L-Lactate Dehydrogenase

"L-Lactate Dehydrogenase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A tetrameric enzyme that, along with the coenzyme NAD+, catalyzes the interconversion of LACTATE and PYRUVATE. In vertebrates, genes for three different subunits (LDH-A, LDH-B and LDH-C) exist.

Descriptor ID	D007770
MeSH Number(s)	D08.811.682.047.551.400 D08.811.682.047.820.493
Concept/Terms	L-Lactate Dehydrogenase L-Lactate Dehydrogenase Dehydrogenase, L-Lactate L Lactate Dehydrogenase Lactate Dehydrogenase Dehydrogenase, Lactate

Below are MeSH descriptors whose meaning is more general than "L-Lactate Dehydrogenase".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Oxidoreductases [D08.811.682]
Alcohol Oxidoreductases [D08.811.682.047]
Lactate Dehydrogenases [D08.811.682.047.551]
L-Lactate Dehydrogenase [D08.811.682.047.551.400]
NAD (+) and NADP (+) Dependent Alcohol Oxidoreductases [D08.811.682.047.820]
L-Lactate Dehydrogenase [D08.811.682.047.820.493]

Below are MeSH descriptors whose meaning is related to "L-Lactate Dehydrogenase".

Below are MeSH descriptors whose meaning is more specific than "L-Lactate Dehydrogenase".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "L-Lactate Dehydrogenase" by people in this website by year, and whether "L-Lactate Dehydrogenase" was a major or minor topic of these publications.

Bar chart showing 20 publications over 13 distinct years, with a maximum of 3 publications in 2012 and 2013

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	1	1	2
1996	0	2	2
1998	0	1	1
1999	0	1	1
2007	0	1	1
2008	0	1	1
2010	0	2	2
2012	1	2	3
2013	0	3	3
2015	0	1	1
2022	0	1	1
2023	0	1	1
2024	1	0	1

Below are the most recent publications written about "L-Lactate Dehydrogenase" by people in Profiles.

Fu A. Reconsidering lactate disallowance in pancreatic ? cells. Trends Endocrinol Metab. 2024 Dec; 35(12):1023-1025.

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Pan CX, Lau WC, Kim DY, Lau CB, Rowley R, Kanwar R, LeBoeuf NR, Nambudiri VE. Association between baseline lactate dehydrogenase and immune-related adverse events among patients with melanoma varies by tumor stage at immune checkpoint inhibitor initiation. J Am Acad Dermatol. 2023 12; 89(6):1264-1268.

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Notarangelo G, Spinelli JB, Perez EM, Baker GJ, Kurmi K, Elia I, Stopka SA, Baquer G, Lin JR, Golby AJ, Joshi S, Baron HF, Drijvers JM, Georgiev P, Ringel AE, Zaganjor E, McBrayer SK, Sorger PK, Sharpe AH, Wucherpfennig KW, Santagata S, Agar NYR, Suv? ML, Haigis MC. Oncometabolite d-2HG alters T cell metabolism to impair CD8+ T cell function. Science. 2022 09 30; 377(6614):1519-1529.

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Barbosa LA, Fiuza PP, Borges LJ, Rolim FA, Andrade MB, Luz NF, Quintela-Carvalho G, Lima JB, Almeida RP, Chan FK, Bozza MT, Borges VM, Prates DB. RIPK1-RIPK3-MLKL-Associated Necroptosis Drives Leishmania infantum Killing in Neutrophils. Front Immunol. 2018; 9:1818.

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Tirabassi JN, Olewinski L, Khodaee M. Variation of Traditional Biomarkers of Liver Injury After an Ultramarathon at Altitude. Sports Health. 2018 Jul-Aug; 10(4):361-365.

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Kurtz DM, Green MR, Bratman SV, Scherer F, Liu CL, Kunder CA, Takahashi K, Glover C, Keane C, Kihira S, Visser B, Callahan J, Kong KA, Faham M, Corbelli KS, Miklos D, Advani RH, Levy R, Hicks RJ, Hertzberg M, Ohgami RS, Gandhi MK, Diehn M, Alizadeh AA. Noninvasive monitoring of diffuse large B-cell lymphoma by immunoglobulin high-throughput sequencing. Blood. 2015 Jun 11; 125(24):3679-87.

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Kapur NK, Vest AR, Cook J, Kiernan MS. Pump Thrombosis: A Limitation of Contemporary Left Ventricular Assist Devices. Curr Probl Cardiol. 2015 Dec; 40(12):511-40.

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Mirowsky J, Hickey C, Horton L, Blaustein M, Galdanes K, Peltier RE, Chillrud S, Chen LC, Ross J, Nadas A, Lippmann M, Gordon T. The effect of particle size, location and season on the toxicity of urban and rural particulate matter. Inhal Toxicol. 2013 Nov; 25(13):747-57.

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Pirela S, Molina R, Watson C, Cohen JM, Bello D, Demokritou P, Brain J. Effects of copy center particles on the lungs: a toxicological characterization using a Balb/c mouse model. Inhal Toxicol. 2013 Aug; 25(9):498-508.

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Dixen K, Basse AL, Murholm M, Isidor MS, Hansen LH, Petersen MC, Madsen L, Petrovic N, Nedergaard J, Quistorff B, Hansen JB. ERR? enhances UCP1 expression and fatty acid oxidation in brown adipocytes. Obesity (Silver Spring). 2013 Mar; 21(3):516-24.

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