chung DJ, Scordo M, Eren OC, Dogan A, Giralt SA, Park JH, Rivi?re I, Brentjens RJ, Smith EL, Wang X, Usmani SZ, Mailankody S. Phase I Trial of MCARH109, a G Protein-Coupled Receptor Class C Group 5 Member D (GPRC5D)-Targeted Chimeric Antigen Receptor T-Cell Therapy for Multiple Myeloma: An Updated Analysis. J Clin Oncol. 2025 02 10; 43(5):498-504.
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Buckley M, Jacob WP, Bortey L, McClain ME, Ritter AL, Godfrey A, Munneke AS, Ramachandran S, Kenis S, Kolnik JC, Olofsson S, Nenadovich M, Kutoloski T, Rademacher L, Alva A, Heinecke O, Adkins R, Parkar S, Bhagat R, Lunato J, Beets I, Francis MM, Kowalski JR. Cell non-autonomous signaling through the conserved C. elegans glycoprotein hormone receptor FSHR-1 regulates cholinergic neurotransmission. PLoS Genet. 2024 Nov; 20(11):e1011461.
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Tse-Kang SY, Wani KA, Peterson ND, Page A, Humphries F, Pukkila-Worley R. Intestinal immunity in C.?elegans is activated by pathogen effector-triggered aggregation of the guard protein TIR-1 on lysosome-related organelles. Immunity. 2024 10 08; 57(10):2280-2295.e6.
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Tse-Kang SY, Pukkila-Worley R. Lysosome-related organelle integrity suppresses TIR-1 aggregation to restrain toxic propagation of p38 innate immunity. Cell Rep. 2024 09 24; 43(9):114674.