"Receptor, Notch4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A notch receptor and proto-oncogene protein characterized by a large extracellular domain that consists of 29 EPIDERMAL GROWTH FACTOR - like repeat sequences (EGF repeats) and five ANKYRIN REPEATS. It functions as a receptor for SERRATE-JAGGED PROTEINS and Delta1 (DLK1) protein to control cell fate determination.
| Descriptor ID |
D000074562
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| MeSH Number(s) |
D12.776.543.750.725.937 D12.776.624.664.700.815 D12.776.930.770.937
|
| Concept/Terms |
Receptor, Notch4- Receptor, Notch4
- Notch4 Receptor
- Notch4 Protein
- Notch-4 Protein
- Notch 4 Protein
- Notch-4 Receptor
- Notch 4 Receptor
- Receptor, Notch-4
|
Below are MeSH descriptors whose meaning is more general than "Receptor, Notch4".
Below are MeSH descriptors whose meaning is more specific than "Receptor, Notch4".
This graph shows the total number of publications written about "Receptor, Notch4" by people in this website by year, and whether "Receptor, Notch4" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 |
| 2008 | 0 | 2 | 2 |
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Below are the most recent publications written about "Receptor, Notch4" by people in Profiles.
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Joshi I, Minter LM, Telfer J, Demarest RM, Capobianco AJ, Aster JC, Sicinski P, Fauq A, Golde TE, Osborne BA. Notch signaling mediates G1/S cell-cycle progression in T cells via cyclin D3 and its dependent kinases. Blood. 2009 Feb 19; 113(8):1689-98.
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Song LL, Peng Y, Yun J, Rizzo P, Chaturvedi V, Weijzen S, Kast WM, Stone PJ, Santos L, Loredo A, Lendahl U, Sonenshein G, Osborne B, Qin JZ, Pannuti A, Nickoloff BJ, Miele L. Notch-1 associates with IKKalpha and regulates IKK activity in cervical cancer cells. Oncogene. 2008 Oct 02; 27(44):5833-44.
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Carlson TR, Yan Y, Wu X, Lam MT, Tang GL, Beverly LJ, Messina LM, Capobianco AJ, Werb Z, Wang R. Endothelial expression of constitutively active Notch4 elicits reversible arteriovenous malformations in adult mice. Proc Natl Acad Sci U S A. 2005 Jul 12; 102(28):9884-9.