Gene Rearrangement, B-Lymphocyte, Heavy Chain
"Gene Rearrangement, B-Lymphocyte, Heavy Chain" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Ordered rearrangement of B-lymphocyte variable gene regions of the IMMUNOGLOBULIN HEAVY CHAINS, thereby contributing to antibody diversity. It occurs during the first stage of differentiation of the IMMATURE B-LYMPHOCYTES.
|Gene Rearrangement, B-Lymphocyte, Heavy Chain
- Gene Rearrangement, B-Lymphocyte, Heavy Chain
- B-Cell Heavy Chain Gene Rearrangement
- B-Lymphocyte Heavy Chain Gene Rearrangement
- B Cell Heavy Chain Gene Rearrangement
- B Lymphocyte Heavy Chain Gene Rearrangement
Below are MeSH descriptors whose meaning is more general than "Gene Rearrangement, B-Lymphocyte, Heavy Chain".
Below are MeSH descriptors whose meaning is more specific than "Gene Rearrangement, B-Lymphocyte, Heavy Chain".
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Below are the most recent publications written about "Gene Rearrangement, B-Lymphocyte, Heavy Chain" by people in Profiles.
Selimyan R, Gerstein RM, Ivanova I, Precht P, Subrahmanyam R, Perlot T, Alt FW, Sen R. Localized DNA demethylation at recombination intermediates during immunoglobulin heavy chain gene assembly. PLoS Biol. 2013; 11(1):e1001475.
Pozdnyakova O, Morgan EA, Li B, Shahsafaei A, Dorfman DM. Patterns of expression of CD56 and CD117 on neoplastic plasma cells and association with genetically distinct subtypes of plasma cell myeloma. Leuk Lymphoma. 2012 Oct; 53(10):1905-10.
Nakajima PB, Kiefer K, Price A, Bosma GC, Bosma MJ. Two distinct populations of H chain-edited B cells show differential surrogate L chain dependence. J Immunol. 2009 Mar 15; 182(6):3583-96.
Cerny J, Slavickova A, Krepelova A, Trneny M, Karban J, Klener P. Biallelic IgH rearrangements in patients with indolent lymphoproliferative disorders: molecular and practical implications. J Cell Physiol. 2004 May; 199(2):217-26.
Paul E, Lutz J, Erikson J, Carroll MC. Germinal center checkpoints in B cell tolerance in 3H9 transgenic mice. Int Immunol. 2004 Feb; 16(2):377-84.
Cerny J, Slavickova A, Krepelova A, Trneny M, Karban J, Klener P. Unusual sequence of VDJ rearrangement revealed by molecular analysis in a patient with indolent lymphoma. Haematologica. 2003 May; 88(5):ECR15.
Rossi MI, Medina KL, Garrett K, Kolar G, Comp PC, Shultz LD, Capra JD, Wilson P, Schipul A, Kincade PW. Relatively normal human lymphopoiesis but rapid turnover of newly formed B cells in transplanted nonobese diabetic/SCID mice. J Immunol. 2001 Sep 15; 167(6):3033-42.
Luby TM, Schrader CE, Stavnezer J, Selsing E. The mu switch region tandem repeats are important, but not required, for antibody class switch recombination. J Exp Med. 2001 Jan 15; 193(2):159-68.
Miyamoto A, Kunisada T, Yamazaki H, Miyake K, Nishikawa SI, Sudo T, Shultz LD, Hayashi SI. Establishment and characterization of pro-B cell lines from motheaten mutant mouse defective in SHP-1 protein tyrosine phosphatase. Immunol Lett. 1998 Sep; 63(2):75-82.
Dunnick W, Stavnezer J. Copy choice mechanism of immunoglobulin heavy-chain switch recombination. Mol Cell Biol. 1990 Jan; 10(1):397-400.