Receptor, Cannabinoid, CB1

"Receptor, Cannabinoid, CB1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A subclass of cannabinoid receptor found primarily on central and peripheral NEURONS where it may play a role modulating NEUROTRANSMITTER release.

Descriptor ID	D043884
MeSH Number(s)	D12.776.543.750.695.125.100
Concept/Terms	Receptor, Cannabinoid, CB1 Receptor, Cannabinoid, CB1 CB1 Receptor Receptor, CB1 Cannabinoid Receptor CB1 Receptor CB1, Cannabinoid

Below are MeSH descriptors whose meaning is more general than "Receptor, Cannabinoid, CB1".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Membrane Proteins [D12.776.543]
Receptors, Cell Surface [D12.776.543.750]
Receptors, G-Protein-Coupled [D12.776.543.750.695]
Receptors, Cannabinoid [D12.776.543.750.695.125]
Receptor, Cannabinoid, CB1 [D12.776.543.750.695.125.100]

Below are MeSH descriptors whose meaning is related to "Receptor, Cannabinoid, CB1".

Below are MeSH descriptors whose meaning is more specific than "Receptor, Cannabinoid, CB1".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Receptor, Cannabinoid, CB1" by people in this website by year, and whether "Receptor, Cannabinoid, CB1" was a major or minor topic of these publications.

Bar chart showing 10 publications over 7 distinct years, with a maximum of 3 publications in 2017

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2005	1	0	1
2006	0	1	1
2009	1	1	2
2013	1	0	1
2014	1	0	1
2017	3	0	3
2023	0	1	1

Below are the most recent publications written about "Receptor, Cannabinoid, CB1" by people in Profiles.

Kondev V, Najeed M, Yasmin F, Morgan A, Loomba N, Johnson K, Adank DN, Dong A, Delpire E, Li Y, Winder D, Grueter BA, Patel S. Endocannabinoid release at ventral hippocampal-amygdala synapses regulates stress-induced behavioral adaptation. Cell Rep. 2023 09 26; 42(9):113027.

View in: PubMed
Tahtouh T, Durieu E, Villiers B, Bruy?re C, Nguyen TL, Fant X, Ahn KH, Khurana L, Deau E, Lindberg MF, S?v?re E, Miege F, Roche D, Limanton E, L'Helgoual'ch JM, Burgy G, Guiheneuf S, Herault Y, Kendall DA, Carreaux F, Bazureau JP, Meijer L. Structure-Activity Relationship in the Leucettine Family of Kinase Inhibitors. J Med Chem. 2022 01 27; 65(2):1396-1417.

View in: PubMed
Folgueira C, Barja-Fernandez S, Prado L, Al-Massadi O, Castelao C, Pena-Leon V, Gonzalez-Saenz P, Baltar J, Baamonde I, Leis R, Dieguez C, Pagotto U, Casanueva FF, Tovar SA, Nogueiras R, Seoane LM. Pharmacological inhibition of cannabinoid receptor 1 stimulates gastric release of nesfatin-1 via the mTOR pathway. World J Gastroenterol. 2017 Sep 21; 23(35):6403-6411.

View in: PubMed
Jourdan T, Nicoloro SM, Zhou Z, Shen Y, Liu J, Coffey NJ, Cinar R, Godlewski G, Gao B, Aouadi M, Czech MP, Kunos G. Decreasing CB1 receptor signaling in Kupffer cells improves insulin sensitivity in obese mice. Mol Metab. 2017 11; 6(11):1517-1528.

View in: PubMed
Khurana L, Mackie K, Piomelli D, Kendall DA. Modulation of CB1 cannabinoid receptor by allosteric ligands: Pharmacology and therapeutic opportunities. Neuropharmacology. 2017 Sep 15; 124:3-12.

View in: PubMed
Khurana L, Fu BQ, Duddupudi AL, Liao YH, Immadi SS, Kendall DA, Lu D. Pyrimidinyl Biphenylureas: Identification of New Lead Compounds as Allosteric Modulators of the Cannabinoid Receptor CB1. J Med Chem. 2017 02 09; 60(3):1089-1104.

View in: PubMed
Jourdan T, Szanda G, Cinar R, Godlewski G, Holovac DJ, Park JK, Nicoloro S, Shen Y, Liu J, Rosenberg AZ, Liu Z, Czech MP, Kunos G. Developmental Role of Macrophage Cannabinoid-1 Receptor Signaling in Type 2 Diabetes. Diabetes. 2017 04; 66(4):994-1007.

View in: PubMed
Shim JY, Khurana L, Kendall DA. Computational analysis of the CB1 carboxyl-terminus in the receptor-G protein complex. Proteins. 2016 Apr; 84(4):532-43.

View in: PubMed
Tepper MA, Zurier RB, Burstein SH. Ultrapure ajulemic acid has improved CB2 selectivity with reduced CB1 activity. Bioorg Med Chem. 2014 Jul 01; 22(13):3245-51.

View in: PubMed
Khurana L, Ali HI, Olszewska T, Ahn KH, Damaraju A, Kendall DA, Lu D. Optimization of chemical functionalities of indole-2-carboxamides to improve allosteric parameters for the cannabinoid receptor 1 (CB1). J Med Chem. 2014 Apr 10; 57(7):3040-52.

View in: PubMed

People

Explore

Similar Concepts

Top Journals