Receptors, Formyl Peptide
"Receptors, Formyl Peptide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of G-protein-coupled receptors that was originally identified by its ability to bind N-formyl peptides such as N-FORMYLMETHIONINE LEUCYL-PHENYLALANINE. Since N-formyl peptides are found in MITOCHONDRIA and BACTERIA, this class of receptors is believed to play a role in mediating cellular responses to cellular damage and bacterial invasion. However, non-formylated peptide ligands have also been found for this receptor class.
| Descriptor ID |
D044042
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| MeSH Number(s) |
D12.776.543.750.695.235 D12.776.543.750.705.873 D12.776.543.750.750.340
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| Concept/Terms |
Receptors, Formyl Peptide- Receptors, Formyl Peptide
- Formyl Peptide Receptors
- Peptide Receptors, Formyl
- FMLP Receptor
- Receptor, FMLP
- N-formyl Hexapeptide Receptor
- Hexapeptide Receptor, N-formyl
- N formyl Hexapeptide Receptor
- Receptor, N-formyl Hexapeptide
- N-Formylmethionyl Peptide Receptor
- N Formylmethionyl Peptide Receptor
- Peptide Receptor, N-Formylmethionyl
- Receptor, N-Formylmethionyl Peptide
- fMet-Leu-Phe Receptor
- Receptor, fMet-Leu-Phe
- fMet Leu Phe Receptor
- Formyl Peptide Receptor
- Receptor, Formyl Peptide
- Receptor, Chemotactic Peptide
- Chemotactic Peptide Receptor
- Peptide Receptor, Chemotactic
- F-Chemotactic Peptide Receptor
- F Chemotactic Peptide Receptor
- Receptor, F-Chemotactic Peptide
- Chemoattractant Receptor
- Receptor, Chemoattractant
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Below are MeSH descriptors whose meaning is more general than "Receptors, Formyl Peptide".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Formyl Peptide".
This graph shows the total number of publications written about "Receptors, Formyl Peptide" by people in this website by year, and whether "Receptors, Formyl Peptide" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Receptors, Formyl Peptide" by people in Profiles.
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Burstein S. Molecular Mechanisms for the Inflammation-Resolving Actions of Lenabasum. Mol Pharmacol. 2021 02; 99(2):125-132.
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Schr?der N, Schaffrath A, Welter JA, Putzka T, Griep A, Ziegler P, Brandt E, Samer S, Heneka MT, Kaddatz H, Zhan J, Kipp E, Pufe T, Tauber SC, Kipp M, Brandenburg LO. Inhibition of formyl peptide receptors improves the outcome in a mouse model of Alzheimer disease. J Neuroinflammation. 2020 Apr 24; 17(1):131.
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Morris S, Vachani A, Pass HI, Rom WN, Ryden K, Weiss GJ, Hogarth DK, Runger G, Richards D, Shelton T, Mallery DW. Whole blood FPR1 mRNA expression predicts both non-small cell and small cell lung cancer. Int J Cancer. 2018 06 01; 142(11):2355-2362.
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McCormick BA, Parkos CA, Colgan SP, Carnes DK, Madara JL. Apical secretion of a pathogen-elicited epithelial chemoattractant activity in response to surface colonization of intestinal epithelia by Salmonella typhimurium. J Immunol. 1998 Jan 01; 160(1):455-66.
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Georgilis K, Klempner MS. In vitro effects of omega-3 fatty acids on neutrophil intracellular calcium homeostasis and receptor expression for FMLP and LTB4. Inflammation. 1988 Oct; 12(5):475-90.
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Borish L, O'Reilly D, Klempner MS, Rocklin RE. Leukocyte inhibitory factor (LIF) potentiates neutrophil responses to formyl-methionyl-leucyl-phenylalanine. J Immunol. 1986 Sep 15; 137(6):1897-903.
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Styrt B, Rocklin RE, Klempner MS. Inhibition of neutrophil superoxide production by fanetizole. Inflammation. 1985 Sep; 9(3):233-44.