 Osteoblasts
"Osteoblasts" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Bone-forming cells which secrete an EXTRACELLULAR MATRIX. HYDROXYAPATITE crystals are then deposited into the matrix to form bone.
| Descriptor ID |
D010006
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| MeSH Number(s) |
A11.329.629
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Osteoblasts".
Below are MeSH descriptors whose meaning is more specific than "Osteoblasts".
This graph shows the total number of publications written about "Osteoblasts" by people in this website by year, and whether "Osteoblasts" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1990 | 2 | 0 | 2 | | 1992 | 0 | 1 | 1 | | 1999 | 0 | 1 | 1 | | 2001 | 2 | 0 | 2 | | 2002 | 2 | 3 | 5 | | 2003 | 3 | 3 | 6 | | 2004 | 7 | 3 | 10 | | 2005 | 4 | 2 | 6 | | 2006 | 4 | 1 | 5 | | 2007 | 3 | 5 | 8 | | 2008 | 9 | 7 | 16 | | 2009 | 9 | 4 | 13 | | 2010 | 5 | 4 | 9 | | 2011 | 5 | 4 | 9 | | 2012 | 4 | 2 | 6 | | 2013 | 5 | 4 | 9 | | 2014 | 4 | 2 | 6 | | 2015 | 3 | 2 | 5 | | 2016 | 3 | 2 | 5 | | 2017 | 2 | 0 | 2 | | 2018 | 0 | 2 | 2 | | 2019 | 0 | 1 | 1 | | 2020 | 1 | 2 | 3 |
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Below are the most recent publications written about "Osteoblasts" by people in Profiles.
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Bok S, Shin DY, Yallowitz AR, Eiseman M, Cung M, Xu R, Li N, Sun J, Williams AL, Scott JE, Su B, Shim JH, Greenblatt MB. MEKK2 mediates aberrant ERK activation in neurofibromatosis type I. Nat Commun. 2020 11 11; 11(1):5704.
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Li Z, Oh H, Cung M, Marquez SJ, Sun J, Hammad H, Janssens S, Pouliot P, Lambrecht BN, Yang YS, Shim JH, Greenblatt MB. TAOK3 is a MAP3K contributing to osteoblast differentiation and skeletal mineralization. Biochem Biophys Res Commun. 2020 10 22; 531(4):497-502.
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Kim JM, Yang YS, Park KH, Ge X, Xu R, Li N, Song M, Chun H, Bok S, Charles JF, Filhol-Cochet O, Boldyreff B, Dinter T, Yu PB, Kon N, Gu W, Takarada T, Greenblatt MB, Shim JH. A RUNX2 stabilization pathway mediates physiologic and pathologic bone formation. Nat Commun. 2020 05 08; 11(1):2289.
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Kim JM, Yang YS, Park KH, Oh H, Greenblatt MB, Shim JH. The ERK MAPK Pathway Is Essential for Skeletal Development and Homeostasis. Int J Mol Sci. 2019 Apr 12; 20(8).
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Debnath S, Yallowitz AR, McCormick J, Lalani S, Zhang T, Xu R, Li N, Liu Y, Yang YS, Eiseman M, Shim JH, Hameed M, Healey JH, Bostrom MP, Landau DA, Greenblatt MB. Discovery of a periosteal stem cell mediating intramembranous bone formation. Nature. 2018 10; 562(7725):133-139.
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Xu R, Yallowitz A, Qin A, Wu Z, Shin DY, Kim JM, Debnath S, Ji G, Bostrom MP, Yang X, Zhang C, Dong H, Kermani P, Lalani S, Li N, Liu Y, Poulos MG, Wach A, Zhang Y, Inoue K, Di Lorenzo A, Zhao B, Butler JM, Shim JH, Glimcher LH, Greenblatt MB. Targeting skeletal endothelium to ameliorate bone loss. Nat Med. 2018 06; 24(6):823-833.
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Tai PWL, Wu H, van Wijnen AJ, Stein GS, Stein JL, Lian JB. Genome-wide DNase hypersensitivity, and occupancy of RUNX2 and CTCF reveal a highly dynamic gene regulome during MC3T3 pre-osteoblast differentiation. PLoS One. 2017; 12(11):e0188056.
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Sepulveda H, Aguilar R, Prieto CP, Bustos F, Aedo S, Lattus J, van Zundert B, Palma V, Montecino M. Epigenetic Signatures at the RUNX2-P1 and Sp7 Gene Promoters Control Osteogenic Lineage Commitment of Umbilical Cord-Derived Mesenchymal Stem Cells. J Cell Physiol. 2017 Sep; 232(9):2519-2527.
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Cam M, Gardner HL, Roberts RD, Fenger JM, Guttridge DC, London CA, Cam H. ?Np63 mediates cellular survival and metastasis in canine osteosarcoma. Oncotarget. 2016 Jul 26; 7(30):48533-48546.
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Camci-Unal G, Laromaine A, Hong E, Derda R, Whitesides GM. Biomineralization Guided by Paper Templates. Sci Rep. 2016 06 09; 6:27693.
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