Gene Rearrangement, B-Lymphocyte, Light Chain
"Gene Rearrangement, B-Lymphocyte, Light Chain" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Ordered rearrangement of B-lymphocyte variable gene regions coding for the kappa or lambda IMMUNOGLOBULIN LIGHT CHAINS, thereby contributing to antibody diversity. It occurs during the second stage of differentiation of the IMMATURE B-LYMPHOCYTES.
| Descriptor ID |
D015328
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| MeSH Number(s) |
G05.344.401.601 G12.500.274.601
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| Concept/Terms |
Gene Rearrangement, B-Lymphocyte, Light Chain- Gene Rearrangement, B-Lymphocyte, Light Chain
- B-Cell Light Chain Gene Rearrangement
- B-Lymphocyte Light Chain Gene Rearrangement
- B Cell Light Chain Gene Rearrangement
- B Lymphocyte Light Chain Gene Rearrangement
|
Below are MeSH descriptors whose meaning is more general than "Gene Rearrangement, B-Lymphocyte, Light Chain".
Below are MeSH descriptors whose meaning is more specific than "Gene Rearrangement, B-Lymphocyte, Light Chain".
This graph shows the total number of publications written about "Gene Rearrangement, B-Lymphocyte, Light Chain" by people in this website by year, and whether "Gene Rearrangement, B-Lymphocyte, Light Chain" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
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Below are the most recent publications written about "Gene Rearrangement, B-Lymphocyte, Light Chain" by people in Profiles.
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Kiefer K, Nakajima PB, Oshinsky J, Seeholzer SH, Radic M, Bosma GC, Bosma MJ. Antigen receptor editing in anti-DNA transitional B cells deficient for surface IgM. J Immunol. 2008 May 01; 180(9):6094-106.
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Paul E, Lutz J, Erikson J, Carroll MC. Germinal center checkpoints in B cell tolerance in 3H9 transgenic mice. Int Immunol. 2004 Feb; 16(2):377-84.
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Jeong Y, Osborne BA, Goldsby RA. Early Vlambda diversification in sheep. Immunology. 2001 May; 103(1):26-34.
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Lucier MR, Thompson RE, Waire J, Lin AW, Osborne BA, Goldsby RA. Multiple sites of V lambda diversification in cattle. J Immunol. 1998 Nov 15; 161(10):5438-44.
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Parng CL, Hansal S, Goldsby RA, Osborne BA. Gene conversion contributes to Ig light chain diversity in cattle. J Immunol. 1996 Dec 15; 157(12):5478-86.
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Hunt SV, Medlock ES, Greiner DL, Goldschneider I, Opstelten D. Rat immunoglobulin genes have comparable patterns of JH rearrangement in normal peripheral B cells and in pre-B and cultured TdT+ cells from bone marrow. Adv Exp Med Biol. 1988; 237:63-8.