 Antigens, CD59
"Antigens, CD59" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Small glycoproteins found on both hematopoietic and non-hematopoietic cells. CD59 restricts the cytolytic activity of homologous complement by binding to C8 and C9 and blocking the assembly of the membrane attack complex. (From Barclay et al., The Leukocyte Antigen FactsBook, 1993, p234)
| Descriptor ID |
D018957
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| MeSH Number(s) |
D12.776.395.550.448.140 D12.776.543.484.500.140 D12.776.543.550.418.140 D23.050.301.264.035.159 D23.101.100.110.159
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| Concept/Terms |
Antigens, CD59- Antigens, CD59
- CD59 Antigens
- Homologous Restriction Factor 20
- Protectin
- MACIF
- Membrane Attack Complex Inhibition Factor
- Membrane Inhibitor of Reactive Lysis
- CD59 Antigen
- HRF20
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Below are MeSH descriptors whose meaning is more general than "Antigens, CD59".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Glycoproteins [D12.776.395]
- Membrane Glycoproteins [D12.776.395.550]
- GPI-Linked Proteins [D12.776.395.550.448]
- Antigens, CD59 [D12.776.395.550.448.140]
- Membrane Proteins [D12.776.543]
- Lipid-Linked Proteins [D12.776.543.484]
- GPI-Linked Proteins [D12.776.543.484.500]
- Antigens, CD59 [D12.776.543.484.500.140]
- Membrane Glycoproteins [D12.776.543.550]
- GPI-Linked Proteins [D12.776.543.550.418]
- Antigens, CD59 [D12.776.543.550.418.140]
- Biological Factors [D23]
- Antigens [D23.050]
- Antigens, Surface [D23.050.301]
- Antigens, Differentiation [D23.050.301.264]
- Antigens, CD [D23.050.301.264.035]
- Antigens, CD59 [D23.050.301.264.035.159]
- Biological Markers [D23.101]
- Antigens, Differentiation [D23.101.100]
- Antigens, CD [D23.101.100.110]
- Antigens, CD59 [D23.101.100.110.159]
Below are MeSH descriptors whose meaning is more specific than "Antigens, CD59".
This graph shows the total number of publications written about "Antigens, CD59" by people in this website by year, and whether "Antigens, CD59" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 | | 1996 | 0 | 1 | 1 | | 1998 | 0 | 1 | 1 | | 2005 | 1 | 0 | 1 | | 2008 | 0 | 1 | 1 | | 2014 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Antigens, CD59" by people in Profiles.
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DeZern AE, Uknis M, Yuan X, Mukhina GL, Varela J, Saye J, Pu J, Brodsky RA. Complement blockade with a C1 esterase inhibitor in paroxysmal nocturnal hemoglobinuria. Exp Hematol. 2014 Oct; 42(10):857-61.e1.
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Wang SA, Pozdnyakova O, Jorgensen JL, Medeiros LJ, Stachurski D, Anderson M, Raza A, Woda BA. Detection of paroxysmal nocturnal hemoglobinuria clones in patients with myelodysplastic syndromes and related bone marrow diseases, with emphasis on diagnostic pitfalls and caveats. Haematologica. 2009 Jan; 94(1):29-37.
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Qin X, Dobarro M, Bedford SJ, Ferris S, Miranda PV, Song W, Bronson RT, Visconti PE, Halperin JA. Further characterization of reproductive abnormalities in mCd59b knockout mice: a potential new function of mCd59 in male reproduction. J Immunol. 2005 Nov 15; 175(10):6294-302.
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Solomon KR, Mallory MA, Finberg RW. Determination of the non-ionic detergent insolubility and phosphoprotein associations of glycosylphosphatidylinositol-anchored proteins expressed on T cells. Biochem J. 1998 Sep 1; 334 ( Pt 2):325-33.
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Solomon KR, Rudd CE, Finberg RW. The association between glycosylphosphatidylinositol-anchored proteins and heterotrimeric G protein alpha subunits in lymphocytes. Proc Natl Acad Sci U S A. 1996 Jun 11; 93(12):6053-8.
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Solomon KR, Chan M, Finberg RW. Expression of GPI-anchored complement regulatory proteins CD55 and CD59 differentiates two subpopulations of human CD56+ CD3- lymphocytes (NK cells). Cell Immunol. 1995 Oct 15; 165(2):294-301.
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