Frizzled Receptors

"Frizzled Receptors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A family of seven-pass transmembrane cell-surface proteins that combines with LOW DENSITY LIPROTEIN RECEPTOR-RELATED PROTEIN-5 or LOW DENSITY LIPROTEIN RECEPTOR-RELATED PROTEIN-5 to form receptors for WNT PROTEINS. Frizzled receptors often couple with HETEROTRIMERIC G PROTEINS and regulate the WNT SIGNALING PATHWAY.

Descriptor ID	D051157
MeSH Number(s)	D12.776.543.750.695.017 D12.776.543.750.850.500
Concept/Terms	Frizzled Receptors Frizzled Receptors Frizzled Receptor Receptor, Frizzled Receptors, Frizzled Frizzled Proteins

Below are MeSH descriptors whose meaning is more general than "Frizzled Receptors".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Membrane Proteins [D12.776.543]
Receptors, Cell Surface [D12.776.543.750]
Receptors, G-Protein-Coupled [D12.776.543.750.695]
Frizzled Receptors [D12.776.543.750.695.017]
Receptors, Wnt [D12.776.543.750.850]
Frizzled Receptors [D12.776.543.750.850.500]

Below are MeSH descriptors whose meaning is related to "Frizzled Receptors".

Below are MeSH descriptors whose meaning is more specific than "Frizzled Receptors".

Frizzled Receptors
Smoothened Receptor

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Frizzled Receptors" by people in this website by year, and whether "Frizzled Receptors" was a major or minor topic of these publications.

Bar chart showing 9 publications over 9 distinct years, with a maximum of 1 publications in 1997 and 2000 and 2005 and 2006 and 2007 and 2009 and 2012 and 2015 and 2023

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1997	0	1	1
2000	0	1	1
2005	0	1	1
2006	1	0	1
2007	0	1	1
2009	0	1	1
2012	1	0	1
2015	1	0	1
2023	0	1	1

Below are the most recent publications written about "Frizzled Receptors" by people in Profiles.

Gayden J, Hu S, Joseph PN, Delgado E, Liu S, Bell A, Puig S, Monga SP, Freyberg Z. A Spatial Atlas of Wnt Receptors in Adult Mouse Liver. Am J Pathol. 2023 05; 193(5):558-566.

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Tao L, Zhang J, Meraner P, Tovaglieri A, Wu X, Gerhard R, Zhang X, Stallcup WB, Miao J, He X, Hurdle JG, Breault DT, Brass AL, Dong M. Frizzled proteins are colonic epithelial receptors for C. difficile toxin B. Nature. 2016 Oct 20; 538(7625):350-355.

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Boyd JL, Skove SL, Rouanet JP, Pilaz LJ, Bepler T, Gord?n R, Wray GA, Silver DL. Human-chimpanzee differences in a FZD8 enhancer alter cell-cycle dynamics in the developing neocortex. Curr Biol. 2015 Mar 16; 25(6):772-779.

View in: PubMed
Speese SD, Ashley J, Jokhi V, Nunnari J, Barria R, Li Y, Ataman B, Koon A, Chang YT, Li Q, Moore MJ, Budnik V. Nuclear envelope budding enables large ribonucleoprotein particle export during synaptic Wnt signaling. Cell. 2012 May 11; 149(4):832-46.

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Korkut C, Ataman B, Ramachandran P, Ashley J, Barria R, Gherbesi N, Budnik V. Trans-synaptic transmission of vesicular Wnt signals through Evi/Wntless. Cell. 2009 Oct 16; 139(2):393-404.

View in: PubMed
Speese SD, Budnik V. Wnts: up-and-coming at the synapse. Trends Neurosci. 2007 Jun; 30(6):268-75.

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Ataman B, Ashley J, Gorczyca D, Gorczyca M, Mathew D, Wichmann C, Sigrist SJ, Budnik V. Nuclear trafficking of Drosophila Frizzled-2 during synapse development requires the PDZ protein dGRIP. Proc Natl Acad Sci U S A. 2006 May 16; 103(20):7841-6.

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Mathew D, Ataman B, Chen J, Zhang Y, Cumberledge S, Budnik V. Wingless signaling at synapses is through cleavage and nuclear import of receptor DFrizzled2. Science. 2005 Nov 25; 310(5752):1344-7.

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Gao FB, Kohwi M, Brenman JE, Jan LY, Jan YN. Control of dendritic field formation in Drosophila: the roles of flamingo and competition between homologous neurons. Neuron. 2000 Oct; 28(1):91-101.

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Rocheleau CE, Downs WD, Lin R, Wittmann C, Bei Y, Cha YH, Ali M, Priess JR, Mello CC. Wnt signaling and an APC-related gene specify endoderm in early C. elegans embryos. Cell. 1997 Aug 22; 90(4):707-16.

View in: PubMed

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