Gene Rearrangement, B-Lymphocyte
"Gene Rearrangement, B-Lymphocyte" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Ordered rearrangement of B-lymphocyte variable gene regions coding for the IMMUNOGLOBULIN CHAINS, thereby contributing to antibody diversity. It occurs during the differentiation of the IMMATURE B-LYMPHOCYTES.
| Descriptor ID |
D015322
|
| MeSH Number(s) |
G05.344.401 G12.500.274
|
| Concept/Terms |
Gene Rearrangement, B-Lymphocyte- Gene Rearrangement, B-Lymphocyte
- Gene Rearrangement, B Lymphocyte
- B-Lymphocyte Gene Rearrangement
- B Lymphocyte Gene Rearrangement
- B-Lymphocyte Gene Rearrangements
- Gene Rearrangements, B-Lymphocyte
- Rearrangement, B-Lymphocyte Gene
- Rearrangements, B-Lymphocyte Gene
- Gene Rearrangement, B-Cell
- B-Cell Gene Rearrangements
- Gene Rearrangement, B Cell
- Gene Rearrangements, B-Cell
- Rearrangement, B-Cell Gene
- Rearrangements, B-Cell Gene
- B-Cell Gene Rearrangement
- B Cell Gene Rearrangement
|
Below are MeSH descriptors whose meaning is more general than "Gene Rearrangement, B-Lymphocyte".
Below are MeSH descriptors whose meaning is more specific than "Gene Rearrangement, B-Lymphocyte".
This graph shows the total number of publications written about "Gene Rearrangement, B-Lymphocyte" by people in this website by year, and whether "Gene Rearrangement, B-Lymphocyte" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 1997 | 1 | 0 | 1 |
| 1999 | 0 | 1 | 1 |
| 2005 | 2 | 0 | 2 |
| 2009 | 1 | 0 | 1 |
| 2010 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Gene Rearrangement, B-Lymphocyte" by people in Profiles.
-
Khair L, Guikema JE, Linehan EK, Ucher AJ, Leus NG, Ogilvie C, Lou Z, Schrader CE, Stavnezer J. ATM increases activation-induced cytidine deaminase activity at downstream S regions during class-switch recombination. J Immunol. 2014 May 15; 192(10):4887-96.
-
Schroeder HW, Cavacini L. Structure and function of immunoglobulins. J Allergy Clin Immunol. 2010 Feb; 125(2 Suppl 2):S41-52.
-
Stavnezer J, Kang J. The surprising discovery that TGF beta specifically induces the IgA class switch. J Immunol. 2009 Jan 01; 182(1):5-7.
-
Borghesi L, Aites J, Nelson S, Lefterov P, James P, Gerstein R. E47 is required for V(D)J recombinase activity in common lymphoid progenitors. J Exp Med. 2005 Dec 19; 202(12):1669-77.
-
Schrader CE, Linehan EK, Mochegova SN, Woodland RT, Stavnezer J. Inducible DNA breaks in Ig S regions are dependent on AID and UNG. J Exp Med. 2005 Aug 15; 202(4):561-8.
-
Pederson T. The immunome. Mol Immunol. 1999 Oct-Nov; 36(15-16):1127-8.
-
Meyer A, Parng CL, Hansal SA, Osborne BA, Goldsby RA. Immunoglobulin gene diversification in cattle. Int Rev Immunol. 1997; 15(3-4):165-83.
-
Kuhn-Hallek I, Sage DR, Stein L, Groelle H, Fingeroth JD. Expression of recombination activating genes (RAG-1 and RAG-2) in Epstein-Barr virus-bearing B cells. Blood. 1995 Mar 01; 85(5):1289-99.
-
Shockett P, Stavnezer J. Inhibitors of poly(ADP-ribose) polymerase increase antibody class switching. J Immunol. 1993 Dec 15; 151(12):6962-76.