Poly(ADP-ribose) Polymerases

"Poly(ADP-ribose) Polymerases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Enzymes that catalyze the transfer of multiple ADP-RIBOSE groups from nicotinamide-adenine dinucleotide (NAD) onto protein targets, thus building up a linear or branched homopolymer of repeating ADP-ribose units i.e., POLY ADENOSINE DIPHOSPHATE RIBOSE.

Descriptor ID	D011065
MeSH Number(s)	D08.811.913.400.725.115.690
Concept/Terms	Poly(ADP-ribose) Polymerases Poly(ADP-ribose) Polymerases ADP-Ribosyltransferase (Polymerizing) Poly(ADP-ribose) Polymerase Poly ADP Ribose Polymerase Poly ADP Ribose Transferase Poly(ADP-Ribose) Transferase PARP Polymerase Polymerase, PARP Poly(ADPribose) Polymerase Poly ADP-Ribose Synthase Poly ADP Ribose Synthase Synthase, Poly ADP-Ribose Poly(ADPR) Polymerase Poly(ADP-Ribose) Synthase

Below are MeSH descriptors whose meaning is more general than "Poly(ADP-ribose) Polymerases".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Transferases [D08.811.913]
Glycosyltransferases [D08.811.913.400]
Pentosyltransferases [D08.811.913.400.725]
ADP Ribose Transferases [D08.811.913.400.725.115]
Poly(ADP-ribose) Polymerases [D08.811.913.400.725.115.690]

Below are MeSH descriptors whose meaning is related to "Poly(ADP-ribose) Polymerases".

Below are MeSH descriptors whose meaning is more specific than "Poly(ADP-ribose) Polymerases".

Poly(ADP-ribose) Polymerases
Poly (ADP-Ribose) Polymerase-1
Tankyrases

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Poly(ADP-ribose) Polymerases" by people in this website by year, and whether "Poly(ADP-ribose) Polymerases" was a major or minor topic of these publications.

Bar chart showing 24 publications over 16 distinct years, with a maximum of 4 publications in 2013

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1997	1	0	1
1998	0	1	1
1999	1	2	3
2001	0	3	3
2002	0	1	1
2003	0	2	2
2004	0	1	1
2007	1	0	1
2009	1	0	1
2010	0	1	1
2013	2	2	4
2014	0	1	1
2015	0	1	1
2016	0	1	1
2019	0	1	1
2020	0	1	1

Below are the most recent publications written about "Poly(ADP-ribose) Polymerases" by people in Profiles.

Medina MA, Oza G, Sharma A, Arriaga LG, Hern?ndez Hern?ndez JM, Rotello VM, Ramirez JT. Triple-Negative Breast Cancer: A Review of Conventional and Advanced Therapeutic Strategies. Int J Environ Res Public Health. 2020 03 20; 17(6).

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Cimadamore A, Lopez-Beltran A, Massari F, Santoni M, Mazzucchelli R, Scarpelli M, Galosi AB, Cheng L, Montironi R. Germline and somatic mutations in prostate cancer: focus on defective DNA repair, PARP inhibitors and immunotherapy. Future Oncol. 2020 Feb; 16(5):75-80.

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Ralto KM, Rhee EP, Parikh SM. NAD+ homeostasis in renal health and disease. Nat Rev Nephrol. 2020 02; 16(2):99-111.

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Ray Chaudhuri A, Callen E, Ding X, Gogola E, Duarte AA, Lee JE, Wong N, Lafarga V, Calvo JA, Panzarino NJ, John S, Day A, Crespo AV, Shen B, Starnes LM, de Ruiter JR, Daniel JA, Konstantinopoulos PA, Cortez D, Cantor SB, Fernandez-Capetillo O, Ge K, Jonkers J, Rottenberg S, Sharan SK, Nussenzweig A. Replication fork stability confers chemoresistance in BRCA-deficient cells. Nature. 2016 07 21; 535(7612):382-7.

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Massari F, Santoni M, Ciccarese C, Brunelli M, Conti A, Santini D, Montironi R, Cascinu S, Tortora G. Emerging concepts on drug resistance in bladder cancer: Implications for future strategies. Crit Rev Oncol Hematol. 2015 Oct; 96(1):81-90.

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Jog NR, Caricchio R. 17? estradiol regulates adhesion molecule expression in mesangial cells during glomerulonephritis. Clin Immunol. 2015 Jul; 159(1):13-22.

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Sun YR, Zhang SH, Shao RG, He HW. [The synergistic effect of lidamycin and rituximab on human B cell lymphoma]. Yao Xue Xue Bao. 2014 Feb; 49(2):198-203.

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Malhotra U, Zaidi AH, Kosovec JE, Kasi PM, Komatsu Y, Rotoloni CL, Davison JM, R C, Hoppo T, Nason KS, Kelly LA, Gibson MK, Jobe BA. Prognostic value and targeted inhibition of survivin expression in esophageal adenocarcinoma and cancer-adjacent squamous epithelium. PLoS One. 2013; 8(11):e78343.

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Venere M, Hamerlik P, Wu Q, Rasmussen RD, Song LA, Vasanji A, Tenley N, Flavahan WA, Hjelmeland AB, Bartek J, Rich JN. Therapeutic targeting of constitutive PARP activation compromises stem cell phenotype and survival of glioblastoma-initiating cells. Cell Death Differ. 2014 Feb; 21(2):258-69.

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Jog NR, Caricchio R. Differential regulation of cell death programs in males and females by Poly (ADP-Ribose) Polymerase-1 and 17? estradiol. Cell Death Dis. 2013 Aug 08; 4:e758.

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