Proto-Oncogene Proteins c-ret

"Proto-Oncogene Proteins c-ret" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Receptor protein-tyrosine kinases involved in the signaling of GLIAL CELL-LINE DERIVED NEUROTROPHIC FACTOR ligands. They contain an extracellular cadherin domain and form a receptor complexes with GDNF RECEPTORS. Mutations in ret protein are responsible for HIRSCHSPRUNG DISEASE and MULTIPLE ENDOCRINE NEOPLASIA TYPE 2.

Descriptor ID	D051096
MeSH Number(s)	D08.811.913.696.620.682.725.400.087 D12.776.395.550.200.188.500 D12.776.543.131.500 D12.776.543.750.630.217 D12.776.624.664.700.194
Concept/Terms	Proto-Oncogene Proteins c-ret Proto-Oncogene Proteins c-ret Proto Oncogene Proteins c ret c-ret, Proto-Oncogene Proteins Receptor Tyrosine Kinase RET ret Proto-Oncogene Proteins Proto-Oncogene Proteins, ret ret Proto Oncogene Proteins Proto-Oncogene Protein c-ret Proto Oncogene Protein c ret c-ret, Proto-Oncogene Protein c-ret Protein Proto-Oncogene Protein Ret Proto Oncogene Protein Ret Ret, Proto-Oncogene Protein

Below are MeSH descriptors whose meaning is more general than "Proto-Oncogene Proteins c-ret".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Transferases [D08.811.913]
Phosphotransferases [D08.811.913.696]
Phosphotransferases (Alcohol Group Acceptor) [D08.811.913.696.620]
Protein Kinases [D08.811.913.696.620.682]
Protein-Tyrosine Kinases [D08.811.913.696.620.682.725]
Receptor Protein-Tyrosine Kinases [D08.811.913.696.620.682.725.400]
Proto-Oncogene Proteins c-ret [D08.811.913.696.620.682.725.400.087]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Glycoproteins [D12.776.395]
Membrane Glycoproteins [D12.776.395.550]
Cell Adhesion Molecules [D12.776.395.550.200]
Cadherin Related Proteins [D12.776.395.550.200.188]
Proto-Oncogene Proteins c-ret [D12.776.395.550.200.188.500]
Membrane Proteins [D12.776.543]
Cadherin Related Proteins [D12.776.543.131]
Proto-Oncogene Proteins c-ret [D12.776.543.131.500]
Receptors, Cell Surface [D12.776.543.750]
Receptor Protein-Tyrosine Kinases [D12.776.543.750.630]
Proto-Oncogene Proteins c-ret [D12.776.543.750.630.217]
Neoplasm Proteins [D12.776.624]
Oncogene Proteins [D12.776.624.664]
Proto-Oncogene Proteins [D12.776.624.664.700]
Proto-Oncogene Proteins c-ret [D12.776.624.664.700.194]

Below are MeSH descriptors whose meaning is related to "Proto-Oncogene Proteins c-ret".

Below are MeSH descriptors whose meaning is more specific than "Proto-Oncogene Proteins c-ret".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Proto-Oncogene Proteins c-ret" by people in this website by year, and whether "Proto-Oncogene Proteins c-ret" was a major or minor topic of these publications.

Bar chart showing 7 publications over 5 distinct years, with a maximum of 3 publications in 2016

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2006	1	0	1
2011	0	1	1
2015	0	1	1
2016	1	2	3
2022	0	1	1

Below are the most recent publications written about "Proto-Oncogene Proteins c-ret" by people in Profiles.

Estrada-Zuniga CM, Cheng ZM, Ethiraj P, Guo Q, Gonzalez-Cant? H, Adderley E, Lopez H, Landry BN, Zainal A, Aronin N, Ding Y, Wang X, Aguiar RCT, Dahia PLM. A RET::GRB2 fusion in pheochromocytoma defies the classic paradigm of RET oncogenic fusions. Cell Rep Med. 2022 07 19; 3(7):100686.

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Lawrence NF, Hammond MR, Frederick DT, Su Y, Dias-Santagata D, Deng A, Selim MA, Mahalingam M, Flaherty KT, Hoang MP. Ki-67, p53, and p16 expression, and G691S RET polymorphism in desmoplastic melanoma (DM): A clinicopathologic analysis of predictors of outcome. J Am Acad Dermatol. 2016 Sep; 75(3):595-602.

View in: PubMed
Bogunovic M. ILC3s and the Willow Tree of Voices. Immunity. 2016 08 16; 45(2):238-9.

View in: PubMed
Kadokura A, Frydenlund N, Leone DA, Yang S, Hoang MP, Deng A, Hernandez-Perez M, Biswas A, Singh R, Yaar R, Mahalingam M. Neurofibromin protein loss in desmoplastic melanoma subtypes: implicating NF1 allelic loss as a distinct genetic driver? Hum Pathol. 2016 07; 53:82-90.

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Frydenlund N, Leone DA, Mitchell B, Yang S, Deng A, Hoang MP, Mahalingam M. Neurotrophin receptors and perineural invasion in desmoplastic melanoma. J Am Acad Dermatol. 2015 May; 72(5):851-8.

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Miller DD, Emley A, Yang S, Richards JE, Lee JE, Deng A, Hoang MP, Mahalingam M. Mixed versus pure variants of desmoplastic melanoma: a genetic and immunohistochemical appraisal. Mod Pathol. 2012 Apr; 25(4):505-15.

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Karim S, Hession C, Marconi S, Gang DL, Otis CN. The identification of ganglion cells in Hirschsprung disease by the immunohistochemical detection of ret oncoprotein. Am J Clin Pathol. 2006 Jul; 126(1):49-54.

View in: PubMed

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