Receptor, Cannabinoid, CB1
"Receptor, Cannabinoid, CB1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subclass of cannabinoid receptor found primarily on central and peripheral NEURONS where it may play a role modulating NEUROTRANSMITTER release.
| Descriptor ID |
D043884
|
| MeSH Number(s) |
D12.776.543.750.695.125.100
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Receptor, Cannabinoid, CB1".
Below are MeSH descriptors whose meaning is more specific than "Receptor, Cannabinoid, CB1".
This graph shows the total number of publications written about "Receptor, Cannabinoid, CB1" by people in this website by year, and whether "Receptor, Cannabinoid, CB1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 1 | 0 | 1 |
| 2014 | 2 | 0 | 2 |
| 2016 | 1 | 0 | 1 |
| 2017 | 4 | 0 | 4 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Receptor, Cannabinoid, CB1" by people in Profiles.
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Tahtouh T, Durieu E, Villiers B, Bruyère C, Nguyen TL, Fant X, Ahn KH, Khurana L, Deau E, Lindberg MF, Sévère E, Miege F, Roche D, Limanton E, L'Helgoual'ch JM, Burgy G, Guiheneuf S, Herault Y, Kendall DA, Carreaux F, Bazureau JP, Meijer L. Structure-Activity Relationship in the Leucettine Family of Kinase Inhibitors. J Med Chem. 2022 01 27; 65(2):1396-1417.
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Jourdan T, Nicoloro SM, Zhou Z, Shen Y, Liu J, Coffey NJ, Cinar R, Godlewski G, Gao B, Aouadi M, Czech MP, Kunos G. Decreasing CB1 receptor signaling in Kupffer cells improves insulin sensitivity in obese mice. Mol Metab. 2017 11; 6(11):1517-1528.
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Khurana L, Mackie K, Piomelli D, Kendall DA. Modulation of CB1 cannabinoid receptor by allosteric ligands: Pharmacology and therapeutic opportunities. Neuropharmacology. 2017 Sep 15; 124:3-12.
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Khurana L, Fu BQ, Duddupudi AL, Liao YH, Immadi SS, Kendall DA, Lu D. Pyrimidinyl Biphenylureas: Identification of New Lead Compounds as Allosteric Modulators of the Cannabinoid Receptor CB1. J Med Chem. 2017 02 09; 60(3):1089-1104.
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Jourdan T, Szanda G, Cinar R, Godlewski G, Holovac DJ, Park JK, Nicoloro S, Shen Y, Liu J, Rosenberg AZ, Liu Z, Czech MP, Kunos G. Developmental Role of Macrophage Cannabinoid-1 Receptor Signaling in Type 2 Diabetes. Diabetes. 2017 04; 66(4):994-1007.
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Shim JY, Khurana L, Kendall DA. Computational analysis of the CB1 carboxyl-terminus in the receptor-G protein complex. Proteins. 2016 Apr; 84(4):532-43.
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Tepper MA, Zurier RB, Burstein SH. Ultrapure ajulemic acid has improved CB2 selectivity with reduced CB1 activity. Bioorg Med Chem. 2014 Jul 01; 22(13):3245-51.
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Khurana L, Ali HI, Olszewska T, Ahn KH, Damaraju A, Kendall DA, Lu D. Optimization of chemical functionalities of indole-2-carboxamides to improve allosteric parameters for the cannabinoid receptor 1 (CB1). J Med Chem. 2014 Apr 10; 57(7):3040-52.
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Yu W, Calos M, Pilitsis J, Shin DS. Deconstructing the neural and ionic involvement of seizure-like events in the striatal network. Neurobiol Dis. 2013 Apr; 52:128-36.
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Kattamuri PV, Salmonsen R, McQuain C, Burstein S, Sun H, Li G. Asymmetric synthesis of novel N-(1-phenyl-2,3-dihydroxypropyl)arachidonylamides and evaluation of their anti-inflammatory activity. Life Sci. 2013 Mar 19; 92(8-9):506-11.