Receptor for Advanced Glycation End Products

"Receptor for Advanced Glycation End Products" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A single-pass transmembrane CELL SURFACE RECEPTOR that binds ADVANCED GLYCATION END PRODUCTS to mediate cellular responses to both acute and chronic vascular inflammation in conditions such as ATHEROSCLEROSIS and DIABETES MELLITUS, TYPE 2. It also binds AMYLOID BETA PEPTIDES and the ALARMINS - S100A12 and S100 CALCIUM BINDING PROTEIN BETA SUBUNIT.

Descriptor ID	D000067759
MeSH Number(s)	D12.776.543.750.615
Concept/Terms	Receptor for Advanced Glycation End Products Receptor for Advanced Glycation End Products AGE Receptor Receptor, AGE RAGE (Receptor for Advanced Glycation End Products) Advanced Glycosylation End Product Receptors Advanced Glycosylation End-Product Receptor Advanced Glycosylation End Product Receptor Advanced Glycosylation End-Product Receptors Advanced Glycosylation Endproduct Receptors Receptor for Advanced Glycation End Products (RAGE) Receptor for Advanced Glycation Endproducts Receptor, Advanced Glycosylation End-Product Receptor, Advanced Glycosylation End Product Receptor, Advanced Glycosylation End-Products Receptor, Advanced Glycosylation End Products Advanced Glycosylation End Product-Specific Receptor Advanced Glycosylation End Product Specific Receptor AGER Protein Protein, AGER Amphoterin Receptor Receptor, Amphoterin

Below are MeSH descriptors whose meaning is more general than "Receptor for Advanced Glycation End Products".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Membrane Proteins [D12.776.543]
Receptors, Cell Surface [D12.776.543.750]
Receptor for Advanced Glycation End Products [D12.776.543.750.615]

Below are MeSH descriptors whose meaning is related to "Receptor for Advanced Glycation End Products".

Below are MeSH descriptors whose meaning is more specific than "Receptor for Advanced Glycation End Products".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Receptor for Advanced Glycation End Products" by people in this website by year, and whether "Receptor for Advanced Glycation End Products" was a major or minor topic of these publications.

Bar chart showing 15 publications over 11 distinct years, with a maximum of 3 publications in 2014

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1998	0	1	1
2001	0	1	1
2003	0	1	1
2004	0	1	1
2006	0	1	1
2007	2	0	2
2012	0	1	1
2013	0	1	1
2014	0	3	3
2016	1	0	1
2019	1	1	2

Below are the most recent publications written about "Receptor for Advanced Glycation End Products" by people in Profiles.

Hurtado Del Pozo C, Ruiz HH, Arivazhagan L, Aranda JF, Shim C, Daya P, Derk J, MacLean M, He M, Frye L, Friedline RH, Noh HL, Kim JK, Friedman RA, Ramasamy R, Schmidt AM. A Receptor of the Immunoglobulin Superfamily Regulates Adaptive Thermogenesis. Cell Rep. 2019 07 16; 28(3):773-791.e7.

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Celli BR, Anderson JA, Brook R, Calverley P, Cowans NJ, Crim C, Dixon I, Kim V, Martinez FJ, Morris A, Newby DE, Yates J, Vestbo J. Serum biomarkers and outcomes in patients with moderate COPD: a substudy of the randomised SUMMIT trial. BMJ Open Respir Res. 2019; 6(1):e000431.

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Bertheloot D, Naumovski AL, Langhoff P, Horvath GL, Jin T, Xiao TS, Garbi N, Agrawal S, Kolbeck R, Latz E. RAGE Enhances TLR Responses through Binding and Internalization of RNA. J Immunol. 2016 11 15; 197(10):4118-4126.

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Fassl SK, Austermann J, Papantonopoulou O, Riemenschneider M, Xue J, Bertheloot D, Freise N, Spiekermann C, Witten A, Viemann D, Kirschnek S, Stoll M, Latz E, Schultze JL, Roth J, Vogl T. Transcriptome assessment reveals a dominant role for TLR4 in the activation of human monocytes by the alarmin MRP8. J Immunol. 2015 Jan 15; 194(2):575-83.

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Martinez N, Vallerskog T, West K, Nunes-Alves C, Lee J, Martens GW, Behar SM, Kornfeld H. Chromatin decondensation and T cell hyperresponsiveness in diabetes-associated hyperglycemia. J Immunol. 2014 Nov 01; 193(9):4457-68.

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Song F, Hurtado del Pozo C, Rosario R, Zou YS, Ananthakrishnan R, Xu X, Patel PR, Benoit VM, Yan SF, Li H, Friedman RA, Kim JK, Ramasamy R, Ferrante AW, Schmidt AM. RAGE regulates the metabolic and inflammatory response to high-fat feeding in mice. Diabetes. 2014 Jun; 63(6):1948-65.

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Sirois CM, Jin T, Miller AL, Bertheloot D, Nakamura H, Horvath GL, Mian A, Jiang J, Schrum J, Bossaller L, Pelka K, Garbi N, Brewah Y, Tian J, Chang C, Chowdhury PS, Sims GP, Kolbeck R, Coyle AJ, Humbles AA, Xiao TS, Latz E. RAGE is a nucleic acid receptor that promotes inflammatory responses to DNA. J Exp Med. 2013 Oct 21; 210(11):2447-63.

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Albert DA, Ward A, Allweiss P, Graves DT, Knowler WC, Kunzel C, Leibel RL, Novak KF, Oates TW, Papapanou PN, Schmidt AM, Taylor GW, Lamster IB, Lalla E. Diabetes and oral disease: implications for health professionals. Ann N Y Acad Sci. 2012 May; 1255:1-15.

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Krieg AM. TLR9 and DNA 'feel' RAGE. Nat Immunol. 2007 May; 8(5):475-7.

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Tian J, Avalos AM, Mao SY, Chen B, Senthil K, Wu H, Parroche P, Drabic S, Golenbock D, Sirois C, Hua J, An LL, Audoly L, La Rosa G, Bierhaus A, Naworth P, Marshak-Rothstein A, Crow MK, Fitzgerald KA, Latz E, Kiener PA, Coyle AJ. Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE. Nat Immunol. 2007 May; 8(5):487-96.

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