Receptor Protein-Tyrosine Kinases

"Receptor Protein-Tyrosine Kinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A class of cellular receptors that have an intrinsic PROTEIN-TYROSINE KINASE activity.

Descriptor ID	D020794
MeSH Number(s)	D08.811.913.696.620.682.725.400 D12.776.543.750.630
Concept/Terms	Receptor Protein-Tyrosine Kinases Receptor Protein-Tyrosine Kinases Kinases, Receptor Protein-Tyrosine Protein-Tyrosine Kinases, Receptor Receptor Protein Tyrosine Kinases Receptors, Protein-Tyrosine Kinase Protein-Tyrosine Kinase Receptors Receptors, Protein Tyrosine Kinase PTK Receptors Receptors, PTK Tyrosine Kinase Receptors Protein-Tyrosine Kinase Receptor Receptor, Protein-Tyrosine Kinase Receptor Protein-Tyrosine Kinase Kinase, Receptor Protein-Tyrosine Protein-Tyrosine Kinase, Receptor Receptor Protein Tyrosine Kinase Tyrosine Kinase Linked Receptors

Below are MeSH descriptors whose meaning is more general than "Receptor Protein-Tyrosine Kinases".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Transferases [D08.811.913]
Phosphotransferases [D08.811.913.696]
Phosphotransferases (Alcohol Group Acceptor) [D08.811.913.696.620]
Protein Kinases [D08.811.913.696.620.682]
Protein-Tyrosine Kinases [D08.811.913.696.620.682.725]
Receptor Protein-Tyrosine Kinases [D08.811.913.696.620.682.725.400]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Membrane Proteins [D12.776.543]
Receptors, Cell Surface [D12.776.543.750]
Receptor Protein-Tyrosine Kinases [D12.776.543.750.630]

Below are MeSH descriptors whose meaning is related to "Receptor Protein-Tyrosine Kinases".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Receptor Protein-Tyrosine Kinases" by people in this website by year, and whether "Receptor Protein-Tyrosine Kinases" was a major or minor topic of these publications.

Bar chart showing 45 publications over 24 distinct years, with a maximum of 4 publications in 2022

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1997	0	1	1
1999	1	0	1
2000	1	1	2
2001	2	1	3
2002	2	0	2
2004	0	1	1
2005	2	1	3
2006	1	1	2
2007	0	1	1
2008	1	1	2
2011	2	1	3
2012	1	1	2
2013	2	0	2
2014	3	0	3
2015	0	2	2
2016	2	0	2
2017	1	0	1
2018	0	1	1
2019	2	0	2
2022	1	3	4
2023	1	0	1
2024	0	1	1
2025	2	0	2
2026	1	0	1

Below are the most recent publications written about "Receptor Protein-Tyrosine Kinases" by people in Profiles.

Ribas CAPM, N Doelken E, Tripathi S, Polat B, Lissner R, B?eldicke T, Ribas-Filho JM, Malafaia O, Gasser M, Waaga-Gasser AM. Prognostic and predictive value of AXL and C-MET in patients with rectal cancer. Arq Bras Cir Dig. 2026; 38:e1918.

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Ravichandran KA, Brosseron F, McManus RM, Ising C, G?rgen S, Schmidt SV, Santarelli F, Lee SY, Jung H, Chung WS, Kim CH, Ruiz Laza A, Ruiz de Almod?var C, Ramirez A, Latz E, Heneka MT. Enhancing Tyro3 signaling ameliorates IL-1? production through STAT1 in Alzheimer's disease models. J Leukoc Biol. 2025 Dec 01; 117(12).

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Galgani A, Mary A, Lombardo F, Martini N, Scotto M, Tognoni G, Siciliano G, Ceravolo R, Giorgi FS, Heneka MT. Locus coeruleus integrity correlates with plasma soluble Axl levels in Alzheimer's disease patients. Alzheimers Dement. 2025 Jul; 21(7):e70434.

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Cocanougher BT, Liu SW, Francescatto L, Behura A, Anneling M, Jackson DG, Deak KL, Hornik CD, ElMallah MK, Pizoli CE, Smith EC, Tan KGQ, McDonald MT. The severity of MUSK pathogenic variants is predicted by the protein domain they disrupt. HGG Adv. 2024 Jul 18; 5(3):100288.

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Kim EJ, Reusch DB, Anthony H, Schmidt B, Corey K, Degar B, Huang JT. Disseminated juvenile xanthogranulomas with underlying neurotrophic tyrosine receptor kinase fusion and response to larotrectinib. Br J Dermatol. 2024 01 23; 190(2):283-284.

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Bharadwaj R, Anonick MV, Jaiswal S, Mashayekh S, Brown A, Wodzanowski KA, Okuda K, Silverman N, Grimes CL. Synthesis and validation of click-modified NOD1/2 agonists. Innate Immun. 2023 11; 29(8):186-200.

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Sentana-Lledo D, Viray H, Piper-Vallillo AJ, Widick P, Rangachari D, Wilson JL, Gangadharan SP, Aronovitz JA, Berman SM, VanderLaan PA, Costa DB. Complete pathologic response to short-course neoadjuvant alectinib in mediastinal node positive (N2) ALK rearranged lung cancer. Lung Cancer. 2022 10; 172:124-126.

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Caldwell TM, Ahn YM, Bulfer SL, Leary CB, Hood MM, Lu WP, Vogeti L, Vogeti S, Kaufman MD, Wise SC, Le Bourdonnec B, Smith BD, Flynn DL. Discovery of vimseltinib (DCC-3014), a highly selective CSF1R switch-control kinase inhibitor, in clinical development for the treatment of Tenosynovial Giant Cell Tumor (TGCT). Bioorg Med Chem Lett. 2022 10 15; 74:128928.

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Caldwell TM, Kaufman MD, Wise SC, Mi Ahn Y, Hood MM, Lu WP, Patt WC, Samarakoon T, Vogeti L, Vogeti S, Yates KM, Bulfer SL, Le Bourdonnec B, Smith BD, Flynn DL. Discovery of acyl ureas as highly selective small molecule CSF1R kinase inhibitors. Bioorg Med Chem Lett. 2022 10 15; 74:128929.

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Hemming ML, Benson MR, Loycano MA, Anderson JA, Andersen JL, Taddei ML, Krivtsov AV, Aubrey BJ, Cutler JA, Hatton C, Sicinska E, Armstrong SA. MOZ and Menin-MLL Complexes Are Complementary Regulators of Chromatin Association and Transcriptional Output in Gastrointestinal Stromal Tumor. Cancer Discov. 2022 07 06; 12(7):1804-1823.

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