"Kruppel-Like Factor 6" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A Kruppel-like transcription factor that contains three C-terminal CYS2-HIS2 ZINC FINGERS and binds to GC RICH SEQUENCE (GC box) in upstream gene promoters. It functions as a transcriptional activator, tumor suppressor, and may regulate growth and development of B-cells.
| Descriptor ID |
D000075723
|
| MeSH Number(s) |
D12.776.260.522.563 D12.776.260.755.050 D12.776.624.664.700.120 D12.776.930.375.563
|
| Concept/Terms |
Kruppel-Like Factor 6- Kruppel-Like Factor 6
- Kruppel Like Factor 6
- CPBP Protein
- Core Promoter Element Binding Protein
- COPEB Protein
|
Below are MeSH descriptors whose meaning is more general than "Kruppel-Like Factor 6".
Below are MeSH descriptors whose meaning is more specific than "Kruppel-Like Factor 6".
This graph shows the total number of publications written about "Kruppel-Like Factor 6" by people in this website by year, and whether "Kruppel-Like Factor 6" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Kruppel-Like Factor 6" by people in Profiles.
-
Ahronian LG, Zhu LJ, Chen YW, Chu HC, Klimstra DS, Lewis BC. A novel KLF6-Rho GTPase axis regulates hepatocellular carcinoma cell migration and dissemination. Oncogene. 2016 09 01; 35(35):4653-62.
-
Sangodkar J, DiFeo A, Feld L, Bromberg R, Schwartz R, Huang F, Terzo EA, Choudhri A, Narla G. Targeted reduction of KLF6-SV1 restores chemotherapy sensitivity in resistant lung adenocarcinoma. Lung Cancer. 2009 Dec; 66(3):292-7.
-
DiFeo A, Feld L, Rodriguez E, Wang C, Beer DG, Martignetti JA, Narla G. A functional role for KLF6-SV1 in lung adenocarcinoma prognosis and chemotherapy response. Cancer Res. 2008 Feb 15; 68(4):965-70.