Receptors, Corticotropin-Releasing Hormone

"Receptors, Corticotropin-Releasing Hormone" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Cell surface proteins that bind corticotropin-releasing hormone with high affinity and trigger intracellular changes which influence the behavior of cells. The corticotropin releasing-hormone receptors on anterior pituitary cells mediate the stimulation of corticotropin release by hypothalamic corticotropin releasing factor. The physiological consequence of activating corticotropin-releasing hormone receptors on central neurons is not well understood.

Descriptor ID	D018019
MeSH Number(s)	D12.776.543.750.695.180 D12.776.543.750.720.600.290 D12.776.543.750.750.555.290 D12.776.543.750.750.700.150
Concept/Terms	Receptors, Corticotropin-Releasing Hormone Receptors, Corticotropin-Releasing Hormone Corticotropin-Releasing Hormone Receptors Hormone Receptors, Corticotropin-Releasing Receptors, Corticotropin Releasing Hormone Corticotropin Releasing-Hormone Receptors Corticotropin Releasing Hormone Receptors Receptors, Corticotropin Releasing-Hormone Releasing-Hormone Receptors, Corticotropin CRF Receptors Corticotropin Releasing-Factor Receptors Corticotropin Releasing Factor Receptors Receptors, Corticotropin Releasing-Factor Releasing-Factor Receptors, Corticotropin Receptors, CRF CRH Receptor Receptor, CRH CRH Receptors Receptors, CRH Corticotropin Releasing-Hormone Receptor Corticotropin Releasing Hormone Receptor Receptor, Corticotropin Releasing-Hormone Releasing-Hormone Receptor, Corticotropin CRF Receptor Receptor, CRF

Below are MeSH descriptors whose meaning is more general than "Receptors, Corticotropin-Releasing Hormone".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Membrane Proteins [D12.776.543]
Receptors, Cell Surface [D12.776.543.750]
Receptors, G-Protein-Coupled [D12.776.543.750.695]
Receptors, Corticotropin-Releasing Hormone [D12.776.543.750.695.180]
Receptors, Neurotransmitter [D12.776.543.750.720]
Receptors, Neuropeptide [D12.776.543.750.720.600]
Receptors, Corticotropin-Releasing Hormone [D12.776.543.750.720.600.290]
Receptors, Peptide [D12.776.543.750.750]
Receptors, Neuropeptide [D12.776.543.750.750.555]
Receptors, Corticotropin-Releasing Hormone [D12.776.543.750.750.555.290]
Receptors, Pituitary Hormone-Regulating Hormone [D12.776.543.750.750.700]
Receptors, Corticotropin-Releasing Hormone [D12.776.543.750.750.700.150]

Below are MeSH descriptors whose meaning is related to "Receptors, Corticotropin-Releasing Hormone".

Below are MeSH descriptors whose meaning is more specific than "Receptors, Corticotropin-Releasing Hormone".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Receptors, Corticotropin-Releasing Hormone" by people in this website by year, and whether "Receptors, Corticotropin-Releasing Hormone" was a major or minor topic of these publications.

Bar chart showing 20 publications over 12 distinct years, with a maximum of 4 publications in 2015

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2005	1	0	1
2006	0	1	1
2007	2	0	2
2008	3	0	3
2009	1	0	1
2010	0	1	1
2011	1	0	1
2012	0	1	1
2013	0	1	1
2015	2	2	4
2016	1	2	3
2017	1	0	1

Below are the most recent publications written about "Receptors, Corticotropin-Releasing Hormone" by people in Profiles.

Pomrenze MB, Fetterly TL, Winder DG, Messing RO. The Corticotropin Releasing Factor Receptor 1 in Alcohol Use Disorder: Still a Valid Drug Target? Alcohol Clin Exp Res. 2017 Dec; 41(12):1986-1999.

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Schreiber AL, Lu YL, Baynes BB, Richardson HN, Gilpin NW. Corticotropin-releasing factor in ventromedial prefrontal cortex mediates avoidance of a traumatic stress-paired context. Neuropharmacology. 2017 02; 113(Pt A):323-330.

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Itoga CA, Roltsch Hellard EA, Whitaker AM, Lu YL, Schreiber AL, Baynes BB, Baiamonte BA, Richardson HN, Gilpin NW. Traumatic Stress Promotes Hyperalgesia via Corticotropin-Releasing Factor-1 Receptor (CRFR1) Signaling in Central Amygdala. Neuropsychopharmacology. 2016 09; 41(10):2463-72.

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Linnstaedt SD, Bortsov AV, Soward AC, Swor R, Peak DA, Jones J, Rathlev N, Lee DC, Domeier R, Hendry PL, McLean SA. CRHBP polymorphisms predict chronic pain development following motor vehicle collision. Pain. 2016 Jan; 157(1):273-279.

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Silberman Y, Fetterly TL, Awad EK, Milano EJ, Usdin TB, Winder DG. Ethanol produces corticotropin-releasing factor receptor-dependent enhancement of spontaneous glutamatergic transmission in the mouse central amygdala. Alcohol Clin Exp Res. 2015 Nov; 39(11):2154-62.

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Zhao-Shea R, DeGroot SR, Liu L, Vallaster M, Pang X, Su Q, Gao G, Rando OJ, Martin GE, George O, Gardner PD, Tapper AR. Increased CRF signalling in a ventral tegmental area-interpeduncular nucleus-medial habenula circuit induces anxiety during nicotine withdrawal. Nat Commun. 2015 Apr 21; 6:6770.

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Silberman Y, Winder DG. Ethanol and corticotropin releasing factor receptor modulation of central amygdala neurocircuitry: An update and future directions. Alcohol. 2015 May; 49(3):179-84.

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Logan RW, Wynne O, Maglakelidze G, Zhang C, O'Connell S, Boyadjieva NI, Sarkar DK. ?-Endorphin neuronal transplantation into the hypothalamus alters anxiety-like behaviors in prenatal alcohol-exposed rats and alcohol-non-preferring and alcohol-preferring rats. Alcohol Clin Exp Res. 2015 Jan; 39(1):146-57.

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Silberman Y, Winder DG. Corticotropin releasing factor and catecholamines enhance glutamatergic neurotransmission in the lateral subdivision of the central amygdala. Neuropharmacology. 2013 Jul; 70:316-23.

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Conrad KL, Davis AR, Silberman Y, Sheffler DJ, Shields AD, Saleh SA, Sen N, Matthies HJ, Javitch JA, Lindsley CW, Winder DG. Yohimbine depresses excitatory transmission in BNST and impairs extinction of cocaine place preference through orexin-dependent, norepinephrine-independent processes. Neuropsychopharmacology. 2012 Sep; 37(10):2253-66.

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